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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of steroid metabolic process
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Accession:GO:0019218 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: regulation of steroid metabolism


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regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24201375) ARUK-UCL
Ensembl		 PMID:24201375 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:22737085) MGI PMID:22737085 NCBI chr20:22,519,942...22,524,262 JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15471942) MGI PMID:15471942 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15471942) Ensembl
MGI		 PMID:15471942 GO_REF:0000107 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,461,553...40,200,118
Ensembl chr15:57,771,735...57,980,460 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (PMID:17666523) UniProt PMID:17666523 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028 		JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr10:19,461,865...19,886,155 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CHLSN cholesin involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chr 7:1,156,770...1,383,223
Ensembl chr 7:1,369,532...1,497,518 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,930,638...85,932,065
Ensembl chr10:89,471,441...89,472,259 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17234593) Ensembl
MGI		 PMID:17234593 GO_REF:0000107 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G HRH1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chr 3:11,074,451...11,199,871
Ensembl chr 3:11,541,294...11,542,757 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:9384387) HGNC-UCL
Ensembl		 PMID:9384387 GO_REF:0000107 NCBI chr  X:22,903,403...22,908,527
Ensembl chr  X:30,459,527...30,464,652 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE8B phosphodiesterase 8B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21187369) Ensembl
MGI		 PMID:21187369 GO_REF:0000107 NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,375,301...46,389,822
Ensembl chr19:55,301,955...55,313,690 		JBrowse link
G GGCX gamma-glutamyl carboxylase involved_in ISO (PMID:25264202) UniProt PMID:25264202 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,188,390...17,196,315
Ensembl chr17:17,409,669...17,417,600 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) BHF-UCL PMID:17916878 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,987,709...114,001,354
Ensembl chr11:117,916,043...117,929,636 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 1:130,653,316...130,665,196
Ensembl chr 1:134,258,968...134,270,237 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001 		JBrowse link
G GNAI1 G protein subunit alpha i1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:72,102,937...72,188,124
Ensembl chr 7:85,812,249...85,851,283 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,470,268...14,529,854
Ensembl chr  X:21,825,780...21,883,550 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597 		JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) UniProt PMID:33942715 NCBI chr 6:161,361,413...161,523,414 JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,314,535...47,379,455
Ensembl chr 3:48,414,012...48,479,845 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr22:11,432,608...11,460,973
Ensembl chr22:29,234,162...29,261,937 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9329978)
(PMID:16046411)		 Ensembl
MGI		 PMID:9329978 PMID:16046411 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR5A2 nuclear receptor subfamily 5 group A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:175,625,140...175,775,955
Ensembl chr 1:179,934,573...180,083,607 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212 		JBrowse link
positive regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO RGD PMID:18582595 RGD:2316120 NCBI chr17:34,849,466...34,880,088 JBrowse link
G CGA glycoprotein hormones, alpha polypeptide involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:84,962,974...84,972,638
Ensembl chr 6:88,236,206...88,247,300 		JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:30,204,193...30,208,410
Ensembl chr11:30,095,486...30,100,167 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:16595703 RGD:2311095 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO PMID:1703300 RGD
UniProt		 PMID:1703300 PMID:3030719 RGD:8554045 RGD:9999179 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO androstenedione RGD PMID:19615041 RGD:4888510 NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890 		JBrowse link
G LOC100971425 somatotropin involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr17:58,010,848...58,013,421
Ensembl chr17:63,103,332...63,105,067 		JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530 		JBrowse link
positive regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049 		JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO (PMID:17122062) MGI PMID:17122062 NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
regulation of bile acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:56,199,434...56,311,773
Ensembl chr2B:173,664,518...173,776,379 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G PANK2 pantothenate kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,924,054...3,959,393
Ensembl chr20:3,723,211...3,757,748 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16455790) Ensembl
MGI		 PMID:16455790 GO_REF:0000107 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:25,458,165...25,469,713 JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G GPR146 G protein-coupled receptor 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:1,202,941...1,217,528
Ensembl chr 7:1,425,358...1,426,359 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,107,925...7,149,982
Ensembl chr12:7,024,015...7,065,945 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:73,508,349...73,526,560
