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ONTOLOGY REPORT - ANNOTATIONS


Term:growth factor binding
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Accession:GO:0019838 term browser browse the term
Definition:Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.
Synonyms:related_synonym: neurotrophin TRK receptor activity
 never_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:2157 ! Archaea;   NCBITaxon:4751 ! Fungi


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growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 ISO (MGI:73273|PMID:8388127) MGI PMID:8388127 MGI:73273 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G ACVR1B activin A receptor type 1B contributes_to ISO (PMID:14517293) HGNC PMID:14517293 NCBI chr12:36,765,655...36,811,355
Ensembl chr12:37,541,867...37,566,660
JBrowse link
G ACVR1C activin A receptor type 1C enables ISO (PMID:21805089) UniProt PMID:21805089 NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151
JBrowse link
G ACVR2A activin A receptor type 2A ISO (MGI:2137985|PMID:11459935)
(MGI:2389524|PMID:12414726)
MGI PMID:11459935 PMID:12414726 MGI:2137985 MGI:2389524 NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385
JBrowse link
G ACVR2B activin A receptor type 2B enables ISO (MGI:2137985|PMID:11459935)
(PMID:14517293)
(MGI:2389524|PMID:12414726)
MGI
HGNC-UCL
PMID:11459935 PMID:12414726 PMID:14517293 MGI:2137985 MGI:2389524 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO RGD PMID:11044210 RGD:5129485 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:18929742 RGD:10044027 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G EPHA2 EPH receptor A2 enables ISO (PMID:22568954) ARUK-UCL PMID:22568954 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G EPHA5 EPH receptor A5 enables ISO PMID:22568954 ARUK-UCL PMID:22568954 RGD:40902966 NCBI chr 4:58,392,771...58,743,604 JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 contributes_to ISO (PMID:7514177) BHF-UCL PMID:7514177 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 enables ISO (PMID:11389077) BHF-UCL PMID:11389077 NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 enables ISO (PMID:10471394), (PMID:11513746), (PMID:1312256)
(PMID:12366396), (PMID:16109918)
RGD
UniProt
PMID:1312256 PMID:10471394 PMID:11513746 PMID:12366396 PMID:16109918 PMID:17651752 RGD:2289969 NCBI chr13:9,584,850...9,779,542 JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 enables ISO (PMID:9435229) RGD
UniProt
PMID:9435229 PMID:11683876 RGD:727326 NCBI chr 5:175,804,728...175,852,703
Ensembl chr 5:183,115,856...183,149,006
JBrowse link
G GHR growth hormone receptor enables ISO (PMID:9360546) BHF-UCL PMID:9360546 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278
JBrowse link
G GHRHR growth hormone releasing hormone receptor enables ISO (PMID:7680413) BHF-UCL PMID:7680413 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200
JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer contributes_to
enables
ISO (PMID:8999038) BHF-UCL PMID:8999038 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817
JBrowse link
G KDR kinase insert domain receptor enables ISO (PMID:10022831), (PMID:1417831)
(MGI:83765|PMID:7681362)
(MGI:1860784|PMID:10705382)
RGD
BHF-UCL
MGI
PMID:1417831 PMID:7681362 PMID:9160888 PMID:9442048 PMID:10022831 PMID:10705382 MGI:1860784 MGI:83765 RGD:2292115 RGD:729081 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G LIFR LIF receptor subunit alpha enables ISO (PMID:8999038) BHF-UCL PMID:8999038 NCBI chr 5:71,817,431...71,899,101
Ensembl chr 5:76,878,633...76,928,267
JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 enables ISO (PMID:15064403) BHF-UCL PMID:15064403 NCBI chr 5:1,285,217...1,311,285
Ensembl chr 5:1,075,172...1,081,664
JBrowse link
G NRP1 neuropilin 1 enables ISO (MGI:1860784|PMID:10705382)
(PMID:9529250)
MGI
UniProt
PMID:9529250 PMID:10705382 MGI:1860784 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648
JBrowse link
G OSMR oncostatin M receptor enables ISO (PMID:8999038) BHF-UCL PMID:8999038 NCBI chr 5:71,437,589...71,525,521
