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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:cytokine-mediated signaling pathway
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Accession:GO:0019221 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: cytokine and chemokine mediated signaling pathway;   cytokine mediated signalling pathway


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cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:14967141)		 Ensembl
RGD		 PMID:14967141 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Cav1 caveolin 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2180364 (PMID:12388746)		 Ensembl
RGD		 PMID:12388746 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in IMP
ISO		 (PMID:12207323) RGD PMID:12207323 PMID:16174730 RGD:1625370 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 acts_upstream_of_or_within IMP
ISO		 (PMID:15995708) RGD PMID:15995708 PMID:16174730 RGD:1625370 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd44 CD44 molecule involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cish cytokine inducible SH2-containing protein IEP RGD PMID:10579313 RGD:724748 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 acts_upstream_of_or_within ISO (PMID:10880228) RGD PMID:10880228 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100 		JBrowse link
G Cntfr ciliary neurotrophic factor receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 involved_in ISO (PMID:11418668) RGD PMID:11418668 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO
IEA		 (PMID:20504948)
GO_REF:0000002		 RGD
InterPro		 PMID:20504948 GO_REF:0000002 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csf3r colony stimulating factor 3 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO (PMID:18971423) RGD PMID:18971423 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Duox1 dual oxidase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16111680)		 UniProt
Ensembl
RGD		 PMID:16111680 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16111680)		 UniProt
RGD		 PMID:16111680 GO_REF:0000024 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544 		JBrowse link
G Eda ectodysplasin-A involved_in ISO (PMID:27144394)
(PMID:11039935)		 RGD PMID:11039935 PMID:27144394 NCBI chr  X:65,078,454...65,480,172
Ensembl chr  X:65,078,673...65,480,172 		JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in ISO (PMID:11039935) RGD PMID:11039935 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Edar ectodysplasin-A receptor involved_in ISO MGI:1856016 (PMID:19619491)
(PMID:11039935)		 RGD PMID:11039935 PMID:19619491 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Edn2 endothelin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12207323)		 Ensembl
RGD		 PMID:12207323 GO_REF:0000107 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G ENSRNOG00000062907 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 1:65,368,464...65,375,989 JBrowse link
G ENSRNOG00000064524 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 1:65,352,351...65,359,807 JBrowse link
G ENSRNOG00000067708 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 1:70,285,453...70,305,234 JBrowse link
G Epor erythropoietin receptor involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Ereg epiregulin involved_in ISO
ISS		 (PMID:9419975)
GO_REF:0000024		 RGD
UniProt		 PMID:9419975 GO_REF:0000024 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:9722593)		 UniProt
RGD		 PMID:9722593 GO_REF:0000024 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A acts_upstream_of_or_within ISO MGI:2158807 (PMID:14605212) RGD PMID:14605212 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 involved_in ISO
IBA		 (MGI:3795633|PMID:18469816)
GO_REF:0000033		 RGD
GO_Central		 PMID:18469816 GO_REF:0000033 MGI:3795633 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:3055991 (PMID:30990796) RGD PMID:30990796 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fzd4 frizzled class receptor 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Gh1 growth hormone 1 involved_in ISO (PMID:7782332) RGD PMID:7782332 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Ghr growth hormone receptor involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000108		 GO_Central
GOC		 GO_REF:0000033 GO_REF:0000108 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in ISO (MGI:5543884|PMID:23850456) RGD PMID:23850456 MGI:5543884 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615 		JBrowse link
G Ifna12l interferon alpha 12 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,476,362...103,477,427
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052 		JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO
IBA		 (PMID:6157094), (PMID:7813427)
GO_REF:0000033		 RGD
GO_Central		 PMID:6157094 PMID:7813427 GO_REF:0000033 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ifngr2 interferon gamma receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Ifnk interferon kappa involved_in ISO
IBA		 (PMID:11514542)
GO_REF:0000033		 RGD
GO_Central		 PMID:11514542 GO_REF:0000033 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281 		JBrowse link
G Ifnlr1 interferon, lambda receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:147,919,547...147,942,328
Ensembl chr 5:147,919,908...147,942,332 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2182946 (MGI:1196700|PMID:9463407)
GO_REF:0000033		 RGD
GO_Central		 PMID:9463407 GO_REF:0000033 MGI:1196700 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:7957045)		 GO_Central
RGD		 PMID:7957045 GO_REF:0000033 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408 		JBrowse link
G Il12b interleukin 12B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il13ra1-ps1 interleukin 13 receptor subunit alpha 1, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:71,255,035...71,258,723
Ensembl chr11:71,254,928...71,258,678 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il16 interleukin 16 involved_in ISO (MGI:6414686|PMID:30089723) RGD PMID:30089723 MGI:6414686 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il17rb interleukin 17 receptor B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125 		JBrowse link
G Il17rd interleukin 17 receptor D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Il17re interleukin 17 receptor E involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206 		JBrowse link
G Il18 interleukin 18 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha involved_in ISO
IBA
IEA		 (PMID:2989698)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:2989698 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IBA
IEA		 (PMID:10748004)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:10748004 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1f10 interleukin 1 family member 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 acts_upstream_of_or_within ISO (PMID:11880380), (PMID:15292196) RGD PMID:11880380 PMID:15292196 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(PMID:11880380)		 GOC
RGD		 PMID:11880380 GO_REF:0000108 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rapl2 interleukin 1 receptor accessory protein-like 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:100,961,509...102,271,753
Ensembl chr  X:100,961,812...102,271,753 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il20ra interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5302406 (PMID:21844205)		 GO_Central
RGD		 PMID:21844205 GO_REF:0000033 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Il21r interleukin 21 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522 		JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844 		JBrowse link
G Il23r interleukin 23 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta involved_in
acts_upstream_of_or_within		 IEP
IBA
ISO		 GO_REF:0000033
(PMID:7736574)		 GO_Central
RGD		 PMID:7736574 PMID:1889461 GO_REF:0000033, RGD:728928 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:7519779) RGD PMID:7519779 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il31ra interleukin 31 receptor A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:44,118,748...44,189,943
Ensembl chr 2:44,122,624...44,183,767 		JBrowse link
G Il36a interleukin 36, alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400 		JBrowse link
G Il36b interleukin 36, beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:7,024,881...7,030,388
Ensembl chr 3:7,021,973...7,031,619 		JBrowse link
G Il36g interleukin 36, gamma involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il3ra interleukin 3 receptor subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484 		JBrowse link
G Il4r interleukin 4 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5 interleukin 5 IDA
IMP		 RGD PMID:11335106 PMID:10867506 RGD:2303510, RGD:2303751 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:12643274), (PMID:2261637) RGD PMID:2261637 PMID:12643274 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (PMID:2261637) RGD PMID:2261637 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:2261637)
GO_REF:0000033
(PMID:7957045)
GO_REF:0000108		 RGD
GO_Central
GOC		 PMID:2261637 PMID:7957045 GO_REF:0000033 GO_REF:0000108 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Il7 interleukin 7 involved_in ISO
IEA		 (PMID:11418668)
GO_REF:0000107		 RGD
Ensembl		 PMID:11418668 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Il7r interleukin 7 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Il9r interleukin 9 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990 		JBrowse link
G Inhba inhibin subunit beta A IEP RGD PMID:14993131 RGD:1580888 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Insl3 insulin-like 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 acts_upstream_of_or_within IMP
ISO		 (PMID:15292196) RGD PMID:15292196 PMID:15890643 RGD:1579817 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2181508|PMID:12054681) RGD PMID:12054681 MGI:2181508 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 (PMID:15292196)
GO_REF:0000033		 RGD
GO_Central		 PMID:15292196 PMID:15890643 GO_REF:0000033, RGD:1579817 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:25326418)
(MGI:3575850|PMID:15665823), (MGI:5609199|PMID:25326420)		 RGD PMID:15665823 PMID:25326418 PMID:25326420 MGI:3575850 MGI:5609199 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P01241 (PMID:7782332)		 Ensembl
RGD		 PMID:7782332 GO_REF:0000107 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Jak1 Janus kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:8022486)		 GO_Central
RGD		 PMID:8022486 GO_REF:0000033 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO
IBA
IEA
ISS		 (PMID:8609418)
GO_REF:0000033
UniProtKB:P01241 (MGI:1203273|PMID:9590174), (MGI:1203274|PMID:9590173), (MGI:3828423|PMID:7782332)
GO_REF:0000117
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:7782332 PMID:8609418 PMID:9590173 PMID:9590174 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 MGI:1203273 MGI:1203274 MGI:3828423 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jak3 Janus kinase 3 acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 (PMID:8022486)
GO_REF:0000033		 RGD
GO_Central		 PMID:8022486 PMID:7518451 GO_REF:0000033, RGD:1600268 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 ISO (PMID:21640708)
