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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of steroid metabolic process
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Accession:GO:0019218 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: regulation of steroid metabolism

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regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:24201375) ARUK-UCL PMID:24201375 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:22737085) MGI PMID:22737085 NCBI chrNW_004624741:22,645,580...22,649,722
Ensembl chrNW_004624741:22,645,519...22,649,854 		JBrowse link
G Rora RAR related orphan receptor A involved_in ISO (PMID:17666523) UniProt PMID:17666523 NCBI chrNW_004624781:11,014,185...11,688,558
Ensembl chrNW_004624781:11,014,286...11,679,678 		JBrowse link
G Rorc RAR related orphan receptor C involved_in ISO (PMID:17666523) UniProt PMID:17666523 NCBI chrNW_004624772:19,478,403...19,501,184
Ensembl chrNW_004624772:19,477,093...19,501,169 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624766:4,042,307...4,085,613
Ensembl chrNW_004624766:4,041,816...4,085,209 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO PMID:19342457
(PMID:19342457)		 UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004624761:12,464,243...12,495,294 JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16959810) UniProt PMID:16959810 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 ISO (PMID:12815072)
(PMID:23747249)		 UniProt
MGI		 PMID:12815072 PMID:23747249 NCBI chrNW_004624767:17,434,501...17,439,351
Ensembl chrNW_004624767:17,432,358...17,438,173 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chrNW_004624796:8,383,901...9,074,860
Ensembl chrNW_004624796:8,384,081...9,074,878 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) BHF-UCL PMID:16488887 NCBI chrNW_004624771:19,188,543...19,238,621
Ensembl chrNW_004624771:19,196,366...19,233,338 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Chlsn cholesin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:26,552,102...26,671,059
Ensembl chrNW_004624740:26,549,264...26,662,409 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624737:11,977,397...12,018,437
Ensembl chrNW_004624737:11,977,397...12,018,438 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624780:5,844,473...5,861,493
Ensembl chrNW_004624780:5,843,141...5,862,039 		JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chrNW_004624800:2,533,010...2,543,754
Ensembl chrNW_004624800:2,534,967...2,543,075 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:39,649...41,241 JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624766:4,042,307...4,085,613
Ensembl chrNW_004624766:4,041,816...4,085,209 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004624761:12,464,243...12,495,294 JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004624756:4,585,542...4,593,285 JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO (PMID:17234593) MGI PMID:17234593 NCBI chrNW_004624772:12,099,523...12,127,437
Ensembl chrNW_004624772:12,099,435...12,127,737 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004624756:4,585,542...4,593,285 JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chrNW_004624943:483,230...505,678
Ensembl chrNW_004624943:484,942...486,390 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624800:2,533,010...2,543,754
Ensembl chrNW_004624800:2,534,967...2,543,075 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624732:27,089,776...27,110,170
Ensembl chrNW_004624732:27,087,674...27,104,181 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of ISO (PMID:9384387) HGNC-UCL PMID:9384387 NCBI chrNW_004624762:25,759,976...25,769,543
Ensembl chrNW_004624762:25,764,452...25,769,487 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:15317892), (PMID:18182450) UniProt PMID:15317892 PMID:18182450 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within ISO (PMID:21187369) MGI PMID:21187369 NCBI chrNW_004624869:1,695,362...1,936,097
Ensembl chrNW_004624869:1,695,480...1,936,048 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) UniProt PMID:18818293 NCBI chrNW_004624832:4,816,383...4,820,082
Ensembl chrNW_004624832:4,816,277...4,819,740 		JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in ISO (PMID:25264202) UniProt PMID:25264202 NCBI chrNW_004624749:17,579,690...17,595,111