Ensembl chr 5:76,478,699...76,543,263
JBrowse link
G SDCBP syndecan binding protein ISO RGD PMID:11152476 RGD:633988 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833
JBrowse link
G TEK TEK receptor tyrosine kinase ISO RGD PMID:15714275 RGD:1578337 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 contributes_to ISO (PMID:14517293) HGNC PMID:14517293 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:17881084 RGD:2292001 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
brain-derived neurotrophic factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSTL4 follistatin like 4 ISO (MGI:5566541|PMID:24573299) MGI PMID:24573299 MGI:5566541 NCBI chr 5:128,606,171...129,016,734
Ensembl chr 5:134,766,944...135,163,711
JBrowse link
G HAP1 huntingtin associated protein 1 ISO PMID:21357693
PMID:19996106
UniProt PMID:19996106 PMID:21357693 RGD:10047154 RGD:10047187 NCBI chr17:15,578,658...15,596,313
Ensembl chr17:15,797,949...15,810,299
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO (MGI:893826|PMID:1645620) RGD
UniProt
PMID:1645620 PMID:16477614 PMID:16983663 MGI:893826 RGD:1626130 RGD:1626131 RGD:8554777 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678
JBrowse link
epidermal growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor ISO (MGI:52273|PMID:7678348) RGD
MGI
PMID:7678348 PMID:15486316 MGI:52273 RGD:1581908 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G SEC61B SEC61 translocon subunit beta enables ISO (PMID:19602593) UniProt PMID:19602593 NCBI chr 9:70,312,061...70,320,448
Ensembl chr 9:98,431,059...98,438,914
JBrowse link
G SHC1 SHC adaptor protein 1 ISO (MGI:3057041|PMID:15467833) UniProt PMID:15467833 MGI:3057041 NCBI chr 1:130,310,778...130,323,001
Ensembl chr 1:133,920,532...133,929,008
JBrowse link
fibroblast growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G API5 apoptosis inhibitor 5 enables ISO (PMID:11075807) UniProt PMID:11075807 NCBI chr11:43,279,024...43,311,602
Ensembl chr11:43,759,414...43,791,975
JBrowse link
G CEP57 centrosomal protein 57 enables ISO (PMID:12717444) UniProt PMID:12717444 NCBI chr11:90,795,277...90,838,166 JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 enables ISO (PMID:11708770) BHF-UCL PMID:11708770 NCBI chr 4:46,583,759...46,589,865
Ensembl chr 4:52,428,702...52,434,803
JBrowse link
G FGFBP1 fibroblast growth factor binding protein 1 ISO (MGI:4949582|PMID:20851768)
(MGI:3589509|PMID:15806171)
UniProt
MGI
PMID:15806171 PMID:20851768 MGI:3589509 MGI:4949582 NCBI chr 4:10,374,303...10,377,210
Ensembl chr 4:15,671,516...15,672,220
JBrowse link
G FGFBP3 fibroblast growth factor binding protein 3 enables ISO (MGI:4949582|PMID:20851768)
(PMID:18669637)
UniProt
MGI
PMID:18669637 PMID:20851768 MGI:4949582 NCBI chr10:88,655,350...88,657,282 JBrowse link
G FGFR1 fibroblast growth factor receptor 1 enables ISO (MGI:79015|PMID:2161540)
(PMID:18480409), (PMID:8663044)
(MGI:3696596|PMID:17086194)
MGI
UniProt
PMID:2161540 PMID:8663044 PMID:17086194 PMID:18480409 MGI:3696596 MGI:79015 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 enables ISO (PMID:11923311), (PMID:19224135)
(PMID:8386828)
(PMID:8663044)
(MGI:1197797|PMID:9435295)
Fgfr2IIIb/Kgfr isoform
RGD
UniProt
MGI
PMID:7803853 PMID:8386828 PMID:8663044 PMID:9435295 PMID:11042206 PMID:11923311 PMID:15282342 PMID:19224135 MGI:1197797 RGD:2289853 RGD:632663 RGD:6480435 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 enables ISO (PMID:12815063)
(PMID:8663044)
RGD
MGI
UniProt
PMID:8663044 PMID:12815063 PMID:15231666 RGD:1304345 NCBI chr 4:1,933,172...1,948,742 JBrowse link
G FGFR4 fibroblast growth factor receptor 4 enables ISO (PMID:18480409), (PMID:8663044)
(PMID:10525310), (PMID:17627937)
UniProt PMID:8663044 PMID:10525310 PMID:17627937 PMID:18480409 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605
JBrowse link
G FGFRL1 fibroblast growth factor receptor like 1 ISO (MGI:2148330|PMID:11418238), (MGI:2673744|PMID:12813049) MGI PMID:11418238 PMID:12813049 MGI:2148330 MGI:2673744 NCBI chr 4:1,125,623...1,142,884
