ONTOLOGY REPORT - ANNOTATIONS
Term: secondary metabolic process
Accession: GO:0019748
browse the term
Definition: The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
Synonyms: exact_synonym: secondary metabolism; secondary metabolite metabolic process; secondary metabolite metabolism
xref: Wikipedia:Secondary_metabolism
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Acmsd
aminocarboxymuconate semialdehyde decarboxylase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936469:40,858,338...40,904,807
Ensembl chrNW_004936469:40,858,338...40,904,807
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Ovca2
OVCA2 serine hydrolase domain containing
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936538:8,110,075...8,111,436
Ensembl chrNW_004936538:8,110,203...8,111,119
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Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
RGD
PMID:27071940
RGD:12910550
NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
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Ahr
aryl hydrocarbon receptor
ISO
RGD
PMID:28959666
RGD:401794432
NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588
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Cpt1a
carnitine palmitoyltransferase 1A
ISO
RGD
PMID:28959666
RGD:401794432
NCBI chrNW_004936599:1,491,934...1,535,101
Ensembl chrNW_004936599:1,482,172...1,535,119
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Lcat
lecithin-cholesterol acyltransferase
ISO
RGD
PMID:28959666
RGD:401794432
NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248
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Lipc
lipase C, hepatic type
ISO
RGD
PMID:28959666
RGD:401794432
NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686
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LOC101970215
cytochrome P450 2W1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936754:1,203,004...1,208,131
Ensembl chrNW_004936754:1,203,017...1,208,131
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Scarb1
scavenger receptor class B member 1
ISO
RGD
PMID:28959666
RGD:401794432
NCBI chrNW_004936558:530,828...555,098
Ensembl chrNW_004936558:530,828...552,892
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Abcc2
ATP binding cassette subfamily C member 2
ISO
RGD
PMID:19255943
RGD:11081014
NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393
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Pon3
paraoxonase 3
ISO
RGD
PMID:12946270
RGD:1303961
NCBI chrNW_004936585:4,902,430...4,928,377
Ensembl chrNW_004936585:4,902,289...4,929,556
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LOC101957277
cytochrome P450 2A13
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936661:3,280,454...3,287,255
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LOC101961588
cytochrome P450 2D17
involved_in
ISO
(PMID:19438707)
BHF-UCL
PMID:19438707
NCBI chrNW_004936718:153,340...157,966
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LOC101966838
cytochrome P450 2A13-like
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936661:3,148,345...3,154,887
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LOC101969148
cytochrome P450 1A1
ISO
Coumarin derivative metabolism
RGD
PMID:11780761
RGD:2306676
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
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Akr1a1
aldo-keto reductase family 1 member A1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214
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Akr1b1
aldo-keto reductase family 1 member B
involved_in
ISO
(PMID:20837989)
UniProt
PMID:20837989
NCBI chrNW_004936579:1,312,175...1,328,397
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Cbr4
carbonyl reductase 4
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936516:1,184,859...1,205,668
Ensembl chrNW_004936516:1,181,524...1,205,760
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LOC101954786
aldo-keto reductase family 1 member C1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936484:9,312,113...9,329,269
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LOC101974041
aflatoxin B1 aldehyde reductase member 2
involved_in
ISO
(PMID:20837989)
UniProt
PMID:20837989
NCBI chrNW_004936474:5,565,715...5,573,048
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Akr1a1
aldo-keto reductase family 1 member A1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214
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Akr1b1
aldo-keto reductase family 1 member B
involved_in
ISO
(PMID:20837989)
UniProt
PMID:20837989
NCBI chrNW_004936579:1,312,175...1,328,397
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Cbr4
carbonyl reductase 4
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936516:1,184,859...1,205,668
Ensembl chrNW_004936516:1,181,524...1,205,760
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LOC101954786
aldo-keto reductase family 1 member C1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936484:9,312,113...9,329,269
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LOC101974041
aflatoxin B1 aldehyde reductase member 2
involved_in
ISO
(PMID:20837989)
UniProt
PMID:20837989
NCBI chrNW_004936474:5,565,715...5,573,048
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Hsd17b3
hydroxysteroid 17-beta dehydrogenase 3
ISO
methoxychlor
RGD
PMID:18401575
RGD:4890969
NCBI chrNW_004936487:228,301...282,495
Ensembl chrNW_004936487:228,557...245,295
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LOC101969148
cytochrome P450 1A1
ISO
Deltamethrin (pyrethroid)
