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ONTOLOGY REPORT - ANNOTATIONS

Term:hemoglobin metabolic process
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Accession:GO:0020027 term browser browse the term
Definition:The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
Synonyms:exact_synonym: haemoglobin metabolic process;   haemoglobin metabolism;   hemoglobin metabolism


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hemoglobin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3799499 (PMID:18723693)		 Ensembl
RGD		 PMID:18723693 GO_REF:0000107 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor involved_in ISO
ISS		 (PMID:15683711)
GO_REF:0000024		 RGD
UniProt		 PMID:15683711 GO_REF:0000024 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO MGI:1856035 RGD MGI:48782 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Cat catalase acts_upstream_of_or_within ISO MGI:3053604 (PMID:8153151) RGD PMID:8153151 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 acts_upstream_of_or_within ISO MGI:2182816 (PMID:10359562) RGD PMID:10359562 NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (PMID:10572107) RGD PMID:10572107 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within ISO MGI:5301343 (PMID:21803851) RGD PMID:21803851 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alas1 5'-aminolevulinate synthase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 involved_in IEA
ISS
IBA
ISO		 GO_REF:0000107
GO_REF:0000024
GO_REF:0000033
(PMID:9446639)		 Ensembl
UniProt
GO_Central
RGD		 PMID:9446639 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Epo erythropoietin acts_upstream_of_or_within ISO (PMID:17300687) RGD PMID:17300687 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857719 (PMID:16787915)		 Ensembl
RGD		 PMID:16787915 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Inha inhibin subunit alpha involved_in ISO
ISS		 (PMID:1310063)
GO_REF:0000024		 RGD
UniProt		 PMID:1310063 GO_REF:0000024 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS		 (PMID:1310063)
GO_REF:0000024		 RGD
UniProt		 PMID:1310063 GO_REF:0000024 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Snx3 sorting nexin 3 acts_upstream_of_or_within ISO (PMID:23416069) RGD PMID:23416069 NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379 		JBrowse link
negative regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11050009)		 UniProt
Ensembl
RGD		 PMID:11050009 GO_REF:0000024 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
positive regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO (PMID:22085049), (PMID:28808058) RGD PMID:22085049 PMID:28808058 NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:21539536) RGD PMID:21539536 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Ldb1 LIM domain binding 1 involved_in ISO (PMID:20570862) RGD PMID:20570862 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in IDA PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19805291)		 UniProt
RGD		 PMID:19805291 GO_REF:0000024 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO (PMID:28495915) RGD PMID:28495915 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        primary metabolic process 10579
          protein metabolic process 5296
            hemoglobin metabolic process 22
              hemoglobin biosynthetic process + 15
              hemoglobin catabolic process 0
paths to the root