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ONTOLOGY REPORT - ANNOTATIONS


Term:nonribosomal peptide biosynthetic process
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Accession:GO:0019184 term browser browse the term
Definition:The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
Synonyms:exact_synonym: non-ribosomal peptide biosynthesis;   non-ribosomal peptide biosynthetic process;   non-ribosomal peptide formation;   non-ribosomal peptide synthesis;   nonribosomal peptide anabolism;   nonribosomal peptide biosynthesis;   nonribosomal peptide formation;   nonribosomal peptide synthesis
 related_synonym: nonribosomal peptide synthetase



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amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdh aminoadipate-semialdehyde dehydrogenase acts_upstream_of_or_within ISO (MGI:5630050|PMID:24467666) RGD PMID:24467666 MGI:5630050 NCBI chr14:31,255,019...31,281,802
Ensembl chr14:31,255,310...31,281,796
JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
IEA
ISS
MGI:2387010 (MGI:1858542|PMID:10805773), (MGI:3607629|PMID:16081425)
PMID:21873635
GO_REF:0000041
(PMID:10395918), (PMID:12663448), (PMID:8104187), (PMID:9675072)
GO_REF:0000024
RGD
UniProt
PMID:8104187 PMID:9675072 PMID:10395918 PMID:10805773 PMID:12663448 More... GO_REF:0000024 GO_REF:0000041 MGI:1858542 MGI:3607629, RGD:1582661, RGD:13792537 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within
involved_in
IMP
ISO
IEA
IBA
ISS
(MGI:3607629|PMID:16081425)
GO_REF:0000041
PMID:21873635
(PMID:10395918), (PMID:12081989), (PMID:9675072)
GO_REF:0000024
RGD
UniProt
PMID:9675072 PMID:10395918 PMID:12081989 PMID:16081425 PMID:16183645 More... GO_REF:0000024 GO_REF:0000041 MGI:3607629, RGD:1582661, RGD:13792537 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in IEA
ISO
GO_REF:0000043
(MGI:5294309|PMID:12468440)
UniProt
RGD
PMID:12468440 GO_REF:0000043 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ggt5 gamma-glutamyltransferase 5 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:13,043,255...13,071,523 JBrowse link
G Ggt6 gamma-glutamyl transferase 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:57,052,025...57,054,502
Ensembl chr10:57,051,825...57,067,260
JBrowse link
G Ggt7 gamma-glutamyltransferase 7 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:143,978,073...144,004,597
Ensembl chr 3:143,978,082...144,001,492
JBrowse link
G Gss glutathione synthetase involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:10964706 GO_REF:0000041, RGD:1599340 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Hagh hydroxyacyl glutathione hydrolase involved_in IEA
ISO
GO_REF:0000107
(PMID:8550579)
Ensembl
RGD
PMID:8550579 GO_REF:0000107 NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:8703034) RGD PMID:8703034 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:6478075|PMID:12614333) RGD PMID:12614333 MGI:6478075 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc1a2 solute carrier family 1 member 2 involved_in ISO (MGI:6478075|PMID:12614333) RGD PMID:12614333 MGI:6478075 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:5616326|PMID:14978030) RGD PMID:14978030 MGI:5616326 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (MGI:5616326|PMID:14978030) RGD PMID:14978030 MGI:5616326 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (MGI:3588610|PMID:16037214) RGD PMID:16037214 MGI:3588610 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdh2 3-hydroxybutyrate dehydrogenase 2 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4820913|PMID:20550936)
PMID:21873635
UniProt
RGD
PMID:20550936 PMID:21873635 GO_REF:0000024 MGI:4820913, RGD:13792537 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      biosynthetic process 6020
        organic substance biosynthetic process 5918
          organonitrogen compound biosynthetic process 1957
            peptide biosynthetic process 1064
              nonribosomal peptide biosynthetic process 16
                amino acid activation for nonribosomal peptide biosynthetic process + 1
                glutathione biosynthetic process + 14
                siderophore biosynthetic process + 1
                vancomycin biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      nitrogen compound metabolic process 9922
        cellular nitrogen compound metabolic process 6503
          cellular amide metabolic process 1487
            peptide metabolic process 1231
              peptide biosynthetic process 1064
                nonribosomal peptide biosynthetic process 16
                  amino acid activation for nonribosomal peptide biosynthetic process + 1
                  glutathione biosynthetic process + 14
                  siderophore biosynthetic process + 1
                  vancomycin biosynthetic process 0
paths to the root