(PMID:10872802)		 RGD PMID:10872802 PMID:21640708 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf6 KLF transcription factor 6 acts_upstream_of_or_within ISO (PMID:10880228) RGD PMID:10880228 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lepr leptin receptor involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lifr LIF receptor subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:7957045)
GO_REF:0000033
GO_REF:0000108		 RGD
GO_Central
GOC		 PMID:7957045 GO_REF:0000033 GO_REF:0000108 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718 		JBrowse link
G Lilrb1 leukocyte immunoglobulin like receptor B1 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:65,457,264...65,464,523
Ensembl chr 1:65,457,534...65,464,520 		JBrowse link
G Lilrb2 leukocyte immunoglobulin like receptor B2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:65,326,832...65,334,683
Ensembl chr 1:65,326,832...65,334,679 		JBrowse link
G Lilrb3 leukocyte immunoglobulin like receptor B3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:69,928,948...69,939,461
Ensembl chr 1:69,928,945...69,939,048 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lilrc2 leukocyte immunoglobulin-like receptor, subfamily C, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:65,272,134...65,277,278
Ensembl chr 1:65,272,796...65,277,271 		JBrowse link
G LOC120103163 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,494,442...103,495,077
Ensembl chr 5:103,494,448...103,495,002 		JBrowse link
G LOC120103164 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,509,610...103,510,260
Ensembl chr 5:103,509,616...103,510,170 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IMP RGD PMID:15890643 RGD:1579817 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:5501251 (PMID:30224457), (PMID:31622280) RGD PMID:30224457 PMID:31622280 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein involved_in ISO
IEA
ISS		 (PMID:18299187)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18299187 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776 		JBrowse link
G Osmr oncostatin M receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Pf4 platelet factor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12041672)		 UniProt
RGD		 PMID:12041672 GO_REF:0000024 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO UniProtKB:P01241 (PMID:7782332) RGD PMID:7782332 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pira2 paired-Ig-like receptor A2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:65,352,125...65,422,842
Ensembl chr 1:65,415,946...65,422,853 		JBrowse link
G Pirb paired Ig-like receptor B involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:2180757 (PMID:12021780)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:12021780 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Prlr prolactin receptor involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:15876188) RGD PMID:15876188 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of ISO MGI:2446070 (PMID:11894097) RGD PMID:11894097 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 acts_upstream_of_or_within ISO (PMID:10872802) RGD PMID:10872802 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:28886095) RGD PMID:28886095 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2177057 (PMID:11606785), (PMID:9202126), (PMID:9202127)		 Ensembl
RGD		 PMID:9202126 PMID:9202127 PMID:11606785 GO_REF:0000107 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:3687909 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO (PMID:12872135) RGD PMID:12872135 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 acts_upstream_of_or_within ISO (PMID:11894097), (PMID:12213961) RGD PMID:11894097 PMID:12213961 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000118
(PMID:10485657)
GO_REF:0000033		 TreeGrafter
RGD
GO_Central		 PMID:10485657 GO_REF:0000033 GO_REF:0000118 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:10485657)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:10485657 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in IMP
ISO
IBA		 (PMID:36884218)
GO_REF:0000033		 RGD
GO_Central		 PMID:36884218 PMID:18362439 GO_REF:0000033, RGD:2298568 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1861040 (PMID:11588035)		 UniProt
RGD		 PMID:11588035 GO_REF:0000024 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (PMID:15248232) RGD PMID:15248232 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3831153 (PMID:19155511) RGD PMID:19155511 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf6 TNF receptor associated factor 6 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
G Zc3h15 zinc finger CCCH-type containing 15 acts_upstream_of_or_within ISO (PMID:10880228) RGD PMID:10880228 NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333 		JBrowse link
adiponectin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 acts_upstream_of_or_within ISO (PMID:20667975) RGD PMID:20667975 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Adipor1 adiponectin receptor 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 (PMID:12802337)
GO_REF:0000033
(MGI:5607379|PMID:24742672)		 RGD
GO_Central		 PMID:12802337 PMID:24742672 PMID:18394428 GO_REF:0000033 MGI:5607379, RGD:2317907 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Adipor2 adiponectin receptor 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:12802337)
GO_REF:0000033
(MGI:5607379|PMID:24742672)		 RGD
GO_Central		 PMID:12802337 PMID:24742672 GO_REF:0000033 MGI:5607379 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:19661063) RGD PMID:19661063 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) RGD PMID:19661063 MGI:4420367 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO
IEA		 (PMID:19233263)
GO_REF:0000107		 RGD
Ensembl		 PMID:19233263 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20667975)
GO_REF:0000118		 Ensembl
RGD
TreeGrafter		 PMID:20667975 GO_REF:0000107 GO_REF:0000118 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
C-X-C chemokine receptor CXCR4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:16467205) RGD PMID:16467205 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
chemokine (C-C motif) ligand 19 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
chemokine (C-C motif) ligand 21 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (MGI:6141968|PMID:27400149) RGD PMID:27400149 MGI:6141968 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) RGD PMID:27400149 MGI:6141968 NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO
IEA		 (MGI:6141968|PMID:27400149)
GO_REF:0000107		 RGD
Ensembl		 PMID:27400149 GO_REF:0000107 MGI:6141968 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
chemokine (C-X-C motif) ligand 12 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:27400149) RGD PMID:27400149 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 involved_in ISO (PMID:27400149) RGD PMID:27400149 NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (PMID:27400149) RGD PMID:27400149 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr1 atypical chemokine receptor 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:85,782,396...85,784,015
Ensembl chr13:85,782,398...85,783,983 		JBrowse link
G Ackr2 atypical chemokine receptor 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582 		JBrowse link
G Ackr3 atypical chemokine receptor 3 involved_in ISO (PMID:20388803) RGD PMID:20388803 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Ackr4 atypical chemokine receptor 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:104,716,537...104,720,972
Ensembl chr 8:104,716,067...104,723,617 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:18584881 GO_REF:0000033, RGD:2303073 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 involved_in ISO
IBA		 (PMID:10373330)
GO_REF:0000033		 RGD
GO_Central		 PMID:10373330 GO_REF:0000033 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO
IBA
ISS		 (PMID:17001303)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:17001303 GO_REF:0000024 GO_REF:0000033 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:68,380,185...68,385,859
Ensembl chr10:68,380,188...68,384,001 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr10 C-C motif chemokine receptor 10 acts_upstream_of_or_within ISO (MGI:1354873|PMID:10725696) RGD PMID:10725696 MGI:1354873 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988 		JBrowse link
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 acts_upstream_of_or_within IMP
ISO		 (MGI:79768|PMID:8631787) RGD PMID:8631787 PMID:18584881 MGI:79768, RGD:2303073 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(MGI:77397|PMID:7594543)		 GOC
RGD		 PMID:7594543 GO_REF:0000108 MGI:77397 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969 		JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IGI
IBA
ISO		 PMID:12729461
GO_REF:0000033
UniProtKB:P35411 (PMID:10415068), (PMID:10869418)		 GO_Central
RGD		 PMID:10415068 PMID:10869418 PMID:12729461 GO_REF:0000033, RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IMP
IGI		 PMID:10415068
PMID:12729461
PMID:10869418		 ARUK-UCL PMID:10415068 PMID:12729461 PMID:10869418 RGD:13673824, RGD:13673777, RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
IBA		 (PMID:18645041)
GO_REF:0000033		 RGD
GO_Central		 PMID:18645041 GO_REF:0000033 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO
IBA		 (PMID:18645041)
GO_REF:0000033		 RGD
GO_Central		 PMID:18645041 GO_REF:0000033 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO
IBA		 (PMID:20388803)
GO_REF:0000033		 RGD
GO_Central		 PMID:20388803 GO_REF:0000033 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 acts_upstream_of_or_within ISO (MGI:1891794|PMID:11017100) RGD PMID:11017100 MGI:1891794 NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (MGI:3773495|PMID:18187037) RGD PMID:18187037 MGI:3773495 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Gpr35 G protein-coupled receptor 35 involved_in ISO
ISS		 (PMID:25411203)
GO_REF:0000024		 RGD
UniProt		 PMID:25411203 GO_REF:0000024 NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299 		JBrowse link
G Gpr75 G protein-coupled receptor 75 involved_in ISO (MGI:5582173|PMID:17001303) RGD PMID:17001303 MGI:5582173 NCBI chr14:104,609,542...104,618,885
Ensembl chr14:104,611,089...104,620,370 		JBrowse link
G Pf4 platelet factor 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Ppbp pro-platelet basic protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:3583523|PMID:12960403)		 UniProt
RGD		 PMID:12960403 GO_REF:0000024 MGI:3583523 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Tff2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:103556 (PMID:19064997)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:19064997 GO_REF:0000033 GO_REF:0000118 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
G Xcr1 X-C motif chemokine receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226 		JBrowse link
ciliary neurotrophic factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:12643274)		 Ensembl
GO_Central
RGD		 PMID:12643274 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Cntfr ciliary neurotrophic factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:88439 (PMID:7585948)
GO_REF:0000033
(PMID:12643274)		 Ensembl
RGD
GO_Central		 PMID:7585948 PMID:12643274 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA		 (PMID:12643274)
GO_REF:0000107		 RGD
Ensembl		 PMID:12643274 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 (PMID:12643274)
GO_REF:0000107		 RGD
Ensembl		 PMID:12643274 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Lifr LIF receptor subunit alpha involved_in ISO
IEA		 (PMID:12643274)
GO_REF:0000107		 RGD