Ensembl chr 8:75,146,255...75,147,172 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16054043) Ensembl
TreeGrafter
MGI		 PMID:16054043 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:47,314,535...47,379,455
Ensembl chr 3:48,414,012...48,479,845 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) BHF-UCL PMID:16556852 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20663892) Ensembl
MGI		 PMID:20663892 GO_REF:0000107 NCBI chr 1:206,527,777...206,549,606
Ensembl chr 1:211,554,553...211,576,484 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854 		JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724 		JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:122,605,677...122,648,325
Ensembl chr 1:112,881,859...112,921,194 		JBrowse link
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,971,854...6,979,214
Ensembl chr12:6,883,280...6,890,692 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 Ensembl chr16:869,449...973,456 JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr14:75,110,414...75,141,569
Ensembl chr14:94,442,931...94,473,779 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960 		JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:14,994,729...15,127,877
Ensembl chr 9:15,502,811...15,633,374 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631 		JBrowse link
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR3C1 nuclear receptor subfamily 3 group C member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7628695) Ensembl
MGI		 PMID:7628695 GO_REF:0000107 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269 		JBrowse link
regulation of glucocorticoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL galanin and GMAP prepropeptide ISO RGD PMID:17273801 RGD:1624340 NCBI chr11:63,770,758...63,777,421
Ensembl chr11:67,075,547...67,081,696 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724 		JBrowse link
G EGR1 early growth response 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260 		JBrowse link
regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 ISO RGD PMID:4392955 RGD:2303525 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G ARMC5 armadillo repeat containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28911199) Ensembl
MGI		 PMID:28911199 GO_REF:0000107 NCBI chr16:23,498,343...23,507,287
Ensembl chr16:31,828,037...31,840,479 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:22261821), (PMID:22927646) UniProt PMID:22261821 PMID:22927646 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G DDX20 DEAD-box helicase 20 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18258677) Ensembl
MGI		 PMID:18258677 GO_REF:0000107 NCBI chr 1:114,402,492...114,432,217
Ensembl chr 1:125,918,392...125,930,197 		JBrowse link
G DHH desert hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17495005) Ensembl
MGI		 PMID:17495005 GO_REF:0000107 NCBI chr12:39,656,046...39,661,439
Ensembl chr12:40,535,740...40,541,123 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO RGD PMID:17522074 RGD:1626541 NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16513828) Ensembl
MGI		 PMID:16513828 GO_REF:0000107 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:17241129 RGD:1600071 NCBI chr2A:48,808,822...48,879,021
Ensembl chr2A:49,729,002...49,798,780 		JBrowse link
G SF1 splicing factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17495005) Ensembl
MGI		 PMID:17495005 GO_REF:0000107 NCBI chr11:60,120,126...60,134,279
Ensembl chr11:63,461,318...63,473,355 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7961770) Ensembl
TreeGrafter
MGI		 PMID:7961770 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
G TSPO translocator protein ISO RGD PMID:9974124 RGD:2317173 NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930 		JBrowse link
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11145748) Ensembl
MGI		 PMID:11145748 GO_REF:0000107 NCBI chr2A:48,808,822...48,879,021
Ensembl chr2A:49,729,002...49,798,780 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G GPRC6A G protein-coupled receptor class C group 6 member A involved_in ISO (PMID:21333348) UniProt PMID:21333348 NCBI chr 6:114,601,360...114,638,286
Ensembl chr 6:118,744,929...118,781,099 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    cellular process 18866
      metabolic process 12815
        primary metabolic process 11228
          lipid metabolic process 1309
            steroid metabolic process 311
              regulation of steroid metabolic process 116
                negative regulation of steroid metabolic process + 29
                positive regulation of steroid metabolic process + 39
                regulation of aldosterone metabolic process + 9
                regulation of bile acid metabolic process + 12
                regulation of cholesterol metabolic process + 46
                regulation of ecdysteroid metabolic process + 0
                regulation of glucocorticoid metabolic process + 12
                regulation of steroid biosynthetic process + 91
Path 2
Term Annotations click to browse term
  biological_process 19312
    biological regulation 11878
      regulation of biological process 11495
        regulation of cellular process 11142
          regulation of metabolic process 6611
            regulation of primary metabolic process 5202
              regulation of lipid metabolic process 359
                regulation of steroid metabolic process 116
                  negative regulation of steroid metabolic process + 29
                  positive regulation of steroid metabolic process + 39
                  regulation of aldosterone metabolic process + 9
                  regulation of bile acid metabolic process + 12
                  regulation of cholesterol metabolic process + 46
                  regulation of ecdysteroid metabolic process + 0
                  regulation of glucocorticoid metabolic process + 12
                  regulation of steroid biosynthetic process + 91
paths to the root