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ONTOLOGY REPORT - ANNOTATIONS


Term:nonribosomal peptide biosynthetic process
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Accession:GO:0019184 term browser browse the term
Definition:The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
Synonyms:exact_synonym: non-ribosomal peptide biosynthesis;   non-ribosomal peptide biosynthetic process;   non-ribosomal peptide formation;   non-ribosomal peptide synthesis;   nonribosomal peptide anabolism;   nonribosomal peptide biosynthesis;   nonribosomal peptide formation;   nonribosomal peptide synthesis
 related_synonym: nonribosomal peptide synthetase



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amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDH aminoadipate-semialdehyde dehydrogenase acts_upstream_of_or_within ISO (MGI:5630050|PMID:24467666) MGI PMID:24467666 MGI:5630050 NCBI chr 4:67,536,000...67,591,204
Ensembl chr 4:74,110,736...74,159,809
JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in
ISO (MGI:3607629|PMID:16081425)
(MGI:1858542|PMID:10805773)
(PMID:12663448)
(PMID:10395918), (PMID:8104187), (PMID:9675072)
RGD
MGI
UniProt
PMID:8104187 PMID:9675072 PMID:10395918 PMID:10805773 PMID:12663448 More... MGI:1858542 MGI:3607629 RGD:1582661 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit acts_upstream_of_or_within
involved_in
ISO (MGI:3607629|PMID:16081425)
(PMID:12081989)
(PMID:10395918), (PMID:9675072)
RGD
MGI
UniProt
PMID:9675072 PMID:10395918 PMID:12081989 PMID:16081425 PMID:16183645 MGI:3607629 RGD:1582661 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISO (MGI:5294309|PMID:12468440) UniProt PMID:12468440 MGI:5294309 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GSS glutathione synthetase ISO RGD PMID:10964706 RGD:1599340 NCBI chr20:31,256,734...31,284,356
Ensembl chr20:32,381,745...32,409,297
JBrowse link
G HAGH hydroxyacylglutathione hydrolase involved_in ISO (PMID:8550579) UniProt PMID:8550579 NCBI chr16:431,417...455,211 JBrowse link
G MGST2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:8703034) UniProt PMID:8703034 NCBI chr 4:132,031,087...132,106,864
Ensembl chr 4:143,338,016...143,412,966
JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in ISO (MGI:6478075|PMID:12614333) MGI PMID:12614333 MGI:6478075 NCBI chr 9:4,323,124...4,420,193
Ensembl chr 9:4,511,491...4,608,337
JBrowse link
G SLC1A2 solute carrier family 1 member 2 involved_in ISO (MGI:6478075|PMID:12614333) MGI PMID:12614333 MGI:6478075 NCBI chr11:35,223,811...35,392,799
Ensembl chr11:35,107,920...35,265,878
JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:5616326|PMID:14978030) ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:5616326|PMID:14978030) ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO (MGI:3588610|PMID:16037214) MGI PMID:16037214 MGI:3588610 NCBI chr 4:130,529,677...130,601,396
Ensembl chr 4:141,849,343...141,959,849
JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDH2 3-hydroxybutyrate dehydrogenase 2 involved_in ISO (MGI:4820913|PMID:20550936) UniProt PMID:20550936 MGI:4820913 NCBI chr 4:95,533,173...95,556,000
Ensembl chr 4:106,157,229...106,179,402
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12661
    metabolic process 7934
      biosynthetic process 4044
        organic substance biosynthetic process 3958
          organonitrogen compound biosynthetic process 1076
            peptide biosynthetic process 413
              nonribosomal peptide biosynthetic process 13
                amino acid activation for nonribosomal peptide biosynthetic process + 1
                glutathione biosynthetic process + 11
                siderophore biosynthetic process + 1
                vancomycin biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 12661
    metabolic process 7934
      nitrogen compound metabolic process 6601
        cellular nitrogen compound metabolic process 4263
          cellular amide metabolic process 731
            peptide metabolic process 524
              peptide biosynthetic process 413
                nonribosomal peptide biosynthetic process 13
                  amino acid activation for nonribosomal peptide biosynthetic process + 1
                  glutathione biosynthetic process + 11
                  siderophore biosynthetic process + 1
                  vancomycin biosynthetic process 0
paths to the root