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ONTOLOGY REPORT - ANNOTATIONS


Term:lipoxygenase pathway
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Accession:GO:0019372 term browser browse the term
Definition:The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.


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lipoxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISO
IBA
IDA
(PMID:8319693)
PMID:21873635
PMID:23382512
(MGI:1202206|PMID:9501222), (MGI:66203|PMID:8188678)
RGD PMID:8188678 PMID:8319693 PMID:9501222, PMID:21873635, PMID:23382512 MGI:1202206 MGI:66203, RGD:13792537, RGD:8554649 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:15629692), (PMID:21558561)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15629692 PMID:21558561, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal involved_in IDA
IBA
PMID:23382512
PMID:21873635
UniProt
GO_Central
PMID:23382512, PMID:21873635 RGD:8554649, RGD:13792537 NCBI chr10:56,927,676...56,935,141
Ensembl chr10:56,927,676...56,935,141
JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in IDA
ISO
IBA
(MGI:1101294|PMID:8798642), (MGI:66203|PMID:8188678)
PMID:21873635
(PMID:1944593), (PMID:23242647)
RGD PMID:1944593 PMID:8188678 PMID:8798642 PMID:23242647, PMID:8117750, PMID:21873635 MGI:1101294 MGI:66203, RGD:70288, RGD:13792537 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IBA
ISO
IEA
IDA
PMID:21873635
(MGI:1097306|PMID:9305900)
GO_REF:0000107
PMID:23382512
RGD
Ensembl
PMID:9305900, PMID:21873635, PMID:23382512 GO_REF:0000107 MGI:1097306, RGD:13792537, RGD:8554649 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein IMP
IDA
RGD PMID:18945963, PMID:17517102 RGD:2313900, RGD:2313910 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:20921226)
GO_REF:0000024
RGD
UniProt
PMID:20921226, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA
ISS
(PMID:11115402)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11115402 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO
ISS
(PMID:11115402)
GO_REF:0000024
RGD
UniProt
PMID:11115402 GO_REF:0000024 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (MGI:4459354|PMID:20424323) RGD PMID:20424323 MGI:4459354 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular metabolic process 10755
        cellular lipid metabolic process 1018
          fatty acid metabolic process 427
            lipoxygenase pathway 11
              green leaf volatile biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular metabolic process 10755
        organic acid metabolic process 1010
          oxoacid metabolic process 978
            carboxylic acid metabolic process 959
              monocarboxylic acid metabolic process 659
                fatty acid metabolic process 427
                  lipoxygenase pathway 11
                    green leaf volatile biosynthetic process 0
paths to the root