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ONTOLOGY REPORT - ANNOTATIONS


Term:choline metabolic process
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Accession:GO:0019695 term browser browse the term
Definition:The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
Synonyms:exact_synonym: choline metabolism


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choline metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP
IDA
RGD PMID:16628397, PMID:1133098, PMID:8737018 RGD:1580871, RGD:2301187, RGD:2301207 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bche butyrylcholinesterase IDA RGD PMID:1133098, PMID:126256 RGD:2301187, RGD:2301195 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Chka choline kinase alpha IDA RGD PMID:12815193 RGD:1626304 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Dmgdh dimethylglycine dehydrogenase TAS RGD PMID:1710985 RGD:632576 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 ISO
ISS
IBA
(PMID:15788404)
(MGI:MGI:3587554|PMID:15788404), (MGI:MGI:6217381|PMID:26888014)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:15788404, PMID:26888014, PMID:21873635 GO_REF:0000024, MGI:MGI:3587554, MGI:MGI:6217381, RGD:13792537 NCBI chr16:48,315,500...48,437,258
Ensembl chr16:48,315,914...48,437,242
JBrowse link
choline catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase TAS
ISO
IEA
(PMID:10102904)
GO_REF:0000107
RGD
Ensembl
PMID:10102904, PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Sardh sarcosine dehydrogenase TAS
NAS
PMID:9839943 RGD
UniProt
PMID:9839943, PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
glycine betaine biosynthetic process from choline term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:51,619,007...51,651,267
Ensembl chr18:51,619,007...51,651,267
JBrowse link
G Chdh choline dehydrogenase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:6,078,083...6,109,386
Ensembl chr16:6,078,122...6,109,382
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      organic substance metabolic process 11636
        choline metabolic process 8
          choline biosynthetic process + 0
          choline catabolic process 2
          glycine betaine biosynthetic process from choline 2
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      nitrogen compound metabolic process 10342
        ammonium ion metabolic process 26
          choline metabolic process 8
            choline biosynthetic process + 0
            choline catabolic process 2
            glycine betaine biosynthetic process from choline 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.