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ONTOLOGY REPORT - ANNOTATIONS


Term:polyol metabolic process
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Accession:GO:0019751 term browser browse the term
Definition:The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
Synonyms:exact_synonym: polyhydric alcohol metabolic process;   polyol metabolism



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polyol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B10 aldo-keto reductase family 1 member B10 ISO RGD PMID:20709016 RGD:6903952 NCBI chr 7:126,486,012...126,499,852
Ensembl chr 7:138,992,835...139,006,003
JBrowse link
calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in ISO (PMID:15465040) UniProt PMID:15465040 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
(MGI:3590419|PMID:15972816)
BHF-UCL
UniProt
PMID:9415400 PMID:15795327 PMID:15972816 PMID:16549446 PMID:17023519 More... MGI:3590419 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 involved_in ISO (PMID:15465040), (PMID:18511070) UniProt PMID:15465040 PMID:18511070 NCBI chr11:14,960,651...14,989,083
Ensembl chr11:14,656,939...14,671,584
JBrowse link
diol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:2507189 RGD:11252156 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
diphosphoinositol polyphosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT3 nudix hydrolase 3 involved_in ISO (PMID:10585413) UniProt PMID:10585413 NCBI chr 6:33,849,695...33,961,691
Ensembl chr 6:34,959,955...35,062,853
JBrowse link
galactitol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALK1 galactokinase 1 acts_upstream_of_or_within ISO (MGI:1861531|PMID:10915771) MGI PMID:10915771 MGI:1861531 NCBI chr17:69,708,641...69,715,942
Ensembl chr17:75,259,522...75,269,048
JBrowse link
gentamycin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC34A1 solute carrier family 34 member 1 ISO RGD PMID:11231357 RGD:7243145 NCBI chr 5:172,685,862...172,700,440
Ensembl chr 5:179,748,492...179,762,975
JBrowse link
glycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
ISO PMID:17545671
(MGI:3722000|PMID:17545671)
UniProt
MGI
PMID:17545671 MGI:3722000 RGD:8553472 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G LEP leptin ISO RGD PMID:21068181 RGD:5128556 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G PGP phosphoglycolate phosphatase involved_in ISO (PMID:26755581)
(MGI:5707518|PMID:26755581)
UniProt PMID:26755581 MGI:5707518 RGD:10679995 NCBI chr16:1,070,291...1,073,123 JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within
ISO PMID:4186849
(MGI:2157262|PMID:11792850)
BHF-UCL
MGI
PMID:4186849 PMID:11792850 MGI:2157262 RGD:8553288 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920
JBrowse link
glycerol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPTL3 angiopoietin like 3 involved_in ISO (PMID:12565906) BHF-UCL PMID:12565906 NCBI chr 1:61,855,870...61,863,476
Ensembl chr 1:63,670,516...63,679,194
JBrowse link
G COQ2 coenzyme Q2, polyprenyltransferase involved_in ISO (PMID:15153069) UniProt PMID:15153069 NCBI chr 4:40,913,015...40,934,594
Ensembl chr 4:46,762,659...46,784,014
JBrowse link
G COQ3 coenzyme Q3, methyltransferase involved_in ISO (PMID:10777520) UniProt PMID:10777520 NCBI chr 6:97,210,293...97,235,234
Ensembl chr 6:101,092,782...101,117,485
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5548046|PMID:24177035) MGI PMID:24177035 MGI:5548046 NCBI chr2A:71,495,573...71,730,073
Ensembl chr2A:72,994,888...73,228,846
JBrowse link
G GK glycerol kinase involved_in
acts_upstream_of_or_within
ISO (PMID:8499898)
(MGI:1097749|PMID:9302256), (MGI:3587535|PMID:16105550), (MGI:5051890|PMID:21536471)
BHF-UCL
MGI
PMID:8499898 PMID:9302256 PMID:16105550 PMID:21536471 MGI:1097749 MGI:3587535 MGI:5051890 NCBI chr  X:23,250,290...23,327,373
Ensembl chr  X:30,806,950...30,877,131
JBrowse link
G MYOF myoferlin acts_upstream_of_or_within ISO (MGI:5548046|PMID:24177035) MGI PMID:24177035 MGI:5548046 NCBI chr10:90,050,062...90,225,718
Ensembl chr10:93,561,190...93,735,979
JBrowse link
inositol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIOX myo-inositol oxygenase involved_in ISO (PMID:18364358)
(PMID:11716759)
UniProt PMID:11716759 PMID:18364358 NCBI chr22:30,735,206...30,738,738
Ensembl chr22:49,720,339...49,724,370
JBrowse link