RGD
PMID:16169030
RGD:2306660
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
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Star
steroidogenic acute regulatory protein
ISO
methoxychlor
RGD
PMID:18401575
RGD:4890969
NCBI chrNW_004936710:1,523,289...1,530,181
Ensembl chrNW_004936710:1,523,355...1,529,672
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Asip
agouti signaling protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7665913)
Ensembl MGI
PMID:7665913
GO_REF:0000107
NCBI chrNW_004936561:6,341,667...6,346,440
Ensembl chrNW_004936561:6,341,623...6,346,458
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Cited1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936762:1,387,354...1,392,955
Ensembl chrNW_004936762:1,387,346...1,391,967
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Dct
dopachrome tautomerase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7665913)
UniProt MGI Ensembl
PMID:7665913
GO_REF:0000043 GO_REF:0000107
NCBI chrNW_004936472:15,074,947...15,110,427
Ensembl chrNW_004936472:15,074,633...15,110,534
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LOC101963449
D-dopachrome decarboxylase
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004936619:1,043,006...1,045,054
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Mc1r
melanocortin 1 receptor
acts_upstream_of_or_within
ISO
(PMID:7665913)
MGI
PMID:7665913
NCBI chrNW_004936641:193,885...198,730
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Myo5a
myosin VA
acts_upstream_of_or_within
ISO
(PMID:7665913)
MGI
PMID:7665913
NCBI chrNW_004936471:14,105,832...14,257,386
Ensembl chrNW_004936471:14,111,841...14,254,246
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Oca2
OCA2 melanosomal transmembrane protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7665913), (PMID:9548375)
Ensembl MGI TreeGrafter
PMID:7665913 PMID:9548375
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936471:38,612,450...38,952,150
Ensembl chrNW_004936471:38,612,427...38,952,199
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Pmel
premelanosome protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7665913)
Ensembl MGI
PMID:7665913
GO_REF:0000107
NCBI chrNW_004936646:368,064...379,085
Ensembl chrNW_004936646:365,809...379,130
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Slc24a5
solute carrier family 24 member 5
involved_in acts_upstream_of
IEA ISO
(PMID:18166528)
Ensembl MGI
PMID:18166528
GO_REF:0000107
NCBI chrNW_004936471:10,470,078...10,492,334
Ensembl chrNW_004936471:10,470,046...10,493,104
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Trpc1
transient receptor potential cation channel subfamily C member 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936540:4,340,672...4,417,655
Ensembl chrNW_004936540:4,323,528...4,418,685
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Tyr
tyrosinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9548375) (PMID:7665913)
UniProt MGI TreeGrafter Ensembl
PMID:7665913 PMID:9548375
GO_REF:0000043 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936736:421,623...519,085
Ensembl chrNW_004936736:421,598...519,253
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Tyrp1
tyrosinase related protein 1
involved_in
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004936539:6,537,448...6,555,440
Ensembl chrNW_004936539:6,537,509...6,556,513
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Dct
dopachrome tautomerase
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936472:15,074,947...15,110,427
Ensembl chrNW_004936472:15,074,633...15,110,534
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Oca2
OCA2 melanosomal transmembrane protein
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936471:38,612,450...38,952,150
Ensembl chrNW_004936471:38,612,427...38,952,199
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Slc45a2
solute carrier family 45 member 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936518:7,094,949...7,139,961
Ensembl chrNW_004936518:7,095,038...7,137,277
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Bcl2
BCL2 apoptosis regulator
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:11709185)
Ensembl MGI
PMID:11709185
GO_REF:0000107
NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
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Myo5a
myosin VA
acts_upstream_of_or_within
ISO
(PMID:9548375)
MGI
PMID:9548375
NCBI chrNW_004936471:14,105,832...14,257,386
Ensembl chrNW_004936471:14,111,841...14,254,246
G
Tyrp1
tyrosinase related protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9548375)
Ensembl MGI
PMID:9548375
GO_REF:0000107
NCBI chrNW_004936539:6,537,448...6,555,440
Ensembl chrNW_004936539:6,537,509...6,556,513
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Vhl
von Hippel-Lindau tumor suppressor
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22627278)
Ensembl MGI
PMID:22627278
GO_REF:0000107
NCBI chrNW_004936602:3,135,790...3,140,622
G
Mfsd12
major facilitator superfamily domain containing 12
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936588:2,011,838...2,019,119
Ensembl chrNW_004936588:2,011,506...2,019,125
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Opn3
opsin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936526:8,833,495...8,876,631
Ensembl chrNW_004936526:8,833,455...8,876,729
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Rapgef2
Rap guanine nucleotide exchange factor 2
involved_in
ISO
(MGI:5499726|PMID:16272156)
UniProt
PMID:16272156
