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ONTOLOGY REPORT - ANNOTATIONS


Term:nicotinamide nucleotide biosynthetic process
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Accession:GO:0019359 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
Synonyms:exact_synonym: nicotinamide nucleotide anabolism;   nicotinamide nucleotide biosynthesis;   nicotinamide nucleotide formation;   nicotinamide nucleotide synthesis



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'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nadsyn1 NAD synthetase 1 involved_in ISO
ISS
IEA
(PMID:31883644)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:31883644 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Kynu kynureninase involved_in ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Nadsyn1 NAD synthetase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 PMID:21873635 GO_REF:0000041 MGI:3522067, RGD:13792537 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Naprt nicotinate phosphoribosyltransferase involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:8694849 GO_REF:0000041, RGD:2289495 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000041
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)
(MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699 PMID:16914673 PMID:27735788 PMID:21873635 GO_REF:0000041 MGI:3522067 MGI:3654729 MGI:6206974, RGD:13792537 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 involved_in IMP
IEA
IBA
GO_REF:0000002
GO_REF:0000041
PMID:21873635
InterPro
UniProt
RGD
PMID:22449973 PMID:21873635 GO_REF:0000002 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3654729|PMID:16914673)
GO_REF:0000041
RGD
UniProt
PMID:16914673 PMID:21873635 GO_REF:0000041 MGI:3654729, RGD:13792537 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Qprt quinolinate phosphoribosyltransferase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:8694849 PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3522057|PMID:15271799), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:54902|PMID:7439685), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Nadk NAD kinase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069 PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:58,117,674...58,159,815
Ensembl chr 2:58,117,674...58,159,808
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19812
    metabolic process 12023
      biosynthetic process 6215
        cellular biosynthetic process 6056
          cellular nitrogen compound biosynthetic process 5025
            pyridine-containing compound biosynthetic process 24
              pyridine nucleotide biosynthetic process 19
                nicotinamide nucleotide biosynthetic process 19
                  NAD biosynthetic process + 15
                  NADP biosynthetic process 4
                  nicotinamide nucleotide biosynthetic process from aspartate + 0
                  nicotinamide nucleotide biosynthetic process from niacinamide 0
Path 2
Term Annotations click to browse term
  biological_process 19812
    metabolic process 12023
      cellular metabolic process 10904
        cellular aromatic compound metabolic process 5730
          nucleobase-containing compound metabolic process 5504
            nucleobase-containing small molecule metabolic process 585
              nucleoside phosphate metabolic process 518
                nucleotide metabolic process 510
                  nucleotide biosynthetic process 245
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process + 15
                        NADP biosynthetic process 4
                        nicotinamide nucleotide biosynthetic process from aspartate + 0
                        nicotinamide nucleotide biosynthetic process from niacinamide 0
paths to the root