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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphate metabolic process
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Accession:GO:0019220 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
Synonyms:exact_synonym: regulation of phosphate metabolism


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activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:9314843 RGD:6478796 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G GHR growth hormone receptor involved_in ISO PMID:8063815 RGD
BHF-UCL
PMID:8063815 PMID:11244571 RGD:1624962 RGD:8553732 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278
JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (MGI:63384|PMID:8378315) MGI PMID:8378315 MGI:63384 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G IL4 interleukin 4 involved_in ISO (PMID:12574355) ARUK-UCL PMID:12574355 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G JAK2 Janus kinase 2 involved_in ISO (MGI:4457458|PMID:20304997) UniProt PMID:20304997 MGI:4457458 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G PIBF1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) UniProt PMID:16393965 NCBI chr13:54,011,239...54,247,952
Ensembl chr13:72,788,608...73,022,473
JBrowse link
G PRLR prolactin receptor involved_in ISO (PMID:10585417) UniProt PMID:10585417 NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in ISO (PMID:8670418) RGD
UniProt
PMID:8670418 PMID:11818507 RGD:633057 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
activation of JNKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO (MGI:3654809|PMID:16319174) MGI PMID:16319174 MGI:3654809 NCBI chr10:44,703,720...44,784,948 JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:17064355 RGD:2298577 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737
JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 involved_in ISO (MGI:5810221|PMID:27511108) ARUK-UCL PMID:27511108 MGI:5810221 NCBI chr12:35,253,814...35,273,739
Ensembl chr12:36,038,634...36,058,200
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (MGI:5810221|PMID:27511108) ARUK-UCL PMID:27511108 MGI:5810221 NCBI chr 3:182,319,405...182,517,655
Ensembl chr 3:190,798,694...190,993,633
JBrowse link
G TNIK TRAF2 and NCK interacting kinase involved_in ISO (PMID:15342639)
(PMID:10521462)
UniProt PMID:10521462 PMID:15342639 NCBI chr 3:168,067,839...168,466,290
Ensembl chr 3:176,255,547...176,650,795
JBrowse link
activation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (MGI:5284790|PMID:16027136) BHF-UCL PMID:16027136 MGI:5284790 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108
JBrowse link
G CD40LG CD40 ligand involved_in ISO (PMID:15067037) UniProt PMID:15067037 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:12813029) BHF-UCL PMID:12813029 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO (MGI:3654809|PMID:16319174) MGI PMID:16319174 MGI:3654809 NCBI chr10:44,703,720...44,784,948 JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:10650002)
(MGI:3777353|PMID:10650002)
ParkinsonsUK-UCL PMID:10650002 MGI:3777353 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (MGI:3777353|PMID:10650002) ParkinsonsUK-UCL PMID:10650002 MGI:3777353 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258
JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 ISO RGD PMID:9668039 RGD:1299389 NCBI chr12:53,574,573...53,822,971
Ensembl chr12:56,181,565...56,421,810
JBrowse link
G LOC100995326 serotransferrin involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:12524169 PMID:17064355 RGD:2298577 RGD:2298708 NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within
involved_in
ISO (MGI:3032484|PMID:14967141)
(MGI:1890011|PMID:10523642)
MGI
BHF-UCL
PMID:10523642 PMID:14967141 MGI:1890011 MGI:3032484 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:15258589) UniProt PMID:15258589 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737
JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 involved_in ISO (MGI:5810221|PMID:27511108) ARUK-UCL PMID:27511108 MGI:5810221 NCBI chr12:35,253,814...35,273,739
Ensembl chr12:36,038,634...36,058,200
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (MGI:5810221|PMID:27511108) ARUK-UCL PMID:27511108 MGI:5810221 NCBI chr 3:182,319,405...182,517,655
Ensembl chr 3:190,798,694...190,993,633
JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) UniProt PMID:11836244 NCBI chr2B:60,362,635...60,555,445
Ensembl chr2B:177,818,344...178,010,556
JBrowse link
G MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 involved_in ISO (PMID:8824585) UniProt PMID:8824585 NCBI chr19:35,685,526...35,714,300
Ensembl chr19:44,256,655...44,285,969
JBrowse link
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) UniProt PMID:17584736 NCBI chr11:60,142,445...60,158,728
Ensembl chr11:63,486,827...63,499,746
JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 involved_in
acts_upstream_of_or_within
ISO PMID:21076496
(MGI:3575843|PMID:15767678)
UniProt
MGI
PMID:15767678 PMID:21076496 MGI:3575843 RGD:13673827 NCBI chr16:327,995...392,691
Ensembl chr16:1,759,171...1,821,246
JBrowse link
G MDFI MyoD family inhibitor involved_in ISO (MGI:4441137|PMID:12192039) UniProt PMID:12192039 MGI:4441137 NCBI chr 6:41,222,123...41,239,474
Ensembl chr 6:42,527,805...42,545,030
JBrowse link
G MDFIC MyoD family inhibitor domain containing involved_in ISO (PMID:12192039) UniProt PMID:12192039 NCBI chr 7:106,886,481...106,983,546
Ensembl chr 7:119,584,817...119,678,614
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) UniProt PMID:18591963 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (MGI:5616322|PMID:15465829) ParkinsonsUK-UCL PMID:15465829 MGI:5616322 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G SPAG9 sperm associated antigen 9 acts_upstream_of_or_within ISO (MGI:4835955|PMID:12391307) MGI PMID:12391307 MGI:4835955 NCBI chr17:45,053,292...45,211,488
Ensembl chr17:49,924,650...50,081,918
JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101
JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr13:23,750,835...23,784,740 JBrowse link
G WNT5A Wnt family member 5A involved_in ISO (PMID:20032469)
(PMID:20034610)
BHF-UCL PMID:20032469 PMID:20034610 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
G WNT7B Wnt family member 7B ISO RGD PMID:18177422 RGD:2292645 Ensembl chr22:44,988,647...45,044,841 JBrowse link
activation of MAPK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:28283184) CACAO PMID:28283184 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G APP amyloid beta precursor protein involved_in ISO PMID:11404397 ARUK-UCL PMID:11404397 RGD:12790656 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G AVPI1 arginine vasopressin induced 1 acts_upstream_of_or_within ISO (MGI:3036216|PMID:12356727) MGI PMID:12356727 MGI:3036216 NCBI chr10:94,294,365...94,303,970
Ensembl chr10:97,789,444...97,798,935
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in ISO (PMID:17202865), (PMID:22540193) AgBase PMID:17202865 PMID:22540193 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G C1QTNF2 C1q and TNF related 2 acts_upstream_of_or_within ISO (MGI:3055459|PMID:15231994) MGI PMID:15231994 MGI:3055459 NCBI chr 5:155,738,893...155,761,650
Ensembl chr 5:162,433,415...162,456,123
JBrowse link
G CD74 CD74 molecule ISO RGD PMID:12782713 RGD:728220 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334
JBrowse link
G CD81 CD81 molecule involved_in ISO (PMID:14676841) UniProt PMID:14676841 NCBI chr11:2,400,503...2,421,132
Ensembl chr11:2,437,991...2,449,308
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO (PMID:10771023) UniProt PMID:10771023 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:3847828|PMID:19307307) MGI PMID:19307307 MGI:3847828 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858
JBrowse link
G CXCL17 C-X-C motif chemokine ligand 17 involved_in ISO (PMID:23115081) UniProt PMID:23115081 NCBI chr19:39,315,929...39,331,651
Ensembl chr19:47,908,179...47,922,120
JBrowse link
G DRD4 dopamine receptor D4 involved_in ISO (PMID:15755724), (PMID:9843378) BHF-UCL PMID:9843378 PMID:15755724 NCBI chr11:640,401...646,775 JBrowse link
G EGF epidermal growth factor acts_upstream_of_or_within ISO (MGI:85697|PMID:9030684) MGI PMID:9030684 MGI:85697 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G EPGN epithelial mitogen involved_in ISO (MGI:1934957|PMID:11278323) HGNC-UCL PMID:11278323 MGI:1934957 NCBI chr 4:49,875,419...49,884,234 JBrowse link
G ERP29 endoplasmic reticulum protein 29 involved_in ISO (PMID:22064321) ParkinsonsUK-UCL PMID:22064321 NCBI chr12:109,610,692...109,620,390
Ensembl chr12:113,004,125...113,013,674
JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in ISO (PMID:24506284) AgBase PMID:24506284 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISO (PMID:18441324) UniProt PMID:18441324 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in ISO (PMID:14975937) UniProt PMID:14975937 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO (MGI:3580203|PMID:15870281)
(MGI:3513737|PMID:15569927)
(MGI:3772963|PMID:18184727)
MGI PMID:15569927 PMID:15870281 PMID:18184727 MGI:3513737 MGI:3580203 MGI:3772963 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293
JBrowse link
G GAB1 GRB2 associated binding protein 1 acts_upstream_of_or_within ISO (MGI:2664443|PMID:12808090) MGI PMID:12808090 MGI:2664443 NCBI chr 4:135,697,939...135,834,755
Ensembl chr 4:146,996,936...147,133,672
JBrowse link
G GDF15 growth differentiation factor 15 involved_in ISO (PMID:28953886)
(MGI:6101250|PMID:28953886)
UniProt PMID:28953886 MGI:6101250 NCBI chr19:17,864,840...17,867,883
Ensembl chr19:18,835,216...18,838,470
JBrowse link
G GFRAL GDNF family receptor alpha like involved_in ISO (PMID:28953886)
(MGI:6101250|PMID:28953886)
UniProt PMID:28953886 MGI:6101250 NCBI chr 6:54,878,072...54,946,716
Ensembl chr 6:56,512,880...56,581,527
JBrowse link
G GHR growth hormone receptor involved_in ISO PMID:8063815 BHF-UCL PMID:8063815 RGD:8553732 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278
JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in ISO (PMID:15350694) UniProt PMID:15350694 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723
JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (MGI:5707553|PMID:26375174) MGI PMID:26375174 MGI:5707553 NCBI chr2B:27,429,851...27,431,292 JBrowse link
