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ONTOLOGY REPORT - ANNOTATIONS


Term:isopentenyl diphosphate biosynthetic process, mevalonate pathway
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Accession:GO:0019287 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Synonyms:exact_synonym: Ac-MVA pathway;   acetate-mevalonate pathway;   isopentenyl diphosphate anabolism, mevalonate pathway;   isopentenyl diphosphate biosynthetic process via mevalonate;   isopentenyl diphosphate formation, mevalonate pathway;   isopentenyl diphosphate synthesis, mevalonate pathway



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isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MVD mevalonate diphosphate decarboxylase involved_in IBA
IEA
ISO
(PMID:21873635) GO_Central
GO_Central
InterPro
UniProt
RGD
InterPro
PMID:197206 PMID:21873635 GO_REF:0000002 GO_REF:0000104 RGD:2316852 NCBI chr 6:1,008,100...1,014,303
Ensembl chr 6:1,008,100...1,014,303
JBrowse link
G MVK mevalonate kinase involved_in IEA
IBA
ISO
(PMID:21873635) UniProt
UniProt
GO_Central
RGD
GO_Central
PMID:197206 PMID:21873635 GO_REF:0000041 RGD:2316852 NCBI chr14:41,320,790...41,357,437
Ensembl chr14:41,281,673...41,357,368
JBrowse link
G PMVK phosphomevalonate kinase involved_in IBA
IEA
ISO
(PMID:21873635) GO_Central
UniProt
RGD
UniProt
GO_Central
PMID:197206 PMID:21873635 GO_REF:0000041 GO_REF:0000104 RGD:2316852 NCBI chr 4:94,861,500...94,913,743
Ensembl chr 4:94,861,712...94,874,771
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17484
    metabolic process 11006
      organic substance metabolic process 10576
        thioester metabolic process 91
          acyl-CoA metabolic process 91
            acetyl-CoA metabolic process 40
              isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 17484
    cellular process 16258
      cellular metabolic process 8602
        heterocycle metabolic process 5407
          nucleobase-containing compound metabolic process 5259
            nucleobase-containing small molecule metabolic process 525
              nucleoside phosphate metabolic process 459
                nucleotide metabolic process 452
                  ribonucleotide metabolic process 328
                    purine ribonucleotide metabolic process 306
                      acyl-CoA metabolic process 91
                        acetyl-CoA metabolic process 40
                          isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                            isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                            negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
paths to the root