Ensembl chrNW_004624749:17,579,661...17,593,150 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:12949260) UniProt PMID:12949260 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chrNW_004624790:5,509,541...5,515,240
Ensembl chrNW_004624790:5,509,311...5,515,266 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278 PMID:19502595 NCBI chrNW_004624735:6,594,564...6,598,288
Ensembl chrNW_004624735:6,594,695...6,598,757 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004624759:15,459,436...15,520,225
Ensembl chrNW_004624759:15,459,288...15,520,924 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1d1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:3,102,424...3,109,497
Ensembl chrNW_004624795:3,102,439...3,109,497 		JBrowse link
G Star steroidogenic acute regulatory protein involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004624780:5,494,430...5,501,063
Ensembl chrNW_004624780:5,493,786...5,502,030 		JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004624743:29,278,327...29,298,050
Ensembl chrNW_004624743:29,282,558...29,293,854 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) BHF-UCL PMID:17916878 NCBI chrNW_004624745:28,137,140...28,188,670
Ensembl chrNW_004624745:28,104,744...28,188,704 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in ISO (PMID:17916878) BHF-UCL PMID:17916878 NCBI chrNW_004624784:14,529,957...14,545,125
Ensembl chrNW_004624784:14,529,976...14,545,246 		JBrowse link
G Fdps farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chrNW_004624885:942,998...949,529
Ensembl chrNW_004624885:943,571...949,528 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO (PMID:19229075) BHF-UCL PMID:19229075 NCBI chrNW_004624774:1,779,168...1,867,321
Ensembl chrNW_004624774:1,779,170...1,867,300 		JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chrNW_004624739:28,995,173...29,074,354
Ensembl chrNW_004624739:28,995,179...29,073,813 		JBrowse link
G LOC101701685 cholesterol 7-alpha-monooxygenase involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chrNW_004624744:33,563,564...33,619,851
Ensembl chrNW_004624744:33,612,901...33,619,869 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757 		JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624829:6,795,563...6,839,416
Ensembl chrNW_004624829:6,795,528...6,834,604 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chrNW_004624758:13,542,467...13,545,106
Ensembl chrNW_004624758:13,536,493...13,545,599 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chrNW_004624757:12,140,041...12,303,568
Ensembl chrNW_004624757:12,138,681...12,159,661 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chrNW_004624901:1,319,426...1,336,848
Ensembl chrNW_004624901:1,319,062...1,336,744 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) UniProt PMID:33942715 NCBI chrNW_004624785:15,738,231...15,845,051
Ensembl chrNW_004624785:15,739,187...15,845,024 		JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chrNW_004624730:73,926,978...73,975,337
Ensembl chrNW_004624730:73,927,010...73,975,337 		JBrowse link
G Scp2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chrNW_004624859:106,405...252,870
Ensembl chrNW_004624859:107,258...252,756 		JBrowse link
G Sec14l2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chrNW_004624747:6,719,549...6,742,794
Ensembl chrNW_004624747:6,719,498...6,742,794 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12177166), (PMID:32322062)
(PMID:8833906), (PMID:9062341)
(PMID:9329978)
(PMID:16046411)		 UniProt
MGI		 PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... NCBI chrNW_004624849:3,602,103...3,623,922
Ensembl chrNW_004624849:3,602,261...3,623,465 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:12177166), (PMID:32322062), (PMID:38503280)
(PMID:33942715), (PMID:34021134)		 UniProt PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 NCBI chrNW_004624752:6,815,075...6,871,674
Ensembl chrNW_004624752:6,816,468...6,871,567 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577 		JBrowse link
G Agtr1 angiotensin II receptor type 1 acts_upstream_of ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chrNW_004624730:25,964,848...26,006,468
Ensembl chrNW_004624730:25,964,811...26,006,463 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758) BHF-UCL PMID:15654758 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004624743:29,278,327...29,298,050