Ensembl		 PMID:12643274 GO_REF:0000107 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
CXCL12-activated CXCR4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO UniProtKB:P61073 (PMID:27693460) RGD PMID:27693460 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:31845480)
UniProtKB:P48061 (PMID:24912431), (PMID:27693460), (PMID:28978524)		 UniProt
RGD		 PMID:24912431 PMID:27693460 PMID:28978524 PMID:31845480 GO_REF:0000024 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 involved_in ISO (PMID:34927784) RGD PMID:34927784 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within_positive_effect ISO (PMID:33097708) RGD PMID:33097708 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Wbp1l WW domain binding protein 1-like acts_upstream_of_or_within ISO (PMID:31845480) RGD PMID:31845480 NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627 		JBrowse link
erythropoietin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:28283061)		 UniProt
GO_Central
RGD		 PMID:28283061 GO_REF:0000024 GO_REF:0000033 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:5430888|PMID:18538998) RGD PMID:18538998 MGI:5430888 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
granulocyte colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4837548|PMID:21029969)		 UniProt
RGD		 PMID:21029969 GO_REF:0000024 MGI:4837548 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Csf3 colony stimulating factor 3 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Hax1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Jagn1 jagunal homolog 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:5604054|PMID:25129145)
(PMID:25129144)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:25129144 PMID:25129145 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5604054 NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288 		JBrowse link
granulocyte-macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:18692472) RGD PMID:18692472 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha involved_in ISO (PMID:18692472) RGD PMID:18692472 NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta involved_in ISO (PMID:18692472) RGD PMID:18692472 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:18692472) RGD PMID:18692472 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20018936)		 Ensembl
RGD		 PMID:20018936 GO_REF:0000107 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:1919436), (PMID:25327529), (PMID:28331908), (PMID:2950091), (PMID:32719155), (PMID:33377178) RGD PMID:1919436 PMID:2950091 PMID:25327529 PMID:28331908 PMID:32719155 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in IMP
IEA
IBA
ISO		 GO_REF:0000108
GO_REF:0000033
GO_REF:0000118
(PMID:10383454), (PMID:2950091)
(MGI:1889886|PMID:10854325)		 GOC
GO_Central
TreeGrafter
RGD		 PMID:2950091 PMID:10383454 PMID:10854325 PMID:20967881 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 MGI:1889886, RGD:5130945 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:9065432)		 Ensembl
RGD		 PMID:9065432 GO_REF:0000107 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 NOT|involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11397809)
(PMID:12054681)
GO_REF:0000033
(PMID:10383454), (PMID:14625308)
(MGI:1889886|PMID:10854325)		 RGD
GO_Central		 PMID:10383454 PMID:10854325 PMID:11397809 PMID:12054681 PMID:14625308 GO_REF:0000033 MGI:1889886 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in ISO
IBA
IEA		 (PMID:10383454)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:10383454 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10383454)
(PMID:12054681)
GO_REF:0000033		 RGD
GO_Central		 PMID:10383454 PMID:12054681 GO_REF:0000033 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in ISO (PMID:20485341) RGD PMID:20485341 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:10094049) RGD PMID:10094049 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir146a microRNA 146a involved_in ISO (PMID:20937840) RGD PMID:20937840 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (MGI:1889886|PMID:10854325)
(PMID:9430229)		 RGD PMID:9430229 PMID:10854325 MGI:1889886 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:26020802) RGD PMID:26020802 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8872139)		 Ensembl
RGD		 PMID:8872139 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 1:204,021,805...204,032,781
Ensembl chr 1:204,021,806...204,032,761 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 involved_in ISO (PMID:20018936) RGD PMID:20018936 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor involved_in ISO
IEA		 (PMID:18676404)
GO_REF:0000107		 RGD
Ensembl		 PMID:18676404 GO_REF:0000107 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:2149909|PMID:11544529) RGD PMID:11544529 MGI:2149909 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) RGD PMID:16633345 MGI:3656197 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tollip toll interacting protein involved_in ISO (MGI:1889886|PMID:10854325)
(PMID:10854325)		 RGD PMID:10854325 MGI:1889886 NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IMP
IEA
ISO		 GO_REF:0000107
(MGI:2181820|PMID:10421844)		 Ensembl
RGD		 PMID:10421844 PMID:20967881 GO_REF:0000107 MGI:2181820, RGD:5130945 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
interleukin-10-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO (PMID:24994464) RGD PMID:24994464 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:16982608) RGD PMID:16982608 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta involved_in ISO (PMID:16982608) RGD PMID:16982608 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:7543512) RGD PMID:7543512 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:17163451) RGD PMID:17163451 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:7543512) RGD PMID:7543512 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:7543512) RGD PMID:7543512 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
interleukin-11-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il11 interleukin 11 involved_in IEA
ISO		 GO_REF:0000107
(PMID:33397952)		 Ensembl
RGD		 PMID:33397952 GO_REF:0000107 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 involved_in ISO
IEA		 (PMID:8637716)
GO_REF:0000107		 RGD
Ensembl		 PMID:8637716 GO_REF:0000107 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408 		JBrowse link
G Il6r interleukin 6 receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in IEA
ISO		 GO_REF:0000107
(PMID:8637716)		 Ensembl
RGD		 PMID:8637716 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:8272872) RGD PMID:8272872 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 (PMID:28781374)
GO_REF:0000107		 RGD
Ensembl		 PMID:28781374 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
interleukin-12-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:10899108), (PMID:7584494)
GO_REF:0000107		 RGD
Ensembl		 PMID:7584494 PMID:10899108 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7584494) RGD PMID:7584494 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:8943050) RGD PMID:8943050 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 involved_in ISO (PMID:8943050) RGD PMID:8943050 NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:7528775) RGD PMID:7528775 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11743656)		 Ensembl
RGD		 PMID:11743656 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in ISO (PMID:7638186) RGD PMID:7638186 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:7528775) RGD PMID:7528775 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
interleukin-13-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(MGI:5660125|PMID:26124135)		 UniProt
RGD		 PMID:26124135 GO_REF:0000024 MGI:5660125 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il13ra1-ps1 interleukin 13 receptor subunit alpha 1, pseudogene 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:71,255,035...71,258,723
Ensembl chr11:71,254,928...71,258,678 		JBrowse link
interleukin-15-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd4 Cd4 molecule involved_in ISO
IBA		 (PMID:24942581)
GO_REF:0000033		 RGD
GO_Central		 PMID:24942581 GO_REF:0000033 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Il15 interleukin 15 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15123770), (PMID:24942581), (PMID:9097905)		 UniProt
Ensembl
RGD		 PMID:9097905 PMID:15123770 PMID:24942581 GO_REF:0000024 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha involved_in ISO
IBA		 (PMID:15123770)
GO_REF:0000033		 RGD
GO_Central		 PMID:15123770 GO_REF:0000033 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15123770), (PMID:31040184)		 Ensembl
UniProt
RGD		 PMID:15123770 PMID:31040184 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:15123770) RGD PMID:15123770 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:7568001) RGD PMID:7568001 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO
IEA		 (PMID:7568001)
GO_REF:0000107		 RGD
Ensembl		 PMID:7568001 GO_REF:0000107 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Mfap3 microfibril associated protein 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:41,696,788...41,711,490
Ensembl chr10:41,696,771...41,710,406 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA		 (PMID:11743656)
GO_REF:0000107		 RGD
Ensembl		 PMID:11743656 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 (PMID:7568001)
GO_REF:0000107		 RGD
Ensembl		 PMID:7568001 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:7568001)		 Ensembl
RGD		 PMID:7568001 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:21822257) RGD PMID:21822257 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Il17a interleukin 17A involved_in ISO
IEA		 (PMID:21350122)
GO_REF:0000107		 RGD
Ensembl		 PMID:21350122 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17f interleukin 17F involved_in ISO
IEA		 (PMID:21350122)
GO_REF:0000107		 RGD
Ensembl		 PMID:21350122 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
G Il17ra interleukin 17 receptor A involved_in ISO (PMID:21350122), (PMID:33723527)
(MGI:6694386|PMID:33723527), (PMID:19825828), (PMID:28561022)		 RGD PMID:19825828 PMID:21350122 PMID:28561022 PMID:33723527 MGI:6694386 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:28561022) RGD PMID:28561022 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 involved_in ISO (PMID:21822258) RGD PMID:21822258 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:21822258) RGD PMID:21822258 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO (PMID:19825828), (PMID:24120361)
MGI:3510784|MGI:4820827 (PMID:19155512), (PMID:19825828), (PMID:20303295), (PMID:20660351), (PMID:21822257), (PMID:21822258), (PMID:23995070), (PMID:28561022)		 RGD PMID:19155512 PMID:19825828 PMID:20303295 PMID:20660351 PMID:21822257 More... NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in ISO (PMID:21822258) RGD PMID:21822258 NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19825828)		 Ensembl
RGD		 PMID:19825828 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO MGI:4332130 (PMID:23042150) RGD PMID:23042150 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
interleukin-17A-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in IEA
ISO		 GO_REF:0000107
(PMID:12297109)		 Ensembl
RGD		 PMID:12297109 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17ra interleukin 17 receptor A involved_in ISO (PMID:9367539) RGD PMID:9367539 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Il17rc interleukin 17 receptor C involved_in ISO (PMID:20554964) RGD PMID:20554964 NCBI chr 4:146,618,321...146,631,444
