Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:3-hydroxyacyl-CoA dehydratase activity
go back to main search page
Accession:GO:0018812 term browser browse the term
Definition:Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O.
Synonyms:xref: EC:4.2.1.74;   MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN;   RHEA:33767;   Reactome:R-HSA-2066778 "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA";   Reactome:R-HSA-2066780 "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA";   Reactome:R-HSA-389986 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA";   Reactome:R-HSA-390252 "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA";   Reactome:R-HSA-5676637 "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA";   Reactome:R-HSA-6809263 "EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA";   reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA"


show annotations for term's descendants           Sort by:
3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HACD1 3-hydroxyacyl-CoA dehydratase 1 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:43,901,590...43,929,441
Ensembl chr10:43,897,162...43,929,409 		JBrowse link
G HACD2 3-hydroxyacyl-CoA dehydratase 2 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr13:136,834,103...136,933,564
Ensembl chr13:136,834,115...136,933,549 		JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:163,525,872...163,567,649
Ensembl chr 1:163,525,965...163,588,798 		JBrowse link
G HACD4 3-hydroxyacyl-CoA dehydratase 4 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:201,885,874...201,910,667
Ensembl chr 1:201,886,332...201,910,664 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO RGD PMID:1730633 RGD:1600572 NCBI chr 3:112,753,343...112,797,627
Ensembl chr 3:112,752,865...112,797,733 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 enables ISO
IEA		 RGD
Ensembl		 PMID:8902630 GO_REF:0000107 RGD:10411904 NCBI chr 2:123,313,445...123,401,386
Ensembl chr 2:123,313,448...123,402,709 		JBrowse link
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HACD1 3-hydroxyacyl-CoA dehydratase 1 enables IEA UniProt GO_REF:0000003 NCBI chr10:43,901,590...43,929,441
Ensembl chr10:43,897,162...43,929,409 		JBrowse link
G HACD2 3-hydroxyacyl-CoA dehydratase 2 enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr13:136,834,103...136,933,564
Ensembl chr13:136,834,115...136,933,549 		JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 enables IEA UniProt
RHEA
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 1:163,525,872...163,567,649
Ensembl chr 1:163,525,965...163,588,798 		JBrowse link
G HACD4 3-hydroxyacyl-CoA dehydratase 4 enables IEA Ensembl
RHEA
UniProt		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 1:201,885,874...201,910,667
Ensembl chr 1:201,886,332...201,910,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18689
    catalytic activity 5662
      lyase activity 202
        carbon-oxygen lyase activity 80
          hydro-lyase activity 60
            enoyl-CoA hydratase activity 10
              3-hydroxyacyl-CoA dehydratase activity 6
                very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity 4
paths to the root