G GRM1 glutamate metabotropic receptor 1 involved_in ISO (MGI:1934687|PMID:11356865) UniProt PMID:11356865 MGI:1934687 NCBI chr 6:143,819,364...144,231,304
Ensembl chr 6:148,537,036...148,947,047
JBrowse link
G GRM4 glutamate metabotropic receptor 4 involved_in ISO (PMID:15102938) UniProt PMID:15102938 NCBI chr 6:33,592,030...33,718,712
Ensembl chr 6:34,696,058...34,830,868
JBrowse link
G HGF hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) MGI PMID:15314156 MGI:3054501 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:22351760) UniProt PMID:22351760 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 involved_in ISO (PMID:24003225) UniProt PMID:24003225 NCBI chr12:35,654,172...35,659,115
Ensembl chr12:36,435,221...36,440,132
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (MGI:5291883|PMID:21822257) MGI PMID:21822257 MGI:5291883 NCBI chr 1:182,070,565...182,096,797
Ensembl chr 1:186,351,807...186,377,971
JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:10748004) BHF-UCL PMID:10748004 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G INAVA innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:176,491,264...176,514,719
Ensembl chr 1:180,794,646...180,818,853
JBrowse link
G INSR insulin receptor involved_in ISO (PMID:17001305) BHF-UCL PMID:17001305 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) MGI PMID:18604197 MGI:3835718 NCBI chr 1:131,869,002...131,916,554
Ensembl chr 1:135,695,602...135,740,564
JBrowse link
G ITGA1 integrin subunit alpha 1 ISO hippocampal neurons in response to beta-amyloid RGD PMID:14991844 RGD:2302385 NCBI chr 5:61,073,507...61,247,565
Ensembl chr 5:62,692,673...62,865,769
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:21640708) UniProt PMID:21640708 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473
JBrowse link
G LOC100978169 mucin-20 acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) MGI PMID:15314156 MGI:3054501
G LPAR1 lysophosphatidic acid receptor 1 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) MGI PMID:15755723 MGI:3584233 NCBI chr 9:82,013,960...82,179,227
Ensembl chr 9:110,179,600...110,279,038
JBrowse link
G LPAR2 lysophosphatidic acid receptor 2 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) MGI PMID:15755723 MGI:3584233 NCBI chr19:19,060,927...19,065,792
Ensembl chr19:20,057,179...20,061,260
JBrowse link
G LPAR3 lysophosphatidic acid receptor 3 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) MGI PMID:15755723 MGI:3584233 NCBI chr 1:117,359,661...117,441,297
Ensembl chr 1:86,222,008...86,274,228
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in ISO (PMID:21857923) ParkinsonsUK-UCL PMID:21857923 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G MADD MAP kinase activating death domain involved_in ISO (PMID:9115275)
(MGI:3700423|PMID:14735464)
UniProt PMID:9115275 PMID:14735464 MGI:3700423 NCBI chr11:47,216,006...47,276,422
Ensembl chr11:47,773,733...47,828,360
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 acts_upstream_of_or_within
involved_in
ISO (MGI:3579196|PMID:15896720)
(PMID:10644344)
RGD
MGI
AgBase
PMID:7935430 PMID:10644344 PMID:15896720 MGI:3579196 RGD:2293305 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161
JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 involved_in ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr15:46,493,139...46,760,271
Ensembl chr15:64,761,394...65,029,655
JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 involved_in
acts_upstream_of_or_within
ISO (PMID:8663524), (PMID:9218798)
(MGI:2152033|PMID:11593045)
(MGI:3032469|PMID:14744933), (MGI:3575843|PMID:15767678)
UniProt
MGI
PMID:8663524 PMID:9218798 PMID:11593045 PMID:14744933 PMID:15767678 MGI:2152033 MGI:3032469 MGI:3575843 NCBI chr17:63,342,720...63,483,926
Ensembl chr17:68,730,011...68,870,454
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:15258589) UniProt PMID:15258589 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 acts_upstream_of_or_within ISO (MGI:3575843|PMID:15767678) MGI PMID:15767678 MGI:3575843 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:9079627) UniProt PMID:9079627 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) MGI PMID:15314156 MGI:3054501 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G MOS MOS proto-oncogene, serine/threonine kinase involved_in ISO (MGI:80462|PMID:8631259), (MGI:81559|PMID:8692939) UniProt PMID:8631259 PMID:8692939 MGI:80462 MGI:81559 NCBI chr 8:52,559,066...52,560,362
Ensembl chr 8:49,930,077...49,931,117
JBrowse link
G NRG1 neuregulin 1 involved_in ISO (PMID:20682778) UniProt PMID:20682778 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G NTF3 neurotrophin 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3700006|PMID:17306762) MGI PMID:17306762 MGI:3700006 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PHB2 prohibitin 2 NOT|involved_in ISO (PMID:24003225) UniProt PMID:24003225 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G PLA2G1B phospholipase A2 group IB involved_in ISO (PMID:15528384), (PMID:16005851) BHF-UCL PMID:15528384 PMID:16005851 NCBI chr12:117,896,729...117,900,946
Ensembl chr12:121,270,082...121,275,740
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in ISO (PMID:11022047) UniProt PMID:11022047 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:15130913) UniProt PMID:15130913 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within ISO (MGI:3758374|PMID:17325201) MGI PMID:17325201 MGI:3758374 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 acts_upstream_of_or_within ISO (MGI:2679752|PMID:12937170)
(MGI:3047525|PMID:15273746)
MGI PMID:12937170 PMID:15273746 MGI:2679752 MGI:3047525 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:1095647 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G PXN paxillin acts_upstream_of_or_within ISO (MGI:2680875|PMID:14636584) MGI PMID:14636584 MGI:2680875 NCBI chr12:117,785,614...117,840,816
Ensembl chr12:121,160,295...121,176,667
JBrowse link
G RET ret proto-oncogene involved_in ISO (PMID:28953886) UniProt PMID:28953886 NCBI chr10:40,050,396...40,103,629
Ensembl chr10:43,249,468...43,284,331
JBrowse link
G SAA1 serum amyloid A1 involved_in ISO (PMID:22532826) CACAO PMID:22532826 NCBI chr11:18,301,367...18,305,137
Ensembl chr11:17,986,725...17,990,414
JBrowse link
G SHC1 SHC adaptor protein 1 involved_in ISO (PMID:20624904)
(PMID:14676841)
RGD
CAFA
UniProt
PMID:14676841 PMID:15262993 PMID:20624904 RGD:1580336 NCBI chr 1:130,310,778...130,323,001
Ensembl chr 1:133,920,532...133,929,008
JBrowse link
G SPAG9 sperm associated antigen 9 acts_upstream_of_or_within ISO (MGI:3575843|PMID:15767678) MGI PMID:15767678 MGI:3575843 NCBI chr17:45,053,292...45,211,488
Ensembl chr17:49,924,650...50,081,918
JBrowse link
G STK39 serine/threonine kinase 39 involved_in ISO PMID:10980603
(PMID:10980603)
UniProt PMID:10980603 RGD:727300 NCBI chr2B:55,204,203...55,501,033
Ensembl chr2B:172,674,514...172,970,063
JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133)
(MGI:79455|PMID:8626447)
MGI PMID:8626447 PMID:9000133 MGI:79455 MGI:85068 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101
JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 involved_in ISO (PMID:15327770), (PMID:22158122) UniProt PMID:15327770 PMID:22158122 NCBI chr 6:147,138,553...147,231,559
Ensembl chr 6:151,868,513...151,936,841
JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 involved_in ISO (PMID:15327770), (PMID:22158122) UniProt PMID:15327770 PMID:22158122 NCBI chr  X:23,428,343...23,489,688
Ensembl chr  X:30,980,841...31,012,994
JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:9013573) UniProt
MGI
PMID:9013573 NCBI chr 3:46,473,282...46,478,454
Ensembl chr 3:47,577,949...47,583,126
JBrowse link
G TGFA transforming growth factor alpha involved_in ISO (PMID:11278323) HGNC-UCL PMID:11278323 NCBI chr2A:70,510,727...70,617,628
Ensembl chr2A:71,625,196...71,731,461
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:14605008 RGD:1579859 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G THBS1 thrombospondin 1 involved_in ISO (PMID:17413041) BHF-UCL PMID:17413041 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G TLR4 toll like receptor 4 involved_in ISO (MGI:4421230|PMID:20051628) BHF-UCL PMID:20051628 MGI:4421230 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:10748004) BHF-UCL PMID:10748004 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TP73 tumor protein p73 ISO RGD PMID:17353261 RGD:2291838 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
G WNT5A Wnt family member 5A involved_in ISO (PMID:20034610) BHF-UCL PMID:20034610 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
activation of MAPKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:17704059) BHF-UCL PMID:17704059 NCBI chr 8:38,298,194...38,406,706
Ensembl chr 8:35,473,278...35,581,192
JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:12764156 RGD:1625267 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:17600318), (PMID:17992660) UniProt PMID:17600318 PMID:17992660 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in ISO (PMID:29433126) UniProt PMID:29433126 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115
JBrowse link
G CARTPT CART prepropeptide involved_in ISO PMID:15908120
(MGI:3696614|PMID:15908120)
HGNC-UCL PMID:15908120 MGI:3696614 RGD:8554672 NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229
JBrowse link
G EGF epidermal growth factor acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:14551192 RGD:1581912 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISO (PMID:15229216) UniProt PMID:15229216 NCBI chr2A:37,130,386...37,184,587
Ensembl chr2A:37,895,814...37,941,686
JBrowse link
G F2R coagulation factor II thrombin receptor ISO RGD PMID:12372796 RGD:728482 NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688
JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G GRM1 glutamate metabotropic receptor 1 involved_in ISO (MGI:1934687|PMID:11356865) UniProt PMID:11356865 MGI:1934687 NCBI chr 6:143,819,364...144,231,304
Ensembl chr 6:148,537,036...148,947,047
JBrowse link
G JAK2 Janus kinase 2 ISO insulin induced RGD PMID:16567515 RGD:1641817 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 acts_upstream_of_or_within ISO (MGI:3693387|PMID:15263099) MGI PMID:15263099 MGI:3693387 NCBI chr 1:131,396,937...131,400,695
Ensembl chr 1:135,226,400...135,230,167
JBrowse link