Ensembl chr 4:146,619,004...146,631,442 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:31376257) RGD PMID:31376257 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO (PMID:17277779), (PMID:19825828)
MGI:3510784|MGI:3831153 (PMID:17277779), (PMID:19155511)		 RGD PMID:17277779 PMID:19155511 PMID:19825828 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:35183823)
GO_REF:0000107		 RGD
Ensembl		 PMID:35183823 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:21321938)
GO_REF:0000107		 RGD
Ensembl		 PMID:21321938 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Il18 interleukin 18 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:15843532)
(PMID:14528293), (PMID:21321938), (PMID:25500532), (PMID:37993714)
(MGI:6259277|PMID:30392956)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14528293 PMID:15843532 PMID:21321938 PMID:25500532 PMID:30392956 More... GO_REF:0000024 GO_REF:0000107 MGI:6259277 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:25500532)
MGI:2136765 (PMID:10227969)
GO_REF:0000033		 RGD
GO_Central		 PMID:10227969 PMID:25500532 GO_REF:0000033 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:25500532)
MGI:3579137 (PMID:15843532)
GO_REF:0000033		 RGD
GO_Central		 PMID:15843532 PMID:25500532 GO_REF:0000033 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
IEA		 (PMID:21321938)
GO_REF:0000107		 RGD
Ensembl		 PMID:21321938 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21321938)		 Ensembl
RGD		 PMID:21321938 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
interleukin-2-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 involved_in ISO (PMID:22844114) RGD PMID:22844114 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha involved_in ISO (PMID:16293754) RGD PMID:16293754 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:31040184), (PMID:7973659)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:7973659 PMID:31040184 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:7568005) RGD PMID:7568005 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:11909529), (PMID:7973659) RGD PMID:7973659 PMID:11909529 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO
IEA		 (PMID:7973659)
GO_REF:0000107		 RGD
Ensembl		 PMID:7973659 GO_REF:0000107 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 (PMID:7568005)
GO_REF:0000107		 RGD
Ensembl		 PMID:7568005 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:8631883)		 Ensembl
RGD		 PMID:8631883 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
interleukin-22-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar2 interferon alpha and beta receptor subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124 		JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844 		JBrowse link
interleukin-23-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il23r interleukin 23 receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021 		JBrowse link
G Mir301a microRNA 301a acts_upstream_of_or_within ISO (PMID:22517757) RGD PMID:22517757 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
interleukin-27-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27ra interleukin 27 receptor subunit alpha involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 (PMID:14764690)
GO_REF:0000107		 RGD
Ensembl		 PMID:14764690 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Mx1 MX dynamin like GTPase 1 involved_in ISO (PMID:32270034) RGD PMID:32270034 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:32270034) RGD PMID:32270034 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in ISO
IEA		 (PMID:32270034)
(MGI:6415954|PMID:32270034)
GO_REF:0000107		 RGD
Ensembl		 PMID:32270034 GO_REF:0000107 MGI:6415954 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in ISO (PMID:32270034)
(MGI:6415954|PMID:32270034)		 RGD PMID:32270034 MGI:6415954 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:32270034) RGD PMID:32270034 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
interleukin-3-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2rb colony stimulating factor 2 receptor subunit beta involved_in ISO (PMID:8649415) RGD PMID:8649415 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in ISS
ISO		 GO_REF:0000024
(MGI:3831068|PMID:19098920)		 UniProt
RGD		 PMID:19098920 GO_REF:0000024 MGI:3831068 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Il3 interleukin 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:35281014)
(PMID:19109256)		 RGD PMID:19109256 PMID:35281014 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il3ra interleukin 3 receptor subunit alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:8649415)
(PMID:19109256)		 RGD PMID:8649415 PMID:19109256 NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:8007942) RGD PMID:8007942 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:22102340)		 Ensembl
RGD		 PMID:22102340 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3831068|PMID:19098920)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19098920 GO_REF:0000024 GO_REF:0000107 MGI:3831068 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
interleukin-33-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rap interleukin 1 receptor accessory protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:17675517)
(MGI:3764000|PMID:18003919), (MGI:4353496|PMID:17675517)		 Ensembl
RGD		 PMID:17675517 PMID:18003919 GO_REF:0000107 MGI:3764000 MGI:4353496 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 involved_in ISO
IEA		 (PMID:16286016)
GO_REF:0000107		 RGD
Ensembl		 PMID:16286016 GO_REF:0000107 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6414704|PMID:26936882)		 Ensembl
RGD		 PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:31435003) RGD PMID:31435003 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in ISO (PMID:11960013) RGD PMID:11960013 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:20532808) RGD PMID:20532808 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:18802081) RGD PMID:18802081 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:31435003)
GO_REF:0000107		 RGD
Ensembl		 PMID:31435003 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
interleukin-34-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il34 interleukin 34 involved_in ISO
IEA		 (PMID:26754294)
GO_REF:0000107		 RGD
Ensembl		 PMID:26754294 GO_REF:0000107 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000 		JBrowse link
interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 involved_in ISO
IBA		 (PMID:10219247)
GO_REF:0000033		 RGD
GO_Central		 PMID:10219247 GO_REF:0000033 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor involved_in ISO
IEA		 (PMID:10219247)
GO_REF:0000107		 RGD
Ensembl		 PMID:10219247 GO_REF:0000107 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:7929391) RGD PMID:7929391 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO
IEA		 (PMID:7538655)
GO_REF:0000107
(PMID:24280217)		 RGD
Ensembl		 PMID:7538655 PMID:24280217 GO_REF:0000107 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:17200144)		 Ensembl
RGD		 PMID:17200144 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in ISO (PMID:24280217)
(PMID:17210636), (PMID:36758835), (PMID:7760829)
(MGI:5493214|PMID:17210636)		 RGD PMID:7760829 PMID:17210636 PMID:24280217 PMID:36758835 MGI:5493214 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
interleukin-5-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2rb colony stimulating factor 2 receptor subunit beta involved_in ISO (PMID:1495999) RGD PMID:1495999 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Il5 interleukin 5 involved_in ISO (PMID:33099778) RGD PMID:33099778 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha involved_in ISO (PMID:22528658) RGD PMID:22528658 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:7613138) RGD PMID:7613138 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:11823534) RGD PMID:11823534 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:12393707)		 Ensembl
RGD		 PMID:12393707 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpa CCAAT/enhancer binding protein alpha involved_in ISO (PMID:24429361) RGD PMID:24429361 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:5319608|PMID:17911113) RGD PMID:17911113 MGI:5319608 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303 		JBrowse link
G Fer FER tyrosine kinase involved_in ISO (PMID:19147545) RGD PMID:19147545 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within ISO MGI:1926435 (PMID:10779359) RGD PMID:10779359 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Il6 interleukin 6 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:1312474)
(PMID:12552091), (PMID:12829785), (PMID:16946298), (PMID:30670152), (PMID:31145836)
(MGI:3769957|PMID:16330325), (MGI:6142555|PMID:27893700), (MGI:84432|PMID:8910279)		 UniProt
RGD		 PMID:1312474 PMID:8910279 PMID:12552091 PMID:12829785 PMID:16330325 More... GO_REF:0000024 MGI:3769957 MGI:6142555 MGI:84432 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:1312474)
GO_REF:0000033
(PMID:31145836)
(PMID:12829785)
GO_REF:0000107
(MGI:6142555|PMID:27893700)
(PMID:12643274)		 UniProt
RGD
GO_Central
Ensembl		 PMID:1312474 PMID:12643274 PMID:12829785 PMID:27893700 PMID:31145836 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:6142555 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in IMP
ISO
IEA		 (PMID:12643274), (PMID:12829785), (PMID:2261637), (PMID:25731159)
GO_REF:0000107
(MGI:5629863|PMID:25731159)		 RGD
Ensembl		 PMID:2261637 PMID:12643274 PMID:12829785 PMID:25731159 PMID:18280048 GO_REF:0000107 MGI:5629863, RGD:5686900 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:8272873) RGD PMID:8272873 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Smad4 SMAD family member 4 involved_in ISO
IEA		 (MGI:3769957|PMID:16330325)
GO_REF:0000107		 RGD
Ensembl		 PMID:16330325 GO_REF:0000107 MGI:3769957 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA		 (PMID:24429361)
GO_REF:0000107		 RGD
Ensembl		 PMID:24429361 GO_REF:0000107 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:25731159)
(MGI:5629863|PMID:25731159)		 RGD PMID:25731159 MGI:5629863 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor involved_in ISO
IEA		 (PMID:18676404)
GO_REF:0000107		 RGD
Ensembl		 PMID:18676404 GO_REF:0000107 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12359225), (PMID:12552091), (PMID:16285960), (PMID:16835372), (PMID:16946298), (PMID:17324931), (PMID:24429361)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12359225 PMID:12552091 PMID:16285960 PMID:16835372 PMID:16946298 More... GO_REF:0000024 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tut4 terminal uridylyl transferase 4 involved_in ISO (MGI:4365679|PMID:19701194) RGD PMID:19701194 MGI:4365679 NCBI chr 5:123,201,723...123,306,582
Ensembl chr 5:123,203,003...123,306,465 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO
IEA		 (MGI:5629863|PMID:25731159)
GO_REF:0000107		 RGD
Ensembl		 PMID:25731159 GO_REF:0000107 MGI:5629863 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
interleukin-7-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:8128231) RGD PMID:8128231 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il7 interleukin 7 involved_in ISO (PMID:25870237) RGD PMID:25870237 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Il7r interleukin 7 receptor involved_in ISO (PMID:8128231) RGD PMID:8128231 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO (PMID:11480573) RGD PMID:11480573 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
