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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of steroid metabolic process
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Accession:GO:0019218 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: regulation of steroid metabolism


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regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:24201375) ARUK-UCL PMID:24201375 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:22737085) MGI PMID:22737085 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:25,315,974...26,026,708
Ensembl chr30:25,325,275...26,026,623 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (PMID:17666523) UniProt PMID:17666523 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISO PMID:19342457
(PMID:19342457)		 UniProt PMID:19342457 RGD:4891166 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 IEA Ensembl GO_REF:0000107 NCBI chr18:48,464,931...48,469,967
Ensembl chr18:48,464,928...48,469,782 		JBrowse link
G LOC608668 MAM and LDL-receptor class A domain-containing protein 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr 2:13,151,316...13,904,122 JBrowse link
G MIR33A microRNA mir-33a involved_in ISO (PMID:23536474) BHF-UCL PMID:23536474 NCBI chr10:23,456,613...23,456,673
Ensembl chr10:23,456,613...23,456,673 		JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,996,282...12,047,693
Ensembl chr 7:11,996,703...12,044,036 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G C6H7orf50 chromosome 6 C7orf50 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,749,123...15,896,429 JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378 		JBrowse link
G MIR185 microRNA mir-185 acts_upstream_of ISO (PMID:24296663)
(PMID:23951060)		 BHF-UCL PMID:23951060 PMID:24296663 NCBI chr26:29,296,014...29,296,069
Ensembl chr26:29,296,004...29,296,079 		JBrowse link
G MIR342 microRNA mir-342 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr 8:68,424,656...68,424,718 JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,725,903...15,736,450
Ensembl chr 6:15,726,076...15,883,451 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in ISO (PMID:29033131) UniProt PMID:29033131 NCBI chr26:38,884,356...38,885,728 JBrowse link
G MIR27A microRNA mir-27a involved_in ISO (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr20:48,620,556...48,620,615
Ensembl chr20:48,620,556...48,620,615 		JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G HRH1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chr20:7,160,903...7,236,147
Ensembl chr20:7,162,393...7,235,869 		JBrowse link
G INSIG1 insulin induced gene 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378 		JBrowse link
G INSIG2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chr19:31,796,984...31,811,556
Ensembl chr19:31,791,710...31,811,386 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of ISO (PMID:9384387) HGNC-UCL PMID:9384387 NCBI chr  X:25,396,527...25,401,587
Ensembl chr  X:25,396,527...25,401,715 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE8B phosphodiesterase 8B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:29,289,867...29,432,557
Ensembl chr 3:29,291,549...29,432,542 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,109,787...107,113,932
Ensembl chr 1:107,109,791...107,113,811 		JBrowse link
G GGCX gamma-glutamyl carboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:39,512,293...39,525,251
Ensembl chr17:39,512,387...39,529,121 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:36,498,343...36,503,623
Ensembl chr24:36,498,062...36,503,628 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278 PMID:19502595 NCBI chr29:1,154,132...1,156,653
Ensembl chr29:1,154,036...1,156,653 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,461,556...22,469,243
Ensembl chr 9:22,461,705...22,469,053 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:1,154,358...1,171,248
Ensembl chr 3:1,154,358...1,170,469 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,707,964...14,720,782
Ensembl chr 5:14,707,960...14,721,240 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 7:42,241,086...42,250,373
Ensembl chr 7:42,241,107...42,250,225 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619 		JBrowse link
G GNAI1 G protein subunit alpha i1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:19,924,381...19,952,956
Ensembl chr18:19,924,235...19,951,244 		JBrowse link
G LOC477539 SEC14-like protein 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr26:23,542,555...23,563,579 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:17,655,295...17,718,960
Ensembl chr  X:17,655,363...17,710,288 		JBrowse link
G MIR96 microRNA mir-96 involved_in
acts_upstream_of		 ISO (PMID:23823476)
(PMID:30460077)		 BHF-UCL PMID:23823476 PMID:30460077 NCBI chr14:7,068,754...7,068,842
Ensembl chr14:7,068,754...7,068,842 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr15:59,580,546...59,587,753
Ensembl chr15:59,580,809...59,583,237 		JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:3,292,034...3,316,914
