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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of steroid metabolic process
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Accession:GO:0019218 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: regulation of steroid metabolism

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regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24201375) ARUK-UCL
Ensembl		 PMID:24201375 GO_REF:0000107 NCBI chr12:1,161,340...1,183,807
Ensembl chr12:1,162,865...1,183,113 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:22737085) MGI PMID:22737085 NCBI chr 2:51,577,127...51,585,168
Ensembl chr 2:51,577,833...51,580,297 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15471942) MGI
Ensembl		 PMID:15471942 GO_REF:0000107 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,263,889...23,002,224
Ensembl chr26:22,812,445...22,993,021 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (PMID:17666523) UniProt PMID:17666523 NCBI chr20:11,854,911...11,880,221
Ensembl chr20:11,855,005...11,879,717 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15471942) MGI PMID:15471942 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,696,379...15,819,454
Ensembl chr17:15,696,580...15,819,564 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:52,823,415...52,868,804
Ensembl chr 1:52,824,176...52,868,885 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,749,312...11,776,103
Ensembl chr 7:11,749,168...11,773,340 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23747249) MGI
Ensembl		 PMID:23747249 GO_REF:0000107 NCBI chr 1:4,852,289...4,860,139
Ensembl chr 1:4,854,363...4,859,102 		JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr 9:18,964,693...19,640,356 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:15,533,546...15,592,834
Ensembl chr25:15,538,964...15,587,059 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr20:40,771,238...40,786,008
Ensembl chr20:40,776,816...40,783,717 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G CHLSN cholesin involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:20,452,734...20,575,087
Ensembl chr28:20,452,748...20,575,450 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:93,181,320...93,217,967
Ensembl chr 9:93,181,319...93,217,034 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:35,771,541...35,789,848
Ensembl chr 8:35,771,580...35,789,345 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:82,632,151...82,634,101
Ensembl chr 9:82,633,004...82,633,819 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,696,379...15,819,454
Ensembl chr17:15,696,580...15,819,564 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:52,823,415...52,868,804
Ensembl chr 1:52,824,176...52,868,885 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,749,312...11,776,103
Ensembl chr 7:11,749,168...11,773,340 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17234593) Ensembl
MGI		 PMID:17234593 GO_REF:0000107 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,696,379...15,819,454
Ensembl chr17:15,696,580...15,819,564 		JBrowse link
G HRH1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chr22:47,187,156...47,298,761
Ensembl chr22:47,295,011...47,296,471 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr10:12,198,390...12,219,002
Ensembl chr10:12,196,990...12,219,023 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:9384387) HGNC-UCL
Ensembl		 PMID:9384387 GO_REF:0000107 NCBI chr  X:28,707,698...28,713,158
Ensembl chr  X:28,707,699...28,712,708 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE8B phosphodiesterase 8B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21187369) Ensembl
MGI		 PMID:21187369 GO_REF:0000107 NCBI chr 4:71,425,722...71,668,747
Ensembl chr 4:71,456,017...71,668,437 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr12:1,161,340...1,183,807
Ensembl chr12:1,162,865...1,183,113 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) UniProt PMID:18818293 NCBI chr 6:42,544,459...42,555,653
Ensembl chr 6:42,547,593...42,555,566 		JBrowse link
G GGCX gamma-glutamyl carboxylase involved_in ISO (PMID:25264202) UniProt PMID:25264202 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:13,988,059...13,993,780
Ensembl chr 2:13,988,024...13,993,746 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,043,381...45,047,054
Ensembl chr 8:45,043,393...45,046,978 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 4:38,171,320...38,224,275
Ensembl chr 4:38,173,026...38,224,231 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,078,990...66,086,927
Ensembl chr16:66,079,089...66,090,685 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:14,842,152...14,854,675
Ensembl chr23:14,842,286...14,854,702 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) BHF-UCL PMID:17916878 NCBI chr 2:86,098,818...86,176,101
Ensembl chr 2:86,099,414...86,179,949 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,522,773...110,537,747
Ensembl chr 1:110,524,900...110,537,735 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,475,801...54,489,329
Ensembl chr 8:54,477,105...54,485,649 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr20:8,514,311...8,526,363 JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:45,220,827...45,328,387
Ensembl chr23:45,220,800...45,328,328 		JBrowse link
G GNAI1 G protein subunit alpha i1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:68,687,809...68,770,415
Ensembl chr21:68,687,307...68,770,360 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:20,319,731...20,364,603
Ensembl chr  X:20,319,807...20,361,847 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr 7:109,774,700...109,794,543
