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ONTOLOGY REPORT - ANNOTATIONS

Term:choline metabolic process
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Accession:GO:0019695 term browser browse the term
Definition:The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
Synonyms:exact_synonym: choline metabolism

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choline metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP
IDA		 RGD PMID:16628397 PMID:1133098 PMID:8737018 RGD:1580871, RGD:2301187, RGD:2301207 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase IDA RGD PMID:1133098 PMID:126256 RGD:2301187, RGD:2301195 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Chka choline kinase alpha IDA RGD PMID:12815193 RGD:1626304 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase TAS RGD PMID:1710985 RGD:632576 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 involved_in
acts_upstream_of_or_within		 IBA
ISO
ISS		 PMID:21873635
(MGI:6217381|PMID:26888014)
(MGI:3587554|PMID:15788404)
GO_REF:0000024
(PMID:15788404)		 RGD
UniProt		 PMID:15788404 PMID:26888014 PMID:21873635 GO_REF:0000024 MGI:3587554 MGI:6217381, RGD:13792537 NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077 		JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase involved_in TAS
ISO
IEA		 (PMID:10102904)
GO_REF:0000107		 RGD
Ensembl		 PMID:10102904 PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G Sardh sarcosine dehydrogenase involved_in TAS
NAS		 PMID:9839943 RGD
UniProt		 PMID:9839943 PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
glycine betaine biosynthetic process from choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G Chdh choline dehydrogenase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        choline metabolic process 8
          choline biosynthetic process + 0
          choline catabolic process 2
          glycine betaine biosynthetic process from choline 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      nitrogen compound metabolic process 9982
        ammonium ion metabolic process 26
          choline metabolic process 8
            choline biosynthetic process + 0
            choline catabolic process 2
            glycine betaine biosynthetic process from choline 2
paths to the root