Ensembl chr32:3,288,645...3,316,965 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) UniProt PMID:33942715 NCBI chr 1:51,800,294...51,956,891
Ensembl chr 1:51,800,309...51,952,714 		JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA Ensembl GO_REF:0000107 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G CES1 carboxylesterase 1 involved_in ISO (PMID:16971496) UniProt PMID:16971496 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:1,154,358...1,171,248
Ensembl chr 3:1,154,358...1,170,469 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR5A2 nuclear receptor subfamily 5 group A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,925,915...3,062,118
Ensembl chr 7:2,927,326...3,062,348 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269 		JBrowse link
positive regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO RGD PMID:18582595 RGD:2316120 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G CGA glycoprotein hormones, alpha polypeptide involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr12:46,610,801...46,629,322
Ensembl chr12:46,610,973...46,636,640 		JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in ISO (PMID:2494176) UniProt PMID:2494176 NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:16595703 RGD:2311095 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO PMID:1703300 RGD
UniProt		 PMID:1703300 PMID:3030719 RGD:8554045 RGD:9999179 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014 		JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO androstenedione RGD PMID:19615041 RGD:4888510 NCBI chr28:15,292,959...15,298,896
Ensembl chr28:15,293,106...15,298,852 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chr 6:7,247,780...7,316,282
Ensembl chr 6:7,263,574...7,316,297 		JBrowse link
positive regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,224,136...17,238,755
Ensembl chr34:17,223,215...17,239,621 		JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within		 ISA
ISO		 (PMID:8973172)
(PMID:17122062)		 AgBase
MGI		 PMID:8973172 PMID:17122062 NCBI chr 4:26,844,250...27,338,271
Ensembl chr 4:26,844,250...27,555,776 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CES1 carboxylesterase 1 involved_in ISO (PMID:18599737) UniProt PMID:18599737 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:36,243,689...36,254,636
Ensembl chr 4:36,244,220...36,252,035 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:20375098) UniProt PMID:20375098 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
regulation of bile acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:13,742,895...13,835,312
Ensembl chr36:13,746,964...13,834,974 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G PANK2 pantothenate kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,461,406...17,475,248
Ensembl chr24:17,463,447...17,490,360 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
G APOB apolipoprotein B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,877,937...15,916,032
Ensembl chr17:15,878,244...15,915,135 		JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:20,984,868...20,992,647
Ensembl chr 6:20,984,908...20,992,524 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202 		JBrowse link
G GPR146 G protein-coupled receptor 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,819,274...15,838,021
Ensembl chr 6:15,824,117...15,825,118 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,028,438...38,068,854
Ensembl chr27:38,028,120...38,068,502 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr29:24,943,563...24,960,834 JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr37:18,028,244...18,073,975
Ensembl chr37:18,017,087...18,073,862 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,189,191...32,194,255
Ensembl chr 5:32,186,502...32,327,990 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator acts_upstream_of_or_within
involved_in		 IEA Ensembl GO_REF:0000107 NCBI chr 4:8,409,039...8,424,776
Ensembl chr 4:8,409,484...8,424,644 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr21:22,833,659...22,850,300
Ensembl chr21:22,834,518...22,851,260 		JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,544,350...91,554,494
Ensembl chr 3:91,544,219...91,554,565 		JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,665,879...57,698,540
Ensembl chr17:57,666,762...57,697,982 		JBrowse link
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,175,928...38,182,473
Ensembl chr27:38,175,931...38,181,763 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chr 6:39,682,229...39,768,311
Ensembl chr 6:39,696,442...39,762,709 		JBrowse link
G SERPINA12 serpin family A member 12 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:63,497,542...63,511,701
Ensembl chr 8:63,497,849...63,512,171 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr23:19,278,650...19,648,547
Ensembl chr23:19,277,493...19,660,283 		JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:35,465,198...35,557,800
Ensembl chr11:35,472,016...35,589,835 		JBrowse link
