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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer maturation
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Accession:GO:0021686 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEND1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4830814|PMID:20153830)
GO_Central
MGI
PMID:20153830 PMID:21873635 MGI:4830814 NCBI chr11:787,115...790,090
Ensembl chr11:787,115...790,113
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    developmental process 7222
      anatomical structure development 6546
        anatomical structure maturation 310
          cerebellar granular layer maturation 1
Path 2
Term Annotations click to browse term
  biological_process 18537
    developmental process 7222
      anatomical structure development 6546
        multicellular organism development 5918
          system development 5591
            nervous system development 2898
              central nervous system development 1332
                brain development 1014
                  hindbrain development 225
                    metencephalon development 170
                      cerebellum development 156
                        cerebellar cortex development 70
                          cerebellar granular layer development 18
                            cerebellar granular layer maturation 1
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