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 acts_upstream_of_or_within ISO (MGI:3693387|PMID:15263099) MGI PMID:15263099 MGI:3693387 NCBI chr 4:92,304,115...92,317,461
Ensembl chr 4:102,965,111...102,978,205
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in ISO (PMID:19302196) BHF-UCL PMID:19302196 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:7624324 PMID:9110999 RGD:1582177 RGD:2293488 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:11726277) UniProt PMID:11726277 NCBI chr 3:182,319,405...182,517,655
Ensembl chr 3:190,798,694...190,993,633
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:9305639), (PMID:9827804) UniProt PMID:9305639 PMID:9827804 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:11959862) BHF-UCL PMID:11959862 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:8663074), (PMID:9079627) RGD
UniProt
PMID:8663074 PMID:9079627 PMID:16183734 RGD:2298758 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (MGI:3579196|PMID:15896720) MGI PMID:15896720 MGI:3579196 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:10644344) AgBase PMID:10644344 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871
JBrowse link
G TAOK2 TAO kinase 2 involved_in ISO (PMID:10660600) UniProt PMID:10660600 Ensembl chr16:30,347,229...30,366,743 JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in ISO (PMID:18625725) BHF-UCL PMID:18625725 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
activation of MAPKKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:15190117) ARUK-UCL PMID:15190117 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:19903888) UniProt PMID:19903888 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:9827804) UniProt PMID:9827804 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta involved_in ISO (PMID:9827804) UniProt PMID:9827804 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma involved_in ISO (PMID:9827804) UniProt PMID:9827804 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958
JBrowse link
G GRM5 glutamate metabotropic receptor 5 involved_in ISO PMID:15758184 UniProt PMID:15758184 RGD:8554618 NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953
JBrowse link
G KSR1 kinase suppressor of ras 1 involved_in ISO (PMID:29433126) UniProt PMID:29433126 NCBI chr17:29,148,382...29,316,829
Ensembl chr17:29,649,105...29,720,651
JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:15310755) BHF-UCL PMID:15310755 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in ISO (PMID:14743216) UniProt PMID:14743216 NCBI chr16:1,013,831...1,036,486
Ensembl chr16:2,266,194...2,279,031
JBrowse link
activation of NF-kappaB-inducing kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (MGI:3844151|PMID:19404405) MGI PMID:19404405 MGI:3844151 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G CARD10 caspase recruitment domain family member 10 involved_in ISO (PMID:11259443) UniProt PMID:11259443 NCBI chr22:18,407,374...18,437,728
Ensembl chr22:36,240,898...36,268,546
JBrowse link
G CHI3L1 chitinase 3 like 1 involved_in ISO (MGI:5306542|PMID:21546314) UniProt PMID:21546314 MGI:5306542 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229
JBrowse link
G COPS8 COP9 signalosome subunit 8 involved_in ISO (PMID:22992343) UniProt PMID:22992343 NCBI chr2B:124,315,423...124,328,830
Ensembl chr2B:243,169,322...243,182,937
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma acts_upstream_of_or_within ISO (MGI:2682548|PMID:14654787) MGI PMID:14654787 MGI:2682548 NCBI chr  X:143,988,720...144,010,078
Ensembl chr  X:153,854,493...153,876,092
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (PMID:11397809) UniProt PMID:11397809 NCBI chr  X:143,560,802...143,570,185
Ensembl chr  X:153,446,827...153,460,602
JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 NOT|acts_upstream_of_or_within ISO (MGI:2388552|PMID:12220507) MGI PMID:12220507 MGI:2388552 NCBI chr 3:10,100,279...10,179,487
Ensembl chr 3:10,453,329...10,532,629
JBrowse link
G MALT1 MALT1 paracaspase involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:10094049), (PMID:15125833) UniProt PMID:10094049 PMID:15125833 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468
JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor acts_upstream_of_or_within ISO (MGI:3844151|PMID:19404405) MGI PMID:19404405 MGI:3844151 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393
JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:24275656) AgBase PMID:24275656 NCBI chr11:121,100,558...121,112,844
Ensembl chr11:125,018,064...125,022,309
JBrowse link
G TNFSF15 TNF superfamily member 15 acts_upstream_of_or_within ISO (PMID:11911831) MGI PMID:11911831 NCBI chr 9:85,881,800...85,904,191
Ensembl chr 9:114,249,472...114,265,441
JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 9:107,938,935...107,984,797
Ensembl chr 9:136,917,358...136,955,331
JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334
JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase involved_in ISO (PMID:20682767) UniProt PMID:20682767 NCBI chr11:53,833,437...53,875,435 JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY8 adenylate cyclase 8 involved_in ISO PMID:25381556 UniProt PMID:25381556 RGD:13825194 NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073
JBrowse link
G FBN1 fibrillin 1 involved_in ISO (PMID:27087445) UniProt PMID:27087445 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669
JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2B activin A receptor type 2B acts_upstream_of_or_within ISO (MGI:3701721|PMID:16806156) MGI PMID:16806156 MGI:3701721 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
JBrowse link
G ADNP activity dependent neuroprotector homeobox ISO Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr20:47,233,696...47,276,075
Ensembl chr20:48,361,043...48,400,387
JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:15653687) BHF-UCL PMID:15653687 NCBI chr10:107,669,860...107,673,685 JBrowse link
G AXIN1 axin 1 involved_in ISO (PMID:9601641) BHF-UCL PMID:9601641 Ensembl chr16:278,239...337,891 JBrowse link
G CAB39 calcium binding protein 39 acts_upstream_of_or_within ISO (MGI:3836081|PMID:18854309) MGI PMID:18854309 MGI:3836081 NCBI chr2B:117,965,688...118,074,063
Ensembl chr2B:236,809,549...236,870,646
JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in ISO (PMID:17983652) UniProt PMID:17983652 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
JBrowse link
G CAMKK1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:16054095 RGD:2311420 NCBI chr17:3,908,598...3,941,118
Ensembl chr17:3,900,458...3,930,010
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 ISO RGD PMID:16054095 RGD:2311420 NCBI chr12:118,835,862...118,896,918
Ensembl chr12:122,206,552...122,267,631
JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in ISO (PMID:21954290) UniProt PMID:21954290 NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362
JBrowse link
G CLSPN claspin involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chr 1:34,991,082...35,040,515
Ensembl chr 1:36,182,726...36,218,544
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within ISO (MGI:3697750|PMID:17187070) MGI PMID:17187070 MGI:3697750 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12086672 RGD:1580677 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G ECT2 epithelial cell transforming 2 involved_in ISO (PMID:15254234) UniProt PMID:15254234 NCBI chr 3:169,756,885...169,828,087
Ensembl chr 3:177,938,164...178,008,381
JBrowse link
G EMP2 epithelial membrane protein 2 involved_in ISO (PMID:21637765) UniProt PMID:21637765 NCBI chr16:9,465,589...9,517,593
Ensembl chr16:10,694,425...10,744,744
JBrowse link
G INSR insulin receptor involved_in ISO (PMID:9819385) BHF-UCL PMID:9819385 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G ITGB3 integrin subunit beta 3 involved_in ISO (PMID:10022831) BHF-UCL PMID:10022831 NCBI chr17:10,134,450...10,194,596 JBrowse link
G KIF14 kinesin family member 14 involved_in ISO (PMID:24784001) UniProt PMID:24784001 NCBI chr 1:176,156,870...176,223,093
Ensembl chr 1:180,462,578...180,526,323
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:16530387) UniProt PMID:16530387 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within ISO (MGI:3589325|PMID:16129705) MGI PMID:16129705 MGI:3589325 NCBI chr14:15,834,603...15,871,741
Ensembl chr14:34,020,893...34,056,842
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:10713049) ParkinsonsUK-UCL PMID:10713049 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PRNP prion protein involved_in ISO (MGI:5882868|PMID:23386614) ARUK-UCL PMID:23386614 MGI:5882868 NCBI chr20:4,713,616...4,728,847
Ensembl chr20:4,523,155...4,523,916
JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in ISO (PMID:22817896) UniProt PMID:22817896 NCBI chr14:5,112,512...5,116,486
Ensembl chr14:23,235,796...23,239,821
JBrowse link
G SLC11A1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO (MGI:64652|PMID:8301134) MGI PMID:8301134 MGI:64652 NCBI chr2B:105,640,613...105,655,524
Ensembl chr2B:224,238,284...224,252,941
JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within
ISO (PMID:15731909)
(PMID:18854309)
(MGI:3836081|PMID:18854309)
UniProt
MGI
PMID:15731909 PMID:18854309 MGI:3836081 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G STRADA STE20 related adaptor alpha involved_in
acts_upstream_of_or_within
ISO (PMID:12805220)
(MGI:3836081|PMID:18854309)
PMID:14511394
UniProt
MGI
PMID:12805220 PMID:14511394 PMID:18854309 MGI:3836081 RGD:1600691 NCBI chr17:57,783,114...57,822,056
Ensembl chr17:62,929,065...62,967,021
JBrowse link
G STRADB STE20 related adaptor beta involved_in ISO (PMID:14517248) UniProt PMID:14517248 NCBI chr2B:88,705,840...88,735,511
Ensembl chr2B:206,864,319...206,890,868
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:17192487), (PMID:17960115) BHF-UCL PMID:17192487 PMID:17960115 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 acts_upstream_of_or_within ISO (MGI:3701721|PMID:16806156) MGI PMID:16806156 MGI:3701721 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G TOM1L1 target of myb1 like 1 membrane trafficking protein involved_in ISO (PMID:16479011) UniProt PMID:16479011 NCBI chr17:48,990,121...49,050,703
Ensembl chr17:53,855,447...53,916,592
JBrowse link
G TPX2 TPX2 microtubule nucleation factor involved_in ISO (PMID:14580337), (PMID:19801554) UniProt PMID:14580337 PMID:19801554 NCBI chr20:28,032,663...28,095,223
Ensembl chr20:29,163,312...29,225,860
JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) UniProt PMID:17135271 NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:18059339), (PMID:20497126) BHF-UCL PMID:18059339 PMID:20497126 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:17215105) BHF-UCL PMID:17215105 NCBI chr10:107,669,860...107,673,685 JBrowse link
G ADRA2B adrenoceptor alpha 2B involved_in ISO (PMID:17215105) BHF-UCL PMID:17215105 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472
JBrowse link
G ADRA2C adrenoceptor alpha 2C involved_in ISO (PMID:17215105) BHF-UCL PMID:17215105 NCBI chr 4:3,904,346...3,906,577 JBrowse link
G ANG angiogenin involved_in ISO (PMID:17125737) UniProt PMID:17125737 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393
JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in ISO (MGI:3581096|PMID:15753085) UniProt PMID:15753085 MGI:3581096 NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362
JBrowse link
G DYNAP dynactin associated protein involved_in ISO (PMID:20978158) UniProt PMID:20978158 NCBI chr18:47,955,919...47,979,145 JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISO (PMID:18441324) UniProt PMID:18441324 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001
JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:22351760) UniProt PMID:22351760 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IL18 interleukin 18 involved_in ISO (PMID:21321938) BHF-UCL PMID:21321938 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G INS insulin involved_in ISO (PMID:8702995) BHF-UCL PMID:8702995 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G INSR insulin receptor involved_in ISO (PMID:7556070) BHF-UCL PMID:7556070 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155
JBrowse link
G MT3 metallothionein 3 involved_in ISO (PMID:18295594) UniProt PMID:18295594 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093
JBrowse link
G NRG1 neuregulin 1 involved_in ISO (PMID:20682778) UniProt PMID:20682778 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G NTF3 neurotrophin 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204
JBrowse link
G OSBPL8 oxysterol binding protein like 8 involved_in ISO (MGI:5644010|PMID:23812417) BHF-UCL PMID:23812417 MGI:5644010 NCBI chr12:73,870,094...74,078,073
Ensembl chr12:76,720,276...76,820,830
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:16530387) UniProt PMID:16530387 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:9368760) BHF-UCL PMID:9368760 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:23180369) UniProt PMID:23180369 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PRKCZ protein kinase C zeta ISO in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in ISO (MGI:6478088|PMID:23827345) MGI PMID:23827345 MGI:6478088 NCBI chr 9:4,323,124...4,420,193
Ensembl chr 9:4,511,491...4,608,337
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TCL1A TCL1 family AKT coactivator A involved_in ISO (MGI:6377804|PMID:28262547) CACAO PMID:28262547 MGI:6377804 NCBI chr14:76,339,614...76,343,546
Ensembl chr14:95,664,120...95,667,375
JBrowse link
G WNT5A Wnt family member 5A involved_in ISO (PMID:20034610) BHF-UCL PMID:20034610 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
activation of protein kinase C activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:10713049) ParkinsonsUK-UCL PMID:10713049 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G CD86 CD86 molecule involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
G LEP leptin involved_in ISO (PMID:24340098) UniProt PMID:24340098 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G PHB prohibitin involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790
JBrowse link
G PHB2 prohibitin 2 involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
activation of transmembrane receptor protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in ISO (PMID:19424712) UniProt PMID:19424712 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO (MGI:3590443|PMID:16162937) MGI PMID:16162937 MGI:3590443 NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044
JBrowse link
G NRG1 neuregulin 1 involved_in ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G PDGFC platelet derived growth factor C acts_upstream_of_or_within ISO (MGI:1858279|PMID:10806482) MGI PMID:10806482 MGI:1858279 NCBI chr 4:149,105,330...149,317,254
Ensembl chr 4:160,922,827...161,131,960
JBrowse link
G PRLR prolactin receptor involved_in ISO (PMID:10585417) UniProt PMID:10585417 NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403
JBrowse link
inactivation of MAPK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 involved_in ISO (PMID:22375048) UniProt PMID:22375048 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720
JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in ISO (PMID:16604064) UniProt PMID:16604064 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045
JBrowse link
G DUSP4 dual specificity phosphatase 4 involved_in ISO (PMID:7535768) UniProt PMID:7535768 NCBI chr 8:28,623,777...28,641,432
Ensembl chr 8:25,819,989...25,834,332
JBrowse link
G DUSP6 dual specificity phosphatase 6 involved_in ISO (PMID:8670865) UniProt PMID:8670865 NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321
JBrowse link
G DUSP8 dual specificity phosphatase 8 involved_in ISO (MGI:5788647|PMID:7561881) UniProt PMID:7561881 MGI:5788647 NCBI chr11:1,592,858...1,611,740 JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 involved_in ISO (PMID:12359715) HGNC-UCL PMID:12359715 NCBI chr 1:179,370,097...179,379,618
Ensembl chr 1:183,660,297...183,671,335
JBrowse link
inactivation of MAPKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHB2 EPH receptor B2 involved_in ISO (MGI:5905277|PMID:11585923) ARUK-UCL PMID:11585923 MGI:5905277 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118
JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO (PMID:12556535) UniProt PMID:12556535 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr10:22,691,355...22,870,628 JBrowse link
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr17:18,471,609...18,507,916
Ensembl chr17:18,746,712...18,782,296
JBrowse link
G PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr12:31,323,346...31,335,626
Ensembl chr12:31,584,534...31,594,808
JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (PMID:16254138) UniProt PMID:16254138 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536
JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G HPN hepsin acts_upstream_of_or_within ISO (MGI:5437809|PMID:22912808) MGI PMID:22912808 MGI:5437809 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628
JBrowse link
G SEMA4D semaphorin 4D involved_in ISO (PMID:22019888)
(MGI:5297297|PMID:22019888)
BHF-UCL PMID:22019888 MGI:5297297 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:18358889) BHF-UCL PMID:18358889 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TNF tumor necrosis factor involved_in ISO (MGI:5285024|PMID:21689636) BHF-UCL PMID:21689636 MGI:5285024 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:92,365,267...92,511,852
Ensembl chr10:95,828,094...95,983,257
JBrowse link
G FLCN folliculin involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr2B:116,265,529...116,517,557 JBrowse link
negative regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKIA cAMP-dependent protein kinase inhibitor alpha involved_in
acts_upstream_of_or_within
ISO (PMID:21812984)
(PMID:7905001)
BHF-UCL
MGI
PMID:7905001 PMID:21812984 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta acts_upstream_of_or_within ISO (MGI:3793555|PMID:7905001) MGI PMID:7905001 MGI:3793555 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943
JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr 7:700,691...876,497
Ensembl chr 7:923,668...1,097,456
JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394)
(PMID:21812984)
AgBase
BHF-UCL
PMID:21812984 PMID:22674394 NCBI chr 3:48,665,421...48,774,111
Ensembl chr 3:49,747,611...49,854,382
JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr 7:99,021,209...99,140,652
Ensembl chr 7:111,748,463...111,866,044
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:20203304) UniProt PMID:20203304 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 involved_in ISO (PMID:18305109) UniProt PMID:18305109 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:8876165) CAFA PMID:8876165 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:8684460) CAFA PMID:8684460 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:11746698) CAFA PMID:11746698 NCBI chr11:2,908,537...2,911,134 JBrowse link
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway involved_in ISO (PMID:8521819) UniProt PMID:8521819 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G CASP3 caspase 3 acts_upstream_of_or_within ISO (MGI:2677082|PMID:12970760) MGI PMID:12970760 MGI:2677082 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 involved_in ISO (PMID:11882646) UniProt PMID:11882646 NCBI chr20:29,648,003...29,690,210
Ensembl chr20:30,762,967...30,804,237
JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO RGD PMID:10721722 RGD:632478 NCBI chr 9:91,519,179...91,707,469
Ensembl chr 9:119,868,015...120,055,608
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:2183076|PMID:12130539) MGI PMID:12130539 MGI:2183076 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in
ISO (MGI:2183076|PMID:12130539)
(PMID:28666995)
RGD
MGI
UniProt
PMID:12130539 PMID:22584582 PMID:28666995 MGI:2183076 RGD:10045364 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in
ISO (MGI:2183076|PMID:12130539)
(PMID:7739547)
(PMID:8259215)
MGI
BHF-UCL
PMID:7739547 PMID:8259215 PMID:12130539 MGI:2183076 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (MGI:72259|PMID:7739547) MGI PMID:7739547 MGI:72259 NCBI chr 1:50,214,767...50,221,465
Ensembl chr 1:51,704,528...51,718,374
JBrowse link
G FBXO7 F-box protein 7 acts_upstream_of_or_within ISO (MGI:5317390|PMID:21652635) MGI PMID:21652635 MGI:5317390 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:14580347) HGNC-UCL PMID:14580347 NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669
JBrowse link
G HEXIM2 HEXIM P-TEFb complex subunit 2 involved_in ISO (PMID:15713662) HGNC-UCL PMID:15713662 NCBI chr17:12,157,392...12,167,281
Ensembl chr17:12,333,957...12,343,399
JBrowse link