inositol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPKA inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO (MGI:1314771|PMID:10454357) MGI PMID:10454357 MGI:1314771 NCBI chr15:20,434,532...20,444,389
Ensembl chr15:38,675,600...38,684,779
JBrowse link
G MECP2 methyl-CpG binding protein 2 acts_upstream_of_or_within ISO (MGI:3769075|PMID:17237885) MGI PMID:17237885 MGI:3769075 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MRPS6 mitochondrial ribosomal protein S6 acts_upstream_of_or_within ISO (MGI:3654617|PMID:16644257), (MGI:3812279|PMID:18675571) MGI PMID:16644257 PMID:18675571 MGI:3654617 MGI:3812279 NCBI chr21:20,441,365...20,510,800
Ensembl chr21:33,862,033...33,879,670
JBrowse link
G PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 involved_in ISO (PMID:17412958) UniProt PMID:17412958 NCBI chr15:22,495,159...22,553,264 JBrowse link
inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 involved_in ISO (PMID:20011604) DFLAT PMID:20011604 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G IP6K3 inositol hexakisphosphate kinase 3 acts_upstream_of_or_within ISO (PMID:11502751) MGI PMID:11502751 NCBI chr 6:33,294,835...33,320,117
Ensembl chr 6:34,403,261...34,428,386
JBrowse link
G IPMK inositol polyphosphate multikinase acts_upstream_of_or_within ISO (MGI:3583505|PMID:15939867) MGI PMID:15939867 MGI:3583505 NCBI chr10:54,718,987...54,799,264
Ensembl chr10:56,939,012...57,019,101
JBrowse link
inositol phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NTSR1 neurotensin receptor 1 ISO RGD PMID:15707678 RGD:9743914 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056
JBrowse link
inositol phosphate dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IMPA1 inositol monophosphatase 1 involved_in
acts_upstream_of_or_within
ISO PMID:9462881
(PMID:17068342)
(PMID:9462881)
UniProt
MGI
PMID:9462881 PMID:17068342 RGD:2302240 NCBI chr 8:78,177,200...78,209,901
Ensembl chr 8:79,800,257...79,829,935
JBrowse link
G IMPA2 inositol monophosphatase 2 acts_upstream_of_or_within ISO (PMID:17068342) MGI PMID:17068342 NCBI chr18:2,293,788...2,344,422
Ensembl chr18:4,557,280...4,608,991
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO PMID:9295334 MGI PMID:9295334 RGD:633135 NCBI chr 4:134,405,934...135,213,851
Ensembl chr 4:145,706,307...146,141,029
JBrowse link
G INPP5A inositol polyphosphate-5-phosphatase A acts_upstream_of_or_within ISO (PMID:8006039) MGI PMID:8006039 Ensembl chr10:133,437,718...133,681,116 JBrowse link
G INPP5E inositol polyphosphate-5-phosphatase E acts_upstream_of_or_within ISO (MGI:1861829|PMID:10806194) MGI PMID:10806194 MGI:1861829 NCBI chr 9:107,502,838...107,516,325
Ensembl chr 9:136,483,144...136,492,731
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K acts_upstream_of_or_within ISO (PMID:12536145) MGI PMID:12536145 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G MTMR2 myotubularin related protein 2 acts_upstream_of_or_within ISO (MGI:3619505|PMID:16399794) MGI PMID:16399794 MGI:3619505 NCBI chr11:90,839,577...90,929,731
Ensembl chr11:94,367,038...94,457,138
JBrowse link
G MTMR7 myotubularin related protein 7 acts_upstream_of_or_within ISO (MGI:2673068|PMID:12890864) MGI PMID:12890864 MGI:2673068 NCBI chr 8:16,509,712...16,626,018
Ensembl chr 8:13,454,694...13,571,706
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:9593664) UniProt PMID:9593664 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G SYNJ1 synaptojanin 1 acts_upstream_of_or_within ISO (MGI:1346710|PMID:10535736) MGI PMID:10535736 MGI:1346710 NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994
JBrowse link
G SYNJ2 synaptojanin 2 ISO RGD PMID:9388224 RGD:69390 NCBI chr 6:155,881,818...156,011,416
Ensembl chr 6:157,940,179...158,055,662
JBrowse link
inositol phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALR2 galanin receptor 2 ISO RGD PMID:9427506 RGD:69840 NCBI chr17:70,019,383...70,028,689
Ensembl chr17:75,578,072...75,580,806
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:17573483 RGD:5685371 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560
JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B ISO RGD PMID:1331748 RGD:9727450 NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591
JBrowse link
G IP6K2 inositol hexakisphosphate kinase 2 involved_in ISO (PMID:30624931) UniProt PMID:30624931 NCBI chr 3:48,608,902...48,638,185
Ensembl chr 3:49,690,486...49,719,798
JBrowse link
