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ONTOLOGY REPORT - ANNOTATIONS


Term:somatic motor neuron differentiation
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Accession:GO:0021523 term browser browse the term
Definition:The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


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somatic motor neuron differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln8 CLN8, transmembrane ER and ERGIC protein ISO (MGI:4849309|PMID:21052544) RGD PMID:21052544 MGI:4849309 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Phox2a paired-like homeobox 2a IEA
ISO
GO_REF:0000107
MGI:3521825 (MGI:3761765|PMID:16319924)
Ensembl
RGD
PMID:16319924 GO_REF:0000107, MGI:3761765 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Tctn1 tectonic family member 1 ISO MGI:3716885 (MGI:3610767|PMID:16357211) RGD PMID:16357211 MGI:3610767 NCBI chr12:39,790,948...39,828,215
Ensembl chr12:39,790,965...39,824,064
JBrowse link
medial motor column neuron differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 ISO MGI:101776 (MGI:1316601|PMID:9865699) RGD PMID:9865699 MGI:1316601 NCBI chr 3:3,653,861...3,662,509
Ensembl chr 3:3,654,755...3,661,810
JBrowse link
G Lhx4 LIM homeobox 4 ISO MGI:102673 (MGI:1316601|PMID:9865699) RGD PMID:9865699 MGI:1316601 NCBI chr13:73,348,874...73,400,416
Ensembl chr13:73,348,842...73,400,416
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        ventral spinal cord development 57
          spinal cord motor neuron differentiation 41
            somatic motor neuron differentiation 5
              lateral motor column neuron differentiation 0
              medial motor column neuron differentiation 2
              somatic motor neuron fate commitment + 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              neurogenesis 1936
                generation of neurons 1780
                  neuron differentiation 1614
                    central nervous system neuron differentiation 240
                      spinal cord motor neuron differentiation 41
                        somatic motor neuron differentiation 5
                          lateral motor column neuron differentiation 0
                          medial motor column neuron differentiation 2
                          somatic motor neuron fate commitment + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.