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ONTOLOGY REPORT - ANNOTATIONS


Term:L-ascorbic acid biosynthetic process
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Accession:GO:0019853 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:exact_synonym: L-ascorbic acid anabolism;   L-ascorbic acid biosynthesis;   L-ascorbic acid formation;   L-ascorbic acid synthesis;   ascorbate biosynthesis;   ascorbate biosynthetic process;   vitamin C biosynthesis;   vitamin C biosynthetic process
 xref: MetaCyc:PWY-882



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L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within
IMP
ISO
PMID:22820017
(MGI:4834110|PMID:20410296)
(MGI:3588122|PMID:15769935)
RGD PMID:15769935 PMID:20410296 PMID:22820017 MGI:3588122 MGI:4834110, RGD:13825440 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA
GO_REF:0000024
GO_REF:0000041
GO_REF:0000107
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr15:40,205,677...40,227,766
Ensembl chr15:40,205,665...40,227,874
JBrowse link
G Rgn regucalcin involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5486063|PMID:23349732)
GO_REF:0000024
RGD
UniProt
PMID:23349732 PMID:21873635 GO_REF:0000024 MGI:5486063, RGD:13792537 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      small molecule metabolic process 1806
        monosaccharide metabolic process 280
          monosaccharide biosynthetic process 93
            L-ascorbic acid biosynthetic process 4
              L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
              L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
              negative regulation of L-ascorbic acid biosynthetic process 0
              regulation of L-ascorbic acid biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19541
    cellular process 18407
      cellular metabolic process 10738
        organic acid metabolic process 1016
          oxoacid metabolic process 984
            carboxylic acid metabolic process 963
              L-ascorbic acid metabolic process 8
                L-ascorbic acid biosynthetic process 4
                  L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
                  L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
                  negative regulation of L-ascorbic acid biosynthetic process 0
                  regulation of L-ascorbic acid biosynthetic process + 0
paths to the root