interleukin-8-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr1 C-X-C motif chemokine receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 involved_in ISO (PMID:10820279) RGD PMID:10820279 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
interleukin-9-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:18829468) RGD PMID:18829468 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il9r interleukin 9 receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:8756628)
MGI:96563 (MGI:6506914|PMID:30082831)		 RGD PMID:8756628 PMID:30082831 MGI:6506914 NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:8756628) RGD PMID:8756628 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO
IEA		 (PMID:18829468)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829468 GO_REF:0000107 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:9535918) RGD PMID:9535918 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 (PMID:9535918)
GO_REF:0000107		 RGD
Ensembl		 PMID:9535918 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:10919676)		 Ensembl
RGD		 PMID:10919676 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
Kit signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fer FER tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:2385502|PMID:12192036)		 UniProt
RGD		 PMID:12192036 GO_REF:0000024 MGI:2385502 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO
IBA		 (PMID:17662946)
GO_REF:0000033		 RGD
GO_Central		 PMID:17662946 GO_REF:0000033 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of ISO MGI:3051384 (PMID:16533754) RGD PMID:16533754 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
leptin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 IMP RGD PMID:18394428 RGD:2317907 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 acts_upstream_of_or_within ISO MGI:3521669 (PMID:19150989) RGD PMID:19150989 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within ISO MGI:3045473 (PMID:19150989) RGD PMID:19150989 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Lep leptin involved_in IDA
ISO		 (MGI:5700303|PMID:16825198)
PMID:11677594		 RGD PMID:16825198 PMID:9070213 PMID:11677594 PMID:9618284 MGI:5700303, RGD:2290293, RGD:10448951, RGD:2290294 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor involved_in IDA
IEA
ISO		 GO_REF:0000107
(MGI:2652302|PMID:12594516)
(PMID:27037668)		 Ensembl
RGD		 PMID:12594516 PMID:27037668 PMID:9070213 PMID:9618284 GO_REF:0000107 MGI:2652302, RGD:2290293, RGD:2290294 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lepr_v1 leptin receptor, variant 1 IDA RGD PMID:9070213 PMID:9618284 RGD:2290293, RGD:2290294
G Lepr_v2 leptin receptor, variant 2 IDA RGD PMID:9070213 PMID:9618284 RGD:2290293, RGD:2290294
G Mkks MKKS centrosomal shuttling protein acts_upstream_of_or_within ISO MGI:3526444 (PMID:19150989) RGD PMID:19150989 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5299282|PMID:21726645)		 UniProt
RGD		 PMID:21726645 GO_REF:0000024 MGI:5299282 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:4821191|PMID:20620997)
GO_REF:0000107		 RGD
Ensembl		 PMID:20620997 GO_REF:0000107 MGI:4821191 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:2652302|PMID:12594516), (MGI:5700303|PMID:16825198)
(PMID:17344214)		 UniProt
GO_Central
Ensembl
RGD		 PMID:12594516 PMID:16825198 PMID:17344214 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:2652302 MGI:5700303 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5634638|PMID:23554574)		 UniProt
RGD		 PMID:23554574 GO_REF:0000024 MGI:5634638 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1 colony stimulating factor 1 involved_in ISO (MGI:3836228|PMID:19017797) RGD PMID:19017797 MGI:3836228 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:3831067|PMID:19100238), (MGI:3836228|PMID:19017797)		 Ensembl
RGD		 PMID:19017797 PMID:19100238 GO_REF:0000107 MGI:3831067 MGI:3836228 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Dok1 docking protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
PR:P09581 (PMID:10585470)		 Ensembl
RGD		 PMID:10585470 GO_REF:0000107 NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465 		JBrowse link
macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:4943655|PMID:19413900)		 BHF-UCL
RGD		 PMID:19413900 GO_REF:0000024 MGI:4943655 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
negative regulation of appetite by leptin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbs2 Bardet-Biedl syndrome 2 involved_in ISO (MGI:3836843|PMID:19150989) RGD PMID:19150989 MGI:3836843 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 involved_in ISO (MGI:3836843|PMID:19150989) RGD PMID:19150989 MGI:3836843 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Lep leptin involved_in IDA
IBA		 PMID:11677594
GO_REF:0000033		 GO_Central PMID:11677594 GO_REF:0000033, RGD:10448951 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mkks MKKS centrosomal shuttling protein involved_in ISO (MGI:3836843|PMID:19150989) RGD PMID:19150989 MGI:3836843 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Mir101-2 microRNA 101-2 involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO
IEA		 (PMID:18645041)
GO_REF:0000107		 RGD
Ensembl		 PMID:18645041 GO_REF:0000107 NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Rnf113a1 ring finger protein 113A1 involved_in ISO (PMID:28978524) RGD PMID:28978524 NCBI chr  X:116,427,941...116,429,164
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:18829537) RGD PMID:18829537 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO (MGI:3510267|PMID:15337790) RGD PMID:15337790 MGI:3510267 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
negative regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180364 (PMID:12388746)		 Ensembl
RGD		 PMID:12388746 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21217760)		 Ensembl
RGD		 PMID:21217760 GO_REF:0000107 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) RGD PMID:23147407 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:30106099) RGD PMID:30106099 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of ISO (PMID:23729669) RGD PMID:23729669 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of ISO (PMID:23729669) RGD PMID:23729669 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Palm3 paralemmin 3 involved_in ISO
IBA		 (PMID:21187075)
GO_REF:0000033		 RGD
GO_Central		 PMID:21187075 GO_REF:0000033 NCBI chr19:24,121,984...24,126,079
Ensembl chr19:24,122,239...24,130,448 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO		 GO_REF:0000024
(MGI:2386427|PMID:11201744)		 UniProt
RGD		 PMID:11201744 GO_REF:0000024 MGI:2386427 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F IMP hepatocyte growth factor/Met signaling RGD PMID:16415345 RGD:1642742 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023 		JBrowse link
G Sigirr single Ig and TIR domain containing involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:2673012|PMID:12925853)		 HGNC-UCL
Ensembl
RGD		 PMID:12925853 GO_REF:0000024 GO_REF:0000107 MGI:2673012 NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269 		JBrowse link
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
PR:000045525 (PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rn interleukin 1 receptor antagonist involved_in ISO
IBA
IEA		 (PMID:2137200), (PMID:2139180)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:2137200 PMID:2139180 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mir21 microRNA 21 acts_upstream_of_or_within ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir27a microRNA 27a involved_in ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA		 (PMID:29395066)
GO_REF:0000033
(MGI:6120140|PMID:29395066)		 RGD
GO_Central		 PMID:29395066 GO_REF:0000033 MGI:6120140 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
negative regulation of interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Usp25 ubiquitin specific peptidase 25 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23042150)		 Ensembl
RGD		 PMID:23042150 GO_REF:0000107 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
negative regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:6706628|PMID:32424362)		 UniProt
RGD		 PMID:32424362 GO_REF:0000024 MGI:6706628 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
negative regulation of interleukin-2-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3691503|PMID:11909529)
(PMID:11909529)		 UniProt
Ensembl
RGD		 PMID:11909529 GO_REF:0000024 GO_REF:0000107 MGI:3691503 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:17210636)
GO_REF:0000107
(MGI:5493214|PMID:17210636)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17210636 GO_REF:0000024 GO_REF:0000107 MGI:5493214 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO (PMID:8353278) RGD PMID:8353278 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Mir125a microRNA 125a acts_upstream_of_or_within ISO UniProtKB:P05231 (PMID:30670152) RGD PMID:30670152 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir125b1 microRNA 125b-1 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:23389848) RGD PMID:23389848 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir98 microRNA 98 involved_in ISO UniProtKB:P05231 (PMID:26587789), (PMID:31886314) RGD PMID:26587789 PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mir99a microRNA 99a involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mirlet7a1 microRNA let-7a-1 involved_in ISO (PMID:19878981) RGD PMID:19878981 NCBI chr17:16,113,766...16,113,859
Ensembl chr17:16,113,768...16,113,867 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mirlet7c2 microRNA let7c-2 involved_in ISO (PMID:19878981) RGD PMID:19878981 NCBI chr 7:116,803,771...116,803,865
Ensembl chr 7:116,803,771...116,803,865 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:12359225)
GO_REF:0000107
(MGI:4941441|PMID:20484139)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12359225 PMID:20484139 GO_REF:0000024 GO_REF:0000107 MGI:4941441 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of Kit signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:16533754) RGD PMID:16533754 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO GO:1990782 (MGI:3041996|PMID:14612394) RGD PMID:14612394 MGI:3041996 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
negative regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3629372|PMID:16705167)		 UniProt
Ensembl
RGD		 PMID:16705167 GO_REF:0000024 GO_REF:0000107 MGI:3629372 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) RGD PMID:33097708 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:10604883)		 UniProt
RGD		 PMID:10604883 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:21571275)
GO_REF:0000107		 RGD
Ensembl		 PMID:21571275 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in ISO (PMID:25193116) RGD PMID:25193116 NCBI chr17:73,031,891...73,135,173
Ensembl chr17:73,035,045...73,135,337 		JBrowse link
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (PMID:22437732) RGD PMID:22437732 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351 		JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19781631) RGD PMID:19781631 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS		 (PMID:19657094)
GO_REF:0000024		 RGD
UniProt		 PMID:19657094 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:6148454|PMID:22424771) RGD PMID:22424771 MGI:6148454 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Hist2h2be histone cluster 2 H2B family member E involved_in ISO (PMID:11859126) RGD PMID:11859126 NCBI chr 2:183,780,583...183,783,030 JBrowse link
