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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar granular layer development
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Accession:GO:0021681 term browser browse the term
Definition:The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.

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cerebellar granular layer development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in ISO (MGI:5295128|PMID:21957071) UniProt PMID:21957071 MGI:5295128 NCBI chrNW_004955547:467,331...501,172
Ensembl chrNW_004955547:466,777...501,490 		JBrowse link
G Mdk midkine involved_in ISO (MGI:2178952|PMID:10096022) DFLAT PMID:10096022 MGI:2178952 NCBI chrNW_004955422:1,655,351...1,657,026
Ensembl chrNW_004955422:1,655,358...1,657,044 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (MGI:5700621|PMID:26323690) ARUK-UCL PMID:26323690 MGI:5700621 NCBI chrNW_004955416:9,412,297...9,518,561
Ensembl chrNW_004955416:9,412,297...9,559,655 		JBrowse link
cerebellar granular layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cend1 cell cycle exit and neuronal differentiation 1 acts_upstream_of_or_within ISO (PMID:20153830) MGI PMID:20153830 NCBI chrNW_004955476:11,339,586...11,341,996
Ensembl chrNW_004955476:11,339,586...11,341,996 		JBrowse link
cerebellar granular layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO (PMID:17409116) MGI PMID:17409116 NCBI chrNW_004955453:10,049,822...10,076,155
Ensembl chrNW_004955453:10,027,104...10,076,645 		JBrowse link
cerebellar granular layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif14 kinesin family member 14 involved_in ISO (MGI:5485315|PMID:23308235) UniProt PMID:23308235 MGI:5485315 NCBI chrNW_004955406:36,732,135...36,791,756
Ensembl chrNW_004955406:36,737,484...36,791,756 		JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (PMID:9668038) MGI PMID:9668038 NCBI chrNW_004955561:1,727,935...1,851,907
Ensembl chrNW_004955561:1,727,935...1,851,907 		JBrowse link
G Cbln1 cerebellin 1 precursor involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chrNW_004955433:7,516,487...7,519,929
Ensembl chrNW_004955433:7,516,487...7,519,929 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chrNW_004955405:3,291,793...4,411,249
Ensembl chrNW_004955405:3,344,763...4,443,836 		JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 acts_upstream_of_or_within ISO (PMID:17984326) MGI PMID:17984326 NCBI chrNW_004955477:10,792,066...10,850,457
Ensembl chrNW_004955477:10,792,394...10,850,186 		JBrowse link
G Mtpn myotrophin ISO RGD PMID:8144589 RGD:632797 NCBI chrNW_004955494:6,805,518...6,844,454
Ensembl chrNW_004955494:6,805,262...6,845,394 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within
involved_in		 ISO (PMID:21800304)
(PMID:23042739)		 MGI PMID:21800304 PMID:23042739 NCBI chrNW_004955415:32,055,926...32,121,611
Ensembl chrNW_004955415:32,055,375...32,117,833 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (MGI:4839424|PMID:20537373) BHF-UCL PMID:20537373 MGI:4839424 NCBI chrNW_004955441:16,230,977...17,178,003
Ensembl chrNW_004955441:16,234,070...17,178,005 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO (PMID:27160703) ARUK-UCL PMID:27160703 NCBI chrNW_004955475:7,576,629...8,019,132
Ensembl chrNW_004955475:7,581,675...8,018,139 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:4849596|PMID:20808958) BHF-UCL PMID:20808958 MGI:4849596 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chrNW_004955451:14,928,273...14,964,855
Ensembl chrNW_004955451:14,929,136...14,964,723 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (PMID:10624947) MGI PMID:10624947 NCBI chrNW_004955482:760,200...777,133
Ensembl chrNW_004955482:761,811...777,133 		JBrowse link
G Wnt7a Wnt family member 7A acts_upstream_of_or_within ISO (PMID:9405095) MGI PMID:9405095 NCBI chrNW_004955429:12,647,993...12,693,998
Ensembl chrNW_004955429:12,647,993...12,694,895 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    developmental process 5848
      anatomical structure development 5535
        cerebellar granular layer development 18
          cerebellar granular layer maturation 1
          cerebellar granular layer morphogenesis + 14
Path 2
Term Annotations click to browse term
  biological_process 12321
    developmental process 5848
      anatomical structure development 5535
        multicellular organism development 4546
          system development 3948
            nervous system development 2459
              central nervous system development 1090
                brain development 829
                  hindbrain development 218
                    metencephalon development 165
                      cerebellum development 151
                        cerebellar cortex development 70
                          cerebellar granular layer development 18
                            cerebellar granular layer maturation 1
                            cerebellar granular layer morphogenesis + 14
paths to the root