G HHEX hematopoietically expressed homeobox involved_in ISO (PMID:12554669) BHF-UCL PMID:12554669 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO (MGI:5286822|PMID:21540187)
(PMID:21540187)
MGI PMID:21540187 MGI:5286822 NCBI chr17:5,036,659...5,046,146
Ensembl chr17:5,024,740...5,034,216
JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in ISO (MGI:4410401|PMID:19773423) UniProt PMID:19773423 MGI:4410401 NCBI chr 3:19,956,067...20,070,637
Ensembl chr 3:20,286,865...20,400,770
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in ISO (PMID:9988268) UniProt PMID:9988268 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276
JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) UniProt PMID:12853976 NCBI chr13:2,300,625...2,389,027
Ensembl chr13:20,611,861...20,683,083
JBrowse link
G MEN1 menin 1 involved_in ISO (PMID:15640349) UniProt PMID:15640349 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G MYOCD myocardin involved_in ISO (PMID:18451334) BHF-UCL PMID:18451334 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659
JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 involved_in ISO (PMID:19210544) BHF-UCL PMID:19210544 NCBI chr15:75,008,879...75,021,981 JBrowse link
G PLK1 polo like kinase 1 involved_in ISO (PMID:21041660) BHF-UCL PMID:21041660 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G TFAP4 transcription factor AP-4 involved_in ISO (PMID:18818310) UniProt PMID:18818310 NCBI chr16:3,176,129...3,226,404
Ensembl chr16:4,348,929...4,368,525
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in ISO (MGI:4943408|PMID:15962316) BHF-UCL PMID:15962316 MGI:4943408 NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819
JBrowse link
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (MGI:4948986|PMID:21454751) UniProt PMID:21454751 MGI:4948986 NCBI chr 7:133,635,359...133,663,153
Ensembl chr 7:146,110,121...146,132,872
JBrowse link
negative regulation of dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPM2A EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) UniProt PMID:18617530 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (MGI:5294535|PMID:19250614) UniProt PMID:19250614 MGI:5294535 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 acts_upstream_of_or_within ISO (MGI:5085959|PMID:21709260) MGI PMID:21709260 MGI:5085959 NCBI chr15:69,076,025...69,190,082
Ensembl chr15:88,276,851...88,388,594
JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO (PMID:22064321)
(MGI:5617428|PMID:25329545)
ParkinsonsUK-UCL
UniProt
PMID:22064321 PMID:25329545 MGI:5617428 NCBI chr13:76,853,053...76,963,530
Ensembl chr13:96,033,605...96,114,165
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in ISO (PMID:14676213), (PMID:16835242)
(MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
ParkinsonsUK-UCL PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (PMID:16835242)
(MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
ParkinsonsUK-UCL PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:5613475 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:5613475 NCBI chr 1:180,002,895...180,014,956
Ensembl chr 1:184,293,640...184,302,316
JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (MGI:5914333|PMID:28797121) MGI PMID:28797121 MGI:5914333 NCBI chr12:121,169,915...121,183,524
Ensembl chr12:125,397,391...125,410,794
JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO (PMID:18046415)
(MGI:3629275|PMID:16648858)
PMID:17599051
UniProt PMID:16648858 PMID:17599051 PMID:18046415 MGI:3629275 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A involved_in ISO (MGI:5635952|PMID:25744720) UniProt PMID:25744720 MGI:5635952 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727
JBrowse link
G PSEN1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
G TSG101 tumor susceptibility 101 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149
JBrowse link
G VPS25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:14,538,322...14,544,573
Ensembl chr17:14,763,523...14,769,672
JBrowse link
G ZFYVE28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) UniProt PMID:19460345 NCBI chr 4:2,412,659...2,564,741
Ensembl chr 4:2,320,446...2,470,638
JBrowse link
G ZGPAT zinc finger CCCH-type and G-patch domain containing involved_in ISO (PMID:19644445) UniProt PMID:19644445 Ensembl chr20:61,630,271...61,662,967 JBrowse link
negative regulation of glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXA2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) BHF-UCL PMID:11875061 MGI:5142372 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GCKR glucokinase regulator involved_in
acts_upstream_of_or_within
ISO PMID:14627435
(MGI:1354534|PMID:10713097)
(PMID:14627435), (PMID:23621087)
BHF-UCL
MGI
PMID:10713097 PMID:14627435 PMID:23621087 MGI:1354534 RGD:1598592 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927
JBrowse link
G LOC100976343 cytochrome c oxidase assembly protein COX11, mitochondrial acts_upstream_of_or_within ISO (MGI:3693040|PMID:17069463) MGI PMID:17069463 MGI:3693040 NCBI chr17:49,009,099...49,058,145
Ensembl chr17:53,915,841...53,923,431
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:24187134) MGI PMID:24187134 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chr16:69,592,293...69,662,321
Ensembl chr16:89,246,545...89,347,435
JBrowse link
G DDIT4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (MGI:4440406|PMID:20176937) MGI PMID:20176937 MGI:4440406 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in ISO (PMID:25043030)
(PMID:19881551)
CAFA
UniProt
PMID:19881551 PMID:25043030 NCBI chr 9:65,695,082...65,731,628
Ensembl chr 9:93,825,150...93,860,968
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in ISO (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857
JBrowse link
G HDAC4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) MGI PMID:19096392 MGI:4437986 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (MGI:5662300|PMID:26219591) MGI PMID:26219591 MGI:5662300 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 1:178,684,933...178,687,971
Ensembl chr 1:182,979,700...182,982,611
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:34,934,452...35,121,195 JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:30451898) UniProt PMID:30451898 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) CACAO PMID:20141841 PMID:23217706 MGI:4881401 MGI:5619441 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5441121|PMID:22891351) MGI PMID:22891351 MGI:5441121 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (MGI:3820439|PMID:18698006) MGI PMID:18698006 MGI:3820439 NCBI chr17:13,131,851...13,150,872
Ensembl chr17:13,302,796...13,317,312
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524
JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)
UniProt PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr 1:187,044,054...187,060,441
Ensembl chr 1:191,907,989...191,924,365
JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCKR glucokinase regulator ISO RGD PMID:14627435 RGD:1598592 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927
JBrowse link
negative regulation of histone phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100974858 core histone macro-H2A.1 involved_in ISO (PMID:22194607) UniProt PMID:22194607 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) BHF-UCL PMID:17690110 NCBI chr 7:19,761,041...19,765,665 JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B acts_upstream_of_or_within ISO (MGI:3720437|PMID:17488778) MGI PMID:17488778 MGI:3720437 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLEK pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) BHF-UCL PMID:7559487 PMID:7782310 NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:7535379 RGD:7777104 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated acts_upstream_of_or_within ISO (MGI:3799599|PMID:17681137)
(PMID:17681137)
MGI PMID:17681137 MGI:3799599 NCBI chr 1:198,341,375...198,385,682 JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:24512202) UniProt PMID:24512202 NCBI chr 9:32,800,077...32,814,745
Ensembl chr 9:33,608,502...33,622,275
JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within
ISO (PMID:10391943)
(MGI:3051749|PMID:15306813)
BHF-UCL
MGI
PMID:10391943 PMID:15306813 MGI:3051749 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720
JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664)
(MGI:5009198|PMID:10945608), (MGI:5009411|PMID:16023107)
(MGI:3721484|PMID:12646564)
BHF-UCL PMID:10945608 PMID:12646564 PMID:16023107 PMID:16636664 MGI:3721484 MGI:5009198 MGI:5009411 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 involved_in ISO (MGI:1913166|PMID:11034606) UniProt PMID:11034606 MGI:1913166 NCBI chr11:33,230,731...33,330,617
Ensembl chr11:33,114,534...33,212,783
JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO PMID:21076496 RGD
UniProt
PMID:12064607 PMID:21076496 RGD:1299562 RGD:13673827 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010
JBrowse link
G NPPA natriuretic peptide A involved_in ISO (PMID:22399583) UniProt PMID:22399583 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr10:94,383,269...94,389,053
Ensembl chr10:97,877,790...97,882,850
JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) MGI PMID:15483136 MGI:3574697 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein acts_upstream_of_or_within ISO (MGI:3581335|PMID:15870270) MGI PMID:15870270 MGI:3581335 NCBI chr14:3,791,309...3,802,763
Ensembl chr14:21,889,443...21,900,700
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031
JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (MGI:3851274|PMID:19523444) BHF-UCL PMID:19523444 MGI:3851274 NCBI chr13:90,886,095...90,917,724 JBrowse link
G LOC100995589 uncharacterized LOC100995589 involved_in ISO (PMID:24391509) UniProt PMID:24391509 NCBI chr2A:15,923,366...15,926,680 JBrowse link
G MAPT microtubule associated protein tau involved_in ISO (PMID:20655099) ParkinsonsUK-UCL PMID:20655099 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G MSTN myostatin involved_in ISO (MGI:5619470|PMID:19357233) CACAO PMID:19357233 MGI:5619470 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922
JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit involved_in ISO (PMID:18616680) UniProt PMID:18616680 NCBI chr 3:50,273,611...50,277,175
Ensembl chr 3:51,508,932...51,512,776
JBrowse link
G PRDX3 peroxiredoxin 3 involved_in ISO (PMID:18205602) UniProt PMID:18205602 NCBI chr10:115,738,346...115,749,482
Ensembl chr10:119,162,714...119,173,845