Ensembl chr 4:1,045,583...1,059,936
JBrowse link
G FIBP FGF1 intracellular binding protein enables ISO (PMID:9806903) MGI PMID:9806903 NCBI chr11:61,244,175...61,248,805 JBrowse link
G GLG1 golgi glycoprotein 1 ISO RGD PMID:7768993 RGD:68884 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764
JBrowse link
G GPC1 glypican 1 ISO (MGI:4461098|PMID:20100867) UniProt PMID:20100867 MGI:4461098 NCBI chr2B:127,684,839...127,717,294
Ensembl chr2B:246,511,082...246,523,569
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO RGD PMID:10510314 PMID:15030183 RGD:10402562 RGD:6784522 NCBI chr 5:133,934,859...133,955,048
Ensembl chr 5:140,064,207...140,084,551
JBrowse link
G ITGAV integrin subunit alpha V contributes_to ISO (PMID:18441324) UniProtKB PMID:18441324 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028
JBrowse link
G ITGB3 integrin subunit beta 3 contributes_to ISO (PMID:18441324) UniProtKB PMID:18441324 NCBI chr17:10,134,450...10,194,596 JBrowse link
G KL klotho enables ISO (MGI:3696596|PMID:17086194)
(PMID:18829467)
UniProt PMID:17086194 PMID:18829467 MGI:3696596 NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458
JBrowse link
G KLB klotho beta enables ISO (PMID:19117008)
(PMID:18829467)
UniProt PMID:18829467 PMID:19117008 NCBI chr 4:33,736,350...33,780,309
Ensembl chr 4:39,588,702...39,632,480
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:9705269 RGD:9589122 NCBI chr 7:113,882,557...114,073,283
Ensembl chr 7:126,569,630...126,758,155
JBrowse link
G RPS19 ribosomal protein S19 enables ISO (PMID:11716516) BHF-UCL PMID:11716516 NCBI chr19:38,748,604...38,760,055
Ensembl chr19:47,254,157...47,264,953
JBrowse link
G RPS2 ribosomal protein S2 enables ISO (PMID:16263090) UniProt PMID:16263090 NCBI chr16:739,562...742,323
Ensembl chr16:2,051,128...2,054,086
JBrowse link
G S100A13 S100 calcium binding protein A13 enables ISO (PMID:11432880) UniProt PMID:11432880 NCBI chr 1:128,973,910...128,984,234
Ensembl chr 1:132,602,772...132,616,373
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 enables ISO (PMID:12401812) RGD
BHF-UCL
PMID:12401812 RGD:6484231 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:1556106 RGD:1579950 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G THBS1 thrombospondin 1 enables ISO (PMID:17996481) BHF-UCL PMID:17996481 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
hepatocyte growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SRPX2 sushi repeat containing protein X-linked 2 enables ISO (PMID:22242148) UniProt PMID:22242148 NCBI chr  X:89,854,389...89,886,776
Ensembl chr  X:99,994,560...100,021,241
JBrowse link
insulin-like growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1R insulin like growth factor 1 receptor enables ISO (MGI:2679358|PMID:14566968)
(PMID:1846292), (PMID:7679099)
MGI
UniProt
PMID:1846292 PMID:7679099 PMID:14566968 MGI:2679358 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO (MGI:2679358|PMID:14566968) MGI PMID:14566968 MGI:2679358 NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:12446576 RGD:1299153 NCBI chr16:412,671...418,351
Ensembl chr16:1,843,979...1,848,442
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO (MGI:52244|PMID:7679139) MGI PMID:7679139 MGI:52244 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO (MGI:52244|PMID:7679139) MGI PMID:7679139 MGI:52244 NCBI chr2B:103,893,724...103,925,318 JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO (MGI:52244|PMID:7679139) MGI PMID:7679139 MGI:52244 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 ISO (MGI:52244|PMID:7679139) MGI PMID:7679139 MGI:52244 NCBI chr17:16,830,994...16,845,339 JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 ISO (MGI:2679358|PMID:14566968) RGD
MGI
PMID:1709938 PMID:14566968 MGI:2679358 RGD:69857 NCBI chr2B:103,932,983...103,956,475
Ensembl chr2B:222,534,967...222,558,432
JBrowse link
insulin-like growth factor I binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1R insulin like growth factor 1 receptor enables ISO (PMID:19578119)
(PMID:8452530)
UniProt
