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ONTOLOGY REPORT - ANNOTATIONS

Term:cranial nerve morphogenesis
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Accession:GO:0021602 term browser browse the term
Definition:The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


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cranial nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within ISO (PMID:11694877) MGI PMID:11694877 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G PLXNA4 plexin A4 acts_upstream_of_or_within ISO (PMID:15814794) MGI PMID:15814794 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
abducens nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA1 homeobox A1 involved_in ISO (PMID:16155570) DFLAT PMID:16155570 NCBI chr 7:27,737,432...27,740,442
Ensembl chr 7:27,335,710...27,339,747 		JBrowse link
G MAFB MAF bZIP transcription factor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,023,988...37,027,446
Ensembl chr20:38,127,722...38,128,693 		JBrowse link
facial nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADARB1 adenosine deaminase RNA specific B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20826656) Ensembl
MGI		 PMID:20826656 GO_REF:0000107 NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748 		JBrowse link
G PLXNA4 plexin A4 acts_upstream_of_or_within ISO (PMID:15814794) MGI PMID:15814794 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12874121) Ensembl
MGI		 PMID:12874121 GO_REF:0000107 NCBI chr14:41,250,512...41,256,567
Ensembl chr14:59,515,324...59,527,494 		JBrowse link
facial nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR2 early growth response 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9806922) Ensembl
MGI		 PMID:9806922 GO_REF:0000107 NCBI chr10:59,320,073...59,326,869
Ensembl chr10:61,648,364...61,652,846 		JBrowse link
G HOXA1 homeobox A1 acts_upstream_of_or_within ISO (PMID:9806922) MGI PMID:9806922 NCBI chr 7:27,737,432...27,740,442
Ensembl chr 7:27,335,710...27,339,747 		JBrowse link
G HOXB1 homeobox B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8898234) Ensembl
MGI		 PMID:8898234 GO_REF:0000107 NCBI chr17:9,005,745...9,008,230
Ensembl chr17:9,190,137...9,191,696 		JBrowse link
G HOXB2 homeobox B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9012503) Ensembl
MGI		 PMID:9012503 GO_REF:0000107 NCBI chr17:8,991,652...8,994,092
Ensembl chr17:9,176,313...9,178,713 		JBrowse link
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G NRP2 neuropilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:92,911,721...93,027,032
Ensembl chr2B:211,042,324...211,157,547 		JBrowse link
G PLXNA3 plexin A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,900,029...143,915,391
Ensembl chr  X:153,772,700...153,786,167 		JBrowse link
G PLXNA4 plexin A4 involved_in ISO (MGI:3822054|PMID:18804103) ParkinsonsUK-UCL PMID:18804103 MGI:3822054 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
G SEMA3A semaphorin 3A involved_in ISO (MGI:3822054|PMID:18804103) ParkinsonsUK-UCL PMID:18804103 MGI:3822054 NCBI chr 7:75,929,699...76,484,246
Ensembl chr 7:89,590,359...90,004,122 		JBrowse link
G SEMA3F semaphorin 3F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:50,083,733...50,117,518
Ensembl chr 3:51,318,089...51,351,958 		JBrowse link
glossopharyngeal nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA3 homeobox A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9441667) Ensembl
MGI		 PMID:9441667 GO_REF:0000107 NCBI chr 7:27,750,642...27,767,125
Ensembl chr 7:27,350,491...27,371,169 		JBrowse link
G HOXB3 homeobox B3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9441667) Ensembl
MGI		 PMID:9441667 GO_REF:0000107 NCBI chr17:8,946,441...8,987,876
Ensembl chr17:9,147,784...9,171,021 		JBrowse link
G HOXD3 homeobox D3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9441667) Ensembl
MGI		 PMID:9441667 GO_REF:0000107 NCBI chr2B:63,432,720...63,452,816
Ensembl chr2B:181,141,538...181,161,604 		JBrowse link
G PLXNA4 plexin A4 acts_upstream_of_or_within ISO (PMID:15814794) MGI PMID:15814794 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
hypoglossal nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADARB1 adenosine deaminase RNA specific B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20826656) Ensembl
MGI		 PMID:20826656 GO_REF:0000107 NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748 		JBrowse link
oculomotor nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHOX2A paired like homeobox 2A involved_in ISO (MGI:1098916|PMID:9374403) BHF-UCL PMID:9374403 MGI:1098916 NCBI chr11:67,317,747...67,322,850 JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (MGI:80519|PMID:8622766) UniProt PMID:8622766 MGI:80519 NCBI chr 6:10,237,834...10,260,843 JBrowse link
olfactory nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLXNA1 plexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:124,026,069...124,080,241
Ensembl chr 3:131,340,584...131,393,561 		JBrowse link
G PLXNA3 plexin A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,900,029...143,915,391
Ensembl chr  X:153,772,700...153,786,167 		JBrowse link
olfactory nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMD dystrophin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18586242) Ensembl
MGI		 PMID:18586242 GO_REF:0000107 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
optic nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:11344259)
(PMID:12097474)		 MGI PMID:11344259 PMID:12097474 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361 		JBrowse link
G EPHB1 EPH receptor B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12971893) Ensembl
