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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine nucleotide biosynthetic process
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Accession:GO:0019363 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
Synonyms:exact_synonym: pyridine nucleotide anabolism;   pyridine nucleotide biosynthesis;   pyridine nucleotide formation;   pyridine nucleotide synthesis
 xref: MetaCyc:PYRIDNUCSYN-PWY


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'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
ISS
IEA
(PMID:31883644)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:100,471,066...100,473,327
Ensembl chr 1:100,470,722...100,473,459
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kynu kynureninase involved_in ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000041
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 GO_REF:0000041 MGI:3522067 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA
GO_REF:0000041 UniProt PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000041
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)
(MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699 PMID:16914673 PMID:27735788, PMID:21873635 GO_REF:0000041 MGI:3522067 MGI:3654729 MGI:6206974, RGD:13792537 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:22449973, PMID:21873635 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:70,379,346...70,559,311
Ensembl chr13:70,379,346...70,559,458
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3654729|PMID:16914673)
GO_REF:0000041
RGD
UniProt
PMID:16914673, PMID:21873635 GO_REF:0000041 MGI:3654729, RGD:13792537 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3522057|PMID:15271799), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:54902|PMID:7439685), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 PMID:9330624 PMID:9539108 PMID:9627357 PMID:10627286 PMID:14757696 PMID:15271799 PMID:15998684 MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Nadk NAD kinase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069, PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:58,462,588...58,504,735
Ensembl chr 2:58,462,588...58,504,728
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      cellular metabolic process 10838
        heterocycle metabolic process 5546
          heterocycle biosynthetic process 3901
            pyridine-containing compound biosynthetic process 24
              pyridine nucleotide biosynthetic process 19
                nicotinamide nucleotide biosynthetic process + 19
                nicotinate nucleotide biosynthetic process + 0
                pyridine nucleotide salvage + 1
Path 2
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      cellular metabolic process 10838
        cellular aromatic compound metabolic process 5627
          nucleobase-containing compound metabolic process 5410
            nucleobase-containing small molecule metabolic process 574
              nucleoside phosphate metabolic process 503
                nucleotide metabolic process 495
                  nucleotide biosynthetic process 239
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process + 19
                      nicotinate nucleotide biosynthetic process + 0
                      pyridine nucleotide salvage + 1
paths to the root