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ONTOLOGY REPORT - ANNOTATIONS


Term:isopentenyl diphosphate biosynthetic process, mevalonate pathway
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Accession:GO:0019287 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Synonyms:exact_synonym: Ac-MVA pathway;   acetate-mevalonate pathway;   isopentenyl diphosphate anabolism, mevalonate pathway;   isopentenyl diphosphate biosynthetic process via mevalonate;   isopentenyl diphosphate formation, mevalonate pathway;   isopentenyl diphosphate synthesis, mevalonate pathway



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isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvd mevalonate diphosphate decarboxylase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
RGD
PMID:197206 PMID:21873635 GO_REF:0000002 GO_REF:0000104, RGD:2316852, RGD:13792537 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mvk mevalonate kinase involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:197206 PMID:21873635 GO_REF:0000041, RGD:2316852, RGD:13792537 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pmvk phosphomevalonate kinase involved_in IDA
IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt
RGD
PMID:197206 PMID:21873635 GO_REF:0000041, RGD:2316852, RGD:13792537 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    metabolic process 12212
      organic substance metabolic process 11753
        thioester metabolic process 94
          acyl-CoA metabolic process 94
            acetyl-CoA metabolic process 40
              isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 19903
    cellular process 18297
      cellular metabolic process 9633
        heterocycle metabolic process 5928
          nucleobase-containing compound metabolic process 5769
            nucleobase-containing small molecule metabolic process 698
              nucleoside phosphate metabolic process 624
                nucleotide metabolic process 614
                  ribonucleotide metabolic process 492
                    purine ribonucleotide metabolic process 471
                      acyl-CoA metabolic process 94
                        acetyl-CoA metabolic process 40
                          isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                            isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                            negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
paths to the root