BHF-UCL
PMID:8452530 PMID:19578119 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 enables ISO (PMID:21550830) UniProt PMID:21550830 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 enables ISO (PMID:19081843)
PMID:2538475
RGD
UniProt
PMID:2538475 PMID:19081843 RGD:729148 NCBI chr2B:103,893,724...103,925,318 JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 enables ISO (PMID:10766744) BHF-UCL PMID:10766744 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 enables ISO (PMID:10766744) BHF-UCL PMID:10766744 NCBI chr2B:103,932,983...103,956,475
Ensembl chr2B:222,534,967...222,558,432
JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 ISO binds with low affinity RGD PMID:7689963 RGD:2301726 NCBI chr12:35,654,172...35,659,115
Ensembl chr12:36,435,221...36,440,132
JBrowse link
G INSR insulin receptor enables ISO (PMID:8452530) BHF-UCL PMID:8452530 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G ITGA6 integrin subunit alpha 6 enables ISO (PMID:22351760) UniProt PMID:22351760 NCBI chr2B:59,714,348...59,794,762
Ensembl chr2B:177,169,536...177,250,143
JBrowse link
G ITGAV integrin subunit alpha V contributes_to ISO (PMID:19578119) BHF-UCL PMID:19578119 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028
JBrowse link
G ITGB3 integrin subunit beta 3 contributes_to ISO (PMID:19578119) UniProtKB PMID:19578119 NCBI chr17:10,134,450...10,194,596 JBrowse link
G ITGB4 integrin subunit beta 4 contributes_to ISO (PMID:22351760) UniProtKB PMID:22351760 NCBI chr17:69,671,252...69,708,520
Ensembl chr17:75,222,376...75,259,401
JBrowse link
G LRP2 LDL receptor related protein 2 enables ISO PMID:16306401 ARUK-UCL PMID:16306401 RGD:14697713 NCBI chr2B:56,407,871...56,640,471
Ensembl chr2B:173,873,767...174,103,697
JBrowse link
insulin-like growth factor II binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF2R insulin like growth factor 2 receptor ISO RGD PMID:16407557 RGD:1624326 NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 enables ISO (PMID:21550830) UniProt PMID:21550830 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 enables ISO PMID:2538475
PMID:2974285
RGD
UniProt
PMID:1709938 PMID:2538475 PMID:2974285 RGD:69857 RGD:729148 RGD:8553840 NCBI chr2B:103,893,724...103,925,318 JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:9346943 RGD:1626111 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 enables ISO binds with high affinity
(PMID:15308688)
RGD
CAFA
PMID:7689963 PMID:15308688 RGD:2301726 NCBI chr12:35,654,172...35,659,115
Ensembl chr12:36,435,221...36,440,132
JBrowse link
G INSR insulin receptor enables ISO (PMID:12138094) BHF-UCL PMID:12138094 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
interleukin-1 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAX1 HCLS1 associated protein X-1 enables ISO (PMID:11554782) UniProt PMID:11554782 NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO (MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:5468848 Ensembl chr2A:103,193,131...103,230,005 JBrowse link
G IL1R2 interleukin 1 receptor type 2 ISO (MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:5468848 Ensembl chr2A:103,042,328...103,078,190 JBrowse link
G IL1RAPL1 interleukin 1 receptor accessory protein like 1 NOT|enables ISO (PMID:12783849) UniProt PMID:12783849 NCBI chr  X:21,180,693...22,548,122
Ensembl chr  X:28,950,521...30,109,286
JBrowse link
G NLRP7 NLR family pyrin domain containing 7 enables ISO (PMID:15817483) UniProt PMID:15817483 NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844
JBrowse link
G TRIM16 tripartite motif containing 16 enables ISO (PMID:16575408) UniProt PMID:16575408 NCBI chr17:35,973,775...36,028,767 JBrowse link
interleukin-1 receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100991079 interleukin-1 receptor antagonist protein enables ISO (PMID:2137200), (PMID:2139180) BHF-UCL PMID:2137200 PMID:2139180 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
interleukin-1 type I receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100991079 interleukin-1 receptor antagonist protein enables ISO (PMID:1828071) BHF-UCL PMID:1828071 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