G Mir125b1 microRNA 125b-1 acts_upstream_of ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 acts_upstream_of ISO (PMID:26435691) RGD PMID:26435691 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir130a microRNA 130a acts_upstream_of ISO (PMID:26435691) RGD PMID:26435691 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir152 microRNA 152 involved_in ISO (PMID:24813629) RGD PMID:24813629 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5617337|PMID:24440909)		 Ensembl
RGD		 PMID:24440909 GO_REF:0000107 MGI:5617337 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (MGI:5707586|PMID:18972444)
GO_REF:0000107		 RGD
Ensembl		 PMID:18972444 GO_REF:0000107 MGI:5707586 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:24113711)
MGI:5441750 (PMID:23950925)		 RGD PMID:23950925 PMID:24113711 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (PMID:20054338) RGD PMID:20054338 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta acts_upstream_of ISO UniProtKB:P01375 (PMID:28159925) RGD PMID:28159925 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3530208|PMID:15696169)		 UniProt
Ensembl
RGD		 PMID:15696169 GO_REF:0000024 GO_REF:0000107 MGI:3530208 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 (PMID:18450452)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18450452 GO_REF:0000024 GO_REF:0000107 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:8710854) RGD PMID:8710854 NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (PMID:22437732) RGD PMID:22437732 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B acts_upstream_of_or_within ISO (PMID:29415886) RGD PMID:29415886 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Traip TRAF-interacting protein involved_in ISO (PMID:19151749) RGD PMID:19151749 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO
IEA		 (PMID:11865055)
GO_REF:0000107		 RGD
Ensembl		 PMID:11865055 GO_REF:0000107 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3828307 (PMID:19060901)		 Ensembl
RGD		 PMID:19060901 GO_REF:0000107 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:28724761) RGD PMID:28724761 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:37656786) RGD PMID:37656786 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO
IBA		 (PMID:20434986)
GO_REF:0000033
(MGI:4454346|PMID:20434986)		 RGD
GO_Central		 PMID:20434986 GO_REF:0000033 MGI:4454346 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:11909529)
GO_REF:0000107
(MGI:3691503|PMID:11909529), (MGI:5493216|PMID:12138178)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11909529 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:3691503 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29670289)
(MGI:5521417|PMID:23972988)		 RGD PMID:23972988 PMID:29670289 MGI:5521417 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Smim30 small integral membrane protein 30 involved_in ISO (PMID:37656786) RGD PMID:37656786 NCBI chr  X:34,443,180...34,443,365 JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:28165510)
(MGI:6508512|PMID:28165510)		 RGD PMID:28165510 MGI:6508512 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (PMID:18724932) RGD PMID:18724932 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO (MGI:6316470|PMID:30591559) RGD PMID:30591559 MGI:6316470 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (PMID:16709924)
GO_REF:0000107		 RGD
Ensembl		 PMID:16709924 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11679576) RGD PMID:11679576 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Otop1 otopetrin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5750846|PMID:24379350)		 UniProt
RGD		 PMID:24379350 GO_REF:0000024 MGI:5750846 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:21268089) RGD PMID:21268089 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in
NOT|involved_in		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:12138178)
GO_REF:0000107
(MGI:5493216|PMID:12138178)		 UniProt
RGD
Ensembl		 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
oncostatin-M-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 (PMID:8999038)
GO_REF:0000107		 RGD
Ensembl		 PMID:8999038 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Lifr LIF receptor subunit alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:8999038)		 Ensembl
RGD		 PMID:8999038 GO_REF:0000107 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Osm oncostatin M involved_in ISO (PMID:28972028), (PMID:8999038) RGD PMID:8999038 PMID:28972028 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Osmr oncostatin M receptor involved_in ISO
IEA		 (PMID:8999038)
GO_REF:0000107		 RGD
Ensembl		 PMID:8999038 GO_REF:0000107 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
positive regulation of C-C chemokine receptor CCR7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:11602640) RGD PMID:11602640 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 acts_upstream_of ISO (PMID:17178876) RGD PMID:17178876 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:17178876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
positive regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:4419085|PMID:12782713)
(PMID:12782713)		 BHF-UCL
GO_Central
RGD		 PMID:12782713 GO_REF:0000024 GO_REF:0000033 MGI:4419085 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS		 (PMID:18840707)
GO_REF:0000024		 RGD
UniProt		 PMID:18840707 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Il7 interleukin 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11418668)		 Ensembl
RGD		 PMID:11418668 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (PMID:22073305) RGD PMID:22073305 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070 (PMID:11894097) RGD PMID:11894097 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Trim44 tripartite motif-containing 44 involved_in ISO
IEA		 (PMID:23460740)
GO_REF:0000107		 RGD
Ensembl		 PMID:23460740 GO_REF:0000107 NCBI chr 3:88,593,619...88,729,085
Ensembl chr 3:88,592,719...88,729,188 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO
IBA		 (PMID:11418668)
GO_REF:0000033		 RGD
GO_Central		 PMID:11418668 GO_REF:0000033 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
positive regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r1 interleukin 1 receptor type 1 acts_upstream_of_or_within ISO PR:000045524 (PMID:23395675) RGD PMID:23395675 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
positive regulation of interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim32 tripartite motif-containing 32 acts_upstream_of_or_within ISO (PMID:20054338) RGD PMID:20054338 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
positive regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp4 caspase 4 involved_in ISO (PMID:33377178)
(MGI:6259277|PMID:30392956)		 RGD PMID:30392956 PMID:33377178 MGI:6259277 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5704237|PMID:26638072), (MGI:6259277|PMID:30392956), (MGI:6833928|PMID:34678144)
(PMID:33377178), (PMID:34161762)		 UniProt
Ensembl
RGD		 PMID:26638072 PMID:30392956 PMID:33377178 PMID:34161762 PMID:34678144 GO_REF:0000024 GO_REF:0000107 MGI:5704237 MGI:6259277 MGI:6833928 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:22685567)
(MGI:5488868|PMID:22685567)		 RGD PMID:22685567 MGI:5488868 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
positive regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(MGI:5660125|PMID:26124135)		 UniProt
RGD		 PMID:26124135 GO_REF:0000024 MGI:5660125 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
positive regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf4 C1q and TNF related 4 involved_in ISO (PMID:21658842) RGD PMID:21658842 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO
IEA		 (PMID:11060035)
GO_REF:0000107		 RGD
Ensembl		 PMID:11060035 GO_REF:0000107 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:31827280)
(MGI:6401044|PMID:31827281)		 RGD PMID:31827280 PMID:31827281 MGI:6401044 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
positive regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1 colony stimulating factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19100238)		 Ensembl
RGD		 PMID:19100238 GO_REF:0000107 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
positive regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule involved_in ISO
IEA		 (PMID:19665027)
GO_REF:0000107		 RGD
Ensembl		 PMID:19665027 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO (PMID:19665027) RGD PMID:19665027 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
positive regulation of prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor acts_upstream_of_or_within ISO (PMID:23071095) RGD PMID:23071095 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA		 (PMID:24813629)
GO_REF:0000107		 RGD
Ensembl		 PMID:24813629 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Casp1 caspase 1 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cpne1 copine 1 involved_in ISO
IBA
IEA		 (PMID:14674885)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14674885 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6201889|PMID:25049354)		 Ensembl
RGD		 PMID:25049354 PMID:25049354 GO_REF:0000107 MGI:6201889, RGD:13792525 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 (PMID:23453807)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6271183|PMID:30439713) RGD PMID:30439713 MGI:6271183 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (MGI:5616328|PMID:11374864) RGD PMID:11374864 MGI:5616328 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Trim32 tripartite motif-containing 32 acts_upstream_of_or_within ISO (PMID:20054338) RGD PMID:20054338 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:26707646) RGD PMID:26707646 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO (PMID:21109225) RGD PMID:21109225 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (MGI:5792628|PMID:27129230)
(PMID:24882218)		 RGD PMID:24882218 PMID:27129230 MGI:5792628 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (PMID:17618271) RGD PMID:17618271 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO (PMID:17618271) RGD PMID:17618271 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO (PMID:22745163) RGD PMID:22745163 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453 PMID:20451243 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:34160127) RGD PMID:34160127 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
IEA
ISS		 (PMID:28273161)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28273161 GO_REF:0000024 GO_REF:0000107 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:23910378)
GO_REF:0000107
(MGI:6827194|PMID:23910378)		 RGD
Ensembl		 PMID:23910378 GO_REF:0000107 MGI:6827194 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:5792628 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Trim41 tripartite motif-containing 41 involved_in ISO (PMID:29760876) RGD PMID:29760876 NCBI chr10:33,175,213...33,186,472
Ensembl chr10:33,175,213...33,186,694 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904)
(MGI:6119245|PMID:29426904)		 RGD PMID:29426904 MGI:6119245 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218)
(MGI:5645191|PMID:24882218)		 RGD PMID:24882218 MGI:5645191 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked involved_in ISO (PMID:31534008) RGD PMID:31534008 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Usp29 ubiquitin specific peptidase 29 involved_in ISO (MGI:6761183|PMID:32457395) RGD PMID:32457395 MGI:6761183 NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:19399181)