G TTC39D tetratricopeptide repeat domain 39D involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:30,816,281...30,868,850 JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,544,350...91,554,494
Ensembl chr 3:91,544,219...91,554,565 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:62,548,136...62,577,346
Ensembl chr 5:62,548,221...62,608,964 		JBrowse link
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR3C1 nuclear receptor subfamily 3 group C member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755 		JBrowse link
regulation of glucocorticoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL galanin and GMAP prepropeptide ISO RGD PMID:17273801 RGD:1624340 NCBI chr18:49,240,437...49,246,543
Ensembl chr18:49,240,437...49,246,950 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,544,350...91,554,494
Ensembl chr 3:91,544,219...91,554,565 		JBrowse link
G EGR1 early growth response 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G MIR125A microRNA mir-125a ISO RGD PMID:23045399 RGD:26884342 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G MIR455 microRNA mir-455 ISO RGD PMID:23045399 RGD:26884342 NCBI chr11:68,461,911...68,461,968
Ensembl chr11:68,461,896...68,461,983 		JBrowse link
regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) ISO RGD PMID:4392955 RGD:2303525 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G ARMC5 armadillo repeat containing 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:16,782,732...16,789,490
Ensembl chr 6:16,781,860...16,788,878 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:22261821), (PMID:22927646) UniProt PMID:22261821 PMID:22927646 NCBI chr16:41,297,215...41,335,521
Ensembl chr16:41,297,809...41,323,078 		JBrowse link
G DDX20 DEAD-box helicase 20 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:63,676,146...63,687,503
Ensembl chr17:63,676,452...63,687,506 		JBrowse link
G DHH desert hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:5,490,122...5,497,144
Ensembl chr27:5,490,441...5,494,636 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO RGD PMID:17522074 RGD:1626541 NCBI chr13:49,138,406...49,207,235
Ensembl chr13:49,138,402...49,207,394 		JBrowse link
G LEP leptin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:17241129 RGD:1600071 NCBI chr10:50,540,706...50,594,336
Ensembl chr10:50,541,960...50,598,036 		JBrowse link
G SF1 splicing factor 1 acts_upstream_of_or_within ISO (PMID:17495005) MGI PMID:17495005 NCBI chr18:52,380,058...52,393,833
Ensembl chr18:52,380,211...52,393,048 		JBrowse link
G STAR steroidogenic acute regulatory protein acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:7961770) MGI
GO_Central		 PMID:7961770 GO_REF:0000033 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G TSPO translocator protein ISO RGD PMID:9974124 RGD:2317173 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297 		JBrowse link
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:50,540,706...50,594,336
Ensembl chr10:50,541,960...50,598,036 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) involved_in ISO (PMID:19336506) UniProt PMID:19336506 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G GPRC6A G protein-coupled receptor class C group 6 member A involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chr 1:57,191,210...57,212,008
Ensembl chr 1:57,191,325...57,212,027 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      metabolic process 15400
        primary metabolic process 13972
          lipid metabolic process 1356
            steroid metabolic process 320
              regulation of steroid metabolic process 127
                negative regulation of steroid metabolic process + 34
                positive regulation of steroid metabolic process + 42
                regulation of aldosterone metabolic process + 9
                regulation of bile acid metabolic process + 14
                regulation of cholesterol metabolic process + 56
                regulation of ecdysteroid metabolic process + 0
                regulation of glucocorticoid metabolic process + 12
                regulation of steroid biosynthetic process + 97
Path 2
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological process 12176
        regulation of cellular process 11829
          regulation of metabolic process 6540
            regulation of primary metabolic process 5324
              regulation of lipid metabolic process 390
                regulation of steroid metabolic process 127
                  negative regulation of steroid metabolic process + 34
                  positive regulation of steroid metabolic process + 42
                  regulation of aldosterone metabolic process + 9
                  regulation of bile acid metabolic process + 14
                  regulation of cholesterol metabolic process + 56
                  regulation of ecdysteroid metabolic process + 0
                  regulation of glucocorticoid metabolic process + 12
                  regulation of steroid biosynthetic process + 97
paths to the root