inositol phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IPPK inositol-pentakisphosphate 2-kinase involved_in ISO (PMID:12084730) BHF-UCL PMID:12084730 NCBI chr 9:63,737,324...63,793,348
Ensembl chr 9:91,808,757...91,864,773
JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG1 phospholipase C gamma 1 ISO RGD PMID:16973916 RGD:2299886 NCBI chr20:37,477,077...37,515,854
Ensembl chr20:38,572,709...38,615,145
JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:85738 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G PTAFR platelet activating factor receptor acts_upstream_of_or_within ISO (MGI:85738|PMID:9013981) MGI PMID:9013981 MGI:85738 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861
JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:12641450) UniProt PMID:12641450 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939
JBrowse link
inositol trisphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846
JBrowse link
G IPMK inositol polyphosphate multikinase involved_in ISO (PMID:30624931) UniProt PMID:30624931 NCBI chr10:54,718,987...54,799,264
Ensembl chr10:56,939,012...57,019,101
JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in ISO (PMID:1654894) UniProt PMID:1654894 NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678
JBrowse link
G PLCB1 phospholipase C beta 1 ISO RGD PMID:8387502 RGD:11535163 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019
JBrowse link
G PLCB3 phospholipase C beta 3 ISO RGD PMID:8387502 RGD:11535163 NCBI chr11:59,608,651...59,626,289
Ensembl chr11:62,953,587...62,971,393
JBrowse link
L-xylitol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase involved_in ISO (PMID:8487505) UniProt PMID:8487505 NCBI chr15:23,971,017...24,025,043 JBrowse link
L-xylitol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase involved_in ISO (PMID:3365415) UniProt PMID:3365415 NCBI chr15:23,971,017...24,025,043 JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLEK pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) BHF-UCL PMID:7559487 PMID:7782310 NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:7535379 RGD:7777104 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER3 alkaline ceramidase 3 involved_in ISO (PMID:11356846), (PMID:20068046) UniProt PMID:11356846 PMID:20068046 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586
JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1R1 ADCYAP receptor type I ISO RGD PMID:8943280 RGD:2315982 NCBI chr 7:31,597,251...31,724,299
Ensembl chr 7:31,784,622...31,843,381
JBrowse link
G AVPR1B arginine vasopressin receptor 1B involved_in ISO (PMID:9322919) ARUK-UCL PMID:9322919 NCBI chr 1:181,713,548...181,723,645
Ensembl chr 1:185,999,627...186,007,043
JBrowse link
G CD244 CD244 molecule involved_in ISO (PMID:8376943) UniProt PMID:8376943 NCBI chr 1:136,186,906...136,219,669
Ensembl chr 1:140,110,808...140,123,065
JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:1332507 RGD:2316794 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393
JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:11861328 RGD:9743897 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056
JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:8798508 RGD:9999203 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861
JBrowse link
G PTH parathyroid hormone involved_in ISO (PMID:11604398) CAFA PMID:11604398 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G PTH1R parathyroid hormone 1 receptor involved_in ISO PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 3:46,777,945...46,804,039
Ensembl chr 3:47,894,901...47,905,431
JBrowse link
G SNCA synuclein alpha involved_in ISO (PMID:15641770) UniProt PMID:15641770 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in ISO (MGI:5318037|PMID:10493819) BHF-UCL PMID:10493819 MGI:5318037 NCBI chr2A:48,808,822...48,879,021 JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 involved_in ISO (PMID:15705806) UniProt PMID:15705806 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618
JBrowse link
G P2RY1 purinergic receptor P2Y1 involved_in ISO PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813
JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:8670200) ARUK-UCL PMID:8670200 NCBI chr11:68,341,722...68,375,923
Ensembl chr11:71,594,250...71,595,236
JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:16709602 RGD:2300424 NCBI chr 3:37,906,359...37,928,564
Ensembl chr 3:38,189,496...38,206,886
JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:2135699|PMID:11371619) MGI PMID:11371619 MGI:2135699 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTK2B protein tyrosine kinase 2 beta involved_in ISO (MGI:3583523|PMID:12960403) UniProt PMID:12960403 MGI:3583523 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
sorbitol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B ISO RGD PMID:6690344 PMID:21376710 RGD:1626096 RGD:8548687 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095
JBrowse link
sorbitol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase involved_in ISO (PMID:32367058)
(PMID:12962626), (PMID:3365415), (PMID:6870831), (PMID:8487505)
FlyBase
UniProt
PMID:3365415 PMID:6870831 PMID:8487505 PMID:12962626 PMID:32367058 NCBI chr15:23,971,017...24,025,043 JBrowse link
sorbitol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase acts_upstream_of_or_within ISO (MGI:55679|PMID:6626150), (MGI:60299|PMID:722274) MGI PMID:722274 PMID:6626150 MGI:55679 MGI:60299 NCBI chr15:23,971,017...24,025,043 JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (MGI:3846467|PMID:19416652) MGI PMID:19416652 MGI:3846467 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (MGI:1098386|PMID:9363775) MGI PMID:9363775 MGI:1098386 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663
JBrowse link
sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEGS2 delta 4-desaturase, sphingolipid 2 acts_upstream_of_or_within ISO (MGI:3694278|PMID:16571104)
(MGI:3505861|PMID:11937514)
MGI PMID:11937514 PMID:16571104 MGI:3505861 MGI:3694278 NCBI chr14:80,767,334...80,813,506
Ensembl chr14:100,086,782...100,100,741
JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect ISO (PMID:26510981) ARUK-UCL PMID:26510981 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G ACER1 alkaline ceramidase 1 involved_in ISO (PMID:20207939)
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)
(PMID:17713573), (PMID:20628055)
UniProt
BHF-UCL
PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 MGI:5800647 MGI:6107252 NCBI chr19:5,327,251...5,393,587
Ensembl chr19:6,252,300...6,281,016
JBrowse link
G ACER2 alkaline ceramidase 2 involved_in ISO (PMID:20207939)
(MGI:6116621|PMID:29401619)
(PMID:16940153), (PMID:20089856), (PMID:20628055)
UniProt PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 MGI:6116621 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896
JBrowse link
G ACER3 alkaline ceramidase 3 involved_in ISO (PMID:20068046)
(MGI:5749603|PMID:26474409)
(PMID:20207939), (PMID:26792856)
UniProt PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586
JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12815059)
(MGI:1267186|PMID:9653654)
(PMID:10610716)
UniProt PMID:9653654 PMID:10610716 PMID:12815059 MGI:1267186 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in ISO PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386)
(MGI:6275120|PMID:10652340)
PMID:15217782
(PMID:30154232)
PMID:10488143
UniProt PMID:10488143 PMID:10652340 PMID:15123644 PMID:15217782 PMID:16126722 More... MGI:3608219 MGI:3640407 MGI:6275120 RGD:13838793 RGD:13838794 RGD:13838800 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336
JBrowse link
G SPHK1 sphingosine kinase 1 involved_in ISO (PMID:23106337) UniProt PMID:23106337 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in ISO (PMID:23106337) UniProt PMID:23106337 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767
JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (MGI:3814228|PMID:16216550) MGI PMID:16216550 MGI:3814228 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (MGI:3814228|PMID:16216550) MGI PMID:16216550 MGI:3814228 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663
JBrowse link
sphingosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100985247 putative inactive neutral ceramidase B involved_in ISO (PMID:16229686), (PMID:17475390), (PMID:26190575)
(PMID:10781606), (PMID:15946935)
UniProt PMID:10781606 PMID:15946935 PMID:16229686 PMID:17475390 PMID:26190575 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336
JBrowse link
G NAAA N-acylethanolamine acid amidase involved_in ISO (PMID:15655246) UniProt PMID:15655246 NCBI chr 4:48,264,567...48,294,872
Ensembl chr 4:54,102,384...54,128,776
JBrowse link
G PLPP1 phospholipid phosphatase 1 involved_in ISO (PMID:9705349)
(MGI:6383560|PMID:10359651)
PMID:8663293
