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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclooxygenase pathway
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Accession:GO:0019371 term browser browse the term
Definition:The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.


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cyclooxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB1 bradykinin receptor B1 involved_in IMP (PMID:23846981) AgBase PMID:23846981 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:1419907) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:1419907 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (PMID:28973536) MGI PMID:28973536 NCBI chr12:55,406,730...55,424,120
Ensembl chr12:55,405,483...55,424,118 		JBrowse link
G SPHK1 sphingosine kinase 1 ISO RGD PMID:18723875 RGD:2311353 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    metabolic process 10347
      organic substance metabolic process 9911
        olefinic compound metabolic process 148
          arachidonic acid metabolic process 48
            cyclooxygenase pathway 5
Path 2
Term Annotations click to browse term
  biological_process 17813
    metabolic process 10347
      cellular metabolic process 9044
        organic acid metabolic process 928
          oxoacid metabolic process 910
            carboxylic acid metabolic process 891
              monocarboxylic acid metabolic process 631
                fatty acid metabolic process 404
                  unsaturated fatty acid metabolic process 110
                    prostanoid metabolic process 54
                      prostaglandin metabolic process 53
                        prostaglandin biosynthetic process 35
                          cyclooxygenase pathway 5
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