JBrowse link
G PRPSAP1 phosphoribosyl pyrophosphate synthetase associated protein 1 ISO RGD PMID:9366267 RGD:5134981 NCBI chr17:70,258,663...70,302,287
Ensembl chr17:75,810,423...75,853,442
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr12:825,659...985,016
Ensembl chr12:791,153...944,602
JBrowse link
negative regulation of lipid kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP2R5A protein phosphatase 2 regulatory subunit B'alpha involved_in ISO (PMID:21075214) BHF-UCL PMID:21075214 NCBI chr 1:187,853,674...187,926,318
Ensembl chr 1:192,716,546...192,788,328
JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (MGI:4943654|PMID:19460854) UniProt PMID:19460854 MGI:4943654 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AGT angiotensinogen involved_in ISO (PMID:28283184) CACAO PMID:28283184 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:9685360) BHF-UCL PMID:9685360 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (MGI:3703676|PMID:12388746) MGI PMID:12388746 MGI:3703676 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CAV3 caveolin 3 involved_in ISO (PMID:12847114) BHF-UCL PMID:12847114 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:16254138) UniProt PMID:16254138 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:21283629) UniProt PMID:21283629 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:12813029)
(PMID:20154697)
BHF-UCL PMID:12813029 PMID:20154697 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G DEFB114 defensin beta 114 involved_in ISO (PMID:23482568) UniProt PMID:23482568 NCBI chr 6:49,527,541...49,531,451
Ensembl chr 6:50,787,203...50,791,015
JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in ISO (PMID:7593328) UniProt PMID:7593328 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP7 dual specificity phosphatase 7 involved_in ISO (PMID:9788880) UniProt PMID:9788880 NCBI chr 3:51,990,115...51,997,627
Ensembl chr 3:53,219,167...53,226,491
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17182785 RGD:2301767 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:11408560) BHF-UCL PMID:11408560 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase acts_upstream_of_or_within ISO (MGI:3610917|PMID:12409258) MGI PMID:12409258 MGI:3610917 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785
JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551
JBrowse link
G IL1B interleukin 1 beta involved_in ISO (MGI:3828398|PMID:16865359) BHF-UCL PMID:16865359 MGI:3828398 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:17379480)
(MGI:3843426|PMID:17379480)
BHF-UCL PMID:17379480 MGI:3843426 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148
JBrowse link
G KNG1 kininogen 1 ISO in ConA- or PHA-stimulated Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
G LOC100973655 protein fem-1 homolog A acts_upstream_of_or_within ISO (MGI:3790904|PMID:18270204) MGI PMID:18270204 MGI:3790904 NCBI chr21:468,156...495,596
Ensembl chr19:4,763,674...4,765,683
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:894972|PMID:9252121) UniProt PMID:9252121 MGI:894972 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 acts_upstream_of_or_within ISO (MGI:1933463|PMID:11139578), (MGI:2135469|PMID:11381262) MGI PMID:11139578 PMID:11381262 MGI:1933463 MGI:2135469 NCBI chr17:31,729,429...31,736,216
Ensembl chr17:36,894,146...36,899,969
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:1932841|PMID:11297510)
(MGI:3610917|PMID:12409258)
(MGI:1351242|PMID:10620616)
MGI PMID:10620616 PMID:11297510 PMID:12409258 MGI:1351242 MGI:1932841 MGI:3610917 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (MGI:3526674|PMID:11489947) UniProt PMID:11489947 MGI:3526674 NCBI chr19:46,919,731...46,942,318 JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (MGI:3722998|PMID:17724343)
(PMID:17724343)
MGI PMID:17724343 MGI:3722998 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in ISO (MGI:6444553|PMID:30496354) BHF-UCL PMID:30496354 MGI:6444553 NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:22045810) CACAO PMID:22045810 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 RGD:10044039 NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656), (MGI:82729|PMID:9064344) MGI PMID:9064344 PMID:9254656 MGI:1095647 MGI:82729 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:19494114)
(MGI:4942250|PMID:12833140)
UniProt PMID:12833140 PMID:19494114 MGI:4942250 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G RGS14 regulator of G protein signaling 14 involved_in ISO (MGI:4834960|PMID:20837545) UniProt PMID:20837545 MGI:4834960 NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453
JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in ISO (MGI:3510267|PMID:15337790) ARUK-UCL PMID:15337790 MGI:3510267 NCBI chr12:108,977,344...109,024,029 JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SORL1 sortilin related receptor 1 involved_in ISO (MGI:3801250|PMID:18362153) Alzheimers_University_of_Toronto PMID:18362153 MGI:3801250 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 5:137,667,280...137,683,578
Ensembl chr 5:143,778,785...143,791,939
JBrowse link
G STK38 serine/threonine kinase 38 involved_in ISO (PMID:17906693) UniProt PMID:17906693 NCBI chr 6:36,056,585...36,110,531
Ensembl chr 6:37,255,183...37,308,102
JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:14612383 RGD:1580517 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:19477270) BHF-UCL PMID:19477270 NCBI chr 4:35,580,755...35,592,314
Ensembl chr 4:41,428,759...41,440,129
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr 8:41,515,613...41,576,229
Ensembl chr 8:38,960,594...39,020,971
JBrowse link
G MPRIP myosin phosphatase Rho interacting protein ISO RGD PMID:17661354 RGD:9685557 NCBI chr17:34,101,451...34,251,475
Ensembl chr17:39,040,719...39,182,578
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:16417406) UniProt PMID:16417406 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986
JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP22 dual specificity phosphatase 22 involved_in ISO (PMID:20018849) ARUK-UCL PMID:20018849 NCBI chr 6:107,145...180,777
Ensembl chr 6:242,121...301,248
JBrowse link
negative regulation of nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDA cytidine deaminase involved_in ISO (PMID:9596658) UniProt PMID:9596658 NCBI chr 1:19,538,696...19,568,008
Ensembl chr 1:20,583,441...20,612,711
JBrowse link
negative regulation of pathway-restricted SMAD protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:5605894 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525
JBrowse link
G ENG endoglin involved_in ISO (PMID:18974388) BHF-UCL PMID:18974388 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:11,213,870...11,230,619 JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) UniProt PMID:24627487 NCBI chr18:669,862...1,110,558
Ensembl chr18:2,845,198...2,879,363
JBrowse link
G NOG noggin involved_in ISO (PMID:15539560)
(MGI:3783944|PMID:17218603)
BHF-UCL PMID:15539560 PMID:17218603 MGI:3783944 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in ISO (PMID:24627487)
(MGI:5582164|PMID:20129061)
(PMID:20129061)
UniProt PMID:20129061 PMID:24627487 MGI:5582164 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G SMAD6 SMAD family member 6 involved_in ISO (PMID:19047146)
(PMID:9436979)
BHF-UCL PMID:9436979 PMID:19047146 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:17438144) BHF-UCL PMID:17438144 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SNX25 sorting nexin 25 involved_in ISO (PMID:21266196) UniProt PMID:21266196 NCBI chr 4:177,377,302...177,529,601
Ensembl chr 4:189,631,239...189,746,590
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of peptidyl-serine dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in ISO (PMID:25007873) GO_Central PMID:25007873 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 involved_in ISO (MGI:5554982|PMID:23921380) CACAO PMID:23921380 MGI:5554982 NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of peptidyl-serine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:3527292|PMID:15613488) MGI PMID:15613488 MGI:3527292 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:3527292|PMID:15613488) MGI PMID:15613488 MGI:3527292 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BDKRB2 bradykinin receptor B2 acts_upstream_of_or_within ISO (MGI:3654719|PMID:16571598) MGI PMID:16571598 MGI:3654719 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:18081315) BHF-UCL PMID:18081315 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CNKSR3 CNKSR family member 3 involved_in ISO (MGI:4457233|PMID:19567370) UniProt PMID:19567370 MGI:4457233 NCBI chr 6:152,221,458...152,326,885 JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in ISO PMID:19118169 UniProt PMID:19118169 RGD:8554415 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20723538) BHF-UCL PMID:20723538 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G DMD dystrophin involved_in ISO (MGI:5487906|PMID:23263329) BHF-UCL PMID:23263329 MGI:5487906 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO (MGI:3826692|PMID:18824542) MGI PMID:18824542 MGI:3826692 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:19666841) BHF-UCL PMID:19666841 NCBI chr 3:32,026,586...32,088,512
Ensembl chr 3:32,342,776...32,404,172
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO Akt1 RGD PMID:26660861 RGD:13514041 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G HGF hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:4849876|PMID:21072211) MGI PMID:21072211 MGI:4849876 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F involved_in ISO PMID:26908121 ParkinsonsUK-UCL PMID:26908121 RGD:11059577 NCBI chr10:116,295,802...116,396,764
Ensembl chr10:119,712,696...119,813,444
JBrowse link
G INPP5J inositol polyphosphate-5-phosphatase J acts_upstream_of_or_within ISO (MGI:3654813|PMID:16280363) MGI PMID:16280363 MGI:3654813 NCBI chr22:12,131,746...12,158,481
Ensembl chr22:29,984,096...29,995,256
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in
acts_upstream_of_or_within
ISO (PMID:12556481)
(MGI:3810008|PMID:18573875)
(MGI:5294535|PMID:19250614)
UniProt
MGI
PMID:12556481 PMID:18573875 PMID:19250614 MGI:3810008 MGI:5294535 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G MLXIPL MLX interacting protein like involved_in ISO (PMID:19995986) BHF-UCL PMID:19995986 Ensembl chr 7:80,745,765...80,776,153 JBrowse link
