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ONTOLOGY REPORT - ANNOTATIONS


Term:isopentenyl diphosphate biosynthetic process, mevalonate pathway
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Accession:GO:0019287 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Synonyms:exact_synonym: Ac-MVA pathway;   acetate-mevalonate pathway;   isopentenyl diphosphate anabolism, mevalonate pathway;   isopentenyl diphosphate biosynthetic process via mevalonate;   isopentenyl diphosphate formation, mevalonate pathway;   isopentenyl diphosphate synthesis, mevalonate pathway



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isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MVD mevalonate diphosphate decarboxylase involved_in IBA
ISO
IEA
(PMID:21873635) GO_Central
RGD
InterPro
InterPro
UniProt
PMID:197206 PMID:21873635 GO_REF:0000002 GO_REF:0000104 RGD:2316852 NCBI chr 5:64,683,146...64,691,576
Ensembl chr 5:64,682,276...64,691,073
JBrowse link
G MVK mevalonate kinase involved_in ISO
IEA
IBA
(PMID:21873635) RGD
UniProt
GO_Central
UniProt
PMID:197206 PMID:21873635 GO_REF:0000041 RGD:2316852 NCBI chr26:17,497,516...17,519,015
Ensembl chr26:17,497,513...17,519,385
JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA
IBA
ISO
(PMID:21873635) UniProt
GO_Central
RGD
UniProt
PMID:197206 PMID:21873635 GO_REF:0000041 GO_REF:0000104 RGD:2316852 NCBI chr 7:42,532,968...42,563,618
Ensembl chr 7:42,533,217...42,540,625
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17438
    metabolic process 11382
      organic substance metabolic process 10955
        thioester metabolic process 89
          acyl-CoA metabolic process 89
            acetyl-CoA metabolic process 38
              isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 17438
    cellular process 16174
      cellular metabolic process 8902
        heterocycle metabolic process 5529
          nucleobase-containing compound metabolic process 5380
            nucleobase-containing small molecule metabolic process 564
              nucleoside phosphate metabolic process 495
                nucleotide metabolic process 488
                  ribonucleotide metabolic process 359
                    purine ribonucleotide metabolic process 336
                      acyl-CoA metabolic process 89
                        acetyl-CoA metabolic process 38
                          isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                            isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                            negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
paths to the root