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ONTOLOGY REPORT - ANNOTATIONS


Term:citrulline biosynthetic process
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Accession:GO:0019240 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
Synonyms:exact_synonym: citrulline anabolism;   citrulline biosynthesis;   citrulline formation;   citrulline synthesis
 xref: MetaCyc:CITRULBIO-PWY


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citrulline biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761, PMID:26297558 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7053379, PMID:21873635 RGD:10755426, RGD:13792537 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Otc ornithine carbamoyltransferase IDA
IBA
ISO
PMID:21873635
(PMID:2556444), (PMID:8112735)
RGD PMID:2556444, PMID:8112735, PMID:9472964, PMID:21873635 RGD:4144071, RGD:13792537 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      primary metabolic process 10941
        cellular amino acid metabolic process 276
          cellular amino acid biosynthetic process 71
            alpha-amino acid biosynthetic process 66
              citrulline biosynthetic process 4
                negative regulation of citrulline biosynthetic process 1
                positive regulation of citrulline biosynthetic process 0
                regulation of citrulline biosynthetic process + 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              carboxylic acid biosynthetic process 318
                cellular amino acid biosynthetic process 71
                  alpha-amino acid biosynthetic process 66
                    citrulline biosynthetic process 4
                      negative regulation of citrulline biosynthetic process 1
                      positive regulation of citrulline biosynthetic process 0
                      regulation of citrulline biosynthetic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.