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ONTOLOGY REPORT - ANNOTATIONS
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Term:
citrulline biosynthetic process
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Accession:
GO:0019240
browse the term
Definition:
The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
Synonyms:
exact_synonym:
citrulline anabolism; citrulline biosynthesis; citrulline formation; citrulline synthesis
xref:
MetaCyc:CITRULBIO-PWY
show annotations for term's descendants Sort by:
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object name
position
reference
evidence
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Rat (4)
Mouse (4)
Human (5)
Chinchilla (4)
Bonobo (4)
Dog (4)
Squirrel (4)
Pig (4)
Green Monkey (5)
Naked Mole-rat (4)
All
Genes (4)
citrulline biosynthetic process
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
involved_in
ISO
(PMID:11092761), (PMID:26297558)
RGD
PMID:11092761
PMID:26297558
NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
G
Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
involved_in
IDA
IBA
GO_REF:0000033
GO_Central
RGD
PMID:7053379
GO_REF:0000033,
RGD:10755426
NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
G
Otc
ornithine transcarbamylase
involved_in
IDA
ISO
IBA
(PMID:2556444), (PMID:8112735)
GO_REF:0000033
RGD
GO_Central
PMID:2556444
PMID:8112735
PMID:9472964
GO_REF:0000033,
RGD:4144071
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
negative regulation of citrulline biosynthetic process
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Atp2b4
ATPase plasma membrane Ca2+ transporting 4
involved_in
ISO
(PMID:19278978)
RGD
PMID:19278978
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20134
cellular process
19326
metabolic process
12309
biosynthetic process
8436
amino acid biosynthetic process
79
alpha-amino acid biosynthetic process
70
citrulline biosynthetic process
4
negative regulation of citrulline biosynthetic process
1
positive regulation of citrulline biosynthetic process
0
regulation of citrulline biosynthetic process
+
1
Path 2
Term
Annotations
biological_process
20134
cellular process
19326
metabolic process
12309
small molecule metabolic process
1899
organic acid metabolic process
1034
oxoacid metabolic process
1023
carboxylic acid metabolic process
1008
carboxylic acid biosynthetic process
326
alpha-amino acid biosynthetic process
70
citrulline biosynthetic process
4
negative regulation of citrulline biosynthetic process
1
positive regulation of citrulline biosynthetic process
0
regulation of citrulline biosynthetic process
+
1