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ONTOLOGY REPORT - ANNOTATIONS

Term:neural tube patterning
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Accession:GO:0021532 term browser browse the term
Definition:The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.


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neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl13b ADP-ribosylation factor like GTPase 13B involved_in ISO (MGI:5444047|PMID:23014696) RGD PMID:23014696 MGI:5444047 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197 		JBrowse link
G Dzip1l DAZ interacting zinc finger protein 1-like acts_upstream_of_or_within ISO MGI:2442827 (MGI:6149643|PMID:29487109) RGD PMID:29487109 MGI:6149643 NCBI chr 8:100,188,414...100,229,077
Ensembl chr 8:100,194,999...100,228,988 		JBrowse link
G Ift140 intraflagellar transport 140 acts_upstream_of_or_within ISO MGI:4458412 (MGI:5635784|PMID:24009529) RGD PMID:24009529 MGI:5635784 NCBI chr10:14,032,665...14,121,682
Ensembl chr10:14,032,648...14,120,433 		JBrowse link
G Ptch1 patched 1 involved_in ISO (PMID:8681379) RGD PMID:8681379 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (MGI:3715393|PMID:17553904) RGD PMID:17553904 MGI:3715393 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:1919757 (MGI:6149643|PMID:29487109) RGD PMID:29487109 MGI:6149643 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Tmem107 transmembrane protein 107 involved_in ISO (MGI:5432629|PMID:22698544) RGD PMID:22698544 MGI:5432629 NCBI chr10:53,772,153...53,774,685
Ensembl chr10:53,771,784...53,774,676 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3046395|PMID:15218525)		 Ensembl
RGD		 PMID:15218525 GO_REF:0000107 MGI:3046395 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO MGI:107689|MGI:3042750|MGI:3775614|MGI:95728 (MGI:3774974|PMID:18003640), (MGI:3806189|PMID:18590716) RGD PMID:18003640 PMID:18590716 MGI:3774974 MGI:3806189 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1347476 (MGI:5486225|PMID:23383217)		 Ensembl
RGD		 PMID:23383217 GO_REF:0000107 MGI:5486225 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472|MGI:95841 (MGI:3806189|PMID:18590716), (MGI:5486225|PMID:23383217), (MGI:894511|PMID:9226455) RGD PMID:9226455 PMID:18590716 PMID:23383217 MGI:3806189 MGI:5486225 MGI:894511 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:3711070|MGI:98297 (MGI:3710451|PMID:17504941), (MGI:3710452|PMID:17504940) RGD PMID:17504940 PMID:17504941 MGI:3710451 MGI:3710452 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:3806189|PMID:18590716), (MGI:3841503|PMID:19286674), (MGI:894564|PMID:9247260) RGD PMID:9247260 PMID:18590716 PMID:19286674 MGI:3806189 MGI:3841503 MGI:894564 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gsc goosecoid homeobox acts_upstream_of_or_within ISO MGI:1347476 (MGI:894511|PMID:9226455) RGD PMID:9226455 MGI:894511 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
G Kif3a kinesin family member 3a acts_upstream_of_or_within
involved_in		 ISO MGI:1341070|MGI:1861960|MGI:95728 (MGI:3806189|PMID:18590716), (MGI:3841503|PMID:19286674)
(MGI:4888042|PMID:21209331)		 RGD PMID:18590716 PMID:19286674 PMID:21209331 MGI:3806189 MGI:3841503 MGI:4888042 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within ISO (MGI:3806189|PMID:18590716) RGD PMID:18590716 MGI:3806189 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Pax7 paired box 7 acts_upstream_of_or_within ISO (MGI:3806189|PMID:18590716) RGD PMID:18590716 MGI:3806189 NCBI chr 5:151,996,368...152,098,023
Ensembl chr 5:151,999,092...152,097,979 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:1347695|PMID:10557208) RGD PMID:10557208 MGI:1347695 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:1347695|PMID:10557208) RGD PMID:10557208 MGI:1347695 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1095757|PMID:9262482) RGD PMID:9262482 MGI:1095757 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Rab23 RAB23, member RAS oncogene family involved_in ISO (MGI:69552|PMID:7720556) RGD PMID:7720556 MGI:69552 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927 		JBrowse link
G Rnf220 ring finger protein 220 acts_upstream_of_or_within ISO MGI:6393918 (MGI:6220747|PMID:30177510) RGD PMID:30177510 MGI:6220747 NCBI chr 5:130,739,173...130,961,386
Ensembl chr 5:130,739,183...130,961,418 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95655 (MGI:3710017|PMID:17442700), (MGI:3710451|PMID:17504941), (MGI:3806189|PMID:18590716)
(MGI:4888042|PMID:21209331)		 Ensembl
RGD		 PMID:17442700 PMID:17504941 PMID:18590716 PMID:21209331 GO_REF:0000107 MGI:3710017 MGI:3710451 MGI:3806189 MGI:4888042 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176255 (MGI:3806189|PMID:18590716)		 Ensembl
RGD		 PMID:18590716 GO_REF:0000107 MGI:3806189 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (MGI:3610767|PMID:16357211) RGD PMID:16357211 MGI:3610767 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:1857489 (MGI:64780|PMID:8299937) RGD PMID:8299937 MGI:64780 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
forebrain-midbrain boundary formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856155|MGI:1856158 (MGI:892757|PMID:9169845)		 Ensembl
RGD		 PMID:9169845 GO_REF:0000107 MGI:892757 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