MGI		 PMID:12971893 GO_REF:0000107 NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802 		JBrowse link
G EPHB2 EPH receptor B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12971893) Ensembl
MGI		 PMID:12971893 GO_REF:0000107 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16342201) Ensembl
MGI		 PMID:16342201 GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
optic nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA2 potassium voltage-gated channel subfamily A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15102918) Ensembl
MGI		 PMID:15102918 GO_REF:0000107 NCBI chr 1:113,187,158...113,256,260
Ensembl chr 1:127,090,829...127,092,328 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 involved_in ISO (MGI:5009386|PMID:18083586) UniProt PMID:18083586 MGI:5009386 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
trigeminal nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRP1 neuropilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15814794) Ensembl
MGI		 PMID:15814794 GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G PLXNA4 plexin A4 acts_upstream_of_or_within ISO (PMID:15814794) MGI PMID:15814794 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
trigeminal nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G PLXNA3 plexin A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,900,029...143,915,391
Ensembl chr  X:153,772,700...153,786,167 		JBrowse link
G PLXNA4 plexin A4 involved_in ISO (MGI:3822054|PMID:18804103) ParkinsonsUK-UCL PMID:18804103 MGI:3822054 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
G SEMA3A semaphorin 3A involved_in ISO (MGI:3822054|PMID:18804103) ParkinsonsUK-UCL PMID:18804103 MGI:3822054 NCBI chr 7:75,929,699...76,484,246
Ensembl chr 7:89,590,359...90,004,122 		JBrowse link
G SEMA3F semaphorin 3F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:50,083,733...50,117,518
Ensembl chr 3:51,318,089...51,351,958 		JBrowse link
trochlear nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHOX2A paired like homeobox 2A involved_in ISO (MGI:1098916|PMID:9374403) BHF-UCL PMID:9374403 MGI:1098916 NCBI chr11:67,317,747...67,322,850 JBrowse link
vagus nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLXNA4 plexin A4 acts_upstream_of_or_within ISO (PMID:15814794) MGI PMID:15814794 NCBI chr 7:124,097,028...124,621,504
Ensembl chr 7:136,643,657...136,992,405 		JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:20939858) MGI PMID:20939858 NCBI chr22:2,521,080...2,541,267 JBrowse link
vestibulocochlear nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP8B1 ATPase phospholipid transporting 8B1 involved_in ISO (MGI:3849653|PMID:19478059) UniProt PMID:19478059 MGI:3849653 NCBI chr18:51,035,483...51,187,461
Ensembl chr18:54,370,447...54,522,196 		JBrowse link
G DCANP1 dendritic cell associated nuclear protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,838,844...130,839,588
Ensembl chr 5:136,979,950...136,980,694 		JBrowse link
G NEUROG1 neurogenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,922,727...130,924,403
Ensembl chr 5:137,064,339...137,065,052 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G TIFAB TIFA inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,836,697...130,846,050
Ensembl chr 5:136,983,040...136,983,525 		JBrowse link
vestibulocochlear nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G NRP2 neuropilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:92,911,721...93,027,032
Ensembl chr2B:211,042,324...211,157,547 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    developmental process 6563
      anatomical structure morphogenesis 2851
        cranial nerve morphogenesis 32
          abducens nerve morphogenesis + 2
          accessory nerve morphogenesis + 0
          cranial ganglion morphogenesis + 0
          cranial nerve formation + 11
          cranial nerve structural organization + 13
          facial nerve morphogenesis + 12
          glossopharyngeal nerve morphogenesis + 4
          hypoglossal nerve morphogenesis + 1
          oculomotor nerve morphogenesis + 2
          olfactory nerve morphogenesis + 3
          optic nerve morphogenesis + 6
          trigeminal nerve morphogenesis + 5
          trochlear nerve morphogenesis + 1
          vagus nerve morphogenesis + 2
          vestibulocochlear nerve morphogenesis + 7
Path 2
Term Annotations click to browse term
  biological_process 16440
    developmental process 6563
      anatomical structure development 6172
        multicellular organism development 4975
          system development 4324
            nervous system development 2702
              nerve development 121
                cranial nerve development 77
                  cranial nerve morphogenesis 32
                    abducens nerve morphogenesis + 2
                    accessory nerve morphogenesis + 0
                    cranial ganglion morphogenesis + 0
                    cranial nerve formation + 11
                    cranial nerve structural organization + 13
                    facial nerve morphogenesis + 12
                    glossopharyngeal nerve morphogenesis + 4
                    hypoglossal nerve morphogenesis + 1
                    oculomotor nerve morphogenesis + 2
                    olfactory nerve morphogenesis + 3
                    optic nerve morphogenesis + 6
                    trigeminal nerve morphogenesis + 5
                    trochlear nerve morphogenesis + 1
                    vagus nerve morphogenesis + 2
                    vestibulocochlear nerve morphogenesis + 7
paths to the root