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ONTOLOGY REPORT - ANNOTATIONS

Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning


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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:20,551,528...20,561,132
Ensembl chr16:20,551,877...20,561,134 		JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within IMP (PMID:21761479) MGI PMID:21761479 NCBI chr 7:44,545,517...44,552,053
Ensembl chr 7:44,545,503...44,552,055 		JBrowse link
G Gli2 GLI-Kruppel family member GLI2 acts_upstream_of_or_within IGI
IMP		 (PMID:16364285)
(PMID:15215207)
(PMID:11748151)		 MGI PMID:11748151 PMID:15215207 PMID:16364285 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 acts_upstream_of_or_within IGI (PMID:16364285)
(PMID:15215207)		 MGI PMID:15215207 PMID:16364285 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in IMP (MGI:4888042|PMID:21209331) BHF-UCL PMID:21209331 MGI:4888042 NCBI chr 6:115,830,340...115,903,660
Ensembl chr 6:115,830,431...115,903,660 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within IMP (PMID:21761479) MGI PMID:21761479 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Intu inturned planar cell polarity protein acts_upstream_of_or_within IMP (PMID:21761479) MGI PMID:21761479 NCBI chr 3:40,585,559...40,659,206
Ensembl chr 3:40,585,435...40,659,204 		JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within IGI
IMP		 (PMID:16364285)
(PMID:15755804), (PMID:16364285)
(PMID:14603322)		 MGI PMID:14603322 PMID:15755804 PMID:16364285 NCBI chr 1:33,758,991...33,781,642
Ensembl chr 1:33,758,968...33,781,645 		JBrowse link
G Rfx4 regulatory factor X, 4 (influences HLA class II expression) acts_upstream_of_or_within IC (MGI:5430880|PMID:19887680) GOC PMID:19887680 MGI:5430880 NCBI chr10:84,591,895...84,742,402
Ensembl chr10:84,591,926...84,742,402 		JBrowse link
G Shh sonic hedgehog acts_upstream_of_or_within ISO
IMP		 (PMID:11748151) MGI PMID:11748151 GO_REF:0000008 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in IMP (MGI:4888042|PMID:21209331) BHF-UCL PMID:21209331 MGI:4888042 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within IMP (PMID:16459298) MGI PMID:16459298 NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI-Kruppel family member GLI2 acts_upstream_of_or_within IGI (PMID:15215207) MGI PMID:15215207 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 acts_upstream_of_or_within IGI (PMID:15215207) MGI PMID:15215207 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within IMP (PMID:19684112) MGI PMID:19684112 NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI-Kruppel family member GLI2 acts_upstream_of_or_within IGI (PMID:15215207) MGI PMID:15215207 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 acts_upstream_of_or_within IGI (PMID:15215207) MGI PMID:15215207 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within IMP (PMID:19684112) MGI PMID:19684112 NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243 		JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in IMP (MGI:3587461|PMID:16020526) UniProt PMID:16020526 MGI:3587461 NCBI chr10:87,326,681...87,329,522
Ensembl chr10:87,326,681...87,329,522 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G Foxn4 forkhead box N4 involved_in IMP (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) UniProt PMID:16020526 PMID:17728344 MGI:3587461 MGI:3765356 NCBI chr 5:114,392,225...114,412,486
Ensembl chr 5:114,392,225...114,411,868 		JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within IMP (PMID:10217145) MGI PMID:10217145 NCBI chr 2:146,967,909...147,037,270
Ensembl chr 2:147,019,466...147,036,163 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within IMP (PMID:11239429) MGI PMID:11239429 NCBI chr 7:49,281,247...49,286,583
Ensembl chr 7:49,281,247...49,286,597 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within IMP (PMID:22932389) MGI PMID:22932389 NCBI chr19:25,587,609...25,601,285
Ensembl chr19:25,587,665...25,601,285 		JBrowse link
G Lhx3 LIM homeobox protein 3 acts_upstream_of_or_within IDA (PMID:19666821) MGI PMID:19666821 NCBI chr 2:26,090,224...26,098,261
Ensembl chr 2:26,090,224...26,098,301 		JBrowse link
G Shh sonic hedgehog acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Sox1 SRY (sex determining region Y)-box 1 acts_upstream_of_or_within IMP (PMID:20844123) MGI PMID:20844123 NCBI chr 8:12,445,519...12,449,555
Ensembl chr 8:12,445,295...12,450,126 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    multicellular organismal process 8908
      pattern specification process 496
        regionalization 451
          dorsal/ventral pattern formation 100
            spinal cord dorsal/ventral patterning 20
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 0
              retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 3
              ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 28573
    developmental process 7369
      anatomical structure development 6841
        multicellular organism development 5433
          system development 4660
            nervous system development 2850
              central nervous system development 1220
                spinal cord development 142
                  spinal cord patterning 22
                    spinal cord dorsal/ventral patterning 20
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 0
                      retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 3
                      ventral spinal cord interneuron fate commitment + 12
paths to the root