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ONTOLOGY REPORT - ANNOTATIONS


Term:L-ascorbic acid metabolic process
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Accession:GO:0019852 term browser browse the term
Definition:The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
Synonyms:exact_synonym: L-ascorbic acid metabolism;   ascorbate metabolic process;   ascorbate metabolism;   vitamin C metabolic process;   vitamin C metabolism



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L-ascorbic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88107 (PMID:33544780)
Ensembl
RGD
PMID:33544780 GO_REF:0000107 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:88106 (PMID:33544780) RGD PMID:33544780 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Clstn3 calsyntenin 3 involved_in ISO (PMID:34673103)
(MGI:6728656|PMID:33672967)
RGD PMID:33672967 PMID:34673103 MGI:6728656 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2429419 (PMID:11118286) RGD PMID:11118286 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO
IBA
IEA
ISS
(PMID:11511179)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000024
RGD
GO_Central
TreeGrafter
UniProt
PMID:11511179 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISO
IBA
IEA
ISS
(PMID:15970797)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
TreeGrafter
Ensembl
UniProt
PMID:15970797 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:27085842 RGD:26884454 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Selenon selenoprotein N acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059
JBrowse link
G Slc23a2 solute carrier family 23 member 2 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:10331392 GO_REF:0000033, RGD:634186 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within
IMP
ISO
PMID:22820017
MGI:4239556 (PMID:20410296)
(PMID:15769935)
RGD PMID:15769935 PMID:20410296 PMID:22820017 RGD:13825440 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO MGI:5008171 (PMID:20410296) RGD PMID:20410296 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA
GO_REF:0000024
GO_REF:0000107
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,205,677...40,227,766
Ensembl chr15:40,205,665...40,227,874
JBrowse link
G Rgn regucalcin involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
MGI:2670511 (MGI:5486063|PMID:23349732), (PMID:16585534)
UniProt
GO_Central
RGD
PMID:16585534 PMID:23349732 GO_REF:0000024 GO_REF:0000033 MGI:5486063 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      small molecule metabolic process 1938
        monosaccharide metabolic process 285
          L-ascorbic acid metabolic process 14
            L-ascorbic acid biosynthetic process + 5
            L-ascorbic acid catabolic process 0
            ascorbate glutathione cycle 0
Path 2
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular metabolic process 10279
        organic acid metabolic process 1074
          oxoacid metabolic process 1056
            carboxylic acid metabolic process 1037
              L-ascorbic acid metabolic process 14
                L-ascorbic acid biosynthetic process + 5
                L-ascorbic acid catabolic process 0
                ascorbate glutathione cycle 0
paths to the root