interleukin-1 type II receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100991079 interleukin-1 receptor antagonist protein enables ISO (PMID:1830582) BHF-UCL PMID:1830582 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
interleukin-10 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10RA interleukin 10 receptor subunit alpha ISO RGD PMID:12405978 PMID:19428551 RGD:2311043 RGD:729323 NCBI chr11:112,820,445...112,835,603
Ensembl chr11:116,752,619...116,767,771
JBrowse link
interleukin-11 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL11RA interleukin 11 receptor subunit alpha ISO (MGI:69257|PMID:7957045) MGI PMID:7957045 MGI:69257 NCBI chr 9:34,487,313...34,498,477 JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer contributes_to ISO (MGI:69257|PMID:7957045) MGI PMID:7957045 MGI:69257 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817
JBrowse link
interleukin-2 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2RA interleukin 2 receptor subunit alpha ISO (MGI:64265|PMID:8262055) MGI PMID:8262055 MGI:64265 NCBI chr10:6,053,549...6,103,863 JBrowse link
G IL2RB interleukin 2 receptor subunit beta enables ISO (PMID:2467293), (PMID:31040184), (PMID:31040185)
(MGI:64265|PMID:8262055)
RGD
UniProt
MGI
PMID:1469024 PMID:2467293 PMID:8262055 PMID:31040184 PMID:31040185 MGI:64265 RGD:2303496 NCBI chr22:18,039,469...18,069,952
Ensembl chr22:35,874,898...35,899,038
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma ISO (MGI:64265|PMID:8262055) MGI PMID:8262055 MGI:64265 NCBI chr  X:60,375,815...60,386,936 JBrowse link
interleukin-6 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6R interleukin 6 receptor enables ISO (MGI:50330|PMID:1312474)
(PMID:12829785)
MGI
BHF-UCL
PMID:1312474 PMID:12829785 MGI:50330 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer contributes_to ISO (PMID:12829785) BHF-UCL PMID:12829785 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817
JBrowse link
interleukin-9 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100991889 interleukin-9 receptor ISO RGD PMID:7966560 RGD:633086 NCBI chr 9:109,268,011...109,277,418
Ensembl chr  X:155,373,324...155,386,631
JBrowse link
nerve growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme enables ISO (PMID:8615794) BHF-UCL PMID:8615794 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023
JBrowse link
G NGFR nerve growth factor receptor ISO (MGI:1098517|PMID:1317267) RGD
MGI
PMID:1317267 PMID:3027580 MGI:1098517 RGD:728964 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NTF3 neurotrophin 3 ISO RGD PMID:2164684 RGD:729140 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 enables ISO (PMID:8615794) BHF-UCL PMID:8615794 NCBI chr15:80,029,225...80,226,027
Ensembl chr15:99,312,512...99,460,444
JBrowse link
G SORT1 sortilin 1 enables ISO (PMID:14985763) BHF-UCL PMID:14985763 NCBI chr 1:111,687,119...111,775,339 JBrowse link
neuregulin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBB3 erb-b2 receptor tyrosine kinase 3 enables ISO (PMID:20682778) RGD
UniProt
PMID:14711829 PMID:20682778 RGD:2289958 NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994
JBrowse link
G ITGA6 integrin subunit alpha 6 enables ISO (PMID:20682778) UniProt PMID:20682778 NCBI chr2B:59,714,348...59,794,762
Ensembl chr2B:177,169,536...177,250,143
JBrowse link
G ITGAV integrin subunit alpha V contributes_to ISO (PMID:20682778) UniProtKB PMID:20682778 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028
JBrowse link
G ITGB3 integrin subunit beta 3 contributes_to ISO (PMID:20682778) UniProtKB PMID:20682778 NCBI chr17:10,134,450...10,194,596 JBrowse link
G ITGB4 integrin subunit beta 4 contributes_to ISO (PMID:20682778) UniProtKB PMID:20682778 NCBI chr17:69,671,252...69,708,520
Ensembl chr17:75,222,376...75,259,401
JBrowse link
neurotrophin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NGFR nerve growth factor receptor ISO RGD PMID:18596692 RGD:5508745 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 enables ISO PMID:1645620