GO_REF:0000107		 RGD
Ensembl		 PMID:19399181 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(PMID:17618271)
GO_REF:0000033
GO_REF:0000118		 InterPro
RGD
GO_Central
TreeGrafter		 PMID:17618271 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (PMID:18641331) RGD PMID:18641331 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:16888103)
(MGI:3656111|PMID:16888103)		 RGD PMID:16888103 MGI:3656111 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:2176946|MGI:3511276 (PMID:18339625) RGD PMID:18339625 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403), (PMID:20639463) RGD PMID:20061403 PMID:20639463 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO
IBA		 (PMID:27796300)
GO_REF:0000033
(MGI:5905929|PMID:27796300)		 RGD
GO_Central		 PMID:27796300 GO_REF:0000033 MGI:5905929 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Txk TXK tyrosine kinase involved_in ISO (PMID:11859127) RGD PMID:11859127 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:23619365) RGD PMID:23619365 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prlr prolactin receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:23619365) RGD PMID:23619365 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule involved_in ISO
ISS		 (MGI:3614932|PMID:16390867) RGD PMID:16390867 PMID:16390867 MGI:3614932, RGD:8553244 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:10383454) RGD PMID:10383454 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in ISO (PMID:10383454) RGD PMID:10383454 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vrk2 VRK serine/threonine kinase 2 involved_in ISO (PMID:18286207) RGD PMID:18286207 NCBI chr14:100,313,771...100,434,520
Ensembl chr14:100,313,601...100,434,527 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6394181|PMID:31630209)		 UniProt
RGD		 PMID:31630209 GO_REF:0000024 MGI:6394181 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5912943|PMID:28701375)
(PMID:26997266), (PMID:27458237), (PMID:27591049)		 UniProt
RGD		 PMID:26997266 PMID:27458237 PMID:27591049 PMID:28701375 GO_REF:0000024 MGI:5912943 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:29415886) RGD PMID:29415886 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in ISO
IEA		 (PMID:15701637)
GO_REF:0000107		 RGD
Ensembl		 PMID:15701637 GO_REF:0000107 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 acts_upstream_of_or_within ISO MGI:1314884|MGI:1919216 (PMID:25220458) RGD PMID:25220458 NCBI chr15:7,493,531...7,503,758
Ensembl chr15:7,493,531...7,503,854 		JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 acts_upstream_of_or_within ISO MGI:1314884|MGI:1916971 (PMID:25220458) RGD PMID:25220458 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO
IBA		 (PMID:26997266)
GO_REF:0000033
(MGI:5804663|PMID:27523608), (MGI:6192867|PMID:29950720)		 RGD
GO_Central		 PMID:26997266 PMID:27523608 PMID:29950720 GO_REF:0000033 MGI:5804663 MGI:6192867 NCBI chr 2:78,290,437...78,316,633
Ensembl chr 2:78,290,959...78,316,422 		JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17442941)		 Ensembl
RGD		 PMID:17442941 GO_REF:0000107 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sharpin SHANK-associated RH domain interactor involved_in ISO
ISS		 (PMID:21455173)
GO_REF:0000024
(MGI:4947438|PMID:21455180), (MGI:4947439|PMID:21455173)		 RGD
UniProt		 PMID:21455173 PMID:21455180 GO_REF:0000024 MGI:4947438 MGI:4947439 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
G Spata2 spermatogenesis associated 2 involved_in ISO
IBA
IEA
ISS		 (PMID:27307491), (PMID:27458237), (PMID:27545878), (PMID:27591049)
GO_REF:0000033
GO_REF:0000118
(MGI:5912943|PMID:28701375)
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
UniProt		 PMID:27307491 PMID:27458237 PMID:27545878 PMID:27591049 PMID:28701375 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5912943 NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
ISS
IMP		 (PMID:20577214)
GO_REF:0000107
GO_REF:0000024
PMID:28284343		 RGD
Ensembl
UniProt		 PMID:20577214 PMID:28284343 GO_REF:0000024 GO_REF:0000107, RGD:14397556 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19151749)
GO_REF:0000107		 RGD
Ensembl		 PMID:19151749 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A acts_upstream_of_or_within ISO MGI:1916971|MGI:1919216 (PMID:25220458) RGD PMID:25220458 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16280321)
GO_REF:0000107		 RGD
Ensembl		 PMID:16280321 GO_REF:0000107 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16280321)
GO_REF:0000107		 RGD
Ensembl		 PMID:16280321 GO_REF:0000107 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
thrombopoietin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cib1 calcium and integrin binding 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5314162|PMID:22128142)		 UniProt
Ensembl
RGD		 PMID:22128142 GO_REF:0000024 GO_REF:0000107 MGI:5314162 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor involved_in ISO
IBA		 (MGI:6158801|PMID:25468569)
GO_REF:0000033		 RGD
GO_Central		 PMID:25468569 GO_REF:0000033 MGI:6158801 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797 		JBrowse link
G Rbm15 RNA binding motif protein 15 involved_in ISO (MGI:6158801|PMID:25468569) RGD PMID:25468569 MGI:6158801 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 acts_upstream_of_or_within_negative_effect
acts_upstream_of_negative_effect
involved_in		 ISO (PMID:20404132)
UniProtKB:P35951 (MGI:5905608|PMID:27430239)
(MGI:3510267|PMID:15337790)		 RGD PMID:15337790 PMID:20404132 PMID:27430239 MGI:3510267 MGI:5905608 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Thpo thrombopoietin involved_in ISO
IBA
IEA
ISS		 (PMID:15337790)
GO_REF:0000033
GO_REF:0000107
(MGI:5314162|PMID:22128142)
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:15337790 PMID:22128142 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5314162 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Thpol1 thrombopoietin like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 involved_in ISO
IEA		 (PMID:25411248)
GO_REF:0000107		 RGD
Ensembl		 PMID:25411248 GO_REF:0000107 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Aim2 absent in melanoma 2 involved_in ISO (PMID:16432157) RGD PMID:16432157 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Card14 caspase recruitment domain family, member 14 involved_in ISO (PMID:21302310) RGD PMID:21302310 NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905 		JBrowse link
G Cd70 Cd70 molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in IBA
ISO		 GO_REF:0000033
(PMID:12656673)		 GO_Central
RGD		 PMID:12656673 GO_REF:0000033 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Commd7 COMM domain containing 7 involved_in ISO
IBA		 (PMID:15799966)
GO_REF:0000033		 RGD
GO_Central		 PMID:15799966 GO_REF:0000033 NCBI chr 3:142,099,566...142,114,348
Ensembl chr 3:142,099,251...142,114,317 		JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:17187778) RGD PMID:17187778 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Fas Fas cell surface death receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Foxo3 forkhead box O3 involved_in ISO (PMID:15084260) RGD PMID:15084260 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:12656673), (PMID:15084260), (PMID:25816133)
GO_REF:0000118
GO_REF:0000033
(MGI:5693235|PMID:15084260)		 Ensembl
RGD
TreeGrafter
GO_Central		 PMID:12656673 PMID:15084260 PMID:25816133 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5693235 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Ilk integrin-linked kinase involved_in ISO
IEA		 (PMID:21343177)
GO_REF:0000107		 RGD
Ensembl		 PMID:21343177 GO_REF:0000107 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:8609418) RGD PMID:8609418 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within ISO MGI:96705 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within ISO MGI:2178042|MGI:96692 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 involved_in ISO (PMID:21343177) RGD PMID:21343177 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:26949937) RGD PMID:26949937 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:25038658) RGD PMID:25038658 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor involved_in ISO MGI:2386083 (PMID:14985352) RGD PMID:14985352 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627 		JBrowse link
G Plvap plasmalemma vesicle associated protein involved_in ISO (PMID:19420356) RGD PMID:19420356 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO (PMID:8670418) RGD PMID:8670418 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:12656673) RGD PMID:12656673 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO UniProtKB:P01375 (PMID:21343177), (PMID:23878390), (PMID:25411248), (PMID:28159925) RGD PMID:21343177 PMID:23878390 PMID:25411248 PMID:28159925 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rraga Ras-related GTP binding A involved_in ISO
IEA		 (PMID:8995684)
GO_REF:0000107		 RGD
Ensembl		 PMID:8995684 GO_REF:0000107 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor involved_in ISO
IEA		 (PMID:18676404)
GO_REF:0000107		 RGD
Ensembl		 PMID:18676404 GO_REF:0000107 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:10848577) RGD PMID:10848577 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISO PR:P39429 (PMID:11798190) RGD PMID:11798190 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked acts_upstream_of_or_within_positive_effect ISO (PMID:21343177) RGD PMID:21343177 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
IMP		 (PMID:10748004), (PMID:28159925), (PMID:31824476)
(PMID:10411298), (PMID:14985352)
(PMID:3898078)
GO_REF:0000033
GO_REF:0000118
PMID:12729461		 RGD
GO_Central
TreeGrafter		 PMID:3898078 PMID:10411298 PMID:10748004 PMID:14985352 PMID:28159925 More... GO_REF:0000033 GO_REF:0000118, RGD:13673777 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO
IBA		 (MGI:4413614|PMID:19940926)
GO_REF:0000033
(PMID:18606301)		 RGD
GO_Central		 PMID:18606301 PMID:19940926 GO_REF:0000033 MGI:4413614 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517 		JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:166,618,461...166,622,353
Ensembl chr 5:166,618,969...166,622,353 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA		 UniProtKB:P01375 (PMID:14985352)
MGI:1861040 (MGI:2152007|PMID:11588035)
GO_REF:0000107
GO_REF:0000002
(PMID:25816133)		 RGD
Ensembl
InterPro		 PMID:11588035 PMID:14985352 PMID:25816133 PMID:20967881 GO_REF:0000002 GO_REF:0000107 MGI:2152007, RGD:5130945 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
UniProtKB:P43488 (MGI:2683815|PMID:14635034)		 GOC
RGD		 PMID:14635034 GO_REF:0000108 MGI:2683815 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 ISO
IEA		 UniProtKB:O35305 (MGI:4413614|PMID:19940926)
(PMID:17442941), (PMID:18269914), (PMID:22437732)
(PMID:18606301)
GO_REF:0000107		 RGD
Ensembl		 PMID:17442941 PMID:18269914 PMID:18606301 PMID:19940926 PMID:22437732 GO_REF:0000107 MGI:4413614 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf13b TNF superfamily member 13b involved_in ISO MGI:2143599 (PMID:18624351) RGD PMID:18624351 NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO
IBA		 (MGI:5306317|PMID:14521928)
GO_REF:0000033		 RGD
GO_Central		 PMID:14521928 GO_REF:0000033 MGI:5306317 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 UniProtKB:P01375 (PMID:22499991)
GO_REF:0000107		 RGD
Ensembl		 PMID:22499991 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in ISO (PMID:7758105) RGD PMID:7758105 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IMP
