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ONTOLOGY REPORT - ANNOTATIONS


Term:phthalate metabolic process
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Accession:GO:0018963 term browser browse the term
Definition:The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.
Synonyms:exact_synonym: phthalate metabolism;   phthalic acid metabolic process;   phthalic acid metabolism
 xref: UM-BBD_pathwayID:pth


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phthalate metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IEP di-(2-ethylhexyl)phthalate RGD PMID:16400681 RGD:5133250 NCBI chr 5:133,759,722...133,786,452
Ensembl chr 5:133,759,735...133,786,452
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP di(n-butyl) phthalate RGD PMID:18923996 RGD:2317622 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:16809437 RGD:1601046 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP di-(2-ethylhexyl) phthalate RGD PMID:20920559 RGD:4890045 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:20954080 RGD:4891498 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:16809437 RGD:1601046 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Th tyrosine hydroxylase IEP mono-(2-ethylhexyl) phthalate RGD PMID:21145954 RGD:5128805 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organic cyclic compound metabolic process 5931
          benzene-containing compound metabolic process 37
            phthalate metabolic process 7
              phthalate catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        organic acid metabolic process 1090
          oxoacid metabolic process 1061
            carboxylic acid metabolic process 1005
              dicarboxylic acid metabolic process 103
                phthalate metabolic process 7
                  phthalate catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.