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Term:tryptophan catabolic process to kynurenine
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Accession:GO:0019441 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
Synonyms:exact_synonym: tryptophan breakdown to kynurenine;   tryptophan degradation to kynurenine
 xref: MetaCyc:TRPKYNCAT-PWY

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tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase ISO (MGI:3587527|PMID:15866519) MGI PMID:15866519 MGI:3587527 NCBI chr17:72,265,365...72,285,764
Ensembl chr17:77,816,908...77,835,905
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO (MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753) RGD
PMID:2419335, PMID:10719243, PMID:11513477, PMID:11751753 MGI:2151782, MGI:2156954, RGD:2290190, RGD:2290543 NCBI chr 8:39,108,310...39,123,611
Ensembl chr 8:36,617,312...36,632,352
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 ISO (PMID:17671174)
PMID:17499941, PMID:17671174 MGI:3712725, MGI:3719924 NCBI chr 8:39,149,045...39,209,671
Ensembl chr 8:36,665,240...36,717,420
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase ISO (PMID:27762317) UniProtKB PMID:27762317 NCBI chr 4:148,269,097...148,285,533
Ensembl chr 4:160,085,645...160,102,266
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    metabolic process 7977
      cellular metabolic process 7331
        cellular ketone metabolic process 185
          kynurenine metabolic process 8
            tryptophan catabolic process to kynurenine 4
Path 2
Term Annotations click to browse term
  biological_process 12566
    metabolic process 7977
      organic substance metabolic process 7668
        organonitrogen compound metabolic process 4643
          amine metabolic process 100
            cellular amine metabolic process 97
              cellular biogenic amine metabolic process 84
                indolalkylamine metabolic process 7
                  tryptophan metabolic process 7
                    tryptophan catabolic process 6
                      tryptophan catabolic process to kynurenine 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.