ONTOLOGY REPORT - ANNOTATIONS
Term: ATPase-coupled monoatomic cation transmembrane transporter activity
Accession: GO:0019829
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Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
Synonyms: exact_synonym: ATP-dependent cation transmembrane transporter activity; cation-transporting ATPase activity
narrow_synonym: cation ABC transporter; plasma membrane cation-transporting ATPase
broad_synonym: ATPase-coupled cation transmembrane transporter activity
xref: reactome:R-HSA-5251989 "ATP13A4,5 transport divalent ions from extracellular region to cytosol"; reactome:R-HSA-5692480 "ATP13A2 transports cations from cytosol to lysosomal lumen"
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Abcc8
ATP-binding cassette, sub-family C member 8
enables
ISO
GO_Central
GO_REF:0000119
NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457
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Abcc9
ATP-binding cassette, sub-family C member 9
enables
ISO
GO_Central
GO_REF:0000096
NCBI chr 6:142,533,592...142,648,472
Ensembl chr 6:142,533,588...142,648,041
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Atp13a1
ATPase type 13A1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 8:70,243,813...70,260,399
Ensembl chr 8:70,243,813...70,260,399
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Atp13a2
ATPase type 13A2
enables
IBA IEA
GO_Central InterPro
GO_REF:0000002 GO_REF:0000033
NCBI chr 4:140,711,812...140,734,641
Ensembl chr 4:140,714,184...140,734,641
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Atp13a3
ATPase type 13A3
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr16:30,131,241...30,207,674
Ensembl chr16:30,131,241...30,224,793
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Atp13a4
ATPase type 13A4
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr16:29,208,685...29,363,682
Ensembl chr16:29,214,671...29,363,682
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Atp13a5
ATPase type 13A5
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr16:29,049,242...29,208,807
Ensembl chr16:29,050,603...29,197,550
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Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
enables
ISO
RGD GO_Central
PMID:12529322
GO_REF:0000096 GO_REF:0000119 RGD:1299865
NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
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Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
enables
ISO
GO_Central
GO_REF:0000119
NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
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Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
enables
ISO IEA
GO_Central Ensembl
GO_REF:0000096 GO_REF:0000107
NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188
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Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
enables
IEA ISO
Ensembl GO_Central
GO_REF:0000096 GO_REF:0000107
NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340
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Anxa5
annexin A5
enables
ISO
RGD GO_Central
PMID:9299392
GO_REF:0000096 RGD:10053703
NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
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Atp13a4
ATPase type 13A4
enables
IC
(PMID:19731010)
MGI
PMID:19731010
NCBI chr16:29,208,685...29,363,682
Ensembl chr16:29,214,671...29,363,682
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Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
enables
ISO IBA ISS
RGD GO_Central UniProt MGI
PMID:12222829 PMID:12409282
GO_REF:0000008 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:724593 RGD:727704
NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
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Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
enables
ISO IDA IMP
(PMID:12756243), (PMID:9887021) (PMID:29475982), (PMID:31819041)
RGD GO_Central MGI
PMID:9887021 PMID:12409282 PMID:12756243 PMID:21300842 PMID:29475982 PMID:31819041 More...
GO_REF:0000096 GO_REF:0000119 RGD:6904139 RGD:724593
NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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Atp2a3
ATPase, Ca++ transporting, ubiquitous
enables
ISO IBA IEA
GO_Central UniProt RHEA
GO_REF:0000003 GO_REF:0000033 GO_REF:0000096 GO_REF:0000116 GO_REF:0000119
NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
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Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
enables
IEA IBA
UniProt GO_Central RHEA
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116
NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
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Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
enables
ISO IBA ISS TAS
RGD GO_Central UniProt Reactome
PMID:2837461
GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:631720 Reactome:R-MMU-9668464
NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
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Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr X:72,546,356...72,632,267
Ensembl chr X:72,546,692...72,614,611
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Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
enables
ISO IBA IEA
RGD GO_Central RHEA UniProt
PMID:11779484
GO_REF:0000003 GO_REF:0000033 GO_REF:0000096 GO_REF:0000116 GO_REF:0000119 RGD:628395
NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779
