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ONTOLOGY REPORT - ANNOTATIONS


Term:L-ascorbic acid biosynthetic process
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Accession:GO:0019853 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:exact_synonym: L-ascorbic acid anabolism;   L-ascorbic acid biosynthesis;   L-ascorbic acid formation;   L-ascorbic acid synthesis;   ascorbate biosynthesis;   ascorbate biosynthetic process;   vitamin C biosynthesis;   vitamin C biosynthetic process
 xref: MetaCyc:PWY-882


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L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within
IMP
ISO
PMID:22820017
(MGI:4834110|PMID:20410296)
(MGI:3588122|PMID:15769935)
RGD PMID:15769935 PMID:20410296, PMID:22820017 MGI:3588122 MGI:4834110, RGD:13825440 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in IEA
ISS
GO_REF:0000107
GO_REF:0000024
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr15:42,671,206...42,693,711
Ensembl chr15:42,671,203...42,693,694
JBrowse link
G Rgn regucalcin involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5486063|PMID:23349732)
GO_REF:0000024
RGD
UniProt
PMID:23349732, PMID:21873635 GO_REF:0000024 MGI:5486063, RGD:13792537 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      small molecule metabolic process 1786
        monosaccharide metabolic process 280
          monosaccharide biosynthetic process 92
            L-ascorbic acid biosynthetic process 4
              L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
              L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
              negative regulation of L-ascorbic acid biosynthetic process 0
              regulation of L-ascorbic acid biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      cellular metabolic process 10847
        organic acid metabolic process 1006
          oxoacid metabolic process 969
            carboxylic acid metabolic process 951
              carboxylic acid biosynthetic process 287
                L-ascorbic acid biosynthetic process 4
                  L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
                  L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
                  negative regulation of L-ascorbic acid biosynthetic process 0
                  regulation of L-ascorbic acid biosynthetic process + 0
paths to the root