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ONTOLOGY REPORT - ANNOTATIONS


Term:hemoglobin metabolic process
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Accession:GO:0020027 term browser browse the term
Definition:The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
Synonyms:exact_synonym: haemoglobin metabolic process;   haemoglobin metabolism;   hemoglobin metabolism


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hemoglobin metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 IEA
ISO
GO_REF:0000107
MGI:3799499 (MGI:3806792|PMID:18723693)
Ensembl
RGD
PMID:18723693 GO_REF:0000107, MGI:3806792 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Axin1 axin 1 ISO MGI:1856035 RGD MGI:48782
G Cat catalase ISO MGI:3053604 (MGI:66714|PMID:8153151) RGD PMID:8153151 MGI:66714 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 ISO MGI:2182816 (MGI:1930623|PMID:10359562) RGD PMID:10359562 MGI:1930623 NCBI chr 3:112,967,095...112,985,318
Ensembl chr 3:112,965,653...112,985,318
JBrowse link
G Hpx hemopexin ISO MGI:2447193 (MGI:1350473|PMID:10572107) RGD PMID:10572107 MGI:1350473 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO MGI:5301343 (MGI:5298314|PMID:21803851) RGD PMID:21803851 MGI:5298314 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
hemoglobin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alas1 5'-aminolevulinate synthase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:3694153|PMID:9446639)
PMID:21873635
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9446639, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:3694153, RGD:13792537 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Epo erythropoietin ISO (MGI:3762687|PMID:17300687) RGD PMID:17300687 MGI:3762687 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEA
ISO
GO_REF:0000107
MGI:1857719 (MGI:3695187|PMID:16787915)
Ensembl
RGD
PMID:16787915 GO_REF:0000107, MGI:3695187 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Inha inhibin subunit alpha ISO
ISS
(PMID:1310063)
GO_REF:0000024
RGD
UniProt
PMID:1310063 GO_REF:0000024 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Inhba inhibin subunit beta A ISO
ISS
(PMID:1310063)
GO_REF:0000024
RGD
UniProt
PMID:1310063 GO_REF:0000024 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Snx3 sorting nexin 3 ISO (MGI:5495606|PMID:23416069) RGD PMID:23416069 MGI:5495606 NCBI chr20:47,225,382...47,263,390
Ensembl chr20:47,225,619...47,263,390
JBrowse link
negative regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 ISS
ISO
GO_REF:0000024
(MGI:3687799|PMID:11050009)
UniProt
RGD
PMID:11050009 GO_REF:0000024, MGI:3687799 NCBI chr12:12,749,026...12,782,078
Ensembl chr12:12,748,785...12,782,146
JBrowse link
positive regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf4 Kruppel like factor 4 ISO (PMID:21539536) RGD PMID:21539536 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Ldb1 LIM domain binding 1 ISO (MGI:4834059|PMID:20570862) RGD PMID:20570862 MGI:4834059 NCBI chr 1:265,772,729...265,798,442
Ensembl chr 1:265,785,409...265,798,167
JBrowse link
G Prmt1 protein arginine methyltransferase 1 IDA PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
JBrowse link
G Slc6a9 solute carrier family 6 member 9 IEA
ISO
GO_REF:0000107
(MGI:6450351|PMID:28495915)
Ensembl
RGD
PMID:28495915 GO_REF:0000107, MGI:6450351 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 ISO MGI:1353448|MGI:95513 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr12:12,749,026...12,782,078
Ensembl chr12:12,748,785...12,782,146
JBrowse link
G Fech ferrochelatase ISO MGI:1353448|MGI:95513 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular macromolecule metabolic process 8548
          hemoglobin metabolic process 19
            hemoglobin biosynthetic process + 13
            hemoglobin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          protein metabolic process 6221
            hemoglobin metabolic process 19
              hemoglobin biosynthetic process + 13
              hemoglobin catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.