midbrain-hindbrain boundary development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G En1 engrailed homeobox 1 acts_upstream_of_or_within ISO MGI:1857163 (MGI:3525936|PMID:15607945) RGD PMID:15607945 MGI:3525936 NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:2150347 (MGI:3720541|PMID:17601531) RGD PMID:17601531 MGI:3720541 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gbx2 gastrulation brain homeobox 2 acts_upstream_of_or_within ISO MGI:1857634 (MGI:3624192|PMID:16651541) RGD PMID:16651541 MGI:3624192 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:1891551|PMID:11029008), (MGI:4413372|PMID:19795512) RGD PMID:11029008 PMID:19795512 MGI:1891551 MGI:4413372 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO MGI:1857490 (MGI:59176|PMID:2205396) RGD PMID:2205396 MGI:59176 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
midbrain-hindbrain boundary initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ssbp3 single stranded DNA binding protein 3 involved_in ISO (MGI:3578570|PMID:15857913) RGD PMID:15857913 MGI:3578570 NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992 		JBrowse link
midbrain-hindbrain boundary maturation during brain development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO MGI:1856382 (MGI:76584|PMID:8555108) RGD PMID:8555108 MGI:76584 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
midbrain-hindbrain boundary morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbx2 gastrulation brain homeobox 2 acts_upstream_of_or_within ISO MGI:1857634 (MGI:3624192|PMID:16651541) RGD PMID:16651541 MGI:3624192 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104877 (MGI:2149154|PMID:11500373)		 Ensembl
RGD		 PMID:11500373 GO_REF:0000107 MGI:2149154 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes3 hes family bHLH transcription factor 3 acts_upstream_of_or_within ISO MGI:104853 (MGI:2149134|PMID:11522634) RGD PMID:11522634 MGI:2149134 NCBI chr 5:162,793,611...162,799,578
Ensembl chr 5:162,794,367...162,796,261 		JBrowse link
G Kdm2b lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355 		JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:108075|MGI:99833 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Gpr161 G protein-coupled receptor 161 involved_in ISO (MGI:5468365|PMID:23332756) RGD PMID:23332756 MGI:5468365 NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within ISO MGI:97760 (MGI:5308523|PMID:22007132) RGD PMID:22007132 MGI:5308523 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within ISO MGI:97592 (MGI:5308523|PMID:22007132) RGD PMID:22007132 MGI:5308523 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (MGI:7262356|PMID:35353806) RGD PMID:35353806 MGI:7262356 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3844764|PMID:19334287) RGD PMID:19334287 MGI:3844764 NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gorab golgin, RAB6-interacting acts_upstream_of_or_within ISO (MGI:5766823|PMID:26967474) RGD PMID:26967474 MGI:5766823 NCBI chr13:75,745,678...75,762,307
Ensembl chr13:75,745,680...75,762,298 		JBrowse link
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (MGI:6107986|PMID:29038301) RGD PMID:29038301 MGI:6107986 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4887578 (MGI:4868517|PMID:21045211)		 Ensembl
RGD		 PMID:21045211 GO_REF:0000107 MGI:4868517 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
rostrocaudal neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO (PMID:20093472) RGD PMID:20093472 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO MGI:1857632 (MGI:82985|PMID:8887324) RGD PMID:8887324 MGI:82985 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO MGI:2179440 (MGI:4421275|PMID:19913509) RGD PMID:19913509 MGI:4421275 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2442827|MGI:95729 (MGI:3709667|PMID:17395647), (MGI:4439200|PMID:20159594) RGD PMID:17395647 PMID:20159594 MGI:3709667 MGI:4439200 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2442827|MGI:95728 (MGI:3709667|PMID:17395647), (MGI:4439200|PMID:20159594) RGD PMID:17395647 PMID:20159594 MGI:3709667 MGI:4439200 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within ISO MGI:2443231 (MGI:5428054|PMID:22689656) RGD PMID:22689656 MGI:5428054 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:3664273 (MGI:3841513|PMID:19223390) RGD PMID:19223390 MGI:3841513 NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO MGI:1932386|MGI:5315748 (MGI:5428054|PMID:22689656) RGD PMID:22689656 MGI:5428054 NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288 		JBrowse link
zona limitans intrathalamica formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule IDA RGD PMID:25281935 RGD:12832757 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    multicellular organismal process 9178
      pattern specification process 499
        regionalization 454
          neural tube patterning 52
            dorsal/ventral neural tube patterning + 34
            rostrocaudal neural tube patterning + 14
Path 2
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  biological_process 19746
    developmental process 6931
      anatomical structure development 6386
        multicellular organism development 5165
          embryo development 1359
            embryo development ending in birth or egg hatching 882
              chordate embryonic development 865
                neural tube development 202
                  neural tube patterning 52
                    dorsal/ventral neural tube patterning + 34
                    rostrocaudal neural tube patterning + 14
paths to the root