Ensembl chrNW_004624743:29,282,558...29,293,854 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr5a2 nuclear receptor subfamily 5 group A member 2 involved_in ISO (PMID:16923850), (PMID:17670946) UniProt PMID:16923850 PMID:17670946 NCBI chrNW_004624798:356,953...494,877 JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chrNW_004624755:7,826,219...8,460,746
Ensembl chrNW_004624755:8,375,596...8,465,297 		JBrowse link
positive regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO RGD PMID:18582595 RGD:2316120 NCBI chrNW_004624877:4,421,307...4,447,574
Ensembl chrNW_004624877:4,422,022...4,447,460 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624799:7,249,502...7,265,662
Ensembl chrNW_004624799:7,249,586...7,265,999 		JBrowse link
G Fshb follicle stimulating hormone subunit beta involved_in ISO (PMID:2494176) UniProt PMID:2494176 NCBI chrNW_004624766:19,328,730...19,332,385
Ensembl chrNW_004624766:19,329,371...19,331,267 		JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:16595703 RGD:2311095 NCBI chrNW_004624749:12,795,967...12,805,658
Ensembl chrNW_004624749:12,795,946...12,805,154 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO PMID:1703300 UniProt
RGD		 PMID:1703300 PMID:3030719 RGD:8554045 RGD:9999179 NCBI chrNW_004624859:106,405...252,870
Ensembl chrNW_004624859:107,258...252,756 		JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin like growth factor 1 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Igf1r insulin like growth factor 1 receptor involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004624768:5,396,027...5,688,435
Ensembl chrNW_004624768:5,396,156...5,681,809 		JBrowse link
G Igf2 insulin like growth factor 2 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004624767:14,969,977...14,997,577
Ensembl chrNW_004624767:14,969,866...14,979,026 		JBrowse link
G LOC101712555 NADPH--cytochrome P450 reductase ISO hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chrNW_004624740:14,739,458...14,790,736
Ensembl chrNW_004624740:14,733,427...14,791,065 		JBrowse link
G LOC101726496 steroid 17-alpha-hydroxylase/17,20 lyase ISO androstenedione RGD PMID:19615041 RGD:4888510 NCBI chrNW_004624831:2,155,851...2,166,621
Ensembl chrNW_004624831:2,157,048...2,166,539 		JBrowse link
positive regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chrNW_004624859:106,405...252,870
Ensembl chrNW_004624859:107,258...252,756 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chrNW_004624730:72,228,912...72,242,636
Ensembl chrNW_004624730:72,228,189...72,244,332 		JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO (PMID:17122062) MGI PMID:17122062 NCBI chrNW_004624754:10,152,635...10,885,239
Ensembl chrNW_004624754:10,153,809...10,885,079 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr4 fibroblast growth factor receptor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:12,964,893...12,979,198
Ensembl chrNW_004624733:12,964,746...12,976,732 		JBrowse link
G LOC101701685 cholesterol 7-alpha-monooxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624744:33,563,564...33,619,851
Ensembl chrNW_004624744:33,612,901...33,619,869 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20375098) UniProt PMID:20375098 NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946 		JBrowse link
regulation of bile acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 involved_in ISO (PMID:23764895) UniProt PMID:23764895 NCBI chrNW_004624787:6,653,849...6,733,058
Ensembl chrNW_004624787:6,650,772...6,733,195 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chrNW_004624761:14,733,912...14,831,428 JBrowse link
G Pank2 pantothenate kinase 2 involved_in ISO (PMID:22221393) ParkinsonsUK-UCL PMID:22221393 NCBI chrNW_004624741:4,966,136...5,025,465
Ensembl chrNW_004624741:4,966,260...5,007,207 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO (PMID:16455790) MGI PMID:16455790 NCBI chrNW_004624738:3,579,747...3,622,508
Ensembl chrNW_004624738:3,580,033...3,620,192 		JBrowse link
G Aqp8 aquaporin 8 involved_in ISO (PMID:30579780) UniProt PMID:30579780 NCBI chrNW_004624782:10,074,875...10,082,628
Ensembl chrNW_004624782:10,075,062...10,082,076 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chrNW_004624767:16,118,157...16,132,225
Ensembl chrNW_004624767:16,118,052...16,132,834 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) ComplexPortal PMID:24217618 NCBI chrNW_004624737:11,977,397...12,018,437
Ensembl chrNW_004624737:11,977,397...12,018,438 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) ComplexPortal PMID:24217618 NCBI chrNW_004624780:5,844,473...5,861,493
