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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer formation
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Accession:GO:0021684 term browser browse the term
Definition:The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chr13:66,526,508...66,897,125
Ensembl chr13:66,528,322...66,897,128
JBrowse link
G CBLN1 cerebellin 1 precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:35,516,097...35,518,080
Ensembl chr 6:35,515,754...35,519,518
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:125,821,195...127,130,617
Ensembl chr 8:125,819,951...126,434,793
JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3769586|PMID:17984326) Ensembl
MGI
PMID:17984326 GO_REF:0000107 MGI:3769586 NCBI chr14:141,132,374...141,188,343
Ensembl chr14:141,132,350...141,188,342
JBrowse link
G MTPN myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chr18:13,330,049...13,395,297
Ensembl chr18:13,330,091...13,400,046
JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (MGI:5436217|PMID:21800304) MGI PMID:21800304 MGI:5436217 NCBI chr 2:65,954,808...66,056,591
Ensembl chr 2:65,954,244...66,056,567
JBrowse link
G NRXN1 neurexin 1 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr 3:89,799,426...90,914,205
Ensembl chr 3:89,799,543...90,914,205
JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:54,056,504...54,617,045
Ensembl chr  X:53,884,012...54,616,960
JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:129,527,704...129,583,693
Ensembl chr 9:129,532,164...129,580,979
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr12:22,001,300...22,028,452
Ensembl chr12:22,001,336...22,028,454
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:1351063|PMID:10624947) MGI PMID:10624947 MGI:1351063 NCBI chr14:23,423,693...23,448,130
Ensembl chr14:23,423,696...23,448,138
JBrowse link
G WNT7A Wnt family member 7A acts_upstream_of_or_within ISO (MGI:1195230|PMID:9405095) MGI PMID:9405095 MGI:1195230 NCBI chr13:70,538,802...70,602,464
Ensembl chr13:70,538,894...70,602,455
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    developmental process 6309
      anatomical structure formation involved in morphogenesis 1200
        cerebellar granular layer formation 12
          cerebellar Golgi cell differentiation 0
          cerebellar granule cell differentiation 12
          cerebellar unipolar brush cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 16579
    developmental process 6309
      anatomical structure development 5828
        multicellular organism development 5300
          system development 4990
            nervous system development 2604
              central nervous system development 1221
                brain development 948
                  hindbrain development 220
                    metencephalon development 167
                      cerebellum development 153
                        cerebellar cortex development 68
                          cerebellar granular layer development 18
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation 12
                                cerebellar Golgi cell differentiation 0
                                cerebellar granule cell differentiation 12
                                cerebellar unipolar brush cell differentiation 0
paths to the root