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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord motor neuron differentiation
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Accession:GO:0021522 term browser browse the term
Definition:The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.



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spinal cord motor neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Abt1 activator of basal transcription 1 acts_upstream_of_or_within ISO MGI:99954 (MGI:3845694|PMID:19299493) RGD PMID:19299493 MGI:3845694 NCBI chr17:41,699,151...41,701,253
Ensembl chr17:41,699,147...41,701,259
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:1856211 (MGI:3794823|PMID:17156092) RGD PMID:17156092 MGI:3794823 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO MGI:1856959 (MGI:3709684|PMID:2061715) RGD PMID:2061715 MGI:3709684 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 acts_upstream_of_or_within ISO MGI:105373|MGI:95729|MGI:98297 (MGI:5441704|PMID:21552265) RGD PMID:21552265 MGI:5441704 NCBI chr 8:4,189,257...4,412,183
Ensembl chr 8:4,189,257...4,412,183
JBrowse link
G Gbx1 gastrulation brain homeobox 1 acts_upstream_of_or_within ISO (MGI:5491108|PMID:23418536) RGD PMID:23418536 MGI:5491108 NCBI chr 4:10,645,957...10,672,486
Ensembl chr 4:10,645,957...10,672,486
JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 acts_upstream_of_or_within ISO MGI:5302017 (MGI:5299268|PMID:21943603) RGD PMID:21943603 MGI:5299268 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO MGI:4126459 (MGI:4366664|PMID:19744960) RGD PMID:19744960 MGI:4366664 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:5441704|PMID:21552265) RGD PMID:21552265 MGI:5441704 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:107736 (MGI:5441704|PMID:21552265) RGD PMID:21552265 MGI:5441704 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2682066 (MGI:5441704|PMID:21552265)
GO_REF:0000107
RGD
Ensembl
PMID:21552265 GO_REF:0000107 MGI:5441704 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 acts_upstream_of_or_within ISO MGI:1857648 (MGI:3845694|PMID:19299493) RGD PMID:19299493 MGI:3845694 NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:2182246 (MGI:78615|PMID:8565076) RGD PMID:8565076 MGI:78615 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Lbx1 ladybird homeobox 1 acts_upstream_of_or_within ISO MGI:2149955 (MGI:3531376|PMID:15769945) RGD PMID:15769945 MGI:3531376 NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690
JBrowse link
G Lmo4 LIM domain only 4 acts_upstream_of_or_within ISO (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880
JBrowse link
G Mdga2 MAM domain containing glycosylphosphatidylinositol anchor 2 involved_in IEP PMID:15019943 HGNC-UCL PMID:15019943 RGD:8554528 NCBI chr 6:84,746,422...85,608,640
Ensembl chr 6:84,761,941...85,608,126
JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3619438|MGI:3629917|MGI:3629918|MGI:3790968 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir18a microRNA 18a acts_upstream_of_or_within ISO MGI:2676868|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3619438|MGI:3629917|MGI:3629918 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir19a microRNA 19a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629918 (MGI:5139953|PMID:21741442) RGD PMID:21741442 MGI:5139953 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir20a microRNA 20a acts_upstream_of_or_within ISO MGI:2676844|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir92a1 microRNA 92a-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO MGI:3828165 (MGI:5433806|PMID:21554501) RGD PMID:21554501 MGI:5433806 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:1334824|PMID:10217145) RGD PMID:10217145 MGI:1334824 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO MGI:3774124 (MGI:5140688|PMID:21338882) RGD PMID:21338882 MGI:5140688 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 acts_upstream_of_or_within ISO MGI:104867|MGI:3573868 (MGI:3530702|PMID:15674731), (MGI:3531376|PMID:15769945) RGD PMID:15674731 PMID:15769945 MGI:3530702 MGI:3531376 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:107736 (MGI:5441704|PMID:21552265) RGD PMID:21552265 MGI:5441704 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Scyl1 SCY1 like pseudokinase 1 acts_upstream_of_or_within ISO MGI:1921385|MGI:5469960 (MGI:6161057|PMID:29437892) RGD PMID:29437892 MGI:6161057 NCBI chr 1:203,045,776...203,059,550
Ensembl chr 1:203,045,741...203,059,533
JBrowse link
G Scyl3 SCY1 like pseudokinase 3 acts_upstream_of_or_within ISO MGI:1931787 (MGI:6161057|PMID:29437892) RGD PMID:29437892 MGI:6161057 NCBI chr13:76,278,428...76,303,038
Ensembl chr13:76,278,428...76,301,716
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:107736 (MGI:5441704|PMID:21552265)
Ensembl
RGD
PMID:21552265 GO_REF:0000107 MGI:5441704 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:4838379|PMID:20646169) RGD PMID:20646169 MGI:4838379 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
medial motor column neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:101776 (MGI:1316601|PMID:9865699) RGD PMID:9865699 MGI:1316601 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Lhx4 LIM homeobox 4 acts_upstream_of_or_within ISO MGI:102673 (MGI:1316601|PMID:9865699) RGD PMID:9865699 MGI:1316601 NCBI chr13:67,873,618...67,927,003
Ensembl chr13:67,877,109...67,927,003
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
somatic motor neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO (MGI:4849309|PMID:21052544) RGD PMID:21052544 MGI:4849309 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3521825 (MGI:3761765|PMID:16319924)
Ensembl
RGD
PMID:16319924 GO_REF:0000107 MGI:3761765 NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (MGI:3610767|PMID:16357211) RGD PMID:16357211 MGI:3610767 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267
JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeo box C10 acts_upstream_of_or_within ISO MGI:96202 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
JBrowse link
G Hoxd10 homeo box D10 acts_upstream_of_or_within ISO MGI:96192 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 3:59,594,516...59,597,725
Ensembl chr 3:59,594,516...59,597,725
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:102673 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:102673 (MGI:4356383|PMID:19666821)
Ensembl
RGD
PMID:19666821 GO_REF:0000107 MGI:4356383 NCBI chr 8:55,923,805...55,928,790
Ensembl chr 8:55,923,805...55,928,790
JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:101791|MGI:109156 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2182358|MGI:2182361|MGI:2182363 (MGI:1344237|PMID:10482234)
RGD PMID:10482234 PMID:21873635 MGI:1344237, RGD:13792537 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 acts_upstream_of_or_within ISO MGI:3573868 (MGI:3531376|PMID:15769945) RGD PMID:15769945 MGI:3531376 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149
JBrowse link
visceral motor neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:109156 (MGI:3041365|PMID:14766174) RGD PMID:14766174 MGI:3041365 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:101791|MGI:3046260 (MGI:3041365|PMID:14766174)
Ensembl
RGD
PMID:14766174 GO_REF:0000107 MGI:3041365 NCBI chr 8:55,923,805...55,928,790
Ensembl chr 8:55,923,805...55,928,790
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        ventral spinal cord development 59
          spinal cord motor neuron differentiation 42
            lateral motor column neuron differentiation 0
            somatic motor neuron differentiation + 5
            spinal cord motor neuron cell fate specification + 10
            visceral motor neuron differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        multicellular organism development 5224
          system development 4484
            nervous system development 2804
              neurogenesis 2011
                generation of neurons 1743
                  neuron differentiation 1667
                    central nervous system neuron differentiation 225
                      spinal cord motor neuron differentiation 42
                        lateral motor column neuron differentiation 0
                        somatic motor neuron differentiation + 5
                        spinal cord motor neuron cell fate specification + 10
                        visceral motor neuron differentiation 3
paths to the root