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ONTOLOGY REPORT - ANNOTATIONS

Term:nonribosomal peptide biosynthetic process
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Accession:GO:0019184 term browser browse the term
Definition:The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
Synonyms:exact_synonym: non-ribosomal peptide biosynthesis;   non-ribosomal peptide biosynthetic process;   non-ribosomal peptide formation;   non-ribosomal peptide synthesis;   nonribosomal peptide anabolism;   nonribosomal peptide biosynthesis;   nonribosomal peptide formation;   nonribosomal peptide synthesis
 related_synonym: nonribosomal peptide synthetase


show annotations for term's descendants           Sort by:
amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdh aminoadipate-semialdehyde dehydrogenase acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5630050|PMID:24467666)
PMID:21873635		 RGD PMID:24467666 PMID:21873635 MGI:5630050, RGD:13792537 NCBI chr14:31,255,019...31,281,802
Ensembl chr14:31,255,310...31,281,796 		JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in
acts_upstream_of_or_within		 IMP
IBA
ISO
IEA
ISS		 PMID:21873635
MGI:2387010 (MGI:1858542|PMID:10805773), (MGI:3607629|PMID:16081425)
GO_REF:0000041
(PMID:10395918), (PMID:12663448), (PMID:8104187), (PMID:9675072)
GO_REF:0000024		 RGD
UniProt		 PMID:8104187 PMID:9675072 PMID:10395918 PMID:10805773 PMID:12663448 More... GO_REF:0000024 GO_REF:0000041 MGI:1858542 MGI:3607629, RGD:1582661, RGD:13792537 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA
IBA
ISS		 (MGI:3607629|PMID:16081425)
GO_REF:0000041
PMID:21873635
(PMID:10395918), (PMID:12081989), (PMID:9675072)
GO_REF:0000024		 RGD
UniProt		 PMID:9675072 PMID:10395918 PMID:12081989 PMID:16081425 PMID:16183645 More... GO_REF:0000024 GO_REF:0000041 MGI:3607629, RGD:1582661, RGD:13792537 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
IEA		 (MGI:5294309|PMID:12468440)
GO_REF:0000107		 RGD
Ensembl		 PMID:12468440 GO_REF:0000107 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ggt5 gamma-glutamyltransferase 5 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450 		JBrowse link
G Ggt6 gamma-glutamyl transferase 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:57,051,977...57,054,900
Ensembl chr10:57,051,825...57,067,260 		JBrowse link
G Ggt7 gamma-glutamyltransferase 7 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:143,978,073...144,004,597
Ensembl chr 3:143,978,082...144,001,492 		JBrowse link
G Gss glutathione synthetase involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000041
(MGI:81780|PMID:8660701)		 UniProt
RGD		 PMID:8660701 PMID:10964706 GO_REF:0000041 MGI:81780, RGD:1599340 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Hagh hydroxyacyl glutathione hydrolase involved_in IEA
ISO		 GO_REF:0000107
(PMID:8550579)		 Ensembl
RGD		 PMID:8550579 GO_REF:0000107 NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:8703034) RGD PMID:8703034 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:6478075|PMID:12614333) RGD PMID:12614333 MGI:6478075 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 involved_in ISO
IEA		 (MGI:6478075|PMID:12614333)
GO_REF:0000107		 RGD
Ensembl		 PMID:12614333 GO_REF:0000107 MGI:6478075 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:5616326|PMID:14978030) RGD PMID:14978030 MGI:5616326 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:5616326|PMID:14978030) RGD PMID:14978030 MGI:5616326 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (MGI:3588610|PMID:16037214) RGD PMID:16037214 MGI:3588610 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdh2 3-hydroxybutyrate dehydrogenase 2 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4820913|PMID:20550936)
PMID:21873635		 UniProt
RGD		 PMID:20550936 PMID:21873635 GO_REF:0000024 MGI:4820913, RGD:13792537 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    metabolic process 11509
      biosynthetic process 8045
        organic substance biosynthetic process 7987
          organonitrogen compound biosynthetic process 2109
            peptide biosynthetic process 1234
              nonribosomal peptide biosynthetic process 16
                amino acid activation for nonribosomal peptide biosynthetic process + 1
                glutathione biosynthetic process + 14
                siderophore biosynthetic process + 1
                vancomycin biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cellular metabolic process 10105
        cellular nitrogen compound metabolic process 6478
          cellular nitrogen compound biosynthetic process 5001
            amide biosynthetic process 1363
              peptide biosynthetic process 1234
                nonribosomal peptide biosynthetic process 16
                  amino acid activation for nonribosomal peptide biosynthetic process + 1
                  glutathione biosynthetic process + 14
                  siderophore biosynthetic process + 1
                  vancomycin biosynthetic process 0
paths to the root