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ONTOLOGY REPORT - ANNOTATIONS


Term:hemoglobin metabolic process
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Accession:GO:0020027 term browser browse the term
Definition:The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
Synonyms:exact_synonym: haemoglobin metabolic process;   haemoglobin metabolism;   hemoglobin metabolism



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hemoglobin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 acts_upstream_of_or_within ISO (MGI:3806792|PMID:18723693) MGI PMID:18723693 MGI:3806792 NCBI chr 3:61,356,643...61,443,851
Ensembl chr 3:61,358,162...61,474,830
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor involved_in ISO (PMID:15683711) UniProt PMID:15683711 NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994
JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within ISO MGI MGI:48782 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343
JBrowse link
G CAT catalase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:66714|PMID:8153151) Ensembl
Ensembl
MGI
PMID:8153151 GO_REF:0000107 MGI:66714 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G EPB42 erythrocyte membrane protein band 4.2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1930623|PMID:10359562) MGI
Ensembl
Ensembl
PMID:10359562 GO_REF:0000107 MGI:1930623 NCBI chr30:10,065,352...10,085,021
Ensembl chr30:10,065,469...10,084,976
JBrowse link
G HPX hemopexin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1350473|PMID:10572107) Ensembl
MGI
PMID:10572107 GO_REF:0000107 MGI:1350473 NCBI chr21:29,749,913...29,759,176
Ensembl chr21:29,719,589...29,759,046
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAS1 5'-aminolevulinate synthase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:37,552,813...37,566,417
Ensembl chr20:37,552,814...37,566,638
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:46,703,477...46,731,767
Ensembl chr  X:46,703,477...46,723,529
JBrowse link
G EPO erythropoietin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3762687|PMID:17300687) MGI
Ensembl
PMID:17300687 GO_REF:0000107 MGI:3762687 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3695187|PMID:16787915) Ensembl
Ensembl
MGI
PMID:16787915 GO_REF:0000107 MGI:3695187 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G INHA inhibin subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:26,080,465...26,083,570
Ensembl chr37:26,080,510...26,083,391
JBrowse link
G INHBA inhibin subunit beta A involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794
JBrowse link
G SNX3 sorting nexin 3 acts_upstream_of_or_within ISO (MGI:5495606|PMID:23416069) MGI PMID:23416069 MGI:5495606 NCBI chr12:65,252,175...65,294,620
Ensembl chr12:65,252,175...65,294,611
JBrowse link
negative regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658
JBrowse link
positive regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB10 ATP binding cassette subfamily B member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:9,711,509...9,746,785
Ensembl chr 4:9,711,100...9,745,106
JBrowse link
G KLF4 KLF transcription factor 4 involved_in ISO (PMID:21539536) BHF-UCL PMID:21539536 NCBI chr11:62,881,840...62,886,676
Ensembl chr11:62,882,767...62,928,251
JBrowse link
G LDB1 LIM domain binding 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:14,646,409...14,658,324
Ensembl chr28:14,646,056...14,658,548
JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075
JBrowse link
G SLC25A37 solute carrier family 25 member 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:33,923,108...33,965,577
Ensembl chr25:33,894,132...33,965,398
JBrowse link
G SLC6A9 solute carrier family 6 member 9 involved_in ISO (MGI:6450351|PMID:28495915) ARUK-UCL PMID:28495915 MGI:6450351 NCBI chr15:16,235,342...16,267,161
Ensembl chr15:16,235,482...16,267,933
JBrowse link
regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3581470|PMID:15931390) Ensembl
MGI
PMID:15931390 GO_REF:0000107 MGI:3581470 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658
JBrowse link
G FECH ferrochelatase acts_upstream_of_or_within ISO (MGI:3581470|PMID:15931390) MGI PMID:15931390 MGI:3581470 NCBI chr 1:18,352,184...18,384,251
Ensembl chr 1:18,345,811...18,383,092
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17341
    metabolic process 11291
      cellular metabolic process 9486
        cellular macromolecule metabolic process 3355
          hemoglobin metabolic process 22
            hemoglobin biosynthetic process + 15
            hemoglobin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 17341
    metabolic process 11291
      organic substance metabolic process 10868
        macromolecule metabolic process 9423
          protein metabolic process 5702
            hemoglobin metabolic process 22
              hemoglobin biosynthetic process + 15
              hemoglobin catabolic process 0
paths to the root