L-ascorbic acid biosynthetic process - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	L-ascorbic acid biosynthetic process	go back to main search page
Accession:	GO:0019853	browse the term
Definition:	The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:	exact_synonym:	L-ascorbic acid anabolism; L-ascorbic acid biosynthesis; L-ascorbic acid formation; L-ascorbic acid synthesis; ascorbate biosynthesis; ascorbate biosynthetic process; vitamin C biosynthesis; vitamin C biosynthetic process
	xref:	MetaCyc:PWY-882

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Genes (4)

L-ascorbic acid biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akr1a1

aldo-keto reductase family 1 member A1

involved_in
acts_upstream_of_or_within

IMP
ISO

PMID:22820017
(MGI:4834110|PMID:20410296)
(MGI:3588122|PMID:15769935)

RGD

PMID:15769935 PMID:20410296, PMID:22820017

MGI:3588122 MGI:4834110, RGD:13825440

NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822

Gsto1

glutathione S-transferase omega 1

IMP

RGD

PMID:9786866

RGD:70644

NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387

Gulo

gulonolactone (L-) oxidase

involved_in

IEA
ISS

GO_REF:0000107
GO_REF:0000024

Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr15:42,671,206...42,693,711
Ensembl chr15:42,671,203...42,693,694

Rgn

regucalcin

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:5486063|PMID:23349732)
GO_REF:0000024

RGD
UniProt

PMID:23349732, PMID:21873635

GO_REF:0000024 MGI:5486063, RGD:13792537

NCBI chr X:1,833,484...1,848,904
Ensembl chr X:1,833,492...1,848,904

Term paths to the root

Path 1
Term	Annotations
biological_process	19638
metabolic process	11894
small molecule metabolic process	1786
monosaccharide metabolic process	280
monosaccharide biosynthetic process	92
L-ascorbic acid biosynthetic process	4
L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	0
L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	0
negative regulation of L-ascorbic acid biosynthetic process	0
regulation of L-ascorbic acid biosynthetic process +	0
Path 2
Term	Annotations
biological_process	19638
metabolic process	11894
cellular metabolic process	10847
organic acid metabolic process	1006
oxoacid metabolic process	969
carboxylic acid metabolic process	951
carboxylic acid biosynthetic process	287
L-ascorbic acid biosynthetic process	4
L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	0
L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	0
negative regulation of L-ascorbic acid biosynthetic process	0
regulation of L-ascorbic acid biosynthetic process +	0

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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ONTOLOGY REPORT - ANNOTATIONS