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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning



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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (MGI:5052192|PMID:21761479) RGD PMID:21761479 MGI:5052192 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509|MGI:2158472|MGI:95729|MGI:99833 (MGI:2154468|PMID:11748151), (MGI:3051712|PMID:15215207), (MGI:3612806|PMID:16364285) RGD PMID:11748151 PMID:15215207 PMID:16364285 MGI:2154468 MGI:3051712 MGI:3612806 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728|MGI:99833 (MGI:3051712|PMID:15215207), (MGI:3612806|PMID:16364285) RGD PMID:15215207 PMID:16364285 MGI:3051712 MGI:3612806 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153 (MGI:5052192|PMID:21761479) RGD PMID:21761479 MGI:5052192 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (MGI:5052192|PMID:21761479)
Ensembl
RGD
PMID:21761479 GO_REF:0000107 MGI:5052192 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2137533|MGI:2682064|MGI:95728|MGI:95729 (MGI:2679893|PMID:14603322), (MGI:3577662|PMID:15755804), (MGI:3612806|PMID:16364285) RGD PMID:14603322 PMID:15755804 PMID:16364285 MGI:2679893 MGI:3577662 MGI:3612806 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
IDA
ISO
GO_REF:0000107
PMID:9230312
MGI:1857796 (MGI:2154468|PMID:11748151)
Ensembl
RGD
PMID:11748151 PMID:9230312 GO_REF:0000107 MGI:2154468, RGD:8553789 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:3619046 (MGI:3616741|PMID:16459298) RGD PMID:16459298 MGI:3616741 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
BMP signaling pathway involved in spinal cord dorsal/ventral patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin involved_in IEA
ISO
GO_REF:0000107
(PMID:11472837)
Ensembl
RGD
PMID:11472837 GO_REF:0000107 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ift122 intraflagellar transport 122 involved_in ISO (MGI:4888042|PMID:21209331) RGD PMID:21209331 MGI:4888042 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458
JBrowse link
G Rfx4 regulatory factor X4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3799278 (MGI:5430880|PMID:19887680)
RGD PMID:19887680 PMID:21873635 MGI:5430880, RGD:13792537 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176255 (MGI:3841503|PMID:19286674)
(MGI:4888042|PMID:21209331)
Ensembl
RGD
PMID:19286674 PMID:21209331 GO_REF:0000107 MGI:3841503 MGI:4888042 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3587461|PMID:16020526)
UniProt
RGD
PMID:16020526 GO_REF:0000024 MGI:3587461 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO UniProtKB:Q8K3Q3 (PMID:17728344) RGD PMID:17728344 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Foxn4 forkhead box N4 involved_in ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) RGD PMID:16020526 PMID:17728344 MGI:3587461 MGI:3765356 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:1334824|PMID:10217145) RGD PMID:10217145 MGI:1334824 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within ISO MGI:2182329 (MGI:2136554|PMID:11239429) RGD PMID:11239429 MGI:2136554 NCBI chr 1:99,349,608...99,354,038
Ensembl chr 1:99,349,608...99,354,038
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO MGI:4420993 (MGI:5435948|PMID:22932389) RGD PMID:22932389 MGI:5435948 NCBI chr 1:223,244,340...223,264,254
Ensembl chr 1:223,248,747...223,262,530
JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:3653406 (MGI:4834949|PMID:20844123) RGD PMID:20844123 MGI:4834949 NCBI chr16:77,134,795...77,139,628
Ensembl chr16:77,137,584...77,138,762
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    multicellular organismal process 9052
      pattern specification process 499
        regionalization 390
          spinal cord patterning 23
            spinal cord dorsal/ventral patterning 21
              BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
              retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 7
              ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            nervous system development 2747
              central nervous system development 1281
                spinal cord development 143
                  spinal cord patterning 23
                    spinal cord dorsal/ventral patterning 21
                      BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
                      retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 7
                      ventral spinal cord interneuron fate commitment + 12
paths to the root