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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar granular layer development
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Accession:GO:0021681 term browser browse the term
Definition:The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in IMP (MGI:5295128|PMID:21957071) UniProt PMID:21957071 MGI:5295128 NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046 		JBrowse link
G Mdk midkine involved_in IMP (MGI:2178952|PMID:10096022) DFLAT PMID:10096022 MGI:2178952 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in IMP (MGI:5700621|PMID:26323690) ARUK-UCL PMID:26323690 MGI:5700621 NCBI chr 2:120,563,297...120,681,111
Ensembl chr 2:120,563,297...120,681,085 		JBrowse link
cerebellar granular layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cend1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:20153830) GO_Central
MGI		 PMID:20153830 GO_REF:0000033 NCBI chr 7:141,006,359...141,009,475
Ensembl chr 7:141,006,359...141,009,404 		JBrowse link
cerebellar granular layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 acts_upstream_of_or_within IMP (PMID:17409116) MGI PMID:17409116 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
cerebellar granular layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif14 kinesin family member 14 involved_in IMP (MGI:5485315|PMID:23308235) UniProt PMID:23308235 MGI:5485315 NCBI chr 1:136,394,044...136,483,676
Ensembl chr 1:136,394,081...136,459,249 		JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 acts_upstream_of_or_within IMP (PMID:9668038) MGI PMID:9668038 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574 		JBrowse link
G Cbln1 cerebellin 1 precursor protein involved_in IGI (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr 8:88,195,481...88,199,220
Ensembl chr 8:88,195,033...88,199,237 		JBrowse link
G Grid2 glutamate receptor, ionotropic, delta 2 involved_in IGI (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr 6:63,230,118...64,681,305
Ensembl chr 6:63,232,860...64,681,307 		JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain (KIND) containing 1 acts_upstream_of_or_within IMP (PMID:17984326) MGI PMID:17984326 NCBI chr 7:139,474,612...139,521,453
Ensembl chr 7:139,474,612...139,521,450 		JBrowse link
G Mtpn myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chr 6:35,485,759...35,516,823
Ensembl chr 6:35,485,841...35,516,823 		JBrowse link
G Nfix nuclear factor I/X involved_in
acts_upstream_of_or_within		 IMP (PMID:23042739)
(PMID:21800304)		 MGI PMID:21800304 PMID:23042739 NCBI chr 8:85,431,341...85,527,086
Ensembl chr 8:85,426,505...85,526,973 		JBrowse link
G Nrxn1 neurexin I involved_in IGI (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:97,597,886...97,934,691
Ensembl chr  X:97,597,883...97,934,631 		JBrowse link
G Prox1 prospero homeobox 1 involved_in IMP (MGI:4849596|PMID:20808958) BHF-UCL PMID:20808958 MGI:4849596 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Ulk1 unc-51 like kinase 1 acts_upstream_of_or_within IMP (PMID:10624947) MGI PMID:10624947 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
G Wnt7a wingless-type MMTV integration site family, member 7A acts_upstream_of_or_within IDA (PMID:9405095) MGI PMID:9405095 NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    developmental process 7363
      anatomical structure development 6834
        cerebellar granular layer development 18
          cerebellar granular layer maturation 1
          cerebellar granular layer morphogenesis + 14
Path 2
Term Annotations click to browse term
  biological_process 28573
    developmental process 7363
      anatomical structure development 6834
        multicellular organism development 5426
          system development 4651
            nervous system development 2845
              central nervous system development 1218
                brain development 909
                  hindbrain development 231
                    metencephalon development 178
                      cerebellum development 164
                        cerebellar cortex development 74
                          cerebellar granular layer development 18
                            cerebellar granular layer maturation 1
                            cerebellar granular layer morphogenesis + 14
paths to the root