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Term:heme binding
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Accession:GO:0020037 term browser browse the term
Definition:Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
Synonyms:exact_synonym: haem binding

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heme binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 (Langereis blood group) enables ISO (PMID:17006453), (PMID:33007128) UniProt PMID:17006453 PMID:33007128 NCBI chr2B:106,467,345...106,476,614
Ensembl chr2B:225,058,771...225,067,626
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor enables ISO (PMID:11877257) UniProt PMID:11877257 NCBI chr 9:85,157,680...85,176,253
Ensembl chr 9:113,525,835...113,543,422
JBrowse link
G CAT catalase enables ISO (PMID:10656833), (PMID:11134921) UniProt PMID:10656833 PMID:11134921 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CBS cystathionine beta-synthase enables ISO (PMID:18776696)
(PMID:24515102), (PMID:7929220)
UniProt PMID:7929220 PMID:18776696 PMID:24515102 NCBI chr21:29,361,519...29,385,610 JBrowse link
G CYGB cytoglobin ISO RGD PMID:11320098 RGD:68672 NCBI chr17:70,475,651...70,485,987
Ensembl chr17:76,167,947...76,179,412
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 enables ISO (PMID:21636783) UniProt PMID:21636783 NCBI chr15:53,280,110...53,310,868
Ensembl chr15:72,901,286...72,931,164
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 enables ISO (PMID:22266943) UniProt PMID:22266943 NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 enables ISO (PMID:19129847) UniProt PMID:19129847 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 enables ISO (PMID:17311915) UniProt PMID:17311915 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 enables ISO (PMID:21147782) UniProt PMID:21147782 NCBI chr2A:38,087,863...38,096,529
Ensembl chr2A:38,851,000...38,859,824
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 enables ISO (PMID:9660774) UniProt PMID:9660774 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 enables ISO (PMID:20061448) UniProt PMID:20061448 NCBI chr19:38,003,083...38,028,980
Ensembl chr19:46,509,370...46,534,672
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 enables ISO (PMID:23118231) UniProt PMID:23118231 NCBI chr10:91,375,255...91,465,215
Ensembl chr10:94,884,472...94,970,065
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 enables ISO (PMID:18818195) UniProt PMID:18818195 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 enables ISO (PMID:18511070) UniProt PMID:18511070 NCBI chr11:14,960,651...14,989,083
Ensembl chr11:14,656,939...14,671,584
JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 enables ISO (PMID:18621681), (PMID:20667828), (PMID:23288837) UniProt PMID:18621681 PMID:20667828 PMID:23288837 NCBI chr14:80,309,698...80,352,181
Ensembl chr14:99,628,511...99,671,218
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 enables ISO (PMID:20149798) UniProt PMID:20149798 NCBI chr 7:84,110,130...84,132,870
Ensembl chr 7:97,708,806...97,729,824
JBrowse link
G DGCR8 DGCR8 microprocessor complex subunit enables ISO (PMID:24449907), (PMID:24910438) BHF-UCL PMID:24449907 PMID:24910438 NCBI chr22:2,841,041...2,872,325
Ensembl chr22:18,518,783...18,544,740
JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 enables ISO (MGI:3687787|PMID:10671563) UniProt PMID:10671563 MGI:3687787 NCBI chr 7:7,382,669...7,418,469
Ensembl chr 7:6,222,187...6,256,252
JBrowse link
G FECH ferrochelatase enables ISO (MGI:3620268|PMID:16503645) MGI PMID:16503645 MGI:3620268 NCBI chr18:50,934,520...50,977,132
Ensembl chr18:54,273,527...54,312,378
JBrowse link
G FLVCR2 FLVCR heme transporter 2 enables ISO (PMID:20823265) UniProt PMID:20823265 NCBI chr14:56,132,370...56,209,882 JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 ISO RGD PMID:11688978 RGD:1298936 NCBI chr 4:148,124,643...148,173,315
Ensembl chr 4:159,942,017...159,990,511
JBrowse link
G HEBP1 heme binding protein 1 enables ISO (MGI:1321349|PMID:9813049), (MGI:2445908|PMID:12413491), (MGI:3695782|PMID:16905545) MGI PMID:9813049 PMID:12413491 PMID:16905545 MGI:1321349 MGI:2445908 MGI:3695782 NCBI chr12:12,985,690...13,012,298
Ensembl chr12:13,385,684...13,416,059
JBrowse link
G HMOX1 heme oxygenase 1 enables ISO (PMID:17915953) RGD
PMID:12044160 PMID:17915953 RGD:730276 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HRG histidine rich glycoprotein enables ISO (PMID:678554) UniProt PMID:678554 NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539
JBrowse link
G JAK2 Janus kinase 2 enables ISO (PMID:21036157) UniProt PMID:21036157 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G LOC100972845 cytochrome b561 domain-containing protein 2 enables ISO (PMID:19734123)
UniProt PMID:17938141 PMID:19734123 PMID:19943161 MGI:6202479 MGI:6202493 NCBI chr 3:50,276,985...50,280,196
Ensembl chr 3:51,512,141...51,515,481
JBrowse link