UniProt PMID:8663293 PMID:9705349 PMID:10359651 MGI:6383560 RGD:15090855 RGD:15090857 NCBI chr 5:58,495,348...58,605,309
Ensembl chr 5:60,160,274...60,227,806
JBrowse link
G PLPP3 phospholipid phosphatase 3 involved_in ISO (PMID:9305923), (PMID:9705349) UniProt PMID:9305923 PMID:9705349 NCBI chr 1:55,779,343...55,862,717
Ensembl chr 1:57,489,178...57,573,398
JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within ISO (MGI:2176350|PMID:11756451) MGI PMID:11756451 MGI:2176350 NCBI chr14:44,265,017...44,308,897 JBrowse link
G SGPP2 sphingosine-1-phosphate phosphatase 2 involved_in ISO (PMID:12411432) UniProt PMID:12411432 NCBI chr2B:109,668,923...109,803,950
Ensembl chr2B:228,300,673...228,381,565
JBrowse link
G SPHK1 sphingosine kinase 1 involved_in ISO (PMID:20577214) UniProt PMID:20577214 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in
acts_upstream_of_or_within
ISO (MGI:3703830|PMID:17346996)
(MGI:3608224|PMID:16093248)
UniProt
MGI
PMID:16093248 PMID:17346996 MGI:3608224 MGI:3703830 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767
JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in ISO (PMID:23707606)
(MGI:5645206|PMID:19666465)
BHF-UCL PMID:19666465 PMID:23707606 MGI:5645206 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in ISO (PMID:7678411), (PMID:9445252)
(PMID:17101830), (PMID:19666465)
UniProt
BHF-UCL
PMID:7678411 PMID:9445252 PMID:17101830 PMID:19666465 NCBI chr14:35,428,676...35,489,359
Ensembl chr14:53,706,723...53,767,393
JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase acts_upstream_of_or_within ISO (MGI:1328867|PMID:9894812) MGI PMID:9894812 MGI:1328867 NCBI chr11:107,107,114...107,114,594
Ensembl chr11:110,949,708...110,957,599
JBrowse link
G QDPR quinoid dihydropteridine reductase involved_in ISO PMID:1898002 RGD
UniProt
PMID:660556 PMID:1898002 PMID:9235988 RGD:4139903 RGD:5128582 RGD:8553309 NCBI chr 4:11,906,439...11,932,311
Ensembl chr 4:17,199,772...17,225,667
JBrowse link
G SPR sepiapterin reductase ISO RGD PMID:2179471 RGD:1600056 NCBI chr2A:72,939,621...72,944,669
Ensembl chr2A:74,433,056...74,438,105
JBrowse link
tetrahydrobiopterin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPR sepiapterin reductase acts_upstream_of_or_within ISO (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chr2A:72,939,621...72,944,669
Ensembl chr2A:74,433,056...74,438,105
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12659
    metabolic process 7934
      small molecule metabolic process 1289
        alcohol metabolic process 264
          polyol metabolic process 91
            1,5-anhydro-D-fructose metabolic process + 0
            2-deoxystreptamine metabolic process + 0
            alditol metabolic process + 13
            butirosin metabolic process + 0
            diol metabolic process + 22
            gentamycin metabolic process + 1
            inositol metabolic process + 6
            inositol phosphate metabolic process + 45
            kanamycin metabolic process + 0
            neomycin metabolic process + 0
            paromomycin metabolic process + 0
            phytosphingosine metabolic process + 1
            polyol biosynthetic process + 49
            polyol catabolic process + 15
            streptomycin metabolic process + 0
            tobramycin metabolic process + 0
            triethanolamine metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 12659
    metabolic process 7934
      organic substance metabolic process 7647
        organic hydroxy compound metabolic process 424
          alcohol metabolic process 264
            polyol metabolic process 91
              1,5-anhydro-D-fructose metabolic process + 0
              2-deoxystreptamine metabolic process + 0
              alditol metabolic process + 13
              butirosin metabolic process + 0
              diol metabolic process + 22
              gentamycin metabolic process + 1
              inositol metabolic process + 6
              inositol phosphate metabolic process + 45
              kanamycin metabolic process + 0
              neomycin metabolic process + 0
              paromomycin metabolic process + 0
              phytosphingosine metabolic process + 1
              polyol biosynthetic process + 49
              polyol catabolic process + 15
              streptomycin metabolic process + 0
              tobramycin metabolic process + 0
              triethanolamine metabolic process + 0
paths to the root