(PMID:11738045)
(MGI:893826|PMID:1645620)
UniProt PMID:1645620 PMID:11738045 MGI:893826 RGD:8554777 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678
JBrowse link
platelet-derived growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
G COL1A2 collagen type I alpha 2 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803
JBrowse link
G COL2A1 collagen type II alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr12:40,726,137...40,757,690 JBrowse link
G COL3A1 collagen type III alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr2B:76,285,115...76,322,703
Ensembl chr2B:194,204,613...194,242,956
JBrowse link
G COL4A1 collagen type IV alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr13:91,282,617...91,440,187
Ensembl chr13:110,407,009...110,562,529
JBrowse link
G COL5A1 collagen type V alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr 9:105,746,388...105,956,280
Ensembl chr 9:134,342,955...134,544,651
JBrowse link
G COL6A1 collagen type VI alpha 1 chain enables ISO (PMID:8900172) MGI PMID:8900172 NCBI chr21:32,322,185...32,346,850
Ensembl chr21:45,584,096...45,607,240
JBrowse link
G PDGFA platelet derived growth factor subunit A enables ISO (PMID:7073684) BHF-UCL PMID:7073684 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B enables ISO (PMID:7073684) BHF-UCL PMID:7073684 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha enables ISO (MGI:3056973|PMID:15372073), (MGI:5294530|PMID:20110689)
(PMID:10806482)
(PMID:2536956)
(PMID:2554309), (PMID:8188664)
UniProt
BHF-UCL
PMID:2536956 PMID:2554309 PMID:8188664 PMID:10806482 PMID:15372073 PMID:20110689 MGI:3056973 MGI:5294530 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G PDGFRB platelet derived growth factor receptor beta enables ISO (PMID:2536956)
(PMID:2554309), (PMID:2850496)
BHF-UCL
UniProt
PMID:2536956 PMID:2554309 PMID:2850496 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
transforming growth factor beta binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 enables ISO (MGI:2181509|PMID:12054694)
(PMID:8242742)
MGI
UniProt
PMID:8242742 PMID:12054694 MGI:2181509 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G ACVR2B activin A receptor type 2B NOT ISO (MGI:51043|PMID:1326537) MGI PMID:1326537 MGI:51043 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
JBrowse link
G ACVRL1 activin A receptor like type 1 enables ISO (PMID:8242742) UniProt PMID:8242742 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691
JBrowse link
G AGRN agrin ISO RGD PMID:20505824 RGD:8549766 Ensembl chr 1:936,000...966,808 JBrowse link
G CD109 CD109 molecule enables ISO (PMID:16754747) UniProt PMID:16754747 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414
JBrowse link
G CD36 CD36 molecule enables ISO PMID:10487979 BHF-UCL PMID:10487979 RGD:2317966 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G ENG endoglin contributes_to
enables
ISO (PMID:9872992)
(PMID:1326540)
(PMID:1326540), (PMID:8370410)
(MGI:66318|PMID:8194490)
BHF-UCL PMID:1326540 PMID:8194490 PMID:8370410 PMID:9872992 MGI:66318 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G HYAL2 hyaluronidase 2 ISO (MGI:3851310|PMID:19366691) BHF-UCL PMID:19366691 MGI:3851310 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551
JBrowse link
G LRRC32 leucine rich repeat containing 32 enables ISO (MGI:5920420|PMID:28912269)
(PMID:22278742)
(PMID:19651619)
UniProt PMID:19651619 PMID:22278742 PMID:28912269 MGI:5920420 NCBI chr11:71,708,222...71,721,426
Ensembl chr11:75,354,997...75,367,440
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 enables ISO (PMID:10930463)
(PMID:10930463), (PMID:2022183), (PMID:8617200)
(PMID:10930463), (PMID:18672106), (PMID:2022183), (PMID:8617200)
UniProt PMID:2022183 PMID:8617200 PMID:10930463 PMID:18672106 NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 enables ISO (PMID:10930463), (PMID:18672106) UniProt PMID:10930463 PMID:18672106 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 enables ISO (PMID:9660815)