G LOC100977441 cytochrome b5 type B enables ISO (PMID:20861021) UniProt PMID:20861021 NCBI chr16:49,801,900...49,843,698
Ensembl chr16:69,187,541...69,226,744
JBrowse link
G LOC100977566 cytochrome b5 reductase 4 ISO RGD PMID:11913972 RGD:632262 NCBI chr 6:81,756,292...81,864,365
Ensembl chr 6:85,030,058...85,130,948
JBrowse link
G LOC100982531 cytochrome b-245 heavy chain enables ISO (PMID:9774399) BHF-UCL PMID:9774399 NCBI chr  X:30,230,394...30,267,379
Ensembl chr  X:37,939,704...37,973,183
JBrowse link
G LOC100982890 cytochrome c-type heme lyase enables ISO (PMID:23150584) UniProt PMID:23150584 NCBI chr  X:3,741,316...3,753,115
Ensembl chr  X:11,031,638...11,044,055
JBrowse link
G LOC100986481 cytochrome c enables ISO (MGI:3652666|PMID:16757556) MGI PMID:16757556 MGI:3652666 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549
JBrowse link
G LOC100993876 neuferricin enables ISO (MGI:4441091|PMID:19968755) MGI PMID:19968755 MGI:4441091 NCBI chr17:4,197,524...4,212,030
Ensembl chr17:4,189,395...4,233,093
JBrowse link
G NOS1 nitric oxide synthase 1 enables ISO PMID:1383204 BHF-UCL PMID:1383204 RGD:8553334 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
G NOS2 nitric oxide synthase 2 enables ISO (MGI:3807769|PMID:9271491), (MGI:3807772|PMID:1383204) BHF-UCL PMID:1383204 PMID:9271491 MGI:3807769 MGI:3807772 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NOS3 nitric oxide synthase 3 enables ISO (PMID:7488039) BHF-UCL PMID:7488039 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233
JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 enables ISO (PMID:18006707) UniProt PMID:18006707 NCBI chr17:17,188,390...17,196,315
Ensembl chr17:17,409,669...17,417,600
JBrowse link
G PGRMC1 progesterone receptor membrane component 1 enables ISO (PMID:26988023), (PMID:27599036)
UniProt PMID:26988023 PMID:27599036 PMID:31748741 MGI:6393146 NCBI chr  X:108,282,958...108,291,187
Ensembl chr  X:118,711,495...118,719,714
JBrowse link
G PGRMC2 progesterone receptor membrane component 2 enables ISO (PMID:28111073)
UniProt PMID:28111073 PMID:31748741 MGI:6393146 NCBI chr 4:120,429,896...120,449,131
Ensembl chr 4:131,730,824...131,751,094
JBrowse link
G PRDX1 peroxiredoxin 1 ISO RGD PMID:7577926 RGD:729570 NCBI chr 1:44,813,508...44,824,430
Ensembl chr 1:46,171,453...46,182,018
JBrowse link
G PTGIS prostaglandin I2 synthase enables ISO (PMID:17020766), (PMID:18032380) UniProt PMID:17020766 PMID:18032380 NCBI chr20:45,841,238...45,905,641
Ensembl chr20:46,905,665...46,971,612
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 enables ISO (MGI:5315361|PMID:12925531) UniProt PMID:12925531 MGI:5315361 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PXDN peroxidasin enables ISO (PMID:18929642) UniProt PMID:18929642 NCBI chr2A:1,584,901...1,699,675
Ensembl chr2A:1,582,193...1,692,033
JBrowse link
G RSAD1 radical S-adenosyl methionine domain containing 1 enables ISO (PMID:29282292) UniProt PMID:29282292 NCBI chr17:44,573,168...44,580,324
Ensembl chr17:49,446,933...49,454,110
JBrowse link
G SDHC succinate dehydrogenase complex subunit C enables ISO (PMID:15989954) UniProt PMID:15989954 NCBI chr 1:136,724,663...136,773,038
Ensembl chr 1:140,635,685...140,682,736
JBrowse link
G SDHD succinate dehydrogenase complex subunit D enables ISO (PMID:15989954) UniProt PMID:15989954 NCBI chr11:106,973,256...106,982,237
Ensembl chr11:110,817,016...110,896,829
JBrowse link
G SLC48A1 solute carrier family 48 member 1 enables ISO (PMID:18418376) WB PMID:18418376 NCBI chr12:40,950,511...40,977,994 JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase enables ISO (PMID:21036157) UniProt PMID:21036157 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G STC2 stanniocalcin 2 enables ISO (PMID:22503972) UniProt PMID:22503972 NCBI chr 5:168,668,851...168,681,274
Ensembl chr 5:175,575,419...175,587,832
JBrowse link
G STEAP4 STEAP4 metalloreductase enables ISO (PMID:30337524) UniProt PMID:30337524 NCBI chr 7:80,263,528...80,299,470
Ensembl chr 7:93,918,327...93,948,754
JBrowse link
G SUOX sulfite oxidase ISO RGD PMID:8276806 RGD:634113 NCBI chr12:32,907,456...32,915,788
Ensembl chr12:33,157,277...33,165,661
JBrowse link
G TBXAS1 thromboxane A synthase 1 enables ISO (PMID:11097184) UniProt PMID:11097184 NCBI chr 7:131,772,947...131,958,647
Ensembl chr 7:144,255,211...144,439,523
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase enables ISO (PMID:27762317), (PMID:28285122) RGD
PMID:3400092 PMID:27762317 PMID:28285122 RGD:2290313 NCBI chr 4:148,269,097...148,285,533
Ensembl chr 4:160,085,645...160,102,266
JBrowse link
G THAP4 THAP domain containing 4 enables ISO (PMID:21387410) UniProt PMID:21387410 NCBI chr2B:128,858,512...128,913,474
Ensembl chr2B:247,650,249...247,701,219
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 15014
    binding 14203
      heterocyclic compound binding 2538
        tetrapyrrole binding 59
          heme binding 54
paths to the root