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ONTOLOGY REPORT - ANNOTATIONS

Term:pyridine nucleotide biosynthetic process
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Accession:GO:0019363 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
Synonyms:exact_synonym: pyridine nucleotide anabolism;   pyridine nucleotide biosynthesis;   pyridine nucleotide formation;   pyridine nucleotide synthesis


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pyridine nucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
ISS
IEA		 (PMID:31883644)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:208,410,914...208,439,242
Ensembl chr 1:198,981,604...199,009,869 		JBrowse link
'de novo' NAD biosynthetic process from L-tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,544,822...103,560,408
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:74,161,761...74,200,651
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:104,094,983...104,097,244
Ensembl chr 1:94,958,316...94,960,722 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Kynu kynureninase involved_in ISS
ISO		 GO_REF:0000024
(PMID:28792876)		 UniProt
RGD		 PMID:28792876 GO_REF:0000024 NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr 1:208,410,914...208,439,242
Ensembl chr 1:198,981,604...199,009,869 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000041
(PMID:15381699)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15381699 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:109,457,328...109,460,817
Ensembl chr 7:107,576,627...107,580,102 		JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000041
GO_REF:0000033
(PMID:27735788)
(PMID:15381699), (PMID:16914673)		 UniProt
GO_Central
RGD		 PMID:15381699 PMID:16914673 PMID:27735788 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:165,193,301...165,211,213
Ensembl chr 5:159,910,242...159,928,180 		JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IBA
IEA		 GO_REF:0000033
GO_REF:0000041		 GO_Central
UniProt
RGD		 PMID:22449973 GO_REF:0000033 GO_REF:0000041, RGD:13782043 NCBI chr13:67,655,794...67,831,609
Ensembl chr13:65,105,950...65,278,484 		JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000041
GO_REF:0000033
(PMID:16914673)		 UniProt
GO_Central
RGD		 PMID:16914673 GO_REF:0000033 GO_REF:0000041 NCBI chr 8:107,771,124...107,888,528
Ensembl chr 8:98,873,398...99,020,645 		JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:225,475,975...225,503,414
Ensembl chr 1:216,049,437...216,076,791 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000041		 GO_Central
UniProt
RGD		 PMID:8694849 GO_REF:0000033 GO_REF:0000041, RGD:2289495 NCBI chr 1:191,148,715...191,164,006
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
NAD biosynthetic process via the salvage pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA
ISO		 GO_REF:0000033
(PMID:17604275)		 GO_Central
RGD		 PMID:17604275 GO_REF:0000033 NCBI chr 7:109,457,328...109,460,817
Ensembl chr 7:107,576,627...107,580,102 		JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (PMID:10627286), (PMID:14757696), (PMID:15271799), (PMID:15998684), (PMID:1953691), (PMID:3377761), (PMID:7439685), (PMID:9067418), (PMID:9169132), (PMID:9330624), (PMID:9539108), (PMID:9627357) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Nadk NAD kinase involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:22550069 GO_REF:0000033, RGD:13703105 NCBI chr 5:171,427,973...171,458,586
Ensembl chr 5:166,145,481...166,176,322 		JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 2:59,844,854...59,886,989
Ensembl chr 2:58,117,674...58,159,808 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        biosynthetic process 8663
          pyridine-containing compound biosynthetic process 24
            pyridine nucleotide biosynthetic process 19
              nicotinamide nucleotide biosynthetic process + 19
              nicotinate nucleotide biosynthetic process + 0
              pyridine nucleotide salvage + 1
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        primary metabolic process 10746
          nucleobase-containing compound metabolic process 5951
            nucleobase-containing small molecule metabolic process 731
              nucleoside phosphate metabolic process 696
                nucleotide metabolic process 542
                  pyridine nucleotide metabolic process 236
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process + 19
                      nicotinate nucleotide biosynthetic process + 0
                      pyridine nucleotide salvage + 1
paths to the root