(PMID:10930463)
UniProt PMID:9660815 PMID:10930463 NCBI chr19:37,637,509...37,674,791
Ensembl chr19:46,144,485...46,181,636
JBrowse link
G NRROS negative regulator of reactive oxygen species enables ISO (MGI:6192878|PMID:29909984)
(PMID:29909984)
UniProt PMID:29909984 MGI:6192878 NCBI chr 3:193,984,797...194,007,173
Ensembl chr 3:203,920,334...203,948,506
JBrowse link
G TGFB3 transforming growth factor beta 3 enables ISO (PMID:18243111) BHF-UCL PMID:18243111 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 contributes_to
enables
ISO (PMID:11157754)
(PMID:14633705)
(PMID:1326540)
(MGI:3766844|PMID:17878231)
(PMID:1333888)
BHF-UCL
HGNC-UCL
MGI
RGD
PMID:1326540 PMID:1333888 PMID:8272871 PMID:11157754 PMID:14633705 PMID:17878231 MGI:3766844 RGD:737663 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 contributes_to
enables
ISO (PMID:11157754), (PMID:7852346)
(PMID:1333888)
(PMID:1326540), (PMID:1333888)
(PMID:11157754), (PMID:18243111), (PMID:18453574), (PMID:7852346)
(MGI:3766844|PMID:17878231)
BHF-UCL
MGI
PMID:1326540 PMID:1333888 PMID:7852346 PMID:11157754 PMID:17878231 PMID:18243111 PMID:18453574 MGI:3766844 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 contributes_to
enables
ISO PMID:8106553
(PMID:11157754)
PMID:7852346
(MGI:3699491|PMID:17295310)
(PMID:11157754), (PMID:12958365)
RGD
BHF-UCL
PMID:1657407 PMID:1744125 PMID:7852346 PMID:8106553 PMID:11157754 PMID:12958365 PMID:17295310 MGI:3699491 RGD:1579949 RGD:2302518 RGD:729942 RGD:8553463 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G THBS1 thrombospondin 1 ISO RGD PMID:10487979 RGD:2317966 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan ISO (MGI:5449316|PMID:22995554) UniProt PMID:22995554 MGI:5449316 NCBI chr11:71,833,654...71,848,509
Ensembl chr11:75,492,912...75,493,973
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 enables ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr18:4,883,688...4,950,963
Ensembl chr18:7,164,091...7,229,271
JBrowse link
G VASN vasorin enables ISO (PMID:15247411) UniProt PMID:15247411 NCBI chr16:3,298,836...3,310,548
Ensembl chr16:4,475,506...4,477,527
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 enables ISO (PMID:21054789) UniProt PMID:21054789
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 enables ISO (PMID:21054789)
(PMID:12595574)
UniProt PMID:12595574 PMID:21054789 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569
JBrowse link
vascular endothelial growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDR kinase insert domain receptor enables ISO (PMID:20660291), (PMID:25825981) BHF-UCL PMID:20660291 PMID:25825981 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G NRP1 neuropilin 1 enables ISO (MGI:5562961|PMID:24401374)
(PMID:24401374)
BHF-UCL PMID:24401374 MGI:5562961 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha enables ISO (PMID:17470632) BHF-UCL PMID:17470632 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G PDGFRB platelet derived growth factor receptor beta enables ISO (PMID:17470632) BHF-UCL PMID:17470632 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PTN pleiotrophin ISO RGD PMID:17881084 RGD:2292001 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14980
    binding 14179
      protein binding 13741
        growth factor binding 119
          epidermal growth factor binding 3
          fibroblast growth factor binding 25
          hepatocyte growth factor binding 1
          insulin-like growth factor binding + 15
          interleukin-1 binding + 7
          interleukin-10 binding 1
          interleukin-11 binding 2
          interleukin-2 binding 3
          interleukin-3 binding 0
          interleukin-4 binding 0
          interleukin-5 binding 0
          interleukin-6 binding 2
          interleukin-7 binding 0
          interleukin-9 binding 1
          neuregulin binding 5
          neurotrophin binding + 8
          platelet-derived growth factor binding 11
          transforming growth factor beta binding 23
          vascular endothelial growth factor binding 5
paths to the root