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ONTOLOGY REPORT - ANNOTATIONS


Term:nonribosomal peptide biosynthetic process
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Accession:GO:0019184 term browser browse the term
Definition:The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
Synonyms:exact_synonym: non-ribosomal peptide biosynthesis;   non-ribosomal peptide biosynthetic process;   non-ribosomal peptide formation;   non-ribosomal peptide synthesis;   nonribosomal peptide anabolism;   nonribosomal peptide biosynthesis;   nonribosomal peptide formation;   nonribosomal peptide synthesis
 related_synonym: nonribosomal peptide synthetase



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amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDH aminoadipate-semialdehyde dehydrogenase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5630050|PMID:24467666) Ensembl
MGI
PMID:24467666 GO_REF:0000107 MGI:5630050 NCBI chr13:48,574,839...48,611,770
Ensembl chr13:48,572,220...48,611,775
JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLC glutamate-cysteine ligase catalytic subunit involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:1858542|PMID:10805773)
(MGI:3607629|PMID:16081425)
GO_Central
MGI
RGD
UniProt
PMID:10805773 PMID:16081425 PMID:16183645 PMID:21873635 GO_REF:0000041 MGI:1858542 MGI:3607629 RGD:1582661 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit acts_upstream_of_or_within
involved_in
ISO (MGI:3607629|PMID:16081425)
(PMID:10395918), (PMID:9675072)
(PMID:12081989)
RGD
MGI
UniProt
PMID:9675072 PMID:10395918 PMID:12081989 PMID:16081425 PMID:16183645 MGI:3607629 RGD:1582661 NCBI chr 6:55,204,602...55,244,217 JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISO (MGI:5294309|PMID:12468440) UniProt PMID:12468440 MGI:5294309 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GSS glutathione synthetase involved_in IEA
ISO
UniProt
RGD
PMID:10964706 GO_REF:0000041 RGD:1599340 NCBI chr24:23,973,807...24,000,281
Ensembl chr24:23,901,045...23,997,286
JBrowse link
G HAGH hydroxyacylglutathione hydrolase involved_in ISO (PMID:8550579) UniProt PMID:8550579 NCBI chr 6:39,076,364...39,105,646
Ensembl chr 6:39,084,513...39,105,592
JBrowse link
G MGST2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:8703034) UniProt PMID:8703034 NCBI chr19:3,067,062...3,070,579 JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in ISO (MGI:6478075|PMID:12614333) MGI PMID:12614333 MGI:6478075 NCBI chr 1:92,898,274...92,978,260
Ensembl chr 1:92,898,274...92,978,260
JBrowse link
G SLC1A2 solute carrier family 1 member 2 involved_in ISO (MGI:6478075|PMID:12614333) MGI PMID:12614333 MGI:6478075 NCBI chr18:32,565,258...32,717,052
Ensembl chr18:32,565,258...32,709,225
JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:5616326|PMID:14978030) ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3588610|PMID:16037214) Ensembl
MGI
PMID:16037214 GO_REF:0000107 MGI:3588610 NCBI chr19:4,289,792...4,379,060
Ensembl chr19:4,289,850...4,389,048
JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDH2 3-hydroxybutyrate dehydrogenase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr32:24,420,946...24,442,384
Ensembl chr32:24,420,951...24,442,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13875
    metabolic process 8978
      biosynthetic process 4553
        organic substance biosynthetic process 4459
          organonitrogen compound biosynthetic process 1291
            peptide biosynthetic process 541
              nonribosomal peptide biosynthetic process 13
                amino acid activation for nonribosomal peptide biosynthetic process + 1
                glutathione biosynthetic process + 11
                siderophore biosynthetic process + 1
                vancomycin biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 13875
    metabolic process 8978
      nitrogen compound metabolic process 7494
        cellular nitrogen compound metabolic process 4856
          cellular amide metabolic process 900
            peptide metabolic process 674
              peptide biosynthetic process 541
                nonribosomal peptide biosynthetic process 13
                  amino acid activation for nonribosomal peptide biosynthetic process + 1
                  glutathione biosynthetic process + 11
                  siderophore biosynthetic process + 1
                  vancomycin biosynthetic process 0
paths to the root