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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar granular layer formation
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Accession:GO:0021684 term browser browse the term
Definition:The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (PMID:9668038) RGD PMID:9668038 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Cbln1 cerebellin 1 precursor involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q61625 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 acts_upstream_of_or_within ISO (PMID:17984326) RGD PMID:17984326 NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362 		JBrowse link
G Mtpn myotrophin IEP RGD PMID:8144589 RGD:632797 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Nfix nuclear factor I X involved_in
acts_upstream_of_or_within		 ISO MGI:3802571 (PMID:23042739)
MGI:3802571 (PMID:21800304)		 RGD PMID:21800304 PMID:23042739 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q61625|UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO (PMID:27160703) RGD PMID:27160703 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:4849596|PMID:20808958) RGD PMID:20808958 MGI:4849596 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (PMID:10624947) RGD PMID:10624947 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Wnt7a Wnt family member 7A acts_upstream_of_or_within ISO (PMID:9405095) RGD PMID:9405095 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure formation involved in morphogenesis 1379
        cerebellar granular layer formation 12
          cerebellar Golgi cell differentiation 0
          cerebellar granule cell differentiation 12
          cerebellar unipolar brush cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            nervous system development 2835
              central nervous system development 1216
                brain development 912
                  hindbrain development 229
                    metencephalon development 175
                      cerebellum development 161
                        cerebellar cortex development 72
                          cerebellar granular layer development 18
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation 12
                                cerebellar Golgi cell differentiation 0
                                cerebellar granule cell differentiation 12
                                cerebellar unipolar brush cell differentiation 0
paths to the root