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ONTOLOGY REPORT - ANNOTATIONS

Term:L-ascorbic acid biosynthetic process
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Accession:GO:0019853 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:exact_synonym: L-ascorbic acid anabolism;   L-ascorbic acid biosynthesis;   L-ascorbic acid formation;   L-ascorbic acid synthesis;   ascorbate biosynthesis;   ascorbate biosynthetic process;   vitamin C biosynthesis;   vitamin C biosynthetic process
 xref: MetaCyc:PWY-882


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L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:22820017
(PMID:15769935)
MGI:4239556 (PMID:20410296)		 RGD PMID:15769935 PMID:20410296 PMID:22820017 RGD:13825440 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO MGI:5008171 (PMID:20410296) RGD PMID:20410296 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,205,677...40,227,766
Ensembl chr15:40,205,665...40,227,874 		JBrowse link
G Rgn regucalcin involved_in ISS
ISO
IBA		 GO_REF:0000024
MGI:2670511 (PMID:16585534), (PMID:23349732)
MGI:2670511 (MGI:5486063|PMID:23349732), (PMID:16585534)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:16585534 PMID:23349732 GO_REF:0000024 GO_REF:0000033 MGI:5486063 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        biosynthetic process 8436
          lactone biosynthetic process 5
            L-ascorbic acid biosynthetic process 5
              L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
              L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
              negative regulation of L-ascorbic acid biosynthetic process 0
              regulation of L-ascorbic acid biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        small molecule metabolic process 1899
          organic acid metabolic process 1034
            oxoacid metabolic process 1023
              carboxylic acid metabolic process 1008
                carboxylic acid biosynthetic process 326
                  L-ascorbic acid biosynthetic process 5
                    L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
                    L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
                    negative regulation of L-ascorbic acid biosynthetic process 0
                    regulation of L-ascorbic acid biosynthetic process + 0
paths to the root