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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary initiation
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Accession:GO:0021547 term browser browse the term
Definition:The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms:exact_synonym: MHB biosynthesis;   MHB formation;   midbrain-hindbrain boundary biosynthesis;   midbrain-hindbrain boundary formation
 related_synonym: isthmus biosynthesis;   isthmus formation


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midbrain-hindbrain boundary initiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ssbp3 single stranded DNA binding protein 3 IEA
ISO
GO_REF:0000107
(MGI:3578570|PMID:15857913)
Ensembl
RGD
PMID:15857913 GO_REF:0000107 MGI:3578570 NCBI chr 5:126,511,339...126,649,830
Ensembl chr 5:126,511,350...126,648,661
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    developmental process 6848
      anatomical structure formation involved in morphogenesis 1222
        midbrain-hindbrain boundary initiation 1
Path 2
Term Annotations click to browse term
  biological_process 20078
    developmental process 6848
      anatomical structure development 6308
        multicellular organism development 5783
          embryo development 1312
            embryo development ending in birth or egg hatching 863
              chordate embryonic development 847
                neural tube development 199
                  neural tube patterning 50
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary initiation 1
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