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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin complex
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Accession:GO:0019814 term browser browse the term
Definition:A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment:Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
Synonyms:narrow_synonym: antibody


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B cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79a CD79a molecule part_of IBA
ISO
PMID:21873635
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
RGD PMID:1373499 PMID:8626447 PMID:21873635 MGI:3521842 MGI:79455, RGD:13792537 NCBI chr 1:80,493,520...80,497,936
Ensembl chr 1:80,493,581...80,497,935
JBrowse link
G Cd79b CD79b molecule part_of IBA
ISO
PMID:21873635
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
RGD PMID:1373499 PMID:8626447 PMID:21873635 MGI:3521842 MGI:79455, RGD:13792537 NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625
JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 part_of IBA
ISO
PMID:21873635
(MGI:3769059|PMID:16249387)
RGD PMID:16249387 PMID:21873635 MGI:3769059, RGD:13792537 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127
JBrowse link
G Syk spleen associated tyrosine kinase part_of IEA
ISO
GO_REF:0000107
(MGI:79455|PMID:8626447)
Ensembl
RGD
PMID:8626447 GO_REF:0000107 MGI:79455 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
dimeric IgA immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jchain joining chain of multimeric IgA and IgM part_of ISO (PMID:17237408)
(MGI:5553246|PMID:17237408)
RGD PMID:17237408 MGI:5553246 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
hexameric IgM immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ighe immunoglobulin heavy constant epsilon part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ighm immunoglobulin heavy constant mu part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Jchain joining chain of multimeric IgA and IgM NOT|part_of ISO (PMID:21786026) RGD PMID:21786026 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
immunoglobulin complex, circulating term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034739.1 Ig lambda-2 chain C region part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:81,914,966...81,915,280 JBrowse link
G AABR07065640.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065643.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065645.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065645.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065651.8 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.10 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.8 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065656.9 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065673.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065676.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065680.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065684.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065688.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065693.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065693.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065693.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065699.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065699.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065699.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065699.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065699.5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065705.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065705.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065705.5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065705.6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065714.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065737.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065740.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065750.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065750.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065753.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065768.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065768.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065768.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065772.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065772.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065772.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065773.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065774.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065776.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065776.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065778.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065778.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065778.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065781.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065782.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:134,539,974...134,540,303 JBrowse link
G AABR07065789.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:134,872,774...134,873,270 JBrowse link
G AABR07065789.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065789.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065790.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:134,584,503...134,585,002 JBrowse link
G AABR07065792.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065792.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065798.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065802.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065804.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065808.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:135,178,938...135,179,469 JBrowse link
G AABR07065811.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065812.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065812.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:135,387,664...135,388,140 JBrowse link
G AABR07065813.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:135,538,767...135,568,573 JBrowse link
G AABR07065814.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065814.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:135,592,956...135,593,464 JBrowse link
G AABR07065814.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065814.4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065814.5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065814.7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065815.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065815.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065823.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:136,187,348...136,187,728 JBrowse link
G AABR07065823.2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:136,095,796...136,096,294 JBrowse link
G AABR07065823.3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065827.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065834.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065837.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065839.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065844.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065877.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065883.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065886.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07065889.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC109737.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:70,417,612...70,418,013 JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Igh-6 immunoglobulin heavy chain 6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ighe immunoglobulin heavy constant epsilon part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ighg1 immunoglobulin heavy constant gamma 1 part_of IBA
ISO
PMID:21873635
(MGI:1354084|PMID:10704460), (MGI:1889050|PMID:8418208), (MGI:1926579|PMID:11057672), (MGI:2153656|PMID:11714799), (MGI:2664488|PMID:11911824), (MGI:2670820|PMID:12882831), (MGI:2671681|PMID:9492004), (MGI:2679189|PMID:11911823), (MGI:2683928|PMID:6952213), (MGI:2684211|PMID:4098598), (MGI:3037416|PMID:14988498), (MGI:3039643|PMID:12867038), (MGI:3528786|PMID:15692051), (MGI:3620376|PMID:16492738), (MGI:3690573|PMID:9834074), (MGI:3695768|PMID:16275384), (MGI:62368|PMID:7688139), (MGI:67606|PMID:8041705), (MGI:67723|PMID:8047141), (MGI:77753|PMID:8566034), (MGI:78617|PMID:8552190)
RGD PMID:4098598 PMID:6952213 PMID:7688139 PMID:8041705 PMID:8047141 More... MGI:1354084 MGI:1889050 MGI:1926579 MGI:2153656 MGI:2664488 MGI:2670820 MGI:2671681 MGI:2679189 MGI:2683928 MGI:2684211 MGI:3037416 MGI:3039643 MGI:3528786 MGI:3620376 MGI:3690573 MGI:3695768 MGI:62368 MGI:67606 MGI:67723 MGI:77753 MGI:78617, RGD:13792537 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Ighm immunoglobulin heavy constant mu part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ighv1-58 immunoglobulin heavy variable 1-58 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Igkc immunoglobulin kappa constant part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Igll1 immunoglobulin lambda-like polypeptide 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:84,138,847...84,142,238
Ensembl chr11:84,138,910...84,142,216
JBrowse link
G LOC100359684 mCG114411-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:133,772,769...133,773,360 JBrowse link
G LOC100360628 rCG58847-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:133,227,058...133,628,143 JBrowse link
G LOC100360761 rCG64219-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:134,328,070...134,328,632 JBrowse link
G LOC100361105 Igh protein-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G LOC100361706 lambda-chain C1-region-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:81,947,966...81,949,822
Ensembl chr11:81,947,934...81,949,822
JBrowse link
G LOC362795 immunoglobulin G heavy chain part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G LOC691815 Ig heavy chain V region PJ14-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:134,068,429...134,068,900 JBrowse link
G RGD1564318 similar to immunoglobulin light chain variable region part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
monomeric IgA immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jchain joining chain of multimeric IgA and IgM part_of ISO (PMID:23250751) RGD PMID:23250751 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
pentameric IgM immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ighe immunoglobulin heavy constant epsilon part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ighm immunoglobulin heavy constant mu part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Jchain joining chain of multimeric IgA and IgM part_of IBA
ISO
PMID:21873635
(PMID:21786026), (PMID:23250751), (PMID:24145934)
RGD PMID:21786026 PMID:23250751 PMID:24145934 PMID:21873635 RGD:13792537 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
secretory dimeric IgA immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jchain joining chain of multimeric IgA and IgM part_of ISO (PMID:24145934) RGD PMID:24145934 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
secretory IgA immunoglobulin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jchain joining chain of multimeric IgA and IgM part_of ISO (PMID:23250751), (PMID:24145934), (PMID:32029686) RGD PMID:23250751 PMID:24145934 PMID:32029686 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
G Pigr polymeric immunoglobulin receptor part_of IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:32029686)
Ensembl
UniProt
RGD
PMID:32029686 GO_REF:0000024 GO_REF:0000107 NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20010
    protein-containing complex 6011
      immunoglobulin complex 118
        B cell receptor complex + 4
        IgA immunoglobulin complex + 2
        IgD immunoglobulin complex + 0
        IgE immunoglobulin complex + 0
        IgG immunoglobulin complex + 0
        IgM immunoglobulin complex + 3
        IgW immunoglobulin complex 0
        IgX immunoglobulin complex 0
        IgY immunoglobulin complex 0
        IgZ immunoglobulin complex 0
        heavy chain immunoglobulin complex 0
        immunoglobulin complex, circulating + 114
paths to the root