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ONTOLOGY REPORT - ANNOTATIONS

Term:L-ascorbic acid biosynthetic process
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Accession:GO:0019853 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:exact_synonym: L-ascorbic acid anabolism;   L-ascorbic acid biosynthesis;   L-ascorbic acid formation;   L-ascorbic acid synthesis;   ascorbate biosynthesis;   ascorbate biosynthetic process;   vitamin C biosynthesis;   vitamin C biosynthetic process
 xref: MetaCyc:PWY-882
 never_in_taxon: NCBITaxon:4890 ! Ascomycota;   NCBITaxon:9606 ! Homo sapiens

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L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within		 ISO PMID:22820017
(PMID:20410296)
(PMID:15769935)		 UniProt
MGI		 PMID:15769935 PMID:20410296 PMID:22820017 RGD:13825440 NCBI chrNW_004955464:12,715,238...12,729,034
Ensembl chrNW_004955464:12,714,717...12,729,662 		JBrowse link
G Rgn regucalcin involved_in ISO (PMID:16585534)
(PMID:23349732)		 MGI
UniProt		 PMID:16585534 PMID:23349732 NCBI chrNW_004955516:958,416...978,829
Ensembl chrNW_004955516:955,680...978,910 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      metabolic process 7974
        biosynthetic process 5509
          lactone biosynthetic process 2
            L-ascorbic acid biosynthetic process 2
              L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
              L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
              negative regulation of L-ascorbic acid biosynthetic process 0
              regulation of L-ascorbic acid biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      metabolic process 7974
        small molecule metabolic process 1327
          organic acid metabolic process 685
            oxoacid metabolic process 679
              carboxylic acid metabolic process 671
                L-ascorbic acid metabolic process 9
                  L-ascorbic acid biosynthetic process 2
                    L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
                    L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
                    negative regulation of L-ascorbic acid biosynthetic process 0
                    regulation of L-ascorbic acid biosynthetic process + 0
paths to the root