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ONTOLOGY REPORT - ANNOTATIONS


Term:trigeminal nerve development
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Accession:GO:0021559 term browser browse the term
Definition:The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
Synonyms:exact_synonym: cranial nerve 5 development;   cranial nerve V development
 related_synonym: CN V development



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trigeminal nerve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drgx dorsal root ganglia homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2182636 (MGI:2670488|PMID:12917357)
Ensembl
RGD
PMID:12917357 GO_REF:0000107 MGI:2670488 NCBI chr16:7,854,849...7,884,404
Ensembl chr16:7,854,849...7,900,600
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO (MGI:3815381|PMID:18849985) RGD PMID:18849985 MGI:3815381 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571
JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:4367920|PMID:19877281)
Ensembl
RGD
PMID:19877281 GO_REF:0000107 MGI:4367920 NCBI chr15:81,255,566...81,260,057
Ensembl chr15:81,257,781...81,259,728
JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:80519|PMID:8622766)
UniProt
RGD
PMID:8622766 GO_REF:0000024 MGI:80519 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592
JBrowse link
trigeminal nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:1857853 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Plxna4 plexin A4 acts_upstream_of_or_within ISO MGI:3578655 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
JBrowse link
trigeminal nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 involved_in ISO (MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:3822054 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Plxna3 plexin A3 involved_in ISO (MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:3822054 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Plxna4 plexin A4 involved_in ISO (MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:3822054 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
JBrowse link
G Sema3a semaphorin 3A involved_in ISO (MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:3822054 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Sema3f semaphorin 3F involved_in ISO (MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:3822054 NCBI chr 8:108,357,629...108,387,083
Ensembl chr 8:108,357,629...108,387,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    developmental process 6778
      anatomical structure development 6203
        nerve development 96
          cranial nerve development 59
            trigeminal nerve development 11
              trigeminal nerve maturation + 0
              trigeminal nerve morphogenesis + 5
Path 2
Term Annotations click to browse term
  biological_process 19504
    developmental process 6778
      anatomical structure development 6203
        multicellular organism development 5642
          system development 5310
            nervous system development 2734
              nerve development 96
                cranial nerve development 59
                  trigeminal nerve development 11
                    trigeminal nerve maturation + 0
                    trigeminal nerve morphogenesis + 5
paths to the root