Ensembl chr 7:109,774,918...109,776,905 		JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:27,358,443...27,385,612
Ensembl chr 7:27,367,059...27,385,568 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:12,727,643...12,758,915 JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) UniProt PMID:33942715 NCBI chr13:91,045,167...91,206,190
Ensembl chr13:91,045,209...91,208,471 		JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:8,821,809...8,887,538
Ensembl chr22:8,818,980...8,850,202 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr19:13,276,712...13,302,737
Ensembl chr19:13,276,913...13,305,003 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16046411)
(PMID:9329978)		 Ensembl
MGI		 PMID:9329978 PMID:16046411 GO_REF:0000107 NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:24,364,725...24,439,851
Ensembl chr19:24,364,911...24,440,014 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G LOC103233018 liver carboxylesterase 1 involved_in ISO (PMID:16971496) UniProt PMID:16971496 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:14,842,152...14,854,675
Ensembl chr23:14,842,286...14,854,702 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103230356 uncharacterized LOC103230356 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:29,230,358...29,380,617
Ensembl chr25:29,233,558...29,379,922 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582 		JBrowse link
positive regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO RGD PMID:18582595 RGD:2316120 NCBI chr16:15,682,669...15,712,079
Ensembl chr16:15,683,077...15,711,858 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093 		JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:34,943,544...34,947,796
Ensembl chr 1:34,943,568...34,946,863 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:16595703 RGD:2311095 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611 		JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO PMID:1703300 UniProt
RGD		 PMID:1703300 PMID:3030719 RGD:8554045 RGD:9999179 NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835 		JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO androstenedione RGD PMID:19615041 RGD:4888510 NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G LOC103246654 NADPH--cytochrome P450 reductase ISO hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chr28:10,145,070...10,230,836
Ensembl chr28:10,197,503...10,230,468 		JBrowse link
positive regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:1690216) BHF-UCL PMID:1690216
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:5,057,687...5,073,596
Ensembl chr15:5,057,900...5,073,184 		JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO (PMID:17122062) MGI PMID:17122062 NCBI chr 9:53,727,790...54,557,252
Ensembl chr 9:54,182,910...54,554,716 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,475,801...54,489,329
Ensembl chr 8:54,477,105...54,485,649 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456 		JBrowse link
G LOC103233018 liver carboxylesterase 1 involved_in ISO (PMID:18599737) UniProt PMID:18599737 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867 		JBrowse link
regulation of bile acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:54,458,283...54,575,943
Ensembl chr10:54,459,377...54,575,059 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr 7:13,808,104...13,891,003
Ensembl chr 7:13,808,037...13,890,976 		JBrowse link
G PANK2 pantothenate kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,577,859...34,612,258
Ensembl chr 2:34,578,207...34,611,987 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr12:1,161,340...1,183,807
Ensembl chr12:1,162,865...1,183,113 		JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16455790) Ensembl
MGI		 PMID:16455790 GO_REF:0000107 NCBI chr14:86,624,209...86,669,175
Ensembl chr14:86,624,332...86,668,704 		JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:22,928,230...22,940,814
Ensembl chr 5:22,928,350...22,940,856 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr 1:3,243,263...3,257,332
Ensembl chr 1:3,243,313...3,257,487 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:93,181,320...93,217,967
Ensembl chr 9:93,181,319...93,217,034 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:35,771,541...35,789,848
Ensembl chr 8:35,771,580...35,789,345 		JBrowse link
G GPR146 G protein-coupled receptor 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:20,522,155...20,538,402
Ensembl chr28:20,522,899...20,523,900 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,009,911...7,051,391
Ensembl chr11:7,005,701...7,051,605 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:72,513,975...72,532,399
Ensembl chr 8:72,514,307...72,517,003 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16054043) Ensembl
TreeGrafter
MGI		 PMID:16054043 GO_REF:0000107 GO_REF:0000118 NCBI chr22:8,821,809...8,887,538
Ensembl chr22:8,818,980...8,850,202 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) BHF-UCL PMID:16556852 NCBI chr 2:86,098,818...86,176,101
Ensembl chr 2:86,099,414...86,179,949 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr10:95,886,502...95,925,928
Ensembl chr10:95,887,465...95,925,578 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:6,593,288...6,598,980
Ensembl chr16:6,593,287...6,598,979 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20663892) Ensembl
MGI		 PMID:20663892 GO_REF:0000107 NCBI chr25:68,251,110...68,271,530
Ensembl chr25:68,251,130...68,271,607 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr 1:66,985,413...67,018,058
Ensembl chr 1:66,985,466...67,021,182 		JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583 		JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,873,043...6,880,676