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Atp2c1
ATPase, Ca++-sequestering
NOT|enables
ISO IBA ISS TAS
(PMID:16192278) (PMID:10951186)
UniProt GO_Central UniProt MGI RGD
PMID:10951186 PMID:15328051 PMID:16192278 PMID:19527224
GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1581800 RGD:7241224
NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518
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Atp2c2
ATPase, Ca++ transporting, type 2C, member 2
enables
ISO IBA ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119
NCBI chr 8:120,426,748...120,484,457
Ensembl chr 8:120,426,748...120,484,456
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Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
enables
ISS IBA ISO
UniProt GO_Central
GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119
NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
enables
ISO
GO_Central
GO_REF:0000119
NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
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Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
enables
ISO
GO_Central
GO_REF:0000119
NCBI chr X:72,546,356...72,632,267
Ensembl chr X:72,546,692...72,614,611
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Atp7a
ATPase, copper transporting, alpha polypeptide
enables
IDA IBA
(PMID:15634671)
MGI GO_Central
PMID:15634671
GO_REF:0000033
NCBI chr X:105,070,830...105,171,766
Ensembl chr X:105,070,882...105,168,532
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Atp7b
ATPase, copper transporting, beta polypeptide
enables
IDA IBA ISO IMP
(PMID:11237756), (PMID:15634671)
MGI GO_Central
PMID:11237756 PMID:15634671
GO_REF:0000033 GO_REF:0000119
NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
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Tmem94
transmembrane protein 94
enables
ISO IBA IDA
(PMID:38513662)
GO_Central UniProt
PMID:38513662
GO_REF:0000033 GO_REF:0000119
NCBI chr11:115,656,245...115,689,859
Ensembl chr11:115,656,259...115,690,192
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Atp2c1
ATPase, Ca++-sequestering
enables
ISO ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000119
NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518
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Atp2c2
ATPase, Ca++ transporting, type 2C, member 2
enables
IEA ISO
RHEA GO_Central
GO_REF:0000116 GO_REF:0000119
NCBI chr 8:120,426,748...120,484,457
Ensembl chr 8:120,426,748...120,484,456
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Atp7a
ATPase, copper transporting, alpha polypeptide
enables
ISS ISO
UniProt GO_Central
GO_REF:0000024 GO_REF:0000119
NCBI chr X:105,070,830...105,171,766
Ensembl chr X:105,070,882...105,168,532
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Atp7b
ATPase, copper transporting, beta polypeptide
enables
IEA
UniProt RHEA
GO_REF:0000003 GO_REF:0000116
NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
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Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
enables
IDA
(PMID:23229519)
UniProt
PMID:23229519
NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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Atp12a
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
enables contributes_to
ISO ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000096 GO_REF:0000119
NCBI chr14:56,602,525...56,626,008
Ensembl chr14:56,602,525...56,626,007
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Atp4a
ATPase, H+/K+ exchanging, gastric, alpha polypeptide
enables
IBA IDA
(PMID:7762614)
GO_Central MGI
PMID:7762614
GO_REF:0000033
NCBI chr 7:30,411,634...30,424,959
Ensembl chr 7:30,411,634...30,424,959
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Atp4b
ATPase, H+/K+ exchanging, beta polypeptide
enables
ISO
(PMID:7762614)
MGI
PMID:7762614
NCBI chr 8:13,436,209...13,446,778
Ensembl chr 8:13,436,205...13,446,825
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Atp5f1e
ATP synthase F1 subunit epsilon
enables
ISA
(PMID:10727396)
MGI
PMID:10727396
NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898
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Atp5mg
ATP synthase membrane subunit g
enables
ISO
(PMID:10361692)
MGI
PMID:10361692
NCBI chr 9:44,824,546...44,832,470
Ensembl chr 9:44,823,855...44,832,040
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Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
enables
ISA
(PMID:11498539)
MGI
PMID:11498539
NCBI chr 6:38,025,418...38,101,521
Ensembl chr 6:38,025,418...38,101,521
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Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
enables
ISA
(PMID:11441017)
MGI
PMID:11441017
NCBI chr 4:117,741,523...117,744,548
Ensembl chr 4:117,741,523...117,744,530
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Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C
enables
ISA
(PMID:11441017)
MGI
PMID:11441017
NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676
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Atp12a
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
enables
ISO IBA ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119
NCBI chr14:56,602,525...56,626,008
Ensembl chr14:56,602,525...56,626,007
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Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
enables
ISO IBA IMP IDA
(PMID:10360172), (PMID:15485817) (PMID:23229519)
RGD GO_Central MGI
PMID:10360172 PMID:12531906 PMID:15485817 PMID:16624992 PMID:16893515 PMID:23229519 More...
GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1581763 RGD:2302992 RGD:629542
NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
enables
ISO IBA ISS
RGD GO_Central UniProt
PMID:16624992
GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:2302992
NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
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Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
enables
IDA IBA ISO ISS
(PMID:19666602), (PMID:21418141)
MGI GO_Central UniProt
PMID:19666602 PMID:21418141
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119
NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
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Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
enables
IMP IBA ISO IDA
(PMID:21187400) (PMID:23229519)
MGI GO_Central
PMID:21187400 PMID:23229519
GO_REF:0000008 GO_REF:0000033 GO_REF:0000119
NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
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Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
enables
ISO IEA
RGD GO_Central Ensembl
PMID:16624992
GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 RGD:2302992
NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
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Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
enables
ISO
RGD GO_Central
PMID:12562669
GO_REF:0000096 RGD:631758
NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768
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Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
enables
ISO
RGD GO_Central
PMID:12562669 PMID:16624992
GO_REF:0000096 RGD:2302992 RGD:631758
NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
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Atp4a
ATPase, H+/K+ exchanging, gastric, alpha polypeptide
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:30,411,634...30,424,959
Ensembl chr 7:30,411,634...30,424,959
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Cpox
coproporphyrinogen oxidase
enables
TAS
(PMID:12470976)
MGI
PMID:12470976
NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
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Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
enables
IGI
(PMID:19376779)
BHF-UCL
PMID:19376779
NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
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Atp5f1b
ATP synthase F1 subunit beta
enables
IEA ISO
UniProt GO_Central
GO_REF:0000003 GO_REF:0000119
NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
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Atp6v0a1
ATPase, H+ transporting, lysosomal V0 subunit A1
enables
IEA
InterPro
GO_REF:0000002
NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545
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Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 5:124,767,117...124,801,519
Ensembl chr 5:124,766,641...124,801,519
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Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 6:38,025,418...38,101,521
Ensembl chr 6:38,025,418...38,101,521
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Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 4:117,741,523...117,744,548
Ensembl chr 4:117,741,523...117,744,530
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Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C
enables
IEA
InterPro
GO_REF:0000002
NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676
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Atp6v0d1
ATPase, H+ transporting, lysosomal V0 subunit D1
contributes_to
IDA
(PMID:12527205)
MGI
PMID:12527205
NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679
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Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 4:19,876,838...19,922,566
Ensembl chr 4:19,876,841...19,922,605
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Atp6v0e
ATPase, H+ transporting, lysosomal V0 subunit E
enables
ISO IEA
GO_Central InterPro
GO_REF:0000002 GO_REF:0000119
NCBI chr17:26,895,370...26,918,621
Ensembl chr17:26,882,205...26,918,621
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Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
enables
ISO IEA
GO_Central InterPro
GO_REF:0000002 GO_REF:0000119
NCBI chr 6:48,514,503...48,518,735
Ensembl chr 6:48,514,549...48,518,735
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Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
enables
IMP IBA
(PMID:23863464)
UniProt GO_Central
PMID:23863464
GO_REF:0000033
NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
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Atp6v1b1
ATPase, H+ transporting, lysosomal V1 subunit B1
enables
IBA IEA
GO_Central InterPro
GO_REF:0000002 GO_REF:0000033
NCBI chr 6:83,719,999...83,735,837
Ensembl chr 6:83,719,972...83,735,837
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Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
enables
IBA IEA
GO_Central InterPro
GO_REF:0000002 GO_REF:0000033
NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
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Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
enables
IDA IBA
(PMID:12527205)
MGI GO_Central
PMID:12527205
GO_REF:0000033
NCBI chr15:38,662,096...38,692,688
Ensembl chr15:38,662,177...38,692,690
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Atp6v1c2
ATPase, H+ transporting, lysosomal V1 subunit C2
enables
IBA IDA
(PMID:12527205)
GO_Central MGI
PMID:12527205
GO_REF:0000033
NCBI chr12:17,334,722...17,375,700
Ensembl chr12:17,334,722...17,379,360
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Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
enables
IEA
InterPro
GO_REF:0000002
NCBI chr12:78,889,756...78,908,810
Ensembl chr12:78,887,499...78,908,412
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Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
enables
IGI IBA
(PMID:11872743)
MGI GO_Central
PMID:11872743
GO_REF:0000033
NCBI chr 6:120,772,205...120,799,659
Ensembl chr 6:120,771,266...120,799,754
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Atp6v1e2
ATPase, H+ transporting, lysosomal V1 subunit E2
enables
IGI IBA
(PMID:11872743)
MGI GO_Central
PMID:11872743
GO_REF:0000033
NCBI chr17:87,251,537...87,255,315
Ensembl chr17:87,251,537...87,255,325
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Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 6:29,467,782...29,470,508
Ensembl chr 6:29,467,717...29,470,511
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Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
enables
IDA IBA
(PMID:12527205)
MGI GO_Central
PMID:12527205
GO_REF:0000033
NCBI chr 4:63,463,002...63,468,938
Ensembl chr 4:63,463,009...63,468,987
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Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
enables
IDA IBA
(PMID:12527205)
MGI GO_Central
PMID:12527205
GO_REF:0000033
NCBI chr17:35,453,910...35,457,743
Ensembl chr17:35,452,636...35,457,743
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Atp6v1g3
ATPase, H+ transporting, lysosomal V1 subunit G3
enables
IDA IBA
(PMID:12527205)
MGI GO_Central
PMID:12527205
GO_REF:0000033
NCBI chr 1:138,201,476...138,217,200
Ensembl chr 1:138,201,476...138,217,200
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Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 1:5,153,201...5,233,438
Ensembl chr 1:5,140,241...5,232,752
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all