G NCK1 NCK adaptor protein 1 involved_in ISO (PMID:14676213), (PMID:16835242) ParkinsonsUK-UCL PMID:14676213 PMID:16835242 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (PMID:16835242) ParkinsonsUK-UCL PMID:16835242 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in ISO (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:49,995,556...49,998,734 JBrowse link
G NOS1 nitric oxide synthase 1 involved_in ISO PMID:19278978 BHF-UCL PMID:19278978 RGD:10047220 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO Akt1 RGD PMID:21712532 RGD:9590189 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (PMID:17724343) MGI PMID:17724343 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:15140879) UniProt PMID:15140879 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:10918569) UniProt PMID:10918569 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in ISO (PMID:20103773) ParkinsonsUK-UCL PMID:20103773 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128
JBrowse link
G RASSF2 Ras association domain family member 2 acts_upstream_of_or_within ISO (PMID:19962960) MGI PMID:19962960 NCBI chr20:4,804,802...4,845,633
Ensembl chr20:4,603,414...4,641,529
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:18593713)
(MGI:5532916|PMID:18593713)
BHF-UCL PMID:18593713 MGI:5532916 NCBI chr18:42,306,324...42,337,214 JBrowse link
negative regulation of peptidyl-serine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:23329839)
(MGI:6377865|PMID:23329839)
CACAO PMID:23329839 MGI:6377865 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (MGI:5779255|PMID:26764350) MGI PMID:26764350 MGI:5779255 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055
JBrowse link
G PWP1 PWP1 homolog, endonuclein acts_upstream_of_or_within ISO (MGI:5659778|PMID:25335925) MGI PMID:25335925 MGI:5659778 NCBI chr12:105,255,755...105,282,519
Ensembl chr12:108,652,024...108,679,503
JBrowse link
negative regulation of peptidyl-threonine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM4 cell adhesion molecule 4 involved_in ISO (PMID:23611113)
(MGI:6270911|PMID:23611113)
UniProt PMID:23611113 MGI:6270911 NCBI chr19:40,564,288...40,581,830 JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in ISO PMID:19118169 UniProt PMID:19118169 RGD:8554415 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DGKQ diacylglycerol kinase theta involved_in ISO (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724
JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:18426977) ParkinsonsUK-UCL PMID:18426977 NCBI chr 3:181,351,938...181,372,776
Ensembl chr 3:189,833,490...189,855,060
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO Akt1 RGD PMID:26660861 RGD:13514041 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO MAP2 RGD PMID:18262389 RGD:2317458 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO Akt1 RGD PMID:21712532 RGD:9590189 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PARD3 par-3 family cell polarity regulator involved_in ISO (MGI:5295137|PMID:21949390) UniProt PMID:21949390 MGI:5295137 NCBI chr10:34,225,791...34,933,907
Ensembl chr10:34,808,380...35,393,287
JBrowse link
G PPEF2 protein phosphatase with EF-hand domain 2 involved_in ISO (PMID:20674765) BHF-UCL PMID:20674765 NCBI chr 4:48,308,761...48,345,861
Ensembl chr 4:54,141,778...54,184,351
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Tsc2 RGD PMID:21925170 RGD:9999170 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:17301223 RGD:13515116 NCBI chr 6:42,576,759...42,604,609
Ensembl chr 6:43,871,915...43,899,183
JBrowse link
G SIRT2 sirtuin 2 involved_in ISO (MGI:5295137|PMID:21949390) UniProt PMID:21949390 MGI:5295137 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:18593713)
(MGI:5532916|PMID:18593713)
BHF-UCL PMID:18593713 MGI:5532916 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in ISO (PMID:20736167)
(MGI:5318016|PMID:20736167)
BHF-UCL PMID:20736167 MGI:5318016 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (PMID:20736167)
(MGI:5318016|PMID:20736167)
BHF-UCL PMID:20736167 MGI:5318016 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:20736167) BHF-UCL PMID:20736167 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928
JBrowse link
negative regulation of peptidyl-tyrosine autophosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in ISO (PMID:25006397)
(MGI:5607357|PMID:25017399)
BHF-UCL PMID:25006397 PMID:25017399 MGI:5607357 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
negative regulation of peptidyl-tyrosine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM4 cell adhesion molecule 4 involved_in ISO (PMID:23611113)
(MGI:6270911|PMID:23611113)
UniProt PMID:23611113 MGI:6270911 NCBI chr19:40,564,288...40,581,830 JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO PMID:17599051 UniProt PMID:17599051 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:5433272|PMID:21677284) MGI PMID:21677284 MGI:5433272 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:22001439 RGD:8655996 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G LRRK1 leucine rich repeat kinase 1 acts_upstream_of_or_within ISO (MGI:5564766|PMID:23526378) MGI PMID:23526378 MGI:5564766 NCBI chr15:79,642,908...79,793,990
Ensembl chr15:98,931,344...99,081,168
JBrowse link
G NTF3 neurotrophin 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (MGI:3843438|PMID:14583092) BHF-UCL PMID:14583092 MGI:3843438 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PRKCZ protein kinase C zeta involved_in ISO (PMID:15069075) BHF-UCL PMID:15069075 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
ISO (PMID:19749791)
(MGI:1095647|PMID:9254656)
BHF-UCL
MGI
PMID:9254656 PMID:19749791 MGI:1095647 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277) MGI PMID:7499277 PMID:8175795 MGI:65996 MGI:77358 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 involved_in ISO (MGI:4437539|PMID:19923443) UniProt PMID:19923443 MGI:4437539 NCBI chr21:1,228,632...1,399,331
Ensembl chr21:14,595,688...14,711,613
JBrowse link
G SEMA4D semaphorin 4D involved_in ISO (MGI:5297297|PMID:22019888) BHF-UCL PMID:22019888 MGI:5297297 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in ISO (PMID:10980594) UniProt PMID:10980594 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in ISO (MGI:4835154|PMID:10980594) UniProt PMID:10980594 MGI:4835154 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (MGI:5428115|PMID:22228629) MGI PMID:22228629 MGI:5428115 NCBI chr 5:143,273,137...143,287,745 JBrowse link
negative regulation of phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO (PMID:10593895) UniProt PMID:10593895 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) UniProt PMID:18617530 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G URI1 URI1 prefoldin like chaperone involved_in ISO (PMID:17936702) UniProt PMID:17936702 NCBI chr19:26,865,190...26,939,510
Ensembl chr19:35,601,872...35,694,273
JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPCAT1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (MGI:4460850|PMID:20018880) MGI PMID:20018880 MGI:4460850 NCBI chr 5:1,759,243...1,824,102
Ensembl chr 5:1,503,853...1,544,741
JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chr19:41,862,168...41,878,231 JBrowse link
negative regulation of phosphatidylinositol 3-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:19903888) UniProt PMID:19903888 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 involved_in ISO (PMID:17475214)
(MGI:3806716|PMID:18632611)
UniProt PMID:17475214 PMID:18632611 MGI:3806716 NCBI chr22:12,305,518...12,316,434
Ensembl chr22:30,141,326...30,152,397
JBrowse link
G RUBCN rubicon autophagy regulator involved_in ISO (PMID:21062745) UniProt PMID:21062745 NCBI chr 3:195,088,936...195,166,771
Ensembl chr 3:204,973,968...205,034,011
JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) UniProt PMID:21712384 MGI:5292318 NCBI chr 8:37,479,231...37,515,303
Ensembl chr 8:34,656,000...34,692,666
JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in ISO PMID:24201375
(PMID:24201375)
ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) UniProt PMID:19523918 NCBI chr19:16,956,000...16,993,429
Ensembl chr19:17,929,785...17,966,171
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOD1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) UniProt PMID:24157919 NCBI chr 5:168,951,787...168,960,934
Ensembl chr 5:175,857,814...175,866,951
JBrowse link
G CMYA5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) MGI PMID:21427212 MGI:5056263 NCBI chr 5:35,515,463...35,620,430
Ensembl chr 5:35,787,369...35,890,641
JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in ISO (PMID:9383998) UniProt PMID:9383998 NCBI chr11:45,801,504...45,837,357
Ensembl chr11:46,293,717...46,329,759
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869) BHF-UCL PMID:7592869 NCBI chr20:1,519,330...1,548,473 JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in ISO (PMID:7592869) BHF-UCL PMID:7592869 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082
JBrowse link
G MASTL microtubule associated serine/threonine kinase like involved_in ISO (PMID:20538976) UniProt PMID:20538976 NCBI chr10:27,264,475...27,296,085
Ensembl chr10:27,626,892...27,658,180
JBrowse link
G PPIA peptidylprolyl isomerase A ISO RGD PMID:19832699 RGD:7247324 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (PMID:11564868) ParkinsonsUK-UCL PMID:11564868 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B involved_in ISO (PMID:10807923) CAFA PMID:10807923 NCBI chr17:17,652,216...17,662,085
Ensembl chr17:17,868,965...17,878,120
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10585469 PMID:12016225 RGD:625568 RGD:9999389 NCBI chr17:44,224,007...44,240,906
Ensembl chr17:49,098,089...49,126,932
JBrowse link
G PPP4R4 protein phosphatase 4 regulatory subunit 4 acts_upstream_of_or_within ISO (PMID:18715871) MGI PMID:18715871 NCBI chr14:74,806,877...74,912,209
Ensembl chr14:94,139,654...94,244,712
JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) HGNC-UCL PMID:16916641 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G RGN regucalcin ISO RGD PMID:10922512 RGD:9590172 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 involved_in ISO (PMID:24709986) UniProt PMID:24709986 NCBI chr 7:67,973,316...68,024,986
Ensembl chr 7:82,446,562...82,497,769
JBrowse link
G TIPRL TOR signaling pathway regulator involved_in ISO (PMID:17384681) UniProt PMID:17384681 NCBI chr 1:143,666,013...143,689,490
Ensembl chr 1:147,391,890...147,415,425
JBrowse link
negative regulation of phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE2 ankyrin repeat and LEM domain containing 2 involved_in ISO (PMID:22770216) UniProt PMID:22770216 NCBI chr12:130,091,476...130,123,533
Ensembl chr12:134,805,830...134,835,140
JBrowse link
G ATXN1 ataxin 1 acts_upstream_of_or_within ISO (MGI:3774689|PMID:18216249) MGI PMID:18216249 MGI:3774689 NCBI chr 6:16,155,049...16,952,827
Ensembl chr 6:16,526,563...16,548,566
JBrowse link
G ATXN7 ataxin 7 acts_upstream_of_or_within ISO (MGI:3774689|PMID:18216249) MGI PMID:18216249 MGI:3774689 NCBI chr 3:63,766,480...63,906,913
Ensembl chr 3:65,194,703...65,280,879
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:19170105)
(MGI:3852291|PMID:19170105)
UniProt PMID:19170105 MGI:3852291 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:10208428), (PMID:8259215) BHF-UCL PMID:8259215 PMID:10208428 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B involved_in ISO (PMID:8078588) BHF-UCL PMID:8078588 NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr 1:50,214,767...50,221,465
Ensembl chr 1:51,704,528...51,718,374
JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr19:10,118,302...10,120,957 JBrowse link
G DYNLL1 dynein light chain LC8-type 1 involved_in ISO (PMID:18579519) UniProt PMID:18579519 NCBI chr12:118,078,401...118,080,822
Ensembl chr12:121,452,118...121,454,550
JBrowse link
G GRB10 growth factor receptor bound protein 10 involved_in ISO (MGI:3847873|PMID:15664450) BHF-UCL PMID:15664450 MGI:3847873 NCBI chr 7:51,230,945...51,434,560
Ensembl chr 7:51,474,166...51,666,638
JBrowse link
G PRKRIP1 PRKR interacting protein 1 acts_upstream_of_or_within ISO (MGI:2665232|PMID:12679338) MGI PMID:12679338 MGI:2665232 NCBI chr 7:94,515,712...94,567,066
Ensembl chr13:24,723,062...24,734,122
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (MGI:6356246|PMID:30115939) UniProt PMID:30115939 MGI:6356246 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:17612497)
(MGI:5297784|PMID:17612497)
UniProt PMID:17612497 MGI:5297784 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) BHF-UCL PMID:19100238 MGI:3831067 NCBI chr 4:56,442,773...56,491,148
Ensembl chr 4:62,836,288...62,882,570
JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO (MGI:6356246|PMID:30115939) UniProt PMID:30115939 MGI:6356246 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545
JBrowse link
negative regulation of protein autophosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:12070119) UniProt PMID:12070119 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G ENG endoglin involved_in ISO (PMID:12015308) BHF-UCL PMID:12015308 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:11289049) BHF-UCL PMID:11289049 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO (PMID:18046415) UniProt PMID:18046415 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G GFRA2 GDNF family receptor alpha 2 ISO RGD PMID:9608533 RGD:632689 NCBI chr 8:20,935,512...21,033,571
Ensembl chr 8:17,878,102...17,974,457
JBrowse link
G IMPACT impact RWD domain protein involved_in ISO (MGI:5576818|PMID:24333428)
(MGI:5494763|PMID:23447528)
UniProt PMID:23447528 PMID:24333428 MGI:5494763 MGI:5576818 NCBI chr18:17,678,297...17,720,348
Ensembl chr18:21,299,213...21,322,868
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:3662941|PMID:16916642) MGI PMID:16916642 MGI:3662941 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G NLRP12 NLR family pyrin domain containing 12 involved_in ISO (PMID:16203735) HGNC-UCL PMID:16203735 NCBI chr19:50,735,124...50,765,556
Ensembl chr19:59,582,005...59,614,436
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277) MGI PMID:7499277 PMID:8175795 MGI:65996 MGI:77358 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO PMID:18216281 ARUK-UCL PMID:18216281 RGD:13461749 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545
JBrowse link
negative regulation of protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO NFATc3 RGD PMID:19358331 RGD:2312604 NCBI chr17:51,162,993...51,199,202
Ensembl chr17:56,023,381...56,058,744
JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in ISO (MGI:4457251|PMID:17438131), (MGI:4457259|PMID:9792806) UniProt PMID:9792806 PMID:17438131 MGI:4457251 MGI:4457259 NCBI chr  X:59,401,426...59,434,363
Ensembl chr  X:69,460,734...69,493,616
JBrowse link
G MFHAS1 malignant fibrous histiocytoma amplified sequence 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (PMID:11564868) ParkinsonsUK-UCL PMID:11564868 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in ISO (PMID:21466834) GO_Central PMID:21466834 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) HGNC-UCL PMID:16916641 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta involved_in ISO (PMID:17255105) BHF-UCL PMID:17255105 NCBI chr20:41,216,071...41,238,893
Ensembl chr20:42,309,155...42,331,695
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon acts_upstream_of_or_within ISO (MGI:2665158|PMID:12796778) MGI PMID:12796778 MGI:2665158 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189
JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:9373175)
PMID:8524413
BHF-UCL PMID:8524413 PMID:9373175 RGD:8554844 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G AKT1S1 AKT1 substrate 1 involved_in ISO (PMID:17386266) UniProt PMID:17386266 NCBI chr19:46,882,073...46,890,404
Ensembl chr19:55,797,927...55,806,256
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 involved_in ISO (PMID:18305109) UniProt PMID:18305109 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600
JBrowse link
G CAV3 caveolin 3 acts_upstream_of_or_within ISO (MGI:2682500|PMID:14600260) MGI PMID:14600260 MGI:2682500 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:15582998) BHF-UCL PMID:15582998 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:5478702|PMID:22496641) UniProt PMID:22496641 MGI:5478702 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G CEP43 centrosomal protein 43 involved_in ISO (PMID:17888034) UniProt PMID:17888034 NCBI chr 6:164,969,391...165,011,935
Ensembl chr 6:169,945,218...169,988,027
JBrowse link
G CEP85 centrosomal protein 85 involved_in ISO (PMID:26220856) UniProt PMID:26220856 NCBI chr 1:25,495,228...25,539,857
Ensembl chr 1:26,562,744...26,607,852
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G DBNDD2 dysbindin domain containing 2 involved_in ISO (PMID:16618118) UniProt PMID:16618118 NCBI chr20:41,738,913...41,743,520
Ensembl chr20:42,829,178...42,833,333
JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein involved_in ISO (PMID:19446321) UniProt PMID:19446321 NCBI chr 8:116,563,935...116,743,843
Ensembl chr 8:119,311,942...119,492,127
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:15601829) UniProt PMID:15601829 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786
JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527
JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266
JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in ISO (PMID:10330181) BHF-UCL PMID:10330181 NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008
JBrowse link
G EPHA1 EPH receptor A1 involved_in ISO (PMID:19118217) UniProt PMID:19118217 NCBI chr 7:135,385,894...135,403,632
Ensembl chr 7:147,875,363...147,892,745
JBrowse link
G FABP4 fatty acid binding protein 4 acts_upstream_of_or_within ISO (MGI:3578695|PMID:15684432) MGI PMID:15684432 MGI:3578695 NCBI chr 8:78,001,476...78,006,006
Ensembl chr 8:79,624,899...79,630,168
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958
JBrowse link
G GNAQ G protein subunit alpha q involved_in ISO (PMID:20399743) BHF-UCL PMID:20399743 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849
JBrowse link
G GSKIP GSK3B interacting protein involved_in ISO (PMID:16981698) UniProt PMID:16981698 NCBI chr14:76,993,055...77,017,142
Ensembl chr14:96,329,936...96,339,378
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD
BHF-UCL
PMID:16636664 PMID:21668448 RGD:10401931 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 involved_in ISO (MGI:3581090|PMID:15731106) BHF-UCL PMID:15731106 MGI:3581090 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984
JBrowse link
G IL6 interleukin 6 ISO Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ILK integrin linked kinase ISO GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155
JBrowse link
G LRP6 LDL receptor related protein 6 involved_in ISO (PMID:16365045) BHF-UCL PMID:16365045 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G MLLT1 MLLT1 super elongation complex subunit acts_upstream_of_or_within ISO (MGI:1891804|PMID:11007757) MGI PMID:11007757 MGI:1891804 NCBI chr19:5,231,481...5,301,160
Ensembl chr19:6,156,365...6,216,779
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:3689489|PMID:17053831)
(MGI:3655425|PMID:16835260)
MGI PMID:16835260 PMID:17053831 MGI:3655425 MGI:3689489 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NF2 neurofibromin 2 acts_upstream_of_or_within ISO (MGI:2679135|PMID:14580336)
(MGI:3613261|PMID:16405865)
MGI PMID:14580336 PMID:16405865 MGI:2679135 MGI:3613261 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) ParkinsonsUK-UCL PMID:15983381 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:10751438 RGD:1579763 NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:9373175) BHF-UCL PMID:9373175 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (MGI:894256|PMID:9218452) MGI PMID:9218452 MGI:894256 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673
JBrowse link
G PKIG cAMP-dependent protein kinase inhibitor gamma acts_upstream_of_or_within ISO (MGI:894256|PMID:9218452) MGI PMID:9218452 MGI:894256 NCBI chr20:40,861,694...40,949,756
Ensembl chr20:42,039,676...42,049,064
JBrowse link
G PKN1 protein kinase N1 acts_upstream_of_or_within ISO (MGI:5467878|PMID:23223530) MGI PMID:23223530 MGI:5467878 NCBI chr19:13,996,454...14,035,272
Ensembl chr19:14,846,463...14,879,205
JBrowse link
G PLEC plectin involved_in ISO (MGI:2386377|PMID:12200133) MGI PMID:12200133 MGI:2386377 NCBI chr 8:140,681,252...140,742,753
Ensembl chr 8:143,674,696...143,712,433
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E involved_in ISO (PMID:11864573) UniProt PMID:11864573 NCBI chr17:52,832,291...53,057,157
Ensembl chr17:57,874,629...57,903,205
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:11864573) UniProt