Ensembl chr11:6,874,351...6,880,179 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,062,204...10,091,780
Ensembl chr 6:10,062,790...10,091,377 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chr 5:761,788...857,798
Ensembl chr 5:762,697...866,926 		JBrowse link
G LOC119623289 diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr24:72,273,041...72,285,367
Ensembl chr24:72,273,186...72,285,157 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr15:68,797,410...69,161,256
Ensembl chr15:68,802,078...68,902,292 		JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:64,315,240...64,452,161
Ensembl chr12:64,372,763...64,450,973 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:122,502,084...122,531,214
Ensembl chr20:122,503,687...122,526,074 		JBrowse link
G LOC119623289 diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR3C1 nuclear receptor subfamily 3 group C member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7628695) Ensembl
MGI		 PMID:7628695 GO_REF:0000107 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125 		JBrowse link
regulation of glucocorticoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL galanin and GMAP prepropeptide ISO RGD PMID:17273801 RGD:1624340 NCBI chr 1:5,849,947...5,857,355
Ensembl chr 1:5,849,952...5,857,072 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:599,907...602,549
Ensembl chr 5:599,819...605,567 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583 		JBrowse link
G EGR1 early growth response 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374 		JBrowse link
G LOC119623289 diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107
regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28911199) MGI
Ensembl		 PMID:28911199 GO_REF:0000107 NCBI chr 5:28,159,796...28,167,575
Ensembl chr 5:28,160,617...28,167,672 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:16,151,974...16,181,726
Ensembl chr 8:16,151,247...16,181,155 		JBrowse link
G DDX20 DEAD-box helicase 20 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18258677) Ensembl
MGI		 PMID:18258677 GO_REF:0000107 NCBI chr20:21,842,398...21,869,247
Ensembl chr20:21,839,223...21,853,601 		JBrowse link
G DHH desert hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:17495005) MGI PMID:17495005 NCBI chr11:45,330,593...45,336,958 JBrowse link
G DHH desert hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 Ensembl chr11:45,330,896...45,335,372 JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO RGD PMID:17522074 RGD:1626541 NCBI chr 7:11,617,096...11,694,530 JBrowse link
G LEP leptin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16513828) MGI
Ensembl		 PMID:16513828 GO_REF:0000107 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:17241129 RGD:1600071 NCBI chr14:58,413,334...58,479,124
Ensembl chr14:58,413,993...58,477,987 		JBrowse link
G SF1 splicing factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17495005) MGI
Ensembl		 PMID:17495005 GO_REF:0000107 NCBI chr 1:9,456,524...9,470,920
Ensembl chr 1:9,456,971...9,472,396 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7961770) Ensembl
TreeGrafter
MGI		 PMID:7961770 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583 		JBrowse link
G TSPO translocator protein ISO RGD PMID:9974124 RGD:2317173 NCBI chr19:25,678,602...25,690,556
Ensembl chr19:25,686,981...25,690,768 		JBrowse link
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11145748) Ensembl
MGI		 PMID:11145748 GO_REF:0000107 NCBI chr14:58,413,334...58,479,124
Ensembl chr14:58,413,993...58,477,987 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:5,248,610...5,263,474 JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832 		JBrowse link
G GPRC6A G protein-coupled receptor class C group 6 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:56,994,267...57,028,736
Ensembl chr13:56,995,346...57,028,305 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr 9:78,858,269...80,188,163 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19822
    cellular process 19340
      metabolic process 13127
        primary metabolic process 11556
          lipid metabolic process 1330
            steroid metabolic process 303
              regulation of steroid metabolic process 118
                negative regulation of steroid metabolic process + 28
                positive regulation of steroid metabolic process + 40
                regulation of aldosterone metabolic process + 9
                regulation of bile acid metabolic process + 13
                regulation of cholesterol metabolic process + 48
                regulation of ecdysteroid metabolic process + 0
                regulation of glucocorticoid metabolic process + 13
                regulation of steroid biosynthetic process + 93
Path 2
Term Annotations click to browse term
  biological_process 19822
    biological regulation 12162
      regulation of biological process 11765
        regulation of cellular process 11404
          regulation of metabolic process 6699
            regulation of primary metabolic process 5325
              regulation of lipid metabolic process 372
                regulation of steroid metabolic process 118
                  negative regulation of steroid metabolic process + 28
                  positive regulation of steroid metabolic process + 40
                  regulation of aldosterone metabolic process + 9
                  regulation of bile acid metabolic process + 13
                  regulation of cholesterol metabolic process + 48
                  regulation of ecdysteroid metabolic process + 0
                  regulation of glucocorticoid metabolic process + 13
                  regulation of steroid biosynthetic process + 93
paths to the root