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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary morphogenesis
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Accession:GO:0021555 term browser browse the term
Definition:The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms:exact_synonym: MHB morphogenesis;   isthmus morphogenesis



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midbrain-hindbrain boundary morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbx2 gastrulation brain homeobox 2 acts_upstream_of_or_within ISO MGI:1857634 (MGI:3624192|PMID:16651541) RGD PMID:16651541 MGI:3624192 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104877 (MGI:2149154|PMID:11500373)
Ensembl
RGD
PMID:11500373 GO_REF:0000107 MGI:2149154 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes3 hes family bHLH transcription factor 3 acts_upstream_of_or_within ISO MGI:104853 (MGI:2149134|PMID:11522634) RGD PMID:11522634 MGI:2149134 NCBI chr 5:162,793,611...162,799,578
Ensembl chr 5:162,794,367...162,796,261
JBrowse link
G Kdm2b lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    developmental process 7026
      anatomical structure morphogenesis 2998
        embryonic morphogenesis 705
          midbrain-hindbrain boundary morphogenesis 4
            midbrain-hindbrain boundary structural organization 0
Path 2
Term Annotations click to browse term
  biological_process 20292
    developmental process 7026
      anatomical structure development 6534
        multicellular organism development 5258
          embryo development 1363
            embryo development ending in birth or egg hatching 889
              chordate embryonic development 872
                neural tube development 198
                  neural tube patterning 44
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary morphogenesis 4
                          midbrain-hindbrain boundary structural organization 0
paths to the root