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ONTOLOGY REPORT - ANNOTATIONS


Term:hemoglobin metabolic process
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Accession:GO:0020027 term browser browse the term
Definition:The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
Synonyms:exact_synonym: haemoglobin metabolic process;   haemoglobin metabolism;   hemoglobin metabolism



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hemoglobin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3806792|PMID:18723693) MGI
Ensembl
PMID:18723693 GO_REF:0000107 MGI:3806792 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G AHSP alpha hemoglobin stabilizing protein involved_in NAS (PMID:12066189) UniProt
UniProt
PMID:12066189 NCBI chr16:31,527,900...31,528,803
Ensembl chr16:31,527,900...31,528,803
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor involved_in IDA (PMID:15683711) UniProt
UniProt
PMID:15683711 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within ISO MGI MGI:48782 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723
JBrowse link
G CAT catalase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:66714|PMID:8153151) Ensembl
Ensembl
MGI
PMID:8153151 GO_REF:0000107 MGI:66714 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G EPB42 erythrocyte membrane protein band 4.2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1930623|PMID:10359562) Ensembl
Ensembl
MGI
PMID:10359562 GO_REF:0000107 MGI:1930623 NCBI chr15:43,197,227...43,225,737
Ensembl chr15:43,197,227...43,221,018
JBrowse link
G HPX hemopexin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1350473|PMID:10572107) Ensembl
Ensembl
MGI
PMID:10572107 GO_REF:0000107 MGI:1350473 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAS1 5'-aminolevulinate synthase 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 involved_in ISS
IEA
IBA
(PMID:21873635) UniProt
Ensembl
GO_Central
UniProt
GO_Central
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:55,009,055...55,030,977
Ensembl chr  X:55,009,055...55,030,977
JBrowse link
G EPO erythropoietin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3762687|PMID:17300687) Ensembl
Ensembl
MGI
PMID:17300687 GO_REF:0000107 MGI:3762687 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3695187|PMID:16787915) Ensembl
MGI
Ensembl
PMID:16787915 GO_REF:0000107 MGI:3695187 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G INHA inhibin subunit alpha involved_in IDA (PMID:1310063) UniProt
UniProt
PMID:1310063 NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711
JBrowse link
G INHBA inhibin subunit beta A involved_in IDA (PMID:1310063) UniProt
UniProt
PMID:1310063 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G SNX3 sorting nexin 3 acts_upstream_of_or_within ISO (MGI:5495606|PMID:23416069) MGI PMID:23416069 MGI:5495606 NCBI chr 6:108,211,222...108,261,040
Ensembl chr 6:108,211,222...108,261,246
JBrowse link
negative regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175
JBrowse link
positive regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB10 ATP binding cassette subfamily B member 10 involved_in IMP (PMID:22085049), (PMID:28808058) UniProt
UniProt
PMID:22085049 PMID:28808058 NCBI chr 1:229,516,582...229,558,707
Ensembl chr 1:229,516,582...229,558,707
JBrowse link
G KLF4 KLF transcription factor 4 involved_in IMP (PMID:21539536) BHF-UCL
BHF-UCL
PMID:21539536 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G LDB1 LIM domain binding 1 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,102,088...102,121,442
Ensembl chr10:102,106,489...102,120,368
JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029
JBrowse link
G SLC25A37 solute carrier family 25 member 37 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:23,528,956...23,575,463
Ensembl chr 8:23,528,956...23,575,463
JBrowse link
G SLC6A9 solute carrier family 6 member 9 involved_in ISS ARUK-UCL
ARUK-UCL
GO_REF:0000024 NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
JBrowse link
regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3581470|PMID:15931390) Ensembl
MGI
PMID:15931390 GO_REF:0000107 MGI:3581470 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175
JBrowse link
G FECH ferrochelatase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3581470|PMID:15931390) MGI
Ensembl
PMID:15931390 GO_REF:0000107 MGI:3581470 NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19751
    metabolic process 13170
      cellular metabolic process 10979
        cellular macromolecule metabolic process 3584
          hemoglobin metabolic process 23
            hemoglobin biosynthetic process + 15
            hemoglobin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19751
    metabolic process 13170
      organic substance metabolic process 12698
        macromolecule metabolic process 11051
          protein metabolic process 6031
            hemoglobin metabolic process 23
              hemoglobin biosynthetic process + 15
              hemoglobin catabolic process 0
paths to the root