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ONTOLOGY REPORT - ANNOTATIONS

Term:protein C-terminal leucine carboxyl O-methyltransferase activity
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Accession:GO:0018423 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + [protein]-L-leucine = S-adenosyl-L-homocysteine + [protein]-L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
Synonyms:exact_synonym: protein-leucine O-methyltransferase activity
 narrow_synonym: protein phosphatase methyltransferase activity
 xref: reactome:R-HSA-8856945 "PP2A methylation by LCMT1"


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protein C-terminal leucine carboxyl O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcmt1 leucine carboxyl methyltransferase 1 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 105
          protein carboxyl O-methyltransferase activity 6
            protein C-terminal carboxyl O-methyltransferase activity 2
              protein C-terminal leucine carboxyl O-methyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            O-methyltransferase activity 25
              carboxyl-O-methyltransferase activity 6
                protein carboxyl O-methyltransferase activity 6
                  protein C-terminal carboxyl O-methyltransferase activity 2
                    protein C-terminal leucine carboxyl O-methyltransferase activity 1
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