ISO
IBA		 (PMID:8710854)
GO_REF:0000033
(PMID:11907583)		 RGD
GO_Central		 PMID:8710854 PMID:11907583 PMID:10713108 PMID:20967881 GO_REF:0000033, RGD:2298798, RGD:5130945 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO
IBA		 (PMID:20185819)
GO_REF:0000033
(MGI:3722053|PMID:17015635)		 RGD
GO_Central		 PMID:17015635 PMID:20185819 GO_REF:0000033 MGI:3722053 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:1344376 (PMID:18624351) RGD PMID:18624351 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Txndc17 thioredoxin domain containing 17 involved_in ISO (PMID:14607844) RGD PMID:14607844 NCBI chr10:56,832,749...56,835,721 JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:28990932) RGD PMID:28990932 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068074 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:59,549,152...59,549,829 JBrowse link
G ENSRNOG00000070481 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:30,960,845...30,961,834 JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (PMID:31127039) RGD PMID:31127039 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:27777077) RGD PMID:27777077 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 acts_upstream_of_or_within ISO MGI:3663677 (PMID:28031478) RGD PMID:28031478 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Ifitm2-ps2 interferon induced transmembrane protein 2, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:20064371)		 GO_Central
RGD		 PMID:20064371 GO_REF:0000033 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Ifitm3-ps1 interferon induced transmembrane protein3, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688 		JBrowse link
G Ifitm6 interferon induced transmembrane protein 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386 		JBrowse link
G Ifitm7 interferon induced transmembrane protein 7 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in ISO (MGI:5583923|PMID:24784232) RGD PMID:24784232 MGI:5583923 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 involved_in ISO
IBA		 (MGI:5562515|PMID:23872679), (MGI:5705226|PMID:14532120), (MGI:5792628|PMID:27129230)
GO_REF:0000033
(PMID:21854986), (PMID:7665574)		 RGD
GO_Central		 PMID:7665574 PMID:14532120 PMID:21854986 PMID:23872679 PMID:27129230 GO_REF:0000033 MGI:5562515 MGI:5705226 MGI:5792628 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 involved_in ISO
IBA		 (PMID:21854986), (PMID:26424569), (PMID:7665574)
GO_REF:0000033		 RGD
GO_Central		 PMID:7665574 PMID:21854986 PMID:26424569 GO_REF:0000033 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (MGI:5792628|PMID:27129230)
(PMID:18035482), (PMID:33581076)		 RGD PMID:18035482 PMID:27129230 PMID:33581076 MGI:5792628 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:5792628 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:5792628 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:7532278), (PMID:8232552) RGD PMID:7532278 PMID:8232552 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:28640813) RGD PMID:28640813 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6094812|PMID:29117179)		 UniProt
RGD		 PMID:29117179 GO_REF:0000024 MGI:6094812 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO
IBA		 (PMID:23386060)
GO_REF:0000033
(MGI:5493216|PMID:12138178), (MGI:5619426|PMID:24598055)		 RGD
GO_Central		 PMID:12138178 PMID:23386060 PMID:24598055 GO_REF:0000033 MGI:5493216 MGI:5619426 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO
IBA		 (PMID:23391734), (PMID:31836668), (PMID:32092142)
GO_REF:0000033
(MGI:5619426|PMID:24598055), (MGI:6508512|PMID:28165510)		 RGD
GO_Central		 PMID:23391734 PMID:24598055 PMID:28165510 PMID:31836668 PMID:32092142 GO_REF:0000033 MGI:5619426 MGI:6508512 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (PMID:28351661) RGD PMID:28351661 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Trim65 tripartite motif-containing 65 acts_upstream_of_or_within ISO MGI:6356825 (PMID:28031478) RGD PMID:28031478 NCBI chr10:101,357,937...101,364,036
Ensembl chr10:101,357,937...101,364,971 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:8232552) RGD PMID:8232552 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of ISO MGI:2447193 (PMID:18641331) RGD PMID:18641331 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Ifng interferon gamma involved_in ISO (MGI:5490676|PMID:23629966)
(PMID:16914093), (PMID:22504299), (PMID:23629966)		 RGD PMID:16914093 PMID:22504299 PMID:23629966 MGI:5490676 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO (PMID:28883123) RGD PMID:28883123 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ifngr2 interferon gamma receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5317515|PMID:21909274)		 UniProt
RGD		 PMID:21909274 GO_REF:0000024 MGI:5317515 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:8232552) RGD PMID:8232552 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 involved_in IDA PMID:11536325 BHF-UCL PMID:11536325 RGD:8553830 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:21268089), (PMID:26479788)
(MGI:5493216|PMID:12138178)		 RGD PMID:12138178 PMID:21268089 PMID:26479788 MGI:5493216 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (MGI:5490676|PMID:23629966)
GO_REF:0000107		 RGD
Ensembl		 PMID:23629966 GO_REF:0000107 MGI:5490676 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:8232552) RGD PMID:8232552 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
type III interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:16914093) RGD PMID:16914093 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO (PMID:20015550) RGD PMID:20015550 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ifngr2 interferon gamma receptor 2 involved_in ISO (PMID:20015550) RGD PMID:20015550 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        cell surface receptor signaling pathway 2886
          cytokine-mediated signaling pathway 492
            Kit signaling pathway + 4
            adiponectin-activated signaling pathway 7
            chemokine-mediated signaling pathway + 82
            ciliary neurotrophic factor-mediated signaling pathway 5
            erythropoietin-mediated signaling pathway 3
            granulocyte colony-stimulating factor signaling pathway 5
            granulocyte-macrophage colony-stimulating factor signaling pathway 4
            interferon-mediated signaling pathway + 83
            interleukin-1-mediated signaling pathway + 31
            interleukin-10-mediated signaling pathway 7
            interleukin-11-mediated signaling pathway 6
            interleukin-12-mediated signaling pathway 8
            interleukin-13-mediated signaling pathway 3
            interleukin-15-mediated signaling pathway 11
            interleukin-17-mediated signaling pathway + 12
            interleukin-17A-mediated signaling pathway 6
            interleukin-18-mediated signaling pathway + 10
            interleukin-19-mediated signaling pathway 0
            interleukin-2-mediated signaling pathway + 9
            interleukin-20-mediated signaling pathway 0
            interleukin-21-mediated signaling pathway 0
            interleukin-22-mediated signaling pathway 3
            interleukin-23-mediated signaling pathway 3
            interleukin-27-mediated signaling pathway + 7
            interleukin-3-mediated signaling pathway 7
            interleukin-32-mediated signaling pathway 0
            interleukin-33-mediated signaling pathway 8
            interleukin-34-mediated signaling pathway 1
            interleukin-35-mediated signaling pathway + 0
            interleukin-4-mediated signaling pathway + 9
            interleukin-5-mediated signaling pathway 6
            interleukin-6-mediated signaling pathway + 28
            interleukin-7-mediated signaling pathway 4
            interleukin-8-mediated signaling pathway 2
            interleukin-9-mediated signaling pathway 7
            leptin-mediated signaling pathway + 12
            macrophage colony-stimulating factor signaling pathway + 6
            macrophage migration inhibitory factor signaling pathway + 3
            negative regulation of cytokine-mediated signaling pathway + 93
            oncostatin-M-mediated signaling pathway 4
            positive regulation of cytokine-mediated signaling pathway + 59
            prolactin signaling pathway + 4
            regulation of cytokine-mediated signaling pathway + 164
            tumor necrosis factor-mediated signaling pathway + 103
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of cellular process 12748
          signal transduction 7209
            cell surface receptor signaling pathway 2886
              cytokine-mediated signaling pathway 492
                Kit signaling pathway + 4
                adiponectin-activated signaling pathway 7
                chemokine-mediated signaling pathway + 82
                ciliary neurotrophic factor-mediated signaling pathway 5
                erythropoietin-mediated signaling pathway 3
                granulocyte colony-stimulating factor signaling pathway 5
                granulocyte-macrophage colony-stimulating factor signaling pathway 4
                interferon-mediated signaling pathway + 83
                interleukin-1-mediated signaling pathway + 31
                interleukin-10-mediated signaling pathway 7
                interleukin-11-mediated signaling pathway 6
                interleukin-12-mediated signaling pathway 8
                interleukin-13-mediated signaling pathway 3
                interleukin-15-mediated signaling pathway 11
                interleukin-17-mediated signaling pathway + 12
                interleukin-17A-mediated signaling pathway 6
                interleukin-18-mediated signaling pathway + 10
                interleukin-19-mediated signaling pathway 0
                interleukin-2-mediated signaling pathway + 9
                interleukin-20-mediated signaling pathway 0
                interleukin-21-mediated signaling pathway 0
                interleukin-22-mediated signaling pathway 3
                interleukin-23-mediated signaling pathway 3
                interleukin-27-mediated signaling pathway + 7
                interleukin-3-mediated signaling pathway 7
                interleukin-32-mediated signaling pathway 0
                interleukin-33-mediated signaling pathway 8
                interleukin-34-mediated signaling pathway 1
                interleukin-35-mediated signaling pathway + 0
                interleukin-4-mediated signaling pathway + 9
                interleukin-5-mediated signaling pathway 6
                interleukin-6-mediated signaling pathway + 28
                interleukin-7-mediated signaling pathway 4
                interleukin-8-mediated signaling pathway 2
                interleukin-9-mediated signaling pathway 7
                leptin-mediated signaling pathway + 12
                macrophage colony-stimulating factor signaling pathway + 6
                macrophage migration inhibitory factor signaling pathway + 3
                negative regulation of cytokine-mediated signaling pathway + 93
                oncostatin-M-mediated signaling pathway 4
                positive regulation of cytokine-mediated signaling pathway + 59
                prolactin signaling pathway + 4
                regulation of cytokine-mediated signaling pathway + 164
                tumor necrosis factor-mediated signaling pathway + 103
paths to the root