MGI:5499726
NCBI chrNW_004936576:5,583,847...5,746,583
Ensembl chrNW_004936576:5,583,805...5,746,671
G
Slc24a5
solute carrier family 24 member 5
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18166528)
Ensembl MGI
PMID:18166528
GO_REF:0000107
NCBI chrNW_004936471:10,470,078...10,492,334
Ensembl chrNW_004936471:10,470,046...10,493,104
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Wnt5a
Wnt family member 5A
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936473:6,031,627...6,052,211
Ensembl chrNW_004936473:6,029,976...6,052,159
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Ddc
dopa decarboxylase
ISO
scoparone
RGD
PMID:19185027
RGD:5128879
NCBI chrNW_004936686:1,322,153...1,405,434
Ensembl chrNW_004936686:1,301,207...1,405,384
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Th
tyrosine hydroxylase
ISO
scoparone
RGD
PMID:19185027
RGD:5128879
NCBI chrNW_004936794:478,651...486,887
Ensembl chrNW_004936794:478,614...487,061
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Appl1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936473:7,580,495...7,647,471
Ensembl chrNW_004936473:7,579,780...7,611,923
G
Asip
agouti signaling protein
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936561:6,341,667...6,346,440
Ensembl chrNW_004936561:6,341,623...6,346,458
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Atp7a
ATPase copper transporting alpha
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
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Cdh3
cadherin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936475:18,908,031...18,954,402
Ensembl chrNW_004936475:18,906,493...18,955,072
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Gipc1
GIPC PDZ domain containing family member 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936659:3,019,829...3,030,280
Ensembl chrNW_004936659:3,012,012...3,026,883
G
Opn3
opsin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936526:8,833,495...8,876,631
Ensembl chrNW_004936526:8,833,455...8,876,729
G
Pmel
premelanosome protein
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936646:368,064...379,085
Ensembl chrNW_004936646:365,809...379,130
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Rab38
RAB38, member RAS oncogene family
ISO
RGD
PMID:17043139
RGD:152025192
NCBI chrNW_004936736:1,304,290...1,360,412
Ensembl chrNW_004936736:1,304,185...1,361,221
G
Tyrp1
tyrosinase related protein 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936539:6,537,448...6,555,440
Ensembl chrNW_004936539:6,537,509...6,556,513
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Ctns
cystinosin, lysosomal cystine transporter
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936677:342,964...360,890
Ensembl chrNW_004936677:343,042...360,879
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Mfsd12
major facilitator superfamily domain containing 12
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936588:2,011,838...2,019,119
Ensembl chrNW_004936588:2,011,506...2,019,125
G
Slc7a11
solute carrier family 7 member 11
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:16037214)
Ensembl MGI
PMID:16037214
GO_REF:0000107
NCBI chrNW_004936535:9,177,305...9,242,743
Ensembl chrNW_004936535:9,177,143...9,242,566
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Lactb2
lactamase beta 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936496:15,292,216...15,319,800
Ensembl chrNW_004936496:15,292,216...15,319,786
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Bdh2
3-hydroxybutyrate dehydrogenase 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936520:278,467...304,525
Ensembl chrNW_004936520:278,435...304,770
G
LOC101969421
cytochrome P450 1A2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484
G
Arl1
ADP ribosylation factor like GTPase 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936492:12,583,878...12,595,824
Ensembl chrNW_004936492:12,583,887...12,595,798
G
As3mt
arsenite methyltransferase
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936600:3,050,946...3,069,786
Ensembl chrNW_004936600:3,051,129...3,069,690
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936481:15,885,375...15,910,216
Ensembl chrNW_004936481:15,885,280...15,910,267
G
LOC101969148
cytochrome P450 1A1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17166882)
Ensembl MGI
PMID:17166882
GO_REF:0000107
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
G
LOC101969421
cytochrome P450 1A2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17166882)
Ensembl MGI
PMID:17166882
GO_REF:0000107
NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484
G
LOC101969732
dimethylaniline monooxygenase [N-oxide-forming] 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936481:15,857,556...15,873,883
Ensembl chrNW_004936481:15,857,559...15,880,184
G
LOC101970101
cytochrome P450 1B1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:10051580), (PMID:17166882)
Ensembl MGI
PMID:10051580 PMID:17166882
GO_REF:0000107
NCBI chrNW_004936663:345,021...355,188
Ensembl chrNW_004936663:348,368...355,191
G
N6amt1
N-6 adenine-specific DNA methyltransferase 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936500:13,086,873...13,099,814
Ensembl chrNW_004936500:13,084,595...13,099,844
G
Pam
peptidylglycine alpha-amidating monooxygenase
ISO
enhances lethality of scorpion neurotoxin BmK ITa1
RGD
PMID:12721493
RGD:6483565
NCBI chrNW_004936523:1,492,795...1,786,942
Ensembl chrNW_004936523:1,493,450...1,750,524
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all