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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer morphogenesis
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Accession:GO:0021683 term browser browse the term
Definition:The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within ISO (MGI:3709698|PMID:17409116) MGI PMID:17409116 MGI:3709698 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
cerebellar granular layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF14 kinesin family member 14 involved_in ISO (MGI:5485315|PMID:23308235) UniProt PMID:23308235 MGI:5485315 NCBI chr 7:2,548,407...2,602,371
Ensembl chr 7:2,548,258...2,601,581
JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chr20:7,665,468...8,037,407
Ensembl chr20:7,749,807...8,034,474
JBrowse link
G CBLN1 cerebellin 1 precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,974,989...65,978,464
Ensembl chr 2:65,974,981...65,977,179
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr32:15,322,256...16,787,966
Ensembl chr32:15,322,738...16,753,656
JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 acts_upstream_of_or_within ISO (MGI:3769586|PMID:17984326) MGI PMID:17984326 MGI:3769586 NCBI chr28:40,757,950...40,790,603 JBrowse link
G MTPN myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chr16:12,316,487...12,369,148
Ensembl chr16:12,316,336...12,369,387
JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (MGI:5436217|PMID:21800304) MGI PMID:21800304 MGI:5436217 NCBI chr20:49,117,087...49,187,023
Ensembl chr20:49,117,943...49,214,788
JBrowse link
G NRXN1 neurexin 1 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr10:51,555,660...52,666,774
Ensembl chr10:51,558,452...52,667,569
JBrowse link
G OPHN1 oligophrenin 1 involved_in ISO (PMID:27160703) ARUK-UCL PMID:27160703 NCBI chr  X:52,418,390...52,983,155
Ensembl chr  X:52,455,373...52,982,244
JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,996,282...12,047,693
Ensembl chr 7:11,996,703...12,044,036
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:1351063|PMID:10624947) MGI PMID:10624947 MGI:1351063 NCBI chr26:968,714...982,244
Ensembl chr26:970,138...982,229
JBrowse link
G WNT7A Wnt family member 7A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1195230|PMID:9405095) Ensembl
MGI
PMID:9405095 GO_REF:0000107 MGI:1195230 NCBI chr20:4,072,010...4,139,521
Ensembl chr20:4,073,929...4,139,436
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13872
    developmental process 6138
      anatomical structure morphogenesis 2710
        cerebellar granular layer morphogenesis 14
          cerebellar granular layer formation + 12
          cerebellar granular layer structural organization 1
Path 2
Term Annotations click to browse term
  biological_process 13872
    developmental process 6138
      anatomical structure development 5709
        multicellular organism development 5207
          system development 4900
            nervous system development 2524
              central nervous system development 1205
                brain development 942
                  hindbrain development 218
                    metencephalon development 164
                      cerebellum development 150
                        cerebellum morphogenesis 56
                          cerebellar cortex morphogenesis 45
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation + 12
                              cerebellar granular layer structural organization 1
paths to the root