Ensembl chrNW_004624780:5,843,141...5,862,039 		JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:26,585,913...26,603,517
Ensembl chrNW_004624740:26,586,517...26,603,517 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISO (PMID:29395055) UniProt PMID:29395055 NCBI chrNW_004624860:3,611,300...3,642,682
Ensembl chrNW_004624860:3,611,300...3,642,686 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chrNW_004624744:14,227,430...14,245,082
Ensembl chrNW_004624744:14,240,570...14,245,183 		JBrowse link
G Scap SREBF chaperone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16054043) MGI
TreeGrafter		 PMID:16054043 GO_REF:0000118 NCBI chrNW_004624730:73,926,978...73,975,337
Ensembl chrNW_004624730:73,927,010...73,975,337 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) BHF-UCL PMID:16556852 NCBI chrNW_004624745:28,137,140...28,188,670
Ensembl chrNW_004624745:28,104,744...28,188,704 		JBrowse link
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624765:6,018,534...6,050,736 JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624786:9,838,102...9,843,506
Ensembl chrNW_004624786:9,838,227...9,843,332 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:24412220) ARUK-UCL PMID:24412220 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within		 ISO (PMID:20663892) UniProt
MGI		 PMID:20663892 NCBI chrNW_004624775:18,634,671...18,652,476
Ensembl chrNW_004624775:18,638,010...18,652,985 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004624817:1,386,876...1,418,129
Ensembl chrNW_004624817:1,386,764...1,418,300 		JBrowse link
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chrNW_004624755:26,179,099...26,197,764
Ensembl chrNW_004624755:26,179,162...26,189,901 		JBrowse link
G Ephx2 epoxide hydrolase 2 involved_in ISO (PMID:18974052) UniProt PMID:18974052 NCBI chrNW_004624758:22,216,462...22,252,467
Ensembl chrNW_004624758:22,221,314...22,254,813 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:16,132,648...16,155,717
Ensembl chrNW_004624772:16,131,954...16,155,477 		JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO (PMID:29206867) ARUK-UCL PMID:29206867 NCBI chrNW_004624860:3,509,185...3,515,025
Ensembl chrNW_004624860:3,509,397...3,515,352 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:24412220) ARUK-UCL PMID:24412220 NCBI chrNW_004624828:2,999,122...3,021,893
Ensembl chrNW_004624828:2,999,169...3,021,987 		JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chrNW_004624913:1,651,435...1,750,767
Ensembl chrNW_004624913:1,655,386...1,762,094 		JBrowse link
G LOC101703668 tetratricopeptide repeat protein 39B-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624738:20,259,806...20,268,804 JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:7,191,049...7,204,386
Ensembl chrNW_004624734:7,191,010...7,206,020 		JBrowse link
G Thrb thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chrNW_004624788:1,950,888...2,348,895
Ensembl chrNW_004624788:1,950,890...2,349,343 		JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624736:19,304,586...19,480,182
Ensembl chrNW_004624736:19,349,599...19,480,039 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chrNW_004624755:26,179,099...26,197,764
Ensembl chrNW_004624755:26,179,162...26,189,901 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in ISO (PMID:18628520), (PMID:23132696)
(PMID:16356929)		 UniProt PMID:16356929 PMID:18628520 PMID:23132696 NCBI chrNW_004624818:3,025,323...3,052,486
Ensembl chrNW_004624818:3,025,252...3,051,260 		JBrowse link
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3 group C member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632 		JBrowse link
regulation of glucocorticoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal galanin and GMAP prepropeptide ISO RGD PMID:17273801 RGD:1624340 NCBI chrNW_004624767:18,195,288...18,210,634
Ensembl chrNW_004624767:18,204,508...18,210,416 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:11146632) HGNC-UCL PMID:11146632 NCBI chrNW_004624913:1,491,873...1,494,249
Ensembl chrNW_004624913:1,491,991...1,494,249 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chrNW_004624755:26,179,099...26,197,764
Ensembl chrNW_004624755:26,179,162...26,189,901 		JBrowse link
G Egr1 early growth response 1 involved_in ISO (PMID:8703054) UniProt PMID:8703054 NCBI chrNW_004624743:31,247,855...31,251,675
Ensembl chrNW_004624743:31,247,516...31,252,205 		JBrowse link
regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc5 armadillo repeat containing 5 acts_upstream_of_or_within ISO (PMID:28911199) MGI PMID:28911199 NCBI chrNW_004624782:14,461,488...14,468,407
Ensembl chrNW_004624782:14,462,114...14,468,404 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:22261821), (PMID:22927646) UniProt PMID:22261821 PMID:22927646 NCBI chrNW_004624769:21,112,705...21,140,004
Ensembl chrNW_004624769:21,112,851...21,138,831 		JBrowse link
G Ddx20 DEAD-box helicase 20 acts_upstream_of_or_within ISO (PMID:18258677) MGI PMID:18258677 NCBI chrNW_004624772:7,450,898...7,475,686
Ensembl chrNW_004624772:7,450,616...7,476,054 		JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624816:3,096,137...3,100,882
Ensembl chrNW_004624816:3,095,849...3,104,228 		JBrowse link
G Igfbp7 insulin like growth factor binding protein 7 ISO RGD PMID:17522074 RGD:1626541 NCBI chrNW_004624761:12,318,571...12,387,489
Ensembl chrNW_004624761:12,318,006...12,387,582 		JBrowse link
G Lep leptin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:17241129 RGD:1600071 NCBI chrNW_004624738:29,902,364...29,967,384
Ensembl chrNW_004624738:29,903,571...29,966,915 		JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO (PMID:17495005) MGI PMID:17495005 NCBI chrNW_004624767:21,606,059...21,621,831
Ensembl chrNW_004624767:21,606,065...21,621,830 		JBrowse link
G Star steroidogenic acute regulatory protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7961770) MGI
TreeGrafter		 PMID:7961770 GO_REF:0000118 NCBI chrNW_004624780:5,494,430...5,501,063
Ensembl chrNW_004624780:5,493,786...5,502,030 		JBrowse link
G Tspo translocator protein ISO RGD PMID:9974124 RGD:2317173 NCBI chrNW_004624752:5,814,784...5,820,250
Ensembl chrNW_004624752:5,814,784...5,820,141 		JBrowse link
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhcgr luteinizing hormone/choriogonadotropin receptor acts_upstream_of_or_within ISO (PMID:11145748) MGI PMID:11145748 NCBI chrNW_004624738:29,902,364...29,967,384
Ensembl chrNW_004624738:29,903,571...29,966,915 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chrNW_004624885:1,526,625...1,528,235
Ensembl chrNW_004624885:1,527,538...1,528,109 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chrNW_004624765:8,374,160...8,436,969 JBrowse link
G Gprc6a G protein-coupled receptor class C group 6 member A involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chrNW_004624798:12,865,834...12,888,598
Ensembl chrNW_004624798:12,865,731...12,888,685 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chrNW_004624791:11,334,146...12,656,480
Ensembl chrNW_004624791:11,338,510...12,654,812 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17650
    cellular process 17226
      metabolic process 11002
        primary metabolic process 9835
          lipid metabolic process 1270
            steroid metabolic process 287
              regulation of steroid metabolic process 113
                negative regulation of steroid metabolic process + 27
                positive regulation of steroid metabolic process + 40
                regulation of aldosterone metabolic process + 9
                regulation of bile acid metabolic process + 12
                regulation of cholesterol metabolic process + 48
                regulation of ecdysteroid metabolic process + 0
                regulation of glucocorticoid metabolic process + 12
                regulation of steroid biosynthetic process + 87
Path 2
Term Annotations click to browse term
  biological_process 17650
    biological regulation 11838
      regulation of biological process 11481
        regulation of cellular process 11153
          regulation of metabolic process 5927
            regulation of primary metabolic process 4962
              regulation of lipid metabolic process 347
                regulation of steroid metabolic process 113
                  negative regulation of steroid metabolic process + 27
                  positive regulation of steroid metabolic process + 40
                  regulation of aldosterone metabolic process + 9
                  regulation of bile acid metabolic process + 12
                  regulation of cholesterol metabolic process + 48
                  regulation of ecdysteroid metabolic process + 0
                  regulation of glucocorticoid metabolic process + 12
                  regulation of steroid biosynthetic process + 87
paths to the root